Abstract: A medical injection device for supporting a medical container comprising a barrel and a needle tip extending from a distal end of the barrel, comprising: safety shield, first ring configured to be coupled to the medical container and configured to be biased in a proximal direction relative to the safety shield from an injection position in which a needle tip extends out of the safety shield to a safety position in which the needle tip is covered by the safety shield, and second ring rotatably movable relative to the first ring between locking position wherein the second ring maintains the first ring in the injection position and an unlocking position wherein the second ring releases the first ring thereby allowing the first ring to be urged into the safety position.

Abstract: A protective assembly includes a body for receiving the syringe; and a coupling device inside the body, rigidly connected to the barrel as regards to axial movement relative to the body. The coupling device includes an attaching element which can be either in an engaged state to axially fix the coupling device and the plunger rod, or in a release state in which the coupling device and the plunger rod are axially free relative to one another. The coupling device is axially movable in the body from a storage position to an injection position in which the needle extends beyond the body, and in which the attaching element can move towards the release state. The coupling device is axially movable in the body from the injection position towards a safety position, in which the needle is covered by the body.

Abstract: A medical injector including a cap remover or second cap is disclosed. The medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod and slidably disposed within the reservoir. The stopper being sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.

Abstract: A protection device for a needle comprising an inner casing defining a cavity and an outer casing surrounding the inner casing, wherein the outer casing is provided with stabilizing means capable of cooperating with a substantially horizontal surface of a support so as to maintain the inner casing in a substantially vertical direction, in which an access to the cavity is left free. An assembly comprising such a protection device and a needle fixed on the needle tip of a drug delivery device.

Abstract: A safety device for preventing needlestick injury with a needle, including a protective cap and a shield capable of pivoting from a storage position where it is interlocked with the protective cap, a retracted position where it gives access to the needle and a safety position where it covers the needle, wherein a cam surface of the shield and an engaging peg of the protective cap are arranged so that, when the safety device is mounted around the tip of a medical device, removing the protective cap from the tip by a distal movement displaces the shield from the storage position to the retracted position. A medical device including a tip provided with a needle including a needle point, wherein the medical device further includes a safety device.

Abstract: The invention relates to a protection device (1) for a needle (203) of a tip (201) of a drug delivery device (202), comprising: —fixing means (2) for fixing the protection device to said tip, —protective legs (4) capable of transitioning from a first configuration ration in which they cover the needle, to a second configuration in which the needle is exposed, and to a third configuration in which they cover the needle, via pivot links, —removable maintaining means for maintaining the protective legs in their first configuration, —retaining means (9, 10) for retaining the protective legs in their third configuration, said pivot links comprising elastic return means (5) for automatically transitioning the protective legs from their first configuration to their second configuration. The invention also relates to an assembly comprising a drug delivery device and said protection device, and to a method for manufacturing said protection device.

Abstract: The invention relates to a method for reducing an amount of sub visible particles in a pharmaceutical composition contained in a medical injection device comprising a container (1) including a barrel (10) lubricated with a lubricant coating (2) in contact with the pharmaceutical composition, and a stopper (14) in sliding engagement within the barrel (10), the container comprising a region (130, 121, 123) extending distally from the distal end (100) of the barrel which is not accessible to the stopper. During formation of said lubricant coating (2) on the inner wall of the barrel, the method comprises limiting lubricant from being deposited into said region (130, 121, 123) extending distally from the distal end (100) of the barrel.

Abstract: The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a body adapted to receive a medical container in a fixed position relative to the body. The injection device includes a spring-loaded piston rod translationally movable inside the body between a proximal rest position allowing inserting of the medical container in the body and a distal operative position wherein the piston rod engages a stopper of the medical container and pushes the stopper in the medical container. The injection device includes a blocking system comprising a locking member mounted on the body and configured to engage the piston rod. The piston rod includes a proximal end extending out of the body and configured to be pushed by the user in a distal direction to accelerate the movement of the piston rod to the distal operative position.

Abstract: Packaging for medical containers, including a tub having a peripheral wall, a sealing cover sealable on an opening of the tub and a sealing envelope able to protect the sealing cover. The sealing envelope includes: a lower sealing part, having a frame able to be sealed to the peripheral wall of the tub, and a bonding surface that extends outwards from the frame, and an upper sealing part sealed on the bonding surface to enclose the opening of the tub and the sealing cover.

Abstract: A packaging device is configured to support medical containers, the packaging device including a first nest including a first set of supporting units configured to support a proximal end of a first plurality of medical containers and a second nest including a second set of supporting units configured to support a proximal end of a second plurality of medical containers. The first set of supporting units and the second set of supporting units being configured to maintainer the first plurality of medical containers and the second plurality of medical containers in an inverted position relative to each other. The first nest further comprises apertures configured to maintain a distal end of the second plurality of medical containers while the second nest comprises apertures configured to maintain a distal end of the first plurality of medical containers.

Abstract: The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a body configured to receive the medical container in a fixed position relative to the body. The injection device includes a spring-loaded piston rod translationally movable inside the body along a spring axis. The injection device includes a lever pivotably mounted on the body about a first pivot axis orthogonal to the spring axis at a first distance form the spring axis. The injection device includes a selective blocking system coupled to the lever by a second pivot axis orthogonal to the spring axis. The lever is pivotable between a rest position. The selective blocking system engages the piston rod to prevent any translation movement of the piston rod and a second position wherein the selective blocking system releases the piston rod.

Abstract: The invention relates to a safety assembly having—an attachment ring attached to the tip of the container and—a safety device covering at least the distal end of the needle, the safety device attached to the attachment ring. The attachment ring has an inner ring having an inner face provided with a snap feature, which engages a complementary snap feature on the tip of the container to prevent axial movement of the inner ring with respect to the container. The snap feature moves radially to engage the complementary snap feature on the tip of the container; and an outer ring is fixed on the inner ring, with a sleeve portion surrounding at least a portion of the inner ring to prevent radial movement of the snap feature once the snap feature has engaged the complementary snap feature on the tip of the container.

Abstract: A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to a profile of a syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of contents of the syringe barrel.

Abstract: An injection device including a syringe including a barrel having a distal end and a proximal end and a tip provided on the distal end of the barrel, the barrel defining an internal bore extending from the proximal end to the distal end of the barrel; a luer lock adaptor including a body having a proximal end and a distal end, a reduced-diameter portion provided on the proximal end of the body, and a threading provided on an outer surface of the body, the reduced-diameter portion defining an opening to receive the tip of the syringe in a friction fit; and a needle hub including a body defining an inner cavity, a needle receiving portion extending distally from the body, and a skirt extending inwardly into the inner cavity.

Abstract: A syringe assembly including a syringe barrel having a first end, a second end, and a sidewall extending therebetween defining a chamber is disclosed. The syringe assembly includes a stopper disposed within the chamber of the syringe barrel and a plunger rod having an inner member engaged with the stopper and an outer member adapted for telescopic movement with respect to the inner member. The plunger rod is transitionable from a collapsed position, in which a portion of the inner member is nested within the outer member, to an extended position, in which the same portion of the inner member extends outside the outer member. The syringe assembly also includes a stop member configured for cooperation with a portion of the syringe barrel, upon relative movement of the outer member with respect to the inner member, to limit the outward travel of the plunger rod from the syringe barrel.

Abstract: The invention relates to a device for vacuum stoppering a medical container. The device includes a main body defining an internal volume that has a variable pressure chamber configured to be connected to a vacuum pump. A stopper holder system is arranged in communication with the variable pressure chamber and is configured to receive and hold a stopper aligned with the direction of travel of a piston rod. A piston rod is moveable inside the internal volume of the main body along a longitudinal axis between a proximal rest position and a distal operative position wherein the piston rod pushes the stopper into the medical container. A container holder system provided in the main body, is arranged distally relative to the stopper holder system and in communication with the variable pressure chamber.

Abstract: A cap remover for removing a cap covering a needle of a medical injector includes a body having an insertion portion at its proximal end configured to at least partially accommodate the cap, and a grabbing portion at its distal end having an internal cavity which includes an extraction member having a series of laminas extending radially and inwardly from a ring.

Abstract: The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a main body adapted to receive a medical container in a fixed position relative to the main body. The main body includes an inner wall provided with a toothed surface. The injection device includes a piston. The piston includes a first part and a second part. The first part includes an inner spring-loaded piston rod, and an outer piston body extending coaxially around the inner spring-loaded piston rod. The second part is arranged between the inner spring-loaded piston rod and the outer piston body, and is provided with a pressing member. The injection device includes an actuator connected to the second part of the piston. The actuator is adapted to selectively move the second part between the proximal first position portion and the distal second position.

Abstract: The invention relates to a safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly having: an attachment ring fixed to the tip of the container and a safety device to cover at least the distal end of the needle, the safety device attached to the attachment ring. The safety assembly has an attachment ring having an inner ring and an outer ring to be snapped onto each other, the inner ring having an inner recess for applying glue between the inner ring and the tip, and the inner ring and outer ring having mutually engaging elements preventing any rotation of the outer ring relative to the inner ring.

Abstract: An adapter for use with a drug delivery device having a reservoir for containing a product, the reservoir having a distally projecting end-piece defining a passageway for the transfer of the product from the reservoir, includes a collar engageable with the end-piece, an adaptor securing member limiting translational movement of the collar with respect to the end-piece once the collar is engaged with the end-piece, at least one adaptor anti-rotation member limiting the rotation of the collar with respect to the end-piece once the collar is engaged with the end-piece, at least one deactivating member neutralizing the adaptor anti-rotation member in response to a turning torque equal or greater than a predetermined value applied to the collar when the collar is engaged with the end-piece, thereby allowing the rotation of the collar with respect to the end-piece.