Abstract: A medical injector including a cap remover or second cap is disclosed. The medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod and slidably disposed within the reservoir. The stopper being sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.

Abstract: A syringe assembly includes a syringe barrel having a first end, a second end, and a sidewall extending between the first end and the second end. The syringe assembly further includes a stopper disposed within a chamber of the syringe barrel, a plunger adapter engaged with the stopper, and a plunger rod having first and second ends. The first end of the plunger rod is pivotally secured to the plunger adapter. The plunger rod has a pre-use position where the second end of the plunger rod is positioned adjacent to the syringe barrel, and a use position where the plunger rod is configured to displace the stopper relative to the syringe barrel. A recessed portion of the plunger adapter receives a portion of the first end of the plunger rod when the plunger rod is in the pre-use position and the use position.

Abstract: A tip cap assembly adapted to close a fluid passageway of a distally projecting tip of an injection system, said tip cap assembly including an elastomeric inner cap having a frustoconical protrusion extending proximally and having a proximal face; a rigid outer cap which is securely disposed around said elastomeric inner cap; the proximal face of the frustoconical protrusion having a diameter at least greater than the diameter of the fluid passageway of the injection system.

Abstract: Packaging for medical containers, including a tub having a peripheral wall, a sealing cover sealable on an opening of the tub and a sealing envelope able to protect the sealing cover. The sealing envelope includes: a lower sealing part, having a frame able to be sealed to the peripheral wall of the tub, and a bonding surface that extends outwards from the frame, and an upper sealing part sealed on the bonding surface to enclose the opening of the tub and the sealing cover.

Abstract: A syringe assembly including a syringe barrel defining a chamber having a stopper therein is disclosed. The syringe assembly includes a plunger rod associated with the stopper, the plunger rod includes an outer sleeve having a distal end interconnected to the stopper and a sidewall portion defining an opening therein. The plunder rod also includes an inner sleeve disposed within the outer sleeve including a longitudinally extending track in alignment with the opening in the outer sleeve. The inner sleeve is adapted for telescopic movement with respect to the outer sleeve. The plunger rod also includes a spring mounted in association with the inner sleeve. The syringe assembly further includes a holding mechanism associated with the plunger rod and configured for cooperation with the inner and outer sleeves. Relative movement between the inner and outer sleeves causes the plunger rod to transition from a collapsed position to an extended position.

Abstract: A syringe assembly for use as a pre-filled syringe is disclosed. The syringe assembly includes a syringe barrel defining a chamber and having a stopper disposed therein. A plunger rod includes an inner member engaged with a portion of the stopper and an outer member adapted for rotational advancement with respect to the inner member to axially displace the outer member with respect to the inner member. The plunger rod is transitionable from a collapsed position in which a portion of the inner member is nested within the outer member, to an extended position in which the same portion of the inner member extends outside the outer member. The inner member includes a radial extension and the outer member defines a helical track adapted to receive the radial extension therein.

Abstract: An adaptor for connecting a drug delivery device to a needleless access device having a straight external thread, including engagement means for mounting said adaptor on the drug delivery device, and an internal thread intended to cooperate with said external thread on a determined length, said internal thread showing on a distal part of said length a first major diameter mating that of said straight external thread, wherein said internal thread shows on a proximal part of said length a second major diameter, where the second major diameter is strictly smaller than the first major diameter, said internal thread further including a tapered portion linking said proximal part to said distal part.

Abstract: Disclosed herein is a method to evaluate the stability of a protein-based formulation including a protein, a peptide and/or a protein derivative and a buffer relative to a lubricant of a lubricated container in which the formulation is intended to be stored, including: a) Evaluating a decrease over time of interfacial tension between the buffer and the lubricant, b) Evaluating a decrease over time of interfacial tension between the protein-based formulation and the lubricant, c) Identifying at least one component of the protein-based formulation interacting with the lubricant by comparing the decrease evaluated in step b) with the decrease evaluated in step a).

Abstract: The invention relates to a safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly having: an attachment ring fixed to the tip of the container and a safety device to cover at least the distal end of the needle, the safety device attached to the attachment ring. The safety assembly has an attachment ring having an inner ring and an outer ring to be snapped onto each other, the inner ring having an inner recess for applying glue between the inner ring and the tip, and the inner ring and outer ring having mutually engaging elements preventing any rotation of the outer ring relative to the inner ring.

Abstract: A cap remover for removing a cap covering a needle of a medical injector includes a body having an insertion portion at its proximal end configured to at least partially accommodate the cap, and a grabbing portion at its distal end having an internal cavity which includes an extraction member having a series of laminas extending radially and inwardly from a ring.

Abstract: The present invention relates to adaptor (30) for a drug delivery device having a reservoir (12) and a longitudinal tip (20), the adaptor (30) comprising a distal part defining a connecting ring (31) intended to receive a connector, and a proximal part defining a mounting ring (33) having an inner surface (34), the mounting ring (33) being shaped and configured such that, when the adaptor (30) is mounted around the longitudinal tip (20) of the drug delivery device, at least one annular space (38) is created between said inner surface (34) of the mounting ring (33) and said outer surface (20a) of the longitudinal tip (20), said at least one annular space (38) being able to accommodate an adhesive layer (40) in order to bond said adaptor (30) to said longitudinal tip. The invention further relates to a drug delivery device comprising such an adaptor.

Abstract: A medical injector is disclosed. The medical injector includes an upper guard housing having a gripping component, a lower guard housing defining a reservoir, and a stopper engaged with a portion of the upper guard housing, the stopper being slidably disposed within the reservoir and sized to provide sealing engagement with an interior sidewall of the lower guard housing. The upper guard housing at least partially surrounds the lower guard housing and is moveable relative to the lower guard housing to advance the stopper through the reservoir.

Abstract: The invention relates to an adaptor for coupling with a medical container closed by a septum, the adaptor comprising:—a gripping member (20) for securing the adaptor to the medical container,—a needle access port intended to face an outer surface of the septum,—a pierceable elastomeric piece (50) having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess (51) with a proximal opening and an outer wall (54) in contact with the needle access port,—attaching means for maintaining the elastomeric piece into the needle access port. The invention also relates to an assembly comprising such an adaptor and a medical container, and to the use of such an adaptor for preventing the contamination inside a medical container closed by a septum.

Abstract: An inspection system for detecting a particle in a transparent cylinder having a longitudinal axis and a diameter includes a light source able to illuminate a transparent cylinder, a mask able to block at least part of the light coming from the light source, the light source and the mask being arranged such that, when the transparent cylinder is positioned in the system for inspection, the light source, the mask and the transparent cylinder are substantially aligned along an inspection axis perpendicular to the longitudinal axis of said transparent cylinder and the mask is interposed between the light source and the transparent cylinder so as to prevent illumination of a first portion of the transparent cylinder having a width smaller than the diameter of the transparent cylinder while allowing illumination of a second portion of the transparent cylinder, the mask being configured to provide a contrast with a particle present in the first portion of the transparent cylinder and illuminated by light refracted

Abstract: The invention relates to a transportation system for annealing a glass container having a barrel and two extremities, said transportation system including a lath provided with at least two non-metallic inserts, the at least two non-metallic inserts being positioned such that, when a glass container is seated on said transportation system, said glass container is exclusively held by contact between said at least two non-metallic inserts and said barrel in substantially horizontal position which is fixed relative to the lath. The transportation system further includes securing means configured to reversibly firmly secure a clipping portion of said at least two non-metallic inserts into a respective slot of the lath.

Abstract: The invention provides a syringe assembly comprising a syringe barrel having an inside surface defining a chamber, an open proximal end, and a distal end having an opening therethrough. An elongated plunger rod extends between a first end and a second end, with a cap or guard disposed on the first end of the plunger rod. A plunger head extends within the chamber of the syringe barrel, and is adapted for slidable movement within the syringe barrel between the proximal end and the distal end, with the second end of the plunger rod connected with the plunger head through a pivotable connection. The plunger rod is adapted to pivot with respect to the plunger head between a first position in which the guard is adjacent the distal end of the syringe barrel and a second position in which the plunger rod is in general axial alignment with the syringe barrel, and is further adapted for axial movement so as to cause sliding movement of the plunger head through the syringe barrel to expel contents thereof.

Abstract: A syringe assembly having a flexible and/or slidable flange is provided, wherein in a pre-use or packaged state, the flange is positioned substantially parallel to a barrel of the syringe assembly resulting in the syringe assembly having a smaller packaging footprint. The smaller packaging footprint allows for a reduced storage space of the syringe assembly. Upon removal from a packaging and/or the storage space, the flange can be slid and locked into place such that the flange extends in a perpendicular direction with respect to a longitudinal axis of the barrel of the syringe assembly to allow for a traditional operation of the syringe assembly.