Abstract: A packaging for storing a drug delivery device comprising a container provided at its distal end with a distal tip bearing a needle, the needle being covered by a shield, the packaging comprising: a support comprising: a first holding element configured for receiving at least part of the shield before use, a second holding element configured for receiving a distal part of the needle after use, and an envelope for receiving the drug delivery device, the envelope being closed by the support.

Abstract: A medical injection device for supporting a medical container, the medical container comprising a barrel adapted to contain a composition and a needle extending from a distal end of the barrel, wherein the medical injection device comprises: a body configured to receive at least a part of the medical container, a plunger axially movable relative to the body along an axis of the body, needle cover movable relative to the body along the axis, the needle cover being configured to move successively between storage position wherein the needle cover covers the needle, an injection position wherein the needle cover exposes at least partially the needle, a safety position wherein the needle cover covers the needle and is prevented from moving back to the injection position.

Abstract: The present invention relates to a device for vacuum and vent tube stoppering a medical container. The device includes a main body defining an internal volume that has a first variable pressure chamber configured to be connected to a vacuum pump, the main body being configured to receive the proximal end of a medical container so that said medical container is in communication with the first variable pressure chamber. A vent device including a vent tube is moveable inside the internal volume of the main body along a longitudinal axis between a proximal rest position and a distal operative position. A piston rod is moveable inside the internal volume of the vent tube along the longitudinal axis between a proximal rest position and a distal operative position. A container holder system is provided in the main body, in communication with the first variable pressure chamber.

Abstract: This holding device comprising a supporting plate, the supporting plate having an upper face, a lower face opposite the upper face, a plurality of openings arranged according to a predetermined pattern and each configured to receive a barrel of one of the medical containers, plurality of reinforcing ribs protruding from at least one of the upper and lower faces and extending between adjacent openings of the plurality of openings, and the plurality of reinforcing ribs comprises at least one oblique rib extending obliquely relative to a longitudinal direction of the supporting plate from one side to another side of the supporting plate and between two different pairs of adjacent peripheral openings.

Abstract: This packaging device comprises a first stage (2a) of supporting units (20) configured to support a first plurality of medical containers (100a) in a first plane, a second stage (2b) of supporting units (20) configured to support a second plurality of medical containers (100b) in a second plane parallel to said first plane, the first plane and the second plane being spaced apart from each other so that the distal ends (106) of the first plurality of medical containers (100a) extend between medical containers of the second plurality of medical containers (100b), and the supporting units (20) of the first and second stages (2a, 2b) being configured so that the medical containers of the first and second pluralities of medical containers (100a, 100b) are oriented in a same direction. The first stage (2a) of supporting units (20) is formed by a first plate-shaped nest and the second stage (2b) of supporting units (20) is formed by a second plate-shaped nest.

Abstract: An integrated system for injection including an injection device in electronic connection with a communication device is provided. The external communication device may be a handheld electronic device such as a Smartphone or a dedicated reader such as a reader capable of reading information contained on an RFID tag. The injection device includes a needle and a drug delivery portion enclosed within an external housing. Optionally, a plurality of sensors is affixed to the surface of the needle to collect data about the injection and physical characteristics of the patient. The data may be recorded on a data capture module. The electronic chip may be a readable and writable electronic chip such as a non-volatile memory chip. Alternatively, the electronic chip is a passive RFID tag. The injection device may further include a data transmitter for sending information obtained from the data capture module to the external communications device.

Abstract: Provided herein is a method to mimic and assess the chemical degradation risk of a biological product, in prefilled syringes (PFS), using a custom-designed mimetic peptide. Such method is also able to predict the susceptibility to degradation of biological product in solution in a container for medical usage.

Abstract: A medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod, the stopper being slidably disposed within the reservoir and sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap includes a body having a proximal end, a distal end, and a hemispherical member including a gripping component. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

Abstract: An inspection system having a light source able to illuminate a transparent cylinder, a mask able to block at least part of the light from the light source, the light source and the mask arranged such that, when the transparent cylinder is positioned in the system for inspection, the light source, the mask and the transparent cylinder are substantially aligned along an inspection axis perpendicular to the longitudinal axis of said transparent cylinder and the mask is interposed between the light source and the transparent cylinder to prevent illumination of a first portion of the transparent cylinder having a width smaller than the diameter of the transparent cylinder while allowing illumination of a second portion of the transparent cylinder, the mask configured to provide a contrast with a particle present in the first portion of the cylinder and illuminated by light refracted by the second portion of the cylinder.