Patents Assigned to Becton
  • Patent number: 12157913
    Abstract: Disclosed herein include systems, methods, compositions, and kits for 5?-based gene expression profiling. Some embodiments provide synthetic particles (e.g., beads) associated with a first plurality of oligonucleotide barcodes and a second plurality of oligonucleotide barcodes. In some embodiments, nucleic acid targets (e.g., mRNAs) are initially barcoded on the 3? end with the first plurality of oligonucleotide barcodes and subsequently barcoded on the 5? end following a template switching reaction and intermolecular hybridization with the first plurality of oligonucleotide barcodes and extension. Immune repertoire profiling methods are also provided in some embodiments.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: December 3, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Katherine Lazaruk
  • Patent number: 12156990
    Abstract: A system and method is provided for detecting fluid low-volume and occlusion in a device using force sensing resistor (FSR) sensor. One or more force sensing resistors are positioned in communication with a fluid channel at one or more of a pump intake and pump outlet to detect pressure in the fluid channel. The pressure is detected through communication with the force sensing resistor and indicates an irregular system condition including but not limited to, fluid low-volume level and occlusion. Also provided are a fluid flow sensor (e.g., FSR or MEMS sensor) disposed relative to an embedded fluid channel in the base of a wearable medicine delivery pump.
    Type: Grant
    Filed: August 17, 2023
    Date of Patent: December 3, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Alessandro Pizzochero, J. Richard Gyory, Joseph Iskandar
  • Patent number: 12156989
    Abstract: A technical solution for monitoring operation of a medical delivery device such as an infusion pump for occlusion is provided that employs sensing pump motor current and monitoring average motor current difference as between dispense and aspirate strokes in a pump cycle. The solution can be implemented alone or in combination with other occlusion sensing methods that use one or more of pump measurement data such as pump stroke duration (e.g., duration of aspirate stroke or dispense stroke in a rotational metering-type pump or a reciprocating-type pump), end-stop or limit switch activation, and duration difference between aspirate and dispense strokes to detect occlusion.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: December 3, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Ling Zheng, Mojtaba Kashef, Uzair Siddiqui, Jinyan Li, Kepei Sun, Joseph Iskandar, Elizabeth Gurin
  • Publication number: 20240390664
    Abstract: A female Luer fitting disinfection device comprises a container comprising a bottom surface, a side wall, and an open end; a porous foam insert disposed within the container, the porous foam insert comprising a central region. A plug is positioned within the central region, the plug sized and shaped to fit within a lumen of the female Luer fitting, and a liquid disinfectant is in the container and absorbed within the porous foam insert. A sealing web covering the open end of the container. A method of disinfecting a female Luer fitting is also provided.
    Type: Application
    Filed: May 26, 2023
    Publication date: November 28, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Manish Kumar, Shishir Prasad, Praveen Nalawade, Karthik MR
  • Publication number: 20240390577
    Abstract: Drug delivery device, drug delivery system, and system components are provided including configuration of a container, reservoir or barrel for medium or fluid and a pump mechanism or driving components for advancing a plunger to dispense the medium or fluid from the reservoir or barrel, and/or for filling the reservoir or barrel with the medium or fluid, where the pumping mechanism or driving components are disposed such that individual and/or overall dimensions of the pump mechanism or the driving components can be reduced compared to conventional designs. A provided system can include a syringe-style drug container, reservoir, or barrel containing a medium or fluid which can be dispensed by a pumping mechanism configured to advance a plunger/stopper disposed inside the barrel via cable, or a ribbon, connected to the plunger/stopper.
    Type: Application
    Filed: September 23, 2022
    Publication date: November 28, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Alessandro PIZZOCHERO, Mark WOOD
  • Patent number: 12150912
    Abstract: A connection system for connecting a first medical device component to a second medical device component is disclosed. The connection system of the present disclosure provides for quick and intuitive coupling and decoupling of two opposing medical device components through the use of a connection path and a disconnection path, the connection path being distinct from the disconnection path. Furthermore, the connection system of the present disclosure provides audible and tactile connection feedback through the use of elastically deformable connection elements.
    Type: Grant
    Filed: January 18, 2021
    Date of Patent: November 26, 2024
    Assignee: Becton Dickinson and Company Ltd.
    Inventors: Milan Ivosevic, Paul Paia Marici
  • Patent number: 12151077
    Abstract: A connector caps that can reduce risk of accidentally removing the cap include a locking feature where outer housing is designed to prevent removal of the cap unless a downward force is applied to the cap with counter clockwise rotation. Structural elements making up the cap locking feature can be optimized or varied, for example to require application of more or less force, more or less downward movement, more or less rotational movement, and variations of other characteristics to facilitate intentional removal and/or to prevent unintentional removal of the cap from the needleless connector, and/or to facilitate securing of the cap on the needleless connector. Optionally, a needleless connector cap can include an outer housing providing holes or openings or vents such that air can pass through if the cap becomes lodged in air passage way.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: November 26, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Kevin Ryan
  • Patent number: 12151078
    Abstract: A connector includes an outer housing defining a lumen, a first male coupler mateable with a needle-free valve and positioned at a first end of the outer housing, a second male coupler positioned at a second end of the outer housing, a valve system to control fluid flow through the lumen, and an actuator movable within the outer housing between a first position and a second position. A pinch clamp of the connector operates to selectively deflect locking fingers of the actuator from a locked position to a movement position to selectively enable or prevent movement of the actuator from the first position to the second position. The actuator, based on its positioning in the first or second position, causes the valve system to be in a closed state or an open state and blocks or allows the first coupler to couple with the needle-free valve.
    Type: Grant
    Filed: November 14, 2022
    Date of Patent: November 26, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Raymond P. Feith, Jason Andrew Wine
  • Patent number: 12151090
    Abstract: The passive safety device comprises a sleeve having a proximal end configured to be secured to a distal tip of the injection device, a hub slidably mounted onto the sleeve between a pre-use position, an injection position wherein the hub is proximally located with regard to the pre-use position, and a safety position wherein the hub is distally located with regard to the injection position, a biasing element configured to urge the hub distally towards the safety position, and a protector configured to slide together with the hub relative to the sleeve between the pre-use position and the injection position. The safety device may be configured to block a distal movement of the protector when the hub is in the injection position so that the protector is prevented from sliding back together with the hub in a distal direction.
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: November 26, 2024
    Assignee: Becton Dickinson Holdings Pte. Ltd.
    Inventor: Manicavasagam Ganapathy
  • Patent number: 12151035
    Abstract: A multi-chamber package is described including a first and second chamber, the first chamber having a bottom wall and sidewalls defining a cavity, the second chamber having a partially open bottom wall and sidewalls defining a cavity. A first removable seal is positioned over a top surface of the package, fully covering the first chamber and second chamber, and a second seal is positioned over a bottom surface of the partially open floor of the second chamber, fully sealing the second chamber. A method of packaging medical devices is also described.
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: November 26, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Kevin M. Ryan, Marco Antonio Ortiz Shields
  • Patent number: 12153043
    Abstract: Disclosed herein include methods, compositions, and kits suitable for spectral unmixing and compensation in multi-parameter flow cytometry. Disclosed herein include reagents which comprise two antibodies conjugated to one another to form a bispecific reagent (e.g., a bispecific probe). A first antibody can have affinity for a highly expressed antigen on the surface of a cell of interest and a second antibody can have affinity for each of the antibody-dye conjugates in a multi-parameter panel. There are provided, in some embodiments, methods of using the bispecific reagent to determine spillover, perform compensation, and generate a compensation matrix.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: November 26, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Jody Martin, James Ghadiali, Mirko Corselli, Adam Wright, Aaron Jacob Tyznik
  • Patent number: 12144603
    Abstract: Devices, systems, and methods are described including an invasive medical device with a magnetic region. The magnetic region can include a discontinuity in the magnetic region providing a diameter transition, a plurality of spaced magnetic regions can be provided or the magnetic regions can be encoded with data. Systems and methods are described that include ways to read the data.
    Type: Grant
    Filed: October 16, 2023
    Date of Patent: November 19, 2024
    Assignee: Becton, Dickinson and Companu
    Inventors: S. Ray Isaacson, Edward G. Henderson, Siddarth Shevgoor, Jonathan Karl Burkholz
  • Patent number: 12144941
    Abstract: A support device to support a catheter assembly may include a platform, which may include an upper surface and a bottom surface. The support device may include an extension element coupled to the upper surface of the platform. The extension element may include a distal end, which may include a first connector configured to couple to the catheter assembly, and a proximal end, which may include a second connector. The extension element may include a valve that may be movable between a first position and a second position. In response to the valve being moved to the first position, a fluid pathway extending through the cannula and the extension element may be open and straight. In response to the valve being moved to the second position, the fluid pathway may be closed. The support device may include a cannula, which may be swaged within the extension element.
    Type: Grant
    Filed: February 8, 2023
    Date of Patent: November 19, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Curtis H. Blanchard, Tyler Warner, Weston F. Harding
  • Patent number: 12138431
    Abstract: Described is a catheter patency maintenance device comprising of a flush syringe, an elongate plunger rod with a stopper slidably positioned within the barrel, a cap, disinfectant and a valve movable between an open position and a closed position. The valve may include a valve stem and/or openings in the valve to permit fluid flow. Methods of using the flush syringe assemblies are also described.
    Type: Grant
    Filed: December 2, 2022
    Date of Patent: November 12, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Girum Yemane Tekeste
  • Patent number: 12138421
    Abstract: A medication delivery device includes an infusion pump system having a reservoir, a fluid path connected between the reservoir and an insertion mechanism, a plunger arranged inside the reservoir, and a pump drive mechanism coupled with the reservoir. The medication delivery device further includes a processing device configured to determine a user fill volume of a fluid medication by analyzing a location of the plunger inside the reservoir when a fill of the fluid medication is completed. The processing device is configured to determine the user fill volume of the fluid medication by sensing a pressure inside the reservoir.
    Type: Grant
    Filed: February 2, 2022
    Date of Patent: November 12, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Scott Stewart, Abigail Kruegle, Muzaffer Ozsecen, J. Richard Gyory
  • Publication number: 20240369587
    Abstract: An analyzer for analysis of a biological sample prepared by a pre analytical system and a method of operating an analyzer that received samples prepared by a pre-analytical system. The analyzer is automated and has a processing deck with a plurality of modules serviced by a plurality of multichannel pipettors. Due to the high volume of pipette tips used by and dispensed from the multichannel pipettors, the processing deck has a pipette dispense assembly having a plurality of chutes, so that a multichannel pipettor does not need to wait to discard a pipette tip into a chute. The plurality of chutes allows the pipette tips to fall therethrough to a waste receptacle below the processing deck. The processing deck also includes a plurality of drawers that contain bins for consumable pipette tips to be used by the multichannel pipettors. Some of the drawers have multiple bins and some have only one bin because the location of the chutes does not permit all drawers to have the same depth.
    Type: Application
    Filed: September 6, 2022
    Publication date: November 7, 2024
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventors: Stephen Robert LaChance, Gerard J. Lotz, Philip Thomas Miller
  • Patent number: 12133975
    Abstract: A needle hub for a drug delivery device includes a needle holder and a needle attached to the needle holder, a needle actuation assembly configured to move the needle holder from a retracted position, to an insertion position, and back to the retracted position, and a pressure interlock comprising an inlet configured to be in fluid communication with a fluid source, an outlet in fluid communication with the needle, and a lock member. The lock member having a first position where the lock member prevents actuation of the needle actuation assembly and a second position where the lock member allows actuation of the needle actuation assembly. The lock member is moved from the first position to the second position based on a pressure within the pressure interlock.
    Type: Grant
    Filed: January 5, 2022
    Date of Patent: November 5, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Steve Beguin, Patrick Le Gal Redon, David James Coleman, Danielle Aboud, Sean McGrath, Marko Plevnik, Nathan Lyell, Harry Robert Lester
  • Patent number: 12135274
    Abstract: Outlet fittings are provided. Outlet fittings of interest include an elongate structure and an opening at a proximal end for receiving a flow stream from the distal end of a flow cell. In addition, the outlet fittings described herein are configured to reduce the formation of bubbles at the interface between the outlet fitting and the flow cell. In certain cases, outlet fittings do not include a planar surface in contact with the received flow stream. Flow cytometers and methods employing the subject outlet fittings are also provided.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: November 5, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Kyle Dembski
  • Patent number: 12135272
    Abstract: Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: November 5, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Albert Mach, Smita Ghanekar, Marja Suni
  • Patent number: D1050149
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: November 5, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Leslie Wilson, Zachary Wentworth, Thomas James Klemz