Patents Assigned to Bayer
  • Patent number: 10028509
    Abstract: The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: July 24, 2018
    Assignee: Bayer CropScience AG
    Inventors: Ulrike Wachendorff-Neumann, Wolfram Andersch, Klaus Stenzel, Bernd Springer
  • Patent number: 10029220
    Abstract: A fluid path set includes a first fluid line having a proximal end fluidly connectable to a source of a first fluid and a second fluid line having a proximal end fluidly connectable to a source of a second fluid. A flow mixing device is in fluid communication with distal ends of the first and second fluid lines. The flow mixing device includes a housing, a first fluid port provided for receiving the first fluid, and a second fluid port for receiving the second fluid. A mixing chamber is disposed within the housing and is in fluid communication with the first and second fluid ports. A third fluid port in fluid communication with the mixing chamber for discharging a mixed solution of the first and second fluids. A turbulent flow inducing member is disposed within the mixing chamber for promoting turbulent mixing of the first and second fluids.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: July 24, 2018
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Ralph H. Schriver, Andreas Maihoefer, James A. Dedig, Michael A. Spohn, Herbert M. Grubic, Michael J. Swantner, Adam Caruso
  • Patent number: 10028508
    Abstract: The invention is in the technical field of vector control as well as insecticide-resistant mosquito and bed bug control. The active compound compositions of this invention are used against mosquitos and bed bugs which transmit disease pathogens or which annoy the well-being of humans and animals. The active compound compositions of this invention are in particular useful to overcome target-specific and/or metabolic-specific resistance of mosquitos and bed bugs and are biologically efficient on a variety of surfaces over an extended period of time.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: July 24, 2018
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Karin Horn, Rainer Sonneck, Arnoldus Vermeer, Sebastian Horstmann, Guenther Nentwig, Frederic Schmitt
  • Patent number: 10028460
    Abstract: The present invention relates to methods for separating hybrid seed from a mixture of hybrid seed and inbred seed. In particular, said hybrid seed and said inbred seed have different phenotypes allowing separation of said hybrid seed with non-invasive methods based on the differences in said phenotypes.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: July 24, 2018
    Assignees: Bayer CropScience AG, Bayer CropScience N.V.
    Inventors: Sigrid Weissmann, Elmar Alfons Weissmann, John Jacobs
  • Publication number: 20180202008
    Abstract: The present invention relates to means, methods and kits for the specific detection of the causing agent of powdery mildew on grapes, the fungus Erysiphe necator. More specifically, the methods according to the invention are quantitative methods based on quantitative Polymerase Chain Reaction.
    Type: Application
    Filed: July 8, 2016
    Publication date: July 19, 2018
    Applicant: Bayer SAS
    Inventors: Patrice DUBOURNET, Semcheddine CHERRAD, Sébastien VACHER
  • Publication number: 20180201690
    Abstract: The present invention provides immunoconjugates composed of antibodies, e.g., monoclonal antibodies, or antibody fragments that bind to mesothelin, that are conjugated to cytotoxic agents, e.g., maytansine, or derivatives thereof, and/or co-administered or formulated with one or more additional anti-cancer agents. The immunoconjugates of the invention can be used in the methods of the invention to treat and/or diagnose and/or monitor cancers, e.g. solid tumors, recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for the membrane-anchored, 40 kDa mesothelin polypeptide, which which is overexpressed in several tumors, such as pancreatic and ovarian tumors, mesothelioma and lung cancer cells.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 19, 2018
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Antje Kahnert, Kerstin Unterschemmann, Iring Heisler, Charlotte Christine Kopitz, Joachim Schuhmacher
  • Publication number: 20180201585
    Abstract: The present invention relates to benzimidazol-2-amines of general formula (I) in which R1, R2, R3, R4, R5, R6 and R7 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: July 12, 2016
    Publication date: July 19, 2018
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Olaf PANKNIN, Sven RING, Katja ZIMMERMANN, Roland NEUHAUS
  • Patent number: 10022453
    Abstract: The present application relates to novel antibody drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: July 17, 2018
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hans-Georg Lerchen, Sven Wittrock, Nils Griebenow, Beatrix Stelte-Ludwig, Anette Sommer, Sandra Berndt, Christoph Mahlert, Mario Lobell, Carsten Terjung, Simone Greven, Yolanda Cancho Grande
  • Patent number: 10022463
    Abstract: The invention provides an apparatus and a process for continuous virus inactivation. The apparatus for continuous virus inactivation in a product stream comprises a tube or hose 1 having an inlet 4 and an outlet 5 in each case connected to a product flow line 8 for conveying the product stream, where the tube or the hose 1 is curved and/or helically coiled with a number n of windings around a coil axis h and has one or more changes in direction and/or bends 2 in the coil axis h having an angle ? of from 45° to 180° to alter the direction of action of the normals of the centrifugal force and the apparatus is characterized by a Dean number>0 and a torsion parameter>0.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: July 17, 2018
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Martin Lobedann, Stephan Klutz, Safa Kutup Kurt
  • Patent number: 10023539
    Abstract: The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory substituted cyanoguanidine-pyrazolines of general formula (I) wherein R1, R2, R3, R4, R5, X and r have the meaning as described and defined herein, as well as to pharmaceutical compositions comprising compounds according to the invention and to their prophylactic and therapeutic use for hyper-proliferative disorders, in particular for cancer, respectively tumor disorders. The present invention furthermore relates to the use of SMYD2 inhibitors for benign hyperplasias, atherosclerotic disorders, sepsis, autoimmune disorders, vascular disorders, viral infections, neurodegenerative disorders, inflammatory disorders, atherosclerotic disorders and the control of male fertility.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: July 17, 2018
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Jeffrey Stuart Mowat, Timo Stellfeld, Carlo Stresemann, Roman Hillig, Silke Köhr, Detlef Stöckigt, Jörg Weiske, Thomas Brumby, Naomi Barak, Clara Christ, Antonius Ter Laak, Volker Badock, Rosemary Helen Crampton, Ian Stefanuti
  • Patent number: 10022493
    Abstract: A fluid injection system including an injector head having a syringe for delivering a fluid to a patient, a mounting structure pivotally connected to the injector head and configured to support the injector head above a surface, and a control system operationally coupled to the injector head for controlling an injection procedure is disclosed. The fluid injection system is provided with sensors to control various aspects of the fluid injection system, such as the establishment of a reference plane, the determination of a tilt angle of the injector head, and the determination of a temperature of an actuation system of the injector head.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: July 17, 2018
    Assignee: BAYER HEALTHCARE LLC
    Inventors: John D. Shearer, Jr., Christopher M. Scutt, Walter J. Grumski, Michael A. Spohn, Jarrell T. McWilliams, Arlie D. Long, III, Richard C. Morton
  • Patent number: 10021877
    Abstract: Primarily, the present invention relates to the use of substances of the formula (I) as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The invention furthermore relates to the novel herbicidal substances of the formulae (Ib) and (Ia). The present invention also relates to corresponding compositions comprising one or more of the herbicides of the formula (I) and further agrochemically active substances, and also to plant growth-regulating or herbicidal compositions comprising one or more of these compounds. Moreover, the present invention relates to processes for preparing the compounds of the formula (I).
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: July 17, 2018
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Marc Mosrin, Harald Jakobi, Hansjoerg Dietrich, Elmar Gatzweiler, Christopher Rosinger, Dirk Schmutzler
  • Patent number: 10023528
    Abstract: The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: July 17, 2018
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael Hahn, Thomas Lampe, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Volkhart Min-Jian Li, Eva-Maria Becker-Pelster, Friederike Stoll, Andreas Knorr, Elisabeth Woltering
  • Publication number: 20180193349
    Abstract: Described herein are pharmaceutical combinations and compositions comprising a) a 2,3-dihydroimidazo[1,2-c]quinazoline compound, or a salt thereof, and b) one more additional active agents. The pharmaceutical combinations described herein may be useful for treating non-Hodgkin's lymphoma (NHL), particularly 1st line, 2nd line, relapsed, refractory, indolent or aggressive non-Hodgkin's lymphoma (NHL); follicular lymphoma (FL); chronic lymphocytic leukemia (CLL); marginal zone lymphoma (MZL); diffuse large B-cell lymphoma (DLBCL); mantle cell lymphoma (MCL); transformed lymphoma (TL); or peripheral T-cell lymphoma (PTCL).
    Type: Application
    Filed: January 3, 2018
    Publication date: July 12, 2018
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ningshu LIU, Katja HAIKE, Juliane PAUL, Antje Margret WENGNER
  • Publication number: 20180194730
    Abstract: The present invention relates to 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate, to processes for its preparation, to pharmaceutical compositions comprising it and to its use in the control of disorders.
    Type: Application
    Filed: January 30, 2018
    Publication date: July 12, 2018
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Alfons GRUNENBERG, Juergen STIEHL, Katharina TENBIEG, Birgit KEIL
  • Patent number: 10016618
    Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: July 10, 2018
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Alan D. Hirschman, Arthur E. Uber, III, David M. Reilly, John F. Kalafut, Frederick W. Trombley, III, Steven J. Remis, Scott Griffith, Douglas Descalzi, Richard Dewit, David M. Griffiths, Marc A. Mabie, Mark Trocki
  • Patent number: 10015943
    Abstract: The cotton variety ST 6182GLT is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety ST 6182GLT with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of ST 6182GLT and to plants of ST 6182GLT reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from ST 6182GLT.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: July 10, 2018
    Assignee: Bayer CropScience, LP
    Inventor: Michael Robinson
  • Patent number: 10011557
    Abstract: The present invention relates to a novel method for preparing substituted biphenylamines.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: July 3, 2018
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Thomas Himmler, Lars Rodefeld, Jonathan Hubrich, Lutz Ackermann
  • Patent number: D822486
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 10, 2018
    Assignee: Bayer HealthCare LLC
    Inventors: Peter Brian Clarke, John Philip Kalinowsky, Ryan Boudreaux, James Troy Starkey, Michael Scott Carpenter, Theresa C. DeSantis, Anna Erixon, Lori King, Robert G. Petit, Martin S. Johnson, Steven Jackan, Eric S. Paszkowski
  • Patent number: D822489
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 10, 2018
    Assignee: Bayer HealthCare LLC
    Inventors: John Bischoff, William A. Bachman, Michael Scott Carpenter, Kimberly McCormack