Abstract: Substituted triazolinone compounds of the formula: wherein the variables R1, R2, R7, R8, R12 and X are as defined in the specification are useful as herbicides, plant growth regulators, insecticides and acaricides. Processes for the preparation of these compounds, and intermediates useful in such preparation are also disclosed.
Type:
Grant
Filed:
June 6, 1995
Date of Patent:
June 14, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Reiner Fischer, Uta Jensen-Korte, Franz Kunisch, Albrecht Marhold, Pieter Ooms, Otto Schallner, Hans-Joachim Santel, Robert-Rudolf Schmidt, Birgit Krauskopf, Robert-Harry Strang
Abstract: The invention provides diagnostic methods and kits including oligo and/or polynucleotides or derivatives, including as well antibodies determining whether a human subject is at risk of getting adverse drug reaction after statin therapy or whether the human subject is a high or low responder or a good a or bad metabolizer of statins. The invention provides further diagnostic methods and kits including antibodies determining whether a human subject is at risk for a cardiovascular disease. Still further the invention provides polymorphic sequences and other genes.
Type:
Application
Filed:
February 14, 2003
Publication date:
June 9, 2005
Applicant:
Bayer Healthcare AG
Inventors:
Udo Stropp, Stephan Schwers, Harald Kallabis
Abstract: The invention relates to particulate solids comprising more than 90% by weight of natural or synthetic surface-active compounds for which a) the mean particle size of the particulate solid particles is 10 to 3000 ?m, b) the surface-active compounds are solid at room temperature, and c) the surface-active compounds have a melting point of from 25 to 250° C.
Abstract: The present invention relates to light fast, aqueous, strippable coating compositions containing A) 40 to 90 wt. %, based on resin solids of A) and B), of aqueous polyurethane-polyureas and B) 10 to 60 wt. %, based on resin solids of A) and B), of polymers prepared from radically polymerizable monomers, wherein the percentages of A) and B) add up to 100, based on the weight of resin solids of A) and B). The present invention relates also to substrates coated with these strippable coating compositions. In addition, the present invention relates to the use of the stripped coatings as recycled material by mechanically comminuting the stripped coatings, optionally after cleaning, and then either pressing them in heatable presses to form sheets, or extruding them in an extruder to form endless thermoplastic threads, and then processing the resulting threads by known granulating methods to form cylindrical, spherical, lenticular or rhombic granules.
Type:
Grant
Filed:
March 5, 2001
Date of Patent:
June 7, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Hanns-Peter Müller, Horst Gruttmann, Joachim Petzoldt, Heino Müller, Christoph Irle
Abstract: The present invention relates to fluorinated benzaldehydes, to a process for preparing them and also to the use of the fluorinated benzaldehydes for preparing active ingredients, especially in medicaments and agrochemicals.
Abstract: The invention relates to novel pyrazolopyridine derivatives of formula (I) wherein R1 represents NH2 or NHCO-C1-6-alkyl, and R2 represents a radical of formula R3NCOR4 which is bonded to the remainder of the molecule by means of the nitrogen atom, R3 and R4 forming, together with the amide group to which they are bonded, a five to seven-membered heterocycle which may be saturated or partially unsaturated, may optionally contain a further heteroatom selected from the group N, O, and S and may comprise between one and five other substituents chosen from oxo, C1-6alkyl, hydroxyl, hydroxy-C1-6-alkyl, halogen, or may be fused to a C6-10 ARYL ring or a C3-8 cycloalkyl ring in which optionally two carbon atoms are bonded to each other by means of an oxygen atom.
Type:
Grant
Filed:
November 9, 2001
Date of Patent:
June 7, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
Abstract: This invention related to novel sulfonamide substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
Type:
Grant
Filed:
September 19, 2003
Date of Patent:
June 7, 2005
Assignee:
Bayer Pharmaceuticals Corporation
Inventors:
Gaetan H. Ladouceur, Richard D. Connell, Jeremy Baryza, Ann-Marie Campbell, Timothy G. Lease, James H. Cook
Abstract: Substituted and Fused pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1 and R2 may be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using these materials are also disclosed.
Type:
Grant
Filed:
August 10, 2000
Date of Patent:
June 7, 2005
Assignee:
Bayer Pharmaceuticals Corporation
Inventors:
Jacques P. Dumas, Stephen James Boyer, Teddy Kite Joe, Holia N. Hatoum-Mokdad, Harold C. E. Kluender, Wendy Lee, Dhanapalan Nagarathnam, Robert N. Sibley, Ning Su
Abstract: Segmented polyurethane/ureas useful in the production of spandex are produced by chain extending an isocyanate-terminated prepolymer in the presence of a solvent. The isocyanate-terminated prepolymer is formed by reacting a stoichiometric excess of an isocyanate with an isocyanate-reactive component that includes more than 50 equivalent percent of a high molecular weight polyoxyalkylene diol having an unsaturation level no greater than about 0.015 meq/g and up to about 50 equivalent percent of a polytetramethylene ether glycol.
Abstract: The present invention relates to a process for process for preparing a coating by a) applying to a porous and/or absorbent substrate a liquid coating composition containing at least one component having (meth)acryloyl groups and a dynamic viscosity of less than 2000 mPa.s and 0.1 to 10 wt. %, based on the non-volatile content of the coating composition, of an additive selected from polyamides, oligomeric fatty acid amides and polymeric fatty acid amides and b) polymerizing the composition with radiation. The present invention also relates to the resulting coated substrates and to the coating compositions used in the process.
Type:
Grant
Filed:
July 15, 2003
Date of Patent:
June 7, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Jan Weikard, Wolfgang Fischer, Manfred Müller
Abstract: Disclosed are pyrazolyl derivative compounds or purified stereoisomers or stereoisomer mixtures of said compounds and their salts or prodrug forms thereof which have structural formula (I) or (II): wherein the variables R, R1, R2, R5 and R6 are as defined in the specification. The compounds are useful for the treatment or prevention of diseases and/or behaviors involving the 5-HT2C receptor.
Type:
Application
Filed:
December 28, 2002
Publication date:
June 2, 2005
Applicant:
Bayer Pharmaceuticals Corporation
Inventors:
Gaetan Ladouceur, Emil Velthuisen, Soongyu Choi, Yamin Wang, Jeremy Baryza, Philip Coish, William Bullock, Roger Smith, Jinshan Chen
Abstract: It is intended to prevent glufosinate fine granule from a change or decrease in its herbicidal effect depending on climate conditions. Glufosinate is blended with other chemicals and then an adhesion aid is added thereto. The obtained mixture is formed into fine granule. Thus, a foliage treatment technique achieving a stable herbicidal effect is provided.
Type:
Application
Filed:
December 27, 2002
Publication date:
June 2, 2005
Applicants:
SUMITOMO CHEMICAL COMPANY, LIMITED, BAYER CROPSCIENCE
Abstract: The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) in which A, B, G, X, Y, Z and W are each as defined in the description, to processes and intermediates for their preparation and to their use as pesticides and herbicides.
Type:
Grant
Filed:
November 5, 2003
Date of Patent:
May 31, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Hermann Hagemann, Reiner Fischer, Christoph Erdelen, Ulrike Wachendorff-Neumann, Udo Schneider, Wolfram Andersch
Abstract: The invention relates to novel active compound combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties.
Type:
Grant
Filed:
March 15, 2001
Date of Patent:
May 31, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Reiner Fischer, Christoph Erdelen, Thomas Bretschneider
Abstract: The present invention relates to the preparation of nitrobenzoic acids by oxidizing particular nitrotoluenes, nitrobenzyl alcohols, esters and/or ethers in the presence of nitric acid at elevated temperature and elevated pressure. It has been found that the particular nitrotoluenes, nitrobenzyl alcohols, esters and/or ethers may be oxidized particularly reliably and in high yields using nitric acid to the benzoic acid derivatives when they are metered into the nitric acid.
Type:
Grant
Filed:
March 30, 2001
Date of Patent:
May 31, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Reinhard Langer, Lars Rodefeld, Karl Heinz Neumann
Abstract: The present invention relates to the use of 24-membered cyclodepsipeptides of the formula (1) in which R1 and R2 are as defined in the description, for controlling animal pests in veterinary medicine, hygiene, agriculture, forests and in the protection of materials, to pesticides comprising these depsipeptides and to novel depsipeptides of the formula (1).
Type:
Grant
Filed:
December 11, 2000
Date of Patent:
May 31, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Hubert Dyker, Wolfram Andersch, Christoph Erdelen, Peter Lösel, Ralf Nauen
Abstract: This invention pertains to methods for determining the presence or absence in Brassica plant material of elite event MS-B2, which is a specific transformation event of a construct comprising a male-sterility gene, at a specific location in the Brassica genome, using PCR and primers specific to the construct, and kits for use in the methods.
Abstract: Novel 4-Biarylbutyric and 5-Biarylpentanoic Acid Derivatives, use of substituted 4-Biarylbutyric and 5-Biarylpentanoic Acid Derivatives as Matrix Metalloprotease Inhibitors for the Treatment of Respiratory Diseases, pharmaceutical compositions containing them, and a process for using them. The compounds of the invention have the generalized formula (I) (T)xA—B—D—E—CO2H wherein A is an aryl or heteroaryl rings; B is an aryl or heteroaryl ring or a bond; each T is a substituent group, x is 0, 1, or 2; the group D represents (a), (b), (c), or (d); the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involved in ring formation, possible structures being shown in the text and claims; and each of the substituents on E is an independent substituent; and include pharmaceutically acceptable salts thereof.
Type:
Grant
Filed:
December 20, 1999
Date of Patent:
May 31, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Mary F. Fitzgerald, Philip J. Gardiner, Kevin Nash, Graham Sturton, Günter Benz, Rolf Henning, Karl-Heinz Schlemmer, Bernd Riedl, Helmut Haning, Lorenz Mayr
Abstract: A thermoplastic molding composition especially suitable for preparing optical data carriers is disclosed. The composition contains polycarbonate resin, at least one mold release agent and at least one phosphite having a defined structural formula. The optical data carriers include compact discs, video discs, digital versatile discs and further optical data carriers which may be written and erased one or more times.