Abstract: The invention relates to a device for vacuum stoppering a medical container. The device includes a main body defining an internal volume that has a variable pressure chamber configured to be connected to a vacuum pump. A stopper holder system is arranged in communication with the variable pressure chamber and is configured to receive and hold a stopper aligned with the direction of travel of a piston rod. A piston rod is moveable inside the internal volume of the main body along a longitudinal axis between a proximal rest position and a distal operative position wherein the piston rod pushes the stopper into the medical container. A container holder system provided in the main body, is arranged distally relative to the stopper holder system and in communication with the variable pressure chamber.

Abstract: A nest and tub arrangement for the storage of medical device components including a tub having a plurality of guide elements extending from at least one surface of the tub and into the interior of the tub, and at least one nest having a plurality of receptacles for the storage of a plurality of medical device components therein. The at least one nest is sized and configured for placement within the tub such that the plurality of guide elements align and removably retain the at least one nest within the tub.

Abstract: This nest comprises a plurality of breakable connecting bridges, a plurality of flanges arranged in a predetermined pattern and configured to form the flanges of the medical containers, the flanges being connected to the breakable connecting bridges, and a supporting structure attached to the breakable connecting bridges so as to support the flanges. The flanges are integrally formed with the breakable connecting bridges and the supporting structure.

Abstract: A medical injection system adapted for a single-handed injection, the medical injection device comprising a gas compartment configured to contain a gas, the gas compartment comprising a piston, a reservoir intended to contain a drug composition, the reservoir having a proximal portion and a distal portion provided with a fluid exit configured to receive an injection needle, wherein the piston can move proximally between a distal position defining a first volume of the gas compartment to a proximal position defining a second volume of the gas compartment smaller than the first volume, and wherein the gas compartment is in gas communication with the reservoir in order to force the drug composition through the fluid exit, when the piston is moved proximally.

Abstract: A nest (10) for the storage of medical device components, including a top surface (12), a bottom surface (14), and a plurality of receptacles (20) for the storage of a plurality of medical device components therein, wherein each of the plurality of receptacles (20) includes a sidewall portion (22) extending downward from the bottom surface (14) of the nest (10). The nest (10) further includes a plurality of openings (26) formed in the top surface (12) and a plurality of stacking pins (28) extending from the bottom surface (14). Each of the plurality of openings (26) is substantially aligned with a respective one of the plurality of stacking pins (28) so as to enable two or more nests (10) to be stacked vertically relative to one another via association between the openings (26) and the stacking pins (28).

Abstract: An injection device for injecting a composition contained in a medical container comprising: a body configured to receive the medical container in a fixed position relative to the body, spring-loaded piston rod translationally movable inside the body along a spring axis, between a proximal rest position and a distal operative position wherein the spring-loaded piston rod engages a stopper of the medical container, and a selective blocking mechanism comprising a braking member selectively tiltable relative to the piston rod between a blocking position wherein the braking member impinges on the piston rod so as to prevent any translational movement of the spring-loaded piston rod in a distal direction by a bracing effect and a releasing position wherein the braking member disengages from the piston rod so as to allow the piston rod to move towards the distal operative position under the spring force.

Abstract: A connector for connecting a medical injection device, including a barrel and a needle extending from a distal tip of the barrel, to a container including a septum includes an inner deformable cover and an outer rigid cover. The inner deformable cover extends along a cover axis and includes a proximal connection part configured to engage the distal tip of the barrel and a distal portion. The outer rigid cover encloses the inner deformable cover and includes a distal adaptor configured to engage the container. The outer cover is configured so the needle tip extends into the distal adaptor when the proximal connection part of the inner deformable cover engages the distal tip of the barrel. The outer rigid cover is fixed to the inner deformable cover. The inner deformable cover is compressible between a relaxed configuration and a compressed configuration.

Abstract: A drug storage and dispensing system that includes a packaging unit and an injection device for pre-filled containers having a needle shield and containing a medication is disclosed. The drug storage and dispensing system of the present disclosure provides for drug administration while minimizing the space occupied by such containers in the cold chain. The packaging unit minimizes the risk of a needle-stick injury, as a healthcare worker does not have to manually remove the needle shield. The injection device provides a novel way of auto-disabling a container, such as a syringe, as a plunger rod is not engaged with the container until the container is actually used. The drug storage and dispensing system provides for a reduction in the number of steps required to perform an injection, and thus a productivity and efficiency gain in mass immunization campaigns.

Abstract: This passive safety device comprises an inner needle shield having a proximal end configured to be sealed to a tip of an injection device, a distal portion configured to be pricked by a needle in a pre-use position and pierced by the needle in an injection position, and an energy storage portion configured to accumulate energy as the passive safety device passes from the pre-use position to the injection position and release energy as the passive safety device passes from the injection position to a safety position. The passive safety device further comprises a sleeve surrounding the proximal end, an outer needle shield having a proximal end slidably attached to the sleeve so that the outer needle shield is movable relative to the sleeve, and a lock configured to lock the outer needle shield in the safety position.

Abstract: A plastic flange for a medical container, the plastic flange defining an opening, the opening being surrounded by a peripheral collar, the collar providing a support to a user's fingers, wherein the flange comprises connecting means for connecting the flange to an external surface of a tubular barrel of the medical container, and wherein the flange further comprises a remotely readable electronic component for remote identification of the medical container, the remotely readable electronic component being embedded into the plastic flange.

Abstract: A drug delivery device includes a reservoir for containing a medical product, a distally projecting end-piece having an outer surface and a total length measured along a longitudinal axis of said end-piece, said end-piece defining an axial passageway for the transfer of said medical product contained in said reservoir, wherein a gripping surface is provided on a portion of said outer surface, said portion being located in a distal region of said end-piece, the length of said portion representing at most 40%, preferably less than 33%, of the total length of the end-piece. An assembly includes such a drug delivery device and an adaptor intended to be mounted onto the end-piece.

Abstract: The present invention relates to adaptor (30) for a drug delivery device having a reservoir (12) and a longitudinal tip (20), the adaptor (30) comprising a distal part defining a connecting ring (31) intended to receive a connector, and a proximal part defining a mounting ring (33) having an inner surface (34), the mounting ring (33) being shaped and configured such that, when the adaptor (30) is mounted around the longitudinal tip (20) of the drug delivery device, at least one annular space (38) is created between said inner surface (34) of the mounting ring (33) and said outer surface (20a) of the longitudinal tip (20), said at least one annular space (38) being able to accommodate an adhesive layer (40) in order to bond said adaptor (30) to said longitudinal tip. The invention further relates to a drug delivery device comprising such an adaptor.

Abstract: This packaging device includes a housing delimiting a storing chamber. The storing chamber includes a distribution aperture configured to allow passage of one of said medical containers outside the housing so as to allow a user to pick up this medical container. The packaging device also includes a sharps container positioned inside the storing chamber of the housing in a pre-use position, the sharps container being removable from the storing chamber so as to be put outside the housing in a collecting position wherein the sharps container allows collection of the used medical containers. The sharps container is configured to contain the plurality of medical containers in the pre-use position and comprises a spill-out window configured to allow the medical containers to fall down into the storing chamber when the sharps container is moved from the pre-use position to the collecting position.

Abstract: This holding device comprising a supporting plate, the supporting plate having an upper face, a lower face opposite the upper face, a plurality of openings arranged according to a predetermined pattern and each configured to receive a barrel of one of the medical containers, plurality of reinforcing ribs protruding from at least one of the upper and lower faces and extending between adjacent openings of the plurality of openings, and the plurality of reinforcing ribs comprises at least one oblique rib extending obliquely relative to a longitudinal direction of the supporting plate from one side to another side of the supporting plate and between two different pairs of adjacent peripheral openings.

Abstract: An adaptor includes a tubular body having a proximal region and a distal region, the proximal region configured to engage a distal tip of a drug delivery device and the distal region being configured to be connected to a connector. The distal region has a distal end delimiting a distal opening so as to permit introduction of the connector inside the distal region. The distal end is configured to be clamped to the connector when the connector is introduced inside the tubular body. The distal end includes a deformable element having a free end, which is configured to deform towards the proximal region when the connector is introduced inside the tubular body.

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

Abstract: The present invention relates to a protection device (1) intended to at least partially cover the needle (2) of an injection device, comprising: a support (3) of the protection device (1), a sleeve (4) movable axially in translation with respect to the support (3), an arrangement (14) for returning the sleeve (4) from an injection position to a protection position, an axial guidance arrangement (29, 30) for preventing the sleeve (4) from pivoting with respect to the support (3), one peg (6) directly and at least elastically, coupled longitudinally to the support (3) or the sleeve (4) and housed in a passageway (10) defining a first section (11) and a second section (12) followed by the peg (6) from a storage position to the injection position and then to the protection position, and a safety arrangement (21; 36, 34, 35) part of which being elastically deformable, arranged in a way as to prevent the peg from returning from the second section to the first section.

Abstract: The application relates to a needle protection assembly (1) comprising: —a supporting element (18) and a needle shield (8), —one locking element (20) located within said needle protection assembly (1) and not accessible to the user, —urging means (24) for displacing said needle shield (8), —a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and —said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.

Abstract: A packaging for medical devices, including a tub provided with a peripheral wall delimiting an upper opening, a sealing cover sealable on the upper opening of the tub, and a sealing film adapted to be positioned on the upper face of the sealing cover. The sealing film, including a protective foil, an adhesive layer extending over the protective foil, and a peelable sheet having a first portion extending over the adhesive layer opposite to a first portion of the protective foil. The first portions of the protective foil and peelable sheet are arranged in a retracted position uncovering the sealing cover.

Abstract: A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to a profile of a syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of contents of the syringe barrel.