Patents Assigned to Bayer
  • Plant growth regulation
    Publication number: 20070149406
    Abstract: The present invention relates to a new class of plant growth regulators. In particular, the invention relates to 5-substituted-1-arylpyrazole-3-carboxylic acid derivative of general formula (I) and a method for treatment of plants with such compounds in order to induce growth regulating responses.
    Type: Application
    Filed: December 15, 2004
    Publication date: June 28, 2007
    Applicant: Bayer CropScience GmbH
    Inventors: Henricus Bastiaans, Gunter Donn, Nathalie Knittel, Arianna Martelletti, Richard Rees, Michael Schwall
  • Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
    Patent number: 7235576
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: June 26, 2007
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy B. Lowinger, William J. Scott, Roger A. Smith, Jill E. Wood, Mary-Katherine Monahan, Reina Natero, Joel Renick, Robert N. Sibley
  • Polycarbonate moulding materials with anti-static properties
    Patent number: 7235598
    Abstract: A thermoplastic molding compositions comprising thermoplastic polycarbonate and an additive amount of an aluminum compound is disclosed. The aluminum compound is characterized by its particle size and the composition is characterized by its improved anti-static properties.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: June 26, 2007
    Assignee: Bayer MaterialScience AG
    Inventors: Michael Zobel, Thomas Eckel, Dieter Wittmann, Bernd Keller
  • 2786, a novel human aminopeptidase
    Patent number: 7235634
    Abstract: The present invention relates to a newly identified human aminopeptidase. The invention also relates to polynucleotides encoding the aminopeptidase. The invention further relates to methods using the aminopeptidase polypeptides and polynucleotides as a target for diagnosis and treatment in aminopeptidase-related disorders. The invention further relates to drug-screening methods using the aminopeptidase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the aminopeptidase polypeptides and polynucleotides. The invention further relates to procedures for producing the aminopeptidase polypeptides and polynucleotides.
    Type: Grant
    Filed: January 29, 2004
    Date of Patent: June 26, 2007
    Assignee: Bayer HealthCare AG
    Inventors: Rosana Kapeller-Libermann, David White, Kyle J. MacBeth
  • Process for the preparation of thioalkylamine derivatives
    Patent number: 7235668
    Abstract: The present invention relates to a novel process for the preparation of compounds of the formula (I) by reacting in a first step amino alcohols of the formula (II) with oleum to give sulphuric acid esters of the general formula (III) and by reacting these sulphuric acid esters in a second step with mercaptans or salts thereof of the general formula (IV) RSM ??(IV) wherein in each formula, where applicable, R1, R2, R3, R4, R5, R6, R, n and M have the meanings given in the disclosure, in the presence of a diluent and in the presence of a base.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: June 26, 2007
    Assignee: Bayer CropScience AG
    Inventor: Jörn Stölting
  • 4-HETEROARYL-TETRAHYDROQUINOLINES AND THEIR USE AS INHIBITORS OF THE CHOLESTERIN-ESTER TRANSFER PROTEIN
    Publication number: 20070142420
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Application
    Filed: February 22, 2007
    Publication date: June 21, 2007
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: JURGEN STOLTEFUSS, MICHAEL LOGERS, GUNTER SCHMIDT, ARNDT BRANDES, CARSTEN SCHMECK, KLAUS BREMM, HILMAR BISCHOFF, DELF SCHMIDT
  • Diagnostics and therapeutics for diseases associated with endothelial differentiation, sphingolipid g-protein-coupled receptor 6(edg6)
    Publication number: 20070141571
    Abstract: The invention provides a human EDG6 which is associated with the cardiovascular disorders, gastrointestinal and liver diseases, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders, urological disorders, thrombocytopenia and myeloma. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, gastrointestinal and liver diseases, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders, urological disorders, thrombocytopenia and myeloma. The invention also features compounds which bind to and/or activate or inhibit the activity of EDG6 as well as pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: March 17, 2004
    Publication date: June 21, 2007
    Applicant: BAYER HEALTHCARE AG
    Inventors: Stefan Golz, Ulf Bruggemeier, Andreas Geerts
  • Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes
    Publication number: 20070142444
    Abstract: A composition comprising at least a pyridylethylbenzamide derivative of general formula (I)(a) and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes (b) in a (a)/(b) weight ratio of from 0.01 to 20. A composition further comprising an additional fungicidal compound. A method for preventively or curatively combating the phytopathogenic fungi of crops by using this composition.
    Type: Application
    Filed: February 10, 2005
    Publication date: June 21, 2007
    Applicant: BAYER CROPSCIENCE S.A.
    Inventors: Marie-Claire Grosjean-Cournoyer, Jean-Marie Gouot
  • Active compound combinations having insecticidal properties
    Publication number: 20070142327
    Abstract: The invention relates to novel insecticidal active compound combinations comprising, firstly, anthrlamides (group 1) and, secondly, further insecticidal active compounds selected from the group of the (thio)phosphates (group 2) and/or the group of the carbamates (group 3), which combinations are highly suitable for controlling animal pests, such as insects.
    Type: Application
    Filed: November 20, 2004
    Publication date: June 21, 2007
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Christian Funke, Reiner Fischer, Rudiger Fischer, Heike Hungenberg, Wolfram Andersch, Wolfgang Thielert, Anton Kraus
  • Process for the preparation of 2-aminomethylpyridine derivative
    Patent number: 7232911
    Abstract: Process for the preparation of 2-aminomethylpyridine derivative of general formula (I), in which: n represents 0, 1, 2 or 3; X is halogen atom; Y may be the same or different and may be a halogen atom, a halogenoalkyl, a alkoxycarbonyl or a alkylsulphonyl
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: June 19, 2007
    Assignee: Bayer Cropscience S.A.
    Inventors: Manuel Vangelisti, Mehul Amin, Robert Pannell
  • Aqueous binder dispersions as coating compositions
    Patent number: 7232860
    Abstract: An aqueous binder dispersion that includes at least one copolymer (P) containing carboxylic acid and/or carboxylate groups. The copolymer (P) includes structural units of carboxyl-free (meth)acrylic esters with a cycloaliphatic structure, and at least 25 mol % of the carboxylic acid groups of the copolymer (P) in the dispersion being present in triethanolamine-neutralized form. The aqueous binder can be used in aqueous coating materials, which can be used to coat a substrate.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: June 19, 2007
    Assignee: Bayer MaterialScience AG
    Inventors: Martin Melchiors, Ulrich Freudenberg, Robert Reyer, Raul Pires, Sandra Grosskopf
  • Agents for combating plant pests
    Patent number: 7232840
    Abstract: The present invention relates to compositions for controlling plant pests containing the compound of formula (I) in a mixture with fungicidally active compounds, except for cyclopropylcarboxamide derivatives and azolylmethylcycloalkanes.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: June 19, 2007
    Assignee: Bayer CropScience AG
    Inventors: Christoph Erdelen, Wolfram Andersch, Klaus Stenzel, Astrid Mauler-Machnik, Wolfgang Krämer
  • Pyridine derivatives
    Patent number: 7232909
    Abstract: This invention is to provide a process for producing 2-amino-4,6-disubstituted nicotinic acid ester analogs and salts thereof, comprising the reaction shown by the following scheme. The ester analogs can be prepared in one pot, and in good yield by using tertiary alkyl cyanoacetate. Furthermore, the method is useful for preparing derivatives of various analogs of the ester, e.g. alkyl substituted and aryl substituted analogs.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: June 19, 2007
    Assignee: Bayer Aktiengesellschaft
    Inventors: Toshiki Murata, Masaomi Umeda, Sachiko Sakakibara, Takashi Yoshiro, Hiroki Sato, Tsutomu Masuda, Yuji Koriyama, Mitsuiyuki Shimada, Takuya Shintani, Hiroshi Kadono, Timothy B. Lowinger, Karl B. Ziegelbauer, Kinji Fuchikami, Hiroshi Komura
  • Active substance combinations comprising insecticidal and acaricidal properties
    Patent number: 7232845
    Abstract: The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: June 19, 2007
    Assignee: Bayer CropScience AG
    Inventors: Reiner Fischer, Thomas Bretschneider, Christoph Erdelen
  • Heliothis glutamate receptor
    Patent number: 7232658
    Abstract: The present invention is directed to a nucleic acid encoding a lepidopteran glutamate-gated chloride channel. Vectors and host cells comprising the nucleic acid are also provided. A method of identifying agents that modulate the activity of a lepidopteran glutamate-gated chloride channel is also provided. Such agents are useful as insecticides.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: June 19, 2007
    Assignee: Bayer CropScience AG
    Inventors: Xiao-Zhuo Michelle Wang, Xavier Georges Sarda, Michael David Tomalski, Vincent Paul Mary Wingate
  • Methods for prediction and prognosis of cancer, and monitoring cancer therapy
    Publication number: 20070134670
    Abstract: The present invention relates to biomarkers and the use of biomarkers for the prediction and prognosis of cancer as well as the use of biomarkers to monitor the efficacy of cancer treatment. Specifically, this invention relates to the use of stanniocalcin as a biomarker for VEGFR2 inhibitors.
    Type: Application
    Filed: December 10, 2004
    Publication date: June 14, 2007
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: James Kasper, Nicole Pauloski, Ian Taylor, James Elting, Timothy Sarr
  • Pyrazolyl-substituted heterocycles and their use as phytosanitary products
    Patent number: 7230116
    Abstract: The present invention relates to novel pyrazolyl-substituted heterocycles of the formula (I) in which X, Y, Z and Het are as defined in the disclosure, to processes for their preparation, and to their use as pesticides, microbicides and herbicides.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: June 12, 2007
    Assignee: Bayer CropScience, AG
    Inventors: Reiner Fischer, Astrid Ullmann, Thomas Bretschneider, Axel Trautwein, Ralf Wischnat, Angelika Lubos-Erdelen, legal representative, Dieter Feucht, Mark Wilhelm Drewes, Christoph Erdelen, deceased
  • Dihydropyridinone derivatives
    Patent number: 7230017
    Abstract: The invention relates to novel dihydropyridinone derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: June 12, 2007
    Assignee: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenich, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Antibacterial amide macrocycles
    Publication number: 20070129288
    Abstract: The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.
    Type: Application
    Filed: June 10, 2003
    Publication date: June 7, 2007
    Applicant: BAYER HEALTHCARE AG
    Inventors: Thomas Lampe, Isabelle Adelt, Dieter Beyer, Nina Brunner, Rainer Endermann, Kerstin Ehlert, Heinz-Peter Kroll, Franz Nussbaum, Siegfried Raddatz, Joachim Rudolph, Guido Schiffer, Andreas Schumacher, Yolanda Canco-Grande, Martin Michels, Stefan Weigand
  • Diagnostic and therapeutics for diseases associated with 5-hydroxytryptamine (serotonin) receptor 7 (5-ht7)
    Publication number: 20070128603
    Abstract: The invention provides a human 5-HT7 which is associated with the cardiovascular disorders, dermatological disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, dermatological disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of 5-HT7 as well as pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: May 15, 2004
    Publication date: June 7, 2007
    Applicant: BAYER HEALTHCARE AG
    Inventors: Stefan Golz, Ulf Bruggemeier, Andreas Geerts