Abstract: A catheter system may include a catheter adapter and a wing extending outwardly from the catheter adapter. The wing may include a groove or slot. The catheter system may include a needle hub and a paddle extending outwardly from the needle hub. The paddle may include an extension disposed within the groove or the slot to reduce axial movement between the catheter adapter and the needle hub, which may be advantageous during insertion of the catheter system into a patient. The extension may be removable from the groove or the slot to allow axial movement between the catheter adapter and the needle hub during removal of the needle hub from the catheter adapter, for example. The paddle and/or the wing may include a shape to reduce axial movement between the catheter adapter and the needle hub, which may also be advantageous during insertion of the catheter system.

Abstract: Aspects of the present disclosure include systems for detecting light from a particle in a flow stream by spectral discrimination. Light detection systems according to certain embodiments include a wavelength separator component configured to propagate light between a first set of linear variable optical filters and a second set of linear variable optical filters where each set of linear variable optical filters is configured to pass light having predetermined sub-spectral ranges and a plurality of photodetectors positioned to detect light from each sub-spectral range across the linear variable optical filters. Systems having a light source for irradiating a particle in a flow stream and a photodetector modulator component for binning data signals generated in a plurality of photodetector channels of the light detection system are also described. Methods for detecting light with the subject systems and kits having one or more components for detecting light according to the subject methods are also provided.

Abstract: An analyzer for analysis of a biological sample prepared by a pre-analytical system and a method of operating an analyzer that receives biological samples for processing. The analyzer is automated and has a housing in which the biological samples are processed for analysis. The analyzer has an inventory control system for consumables used in the analyzer. The consumables are stored on and below a processing deck in the analyzer. The inventory control system can include racks for selectively storing consumables below deck, machine-readable labels on the processing deck for managing consumables thereon, and a support plate for the sample processing plates that manage waste from the processing plates. The analyzer includes an inventory robot disposed in the housing that includes an inventory scanner and an end-effector that is configured to handle a variety of consumables and is used for calibration.

Abstract: A fillable medicament delivery device, including a body, a reservoir disposed on the body and having an end wall, and a plunger movably disposed within the reservoir. The device also includes an input port and an output port disposed on one of the end wall and the plunger, and a patient cannula fluidly connected with the output port. The one of the end wall and the plunger has a face oriented toward an interior of the reservoir and the remaining one of the end wall and the plunger, and the face has a channel recessed therefrom. The channel fluidly connects the input port and the output port.

Abstract: Disclosed are systems and methods for a computerized framework that electronically manages and controls a patient's therapy for proper administration of diabetic treatment. The framework includes a disposable pen injector that has integrated therein dose logging capabilities (e.g., a NFC circuit) for controlling the administration of the prescribed therapy. Electronic communications between the disposable pen injector and a therapy control application executing on a patient's device can effectuate accurate and efficient administration of prescribed therapy. The pen can communicate information to the patient's device, and the application executing thereon, that includes dosage information related to availability left in the pen, timing of doses, and the like. In a related manner, the application can compile dosage planning information that can dictate types of doses, amounts of doses, timing of doses, and the like, to ensure that the patient is complying with a prescribed diabetic prescription.

Abstract: A flush syringe and integrated swab assembly comprises a chamber and a tip having a passageway. The assembly includes a plunger rod and an integral swab including an integral collar extending from the distal wall of the barrel, surrounding the distal tip, and having a collar distal end and a collar proximal end, the integral collar including at least one sidewall having an inside surface including an inner thread thereon defining a Luer lock area and configured to connect to the hub of a vascular access device connector, the at least one sidewall further having an outside surface including an outer thread thereon configured for connection to the removable cap that when connected to the integral collar covers the integral collar to protect the distal tip and the collar from contamination, and a porous hollow mass connected to the inner thread of the integral collar.

Abstract: A device (1) for obtaining a biological sample that includes a blood collection device (10) and a vibration device (80) removably attachable to the blood collection device that provides pain relief is disclosed. The vibration device of the present disclosure provides pain relief to a patient by vibrating the blood collection device. The vibration device can be attached to the blood collection device before it is placed onto a finger to provide pain relief during the finger lancing as well as to aid blood flow from the finger into a collection container during the collection process.

Abstract: A fluid delivery device has a syringe barrel-type reservoir with plunger and plunger driver assembly comprising nested, telescopic screws comprising an innermost screw keyed to a first side of the plunger or intermediate pusher to prevent rotation. In a fully retracted position, the nested screws do not extend into the reservoir. The nested screws all have right handed threads and employ the same pitch in their respective inner thread and outer thread designs. The outermost screw is connected to a motor for controllable rotation. The decreasing torque ratios from the outermost to innermost screw member and anti-rotation feature allows the innermost screw to advance the plunger into the reservoir before the adjacent concentric screw member commences rotating and advancing within its corresponding screw, and so on, to translate the plunger and expel fluid in a fluid chamber defined on the other, second side of the plunger.

Abstract: A needle actuator assembly for a drug delivery system includes a needle actuator body having a guide surface, a needle shuttle having a cam surface, with the needle shuttle moveable along a vertical axis between a first position and a second position. The needle shuttle is configured to move between the first and second position through engagement between the guide surface of the needle actuator body and the cam surface of the needle shuttle. The assembly further including a needle received by the needle shuttle.

Abstract: A catheter system may include a catheter adapter, which may include a body and a nose extending distally from the body. The nose may be generally cylindrical. A strain relief rib may be disposed on the nose. The strain relief rib may be constructed of a flexible material. A bump may be disposed on the strain relief rib and configured to contact a needle cover. A catheter may be secured within the catheter adapter and extend distally beyond the nose.

Abstract: A device for connection to a medical connector, the device includes a cap having an annular wall having an exterior wall surface and an interior wall surface including a plurality of inwardly extending protrusions sized and shaped to frictionally engage a male luer, and a peelable seal. The cap configured to define a chamber to contain an absorbent material and disinfectant or antimicrobial agent. The cap includes one or more threads adapted to engage with a female luer connector. The cap is adapted to engage a male luer connector in a press-fit connection. The peelable seal prevents the disinfectant or the antimicrobial agent from exiting the chamber. Also described are methods of disinfecting a medical connector, and apparatuses comprising a device for disinfecting a medical connector.

Abstract: A universal add-on for an injection pen is provided. A static portion (110) has opposing gripping members to grip a body (112) of the injection pen. A moving portion (106) has opposing gripping members to grip an actuator (114) of the injection pen. Displacement measurement devices (102) measure relative linear and rotational movement of the actuator relative to the injection pen body (112). Doses are determined and recorded based on relative movement of the static portion (110) and moving portion (106), and the dose data is transmitted wirelessly to a mobile device. The device is easily installed on injection pens by pressing opposing buttons to relieve gripping pressure imparted by the gripping members.

Abstract: A cap for connection to a medical connector comprises: a housing, a protrusion, a disinfection sponge, and a pressure seal. The protrusion includes an inner thread on an inner surface, the inner thread being sufficient to interlock with a mating feature of a female medical connector. The inner surface of the protrusion defines a second cavity. The protrusion includes an outer thread on an outer surface, the outer thread being sufficient to interlock with a mating feature of a male medical connector. The disinfection sponge is disposed on the second cavity. The pressure seal is attached to the housing and disposed adjacent to a surface of the disinfection sponge. The pressure seal can comprise a flexible insert attached to an interior surface of the top wall of the housing. The pressure seal can comprise a combination of: an elongate member and an insert that is slidably engaged with the elongate member.

Abstract: Disclosed herein are methods and systems for correcting errors in sample amplification, including the errors occurred in determining the number of targets in samples. In some embodiments, the method comprises: stochastically barcoding a plurality of targets in the samples using oligonucleotides comprising stochastic barcodes to generate stochastically barcoded targets; contacting one or more defined barcoded primers with each of the one or more samples; and determining an amplification noise.

Abstract: A catheter assembly and/or an introducer may include one or more features configured to guide a probe and/or a catheter distally through a septum. The catheter assembly may include a catheter adapter and the septum. The catheter adapter may include a distal end, a proximal end, and a lumen extending therebetween. In some embodiments, the septum may be disposed within the lumen. The septum may include a proximal surface that is tapered inwardly in a distal direction such that the proximal surface of the septum is configured to guide the probe and/or the catheter distally through the septum. The catheter assembly may be configured to receive an introducer, which may include an introducer element. A proximal end of the introducer element may include another proximal surface that is tapered inwardly in the distal direction such that the other proximal surface is configured to guide the probe or the catheter distally through the septum.

Abstract: A biological sample is provided, wherein the biological sample is a liquid-based cytology sample. A slide is placed in a holder. The slide is pre coated with a composition that will cause cells to adhere to the slide. A settling chamber is placed over the slide and the settling chamber is locked onto the holder. The settling chamber has openings in both proximate and distal ends. The opening in the distal end of the settling chamber is positioned over the slide. A density reagent is then dispensed into the settling chamber. The liquid-based cytology sample is then dispensed into the settling chamber over the reagent. The assembly formed by the holder, slide and settling chamber (and its liquid contents) is placed in a centrifuge. The density reagent and the liquid thereover are decanted from the settling chamber. The settling chamber is removed from over the slide.

Abstract: A medication delivery device comprising a base plate engaging a cover to form an interior, the interior including a pump drive mechanism for driving medication through the device, a drivetrain engaged to the pump drive mechanism, a magnetic encoder including an encoder hub mechanically coupled to the drivetrain, the encoder hub including a magnet, and a sensor that measures a magnetic field from the magnet to determine a rotational position of the drivetrain.

Abstract: A fluid delivery device (FDD) has a reservoir, a driver assembly, and a controller to controllably deliver fluid from the reservoir into a patient. The controller is configured to support dosing control and other operations of the fluid delivery device by a connected auxiliary device such as a smartphone or other portable remote control device. Active safety features are provided for commands to the fluid delivery device that comprise: (1) at least anomaly detection for inputted FDD commands and prompt for confirmation of anomalous commands prior to commanded operation of the FDD; and (2) an optional secondary communication path or modality for the confirmation that is different from a first communication path or modality used to communicate the command to the FDD.

Abstract: A container assembly including a collection container and a container lid couplable to the collection container. A specimen collection tube holder having an elongated receptacle formed therein is provided, the elongated receptacle being configured to receive a specimen collection tube. The specimen collection tube holder is removably couplable to a central portion of the container lid such that at least a portion of the elongated receptacle extends into the chamber of the collection container when the container lid is coupled to the collection container and the specimen collection tube holder is coupled to the container lid.