Patents Assigned to Bayer
  • Pyrrolotriazine Derivatives Useful For Treating Hyper-Proliferative Disorders And Diseases Associated With Angiogenesis
    Publication number: 20070208013
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: June 3, 2005
    Publication date: September 6, 2007
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Julie Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea Mcclure, Benjamin Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold Kluender
  • Insecticidal proteins derived from
    Patent number: 7265268
    Abstract: The present invention relates to the field of plant pest control, particularly insect control. Provided are nucleotide sequences from Bacillus thuringiensis encoding insecticidal proteins. Further provided are methods and means for using said nucleotide sequence for controlling plant insect pests. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: September 4, 2007
    Assignee: Bayer BioScience N.V.
    Inventors: Greta Arnaut, Annemie Boets, Karel De Rudder, Stijn Vanneste, Jeroen Van Rie
  • Nucleic acids encoding a novel Cry2Ae bacillus thuringiensis insecticidal protein
    Patent number: 7265269
    Abstract: The invention pertains to novel insecticidal compounds derived from Bacillus thuringiensis strains. New proteins designated Cry2Ae, Cry2Af, and Cry2Ag, and variants thereof are provided, as well as DNA sequences encoding these proteins or their variants. Further provided are recombinant hosts expressing such proteins, particularly plant cells and plants.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: September 4, 2007
    Assignee: Bayer Bioscience N.V.
    Inventors: Greta Arnaut, Annemie Boets, Stijn Vanneste, Jeroen Van Rie, Sara Van Houdt
  • Monodisperse anion exchangers
    Patent number: 7265159
    Abstract: Process for preparing monodisperse weakly basic or optionally strongly basic anion exchangers of the poly(meth)acrylamide type, the ion exchangers themselves and their use.
    Type: Grant
    Filed: July 22, 2004
    Date of Patent: September 4, 2007
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Klipper, Olaf Halle, Claudia Schmid, Wolfgang Podszun, Rüdiger Seidel, Hans-Karl Soest
  • Anilinopyrazole derivatives useful for the treatment of diabetes
    Patent number: 7265144
    Abstract: The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: September 4, 2007
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Joachim Rudolph, Louis-David Cantin, Steven Magnuson, William Bullock, Ann-Marie Bullion, Libing Chen, Chih-Yuan Chuang, Sidney Liang, Dyuti Majumdar, Herbert Ogutu, Alan Olague, Ning Qi, Philip L. Wickens
  • Polycarbonate or polyester carbonate containing optical brighteners
    Patent number: 7265170
    Abstract: A thermoplastic molding composition characterized by its optical brightness and good weathering resistance is disclosed. The composition contains a poly(ester) carbonate an optical brightener conforming to where R1, R2, R3 R4, R5 and R6 independently denote H, alkyl, aryl, heteroaryl or halogen, or where R1, R2, R3, R4, R5, R6 and R7 mutually independently stand for H, alkyl, aryl, heteroaryl, halogen or a cyano group.
    Type: Grant
    Filed: September 24, 2003
    Date of Patent: September 4, 2007
    Assignee: Bayer MaterialScience AG
    Inventors: Rüdiger Gorny, Siegfried Anders, Wolfgang Nising, Marco Roelofs
  • Acylglycerol Acyltransferase-Like Protein Mgat-X2 And Uses Thereof
    Publication number: 20070202500
    Abstract: The present invention is directed to a polynucleotide and polypeptide sequence of a novel acylglycerol acyltransferase-like protein MGAT-X2. The invention also provides the human MGAT-X2 associated with the cardiovascular diseases, metabolic diseases, muscle-skeleton disorders or dermatological diseases. The invention also provides assays for the identification of compounds useful for the modulation of cardiovascular diseases, dermatological diseases, metabolic diseases or muscle-skeleton disorders for treating of cardiovascular diseases, metabolic diseases, muscle-skeleton disorders or dermatological diseases associated with expression of the MGAT-X2. The invention also features compounds which bind to and/or activate or inhibit the activity of MGAT-X2 as well as pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: September 16, 2004
    Publication date: August 30, 2007
    Applicant: Bayer Healthcare AG
    Inventors: Stefan Golz, Ulf Bruggemeier, Andreas Geerts
  • Diagnostics And Therapeutics For Diseases Associated With Arginyl Aminopeptidase Rnpep (Rnpep)
    Publication number: 20070202567
    Abstract: The invention provides a human RNPEP which is associated with the cardiovascular diseases, cancer, dermatological diseases, hematological diseases, neurological diseases, urological diseases, respiratory diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, cancer, dermatological diseases, hematological diseases, neurological diseases, urological diseases, respiratory diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of RNPEP as well as pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: September 16, 2004
    Publication date: August 30, 2007
    Applicant: Bayer Healthcare AG
    Inventors: Stefan Golz, Ulf Bruggemeier, Andreas Geerts, Stefanie Polej
  • Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-Halogen steroids and uses thereof
    Patent number: 7262023
    Abstract: A novel method of synthesis for the manufacture of upstream products for the production of compounds with general formulas 8, 10, and 12 is described. In this synthesis, compounds with general formula 4,B are produced in a microbiological reaction.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: August 28, 2007
    Assignee: Bayer Schering Pharma AG
    Inventors: Ludwig Zorn, Rolf Bohlmann, Norbert Gallus, Hermann Kuenzer, Hans-Peter Muhn, Reinhard Nubbemeyer
  • Diagnostics and therapeutics for diseases associated with kallikrein 8 (klk8)
    Publication number: 20070196372
    Abstract: The invention provides a human KLK8 which is associated with the cardiovascular diseases, dermatological diseases, neurological diseases, metabolic diseases, cancer disorders, urological diseases, gastroenterological diseases and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, dermatological diseases, neurological diseases, metabolic diseases, cancer disorders, urological diseases, gastroenterological diseases and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of KLK8 as well as pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: August 17, 2004
    Publication date: August 23, 2007
    Applicant: BAYER HEALTHCARE AG
    Inventors: Stefan Golz, Ulf Bruggemeier, Andreas Geerts, Stefanie Polej
  • Indoline derivatives
    Publication number: 20070197626
    Abstract: The present invention relates to novel indoline derivatives, to processes for their preparation and to their use in medicaments, in particular as potent PPAR-delta-activating compounds for the prophylaxis and/or treatment of cardiovascular disorders, in particular of dyslipidaemias, arteriosclerosis and coronary heart diseases.
    Type: Application
    Filed: August 16, 2004
    Publication date: August 23, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Elke Dittrich-Wengenroth, Stephan Siegel, Michael Woltering
  • Difluoromethanesulfonyl anilide derivatives useful as herbicides
    Publication number: 20070197390
    Abstract: Novel difluoromethanesulfonamide derivatives of the formula (I) Difluoromethanesulfonamide derivatives represented by the formula wherein X represents halogen, Y represents CH or N, R1 represents hydrogen, and R2 represents hydrogen or hydroxy, or R1 and R2 together may form C=O with the carbon atom to which they are bonded, and their use as herbicide for paddy field weeds.
    Type: Application
    Filed: March 19, 2005
    Publication date: August 23, 2007
    Applicant: Bayer Cropscience AG
    Inventors: Koichi Araki, Sachio Kudo, Yoshitaka Sato, Keiji Endo, Shinichi Shirakura, Shin Nakamura
  • Method for detecting a differentially expressed sequence
    Patent number: 7258973
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 21, 2007
    Assignees: Mayo Foundation for Medical Education & Research, Bayer Healthcare, LLC
    Inventors: Jon H. Astle, Christopher C. Burgess, Theodore J. Catino, Poornima Dwivedi, Marcia E. Lewis, Gary A. Molino, Susan H. Myerow, Arunthathi Thiagalingam, Stephen Thibodeau, Lawrence J. Burgart, Lisa Allyn Boardman
  • Methods and compositions for treating urological disorders using carboxypeptidase Z identified as 8263
    Patent number: 7258971
    Abstract: The present invention relates to methods for the diagnosis and treatment of a urological disorder or urological disorders. Specifically, the present invention identifies the differential expression of Carboxypeptidase Z, identified as “8263” gene in tissues relating to urological disorder, relative to their expression in normal, or non-urological disorder disease states, and/or in response to manipulations relevant to a urological disorder. The present invention describes methods for the diagnostic evaluation and prognosis of various urological diseases, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating a urological disorder or urological disorders. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of urological disorders.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: August 21, 2007
    Assignee: Bayer HealthCare AG
    Inventors: Venkateswarlu Karicheti, Inmaculada Silos-Santiago, Scott D. Eliasof
  • Diagnostics and therapeutics for diseases associated with kallikrein 13 (klk13)
    Publication number: 20070191296
    Abstract: The invention provides a human KLK13 which is associated with the hematological diseases, neurological diseases, metabolic diseases, endocrinological diseases, dermatological diseases, gastroenterological diseases, urological diseases, cancer disorders and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, neurological diseases, metabolic diseases, endocrinological diseases, dermatological diseases, gastroenterological diseases, urological diseases, cancer disorders and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of KLK13 as well as pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: August 17, 2004
    Publication date: August 16, 2007
    Applicant: Bayer Healthcare AG
    Inventors: Stefan Golz, Ulf Bruggemeier, Andreas Geerts, Stefanie Polej
  • Silylated carboxamides
    Publication number: 20070191454
    Abstract: Novel silylated carboxamides of the formula (I) in which R, L, R1, R2, R3, R4 and A are as defined in the description, a plurality of processes for preparing these compounds and their use for controlling unwanted microorganisms.
    Type: Application
    Filed: November 6, 2004
    Publication date: August 16, 2007
    Applicant: Bayer Cropscience Aktiengesellschaft
    Inventors: Ralf Dunkel, Hans-Ludwig Elbe, Benoit Hartmann, Alexander Klausener, Jorg Greul, Ulrike Wachendorff-Neumann, Peter Dahmen, Karl-Heinz Kuck
  • Method for producing alpha-fluoromalonic acid dialkyl esters
    Publication number: 20070191628
    Abstract: The invention relates to a new, advantageous method for the preparation of dialkyl ?-fluoromalonates.
    Type: Application
    Filed: August 13, 2004
    Publication date: August 16, 2007
    Applicant: Bayer Cropscience Aktiengesellschaft
    Inventors: Andreas Gunther, Holger Weintritt, Stefan Bohm
  • Substituted dihydroquinazolines
    Publication number: 20070191387
    Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
    Type: Application
    Filed: March 26, 2007
    Publication date: August 16, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Thomas Lampe, Susanne Nikolic, Jurgen Reefschlager, Rudolf Schohe-Loop, Frank Sussmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jorg Keldenich, Dieter Lang, Peter Nell
  • Antiparasitic artemisinin derivatives (endoperoxides)
    Publication number: 20070191354
    Abstract: This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substitued derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
    Type: Application
    Filed: January 9, 2006
    Publication date: August 16, 2007
    Applicant: Bayer Aktiengesellschaft
    Inventors: Richard Haynes, William Lam, Ho-Wai Chan, Hing-Wo Tsang, Man-Ki Cheung, Gisela Greif, Gabriele Schmuck, Arnd Voerste
  • Analyte-determining meter
    Patent number: D549343
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: August 21, 2007
    Assignee: Bayer HealthCare LLC
    Inventors: Julian Schlagheck, Markus Mottscheller, Jeffrey A. Culver, Barry D. Power, Eric Miller