Abstract: This nest comprises a plurality of breakable connecting bridges, a plurality of flanges arranged in a predetermined pattern and configured to form the flanges of the medical containers, the flanges being connected to the breakable connecting bridges, and a supporting structure attached to the breakable connecting bridges so as to support the flanges. The flanges are integrally formed with the breakable connecting bridges and the supporting structure.

Abstract: A delivery device for delivering an instrument into a catheter assembly may include a syringe, which may include a barrel and a plunger movable within the barrel. The plunger may include a handle and a stopper coupled to a distal end of the handle. The stopper may include a channel. The delivery device may include a guidewire disposed within the barrel and extending through the channel. In response to depression of the plunger, the guidewire may move through the channel and a first end of the guidewire may be advanced in the distal direction. A second end of the guidewire may be fixed.

Abstract: Aspects of the present disclosure include methods for identifying a set of fluorophore-biomolecule reagent pairs for characterizing a sample by flow cytometry. Methods according to certain embodiments include calculating a spectral spillover spreading parameter for a plurality of fluorophores, pairing each fluorophore with a biomolecule that is specific for a biomarker of a cell in the sample to generate a plurality of fluorophore-biomolecule reagent pairs, generating an adjusted spillover spreading matrix for the fluorophore-biomolecule reagent pairs based on the spectral spillover spreading parameter of each fluorophore and a biomarker classification parameter and identifying an optimal set of fluorophore-biomolecule reagent pairs based on the calculated spillover spreading values from the adjusted spillover spreading matrix. Systems and non-transitory computer readable storage medium for practicing the subject methods are also provided.

Abstract: A disinfection tip is described for disinfecting a threaded connector of a syringe.

Abstract: An automated analyzer that receives samples prepared for analysis in an automated pre-analytical module and a method of operation of such automated analyzer. The automated analyzer includes a shuttle transfer station that receives a shuttle carrier from the automated pre-analytical system. The shuttle transfer station has a clamping assembly for the shuttle. The clamping assembly has jaws that advance engagement members into contact with a bottom portion of sample containers disposed in the shuttle. The clamping assembly secures the sample containers in the shuttle when sample is aspirated from the sample containers. The automated analyzer also has a multichannel puncture tool that is adapted to be carried by a robotic gripper mechanism. The multichannel puncture tool has multiple puncture members that each defines a channel Each channel is in communication with a different trough in the consumable. A pipette can pass through the channel in the puncture tool.

Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).

Abstract: A pressure switch is provided and includes an elastic membrane disposed such that pressure from fluid within a fluid path deforms the elastic membrane toward a plunger, thereby moving the plunger. The plunger is disposed between the membrane and an upper plate and is moveable along an axis extending between the membrane and the upper plate. A threshold pressure on the membrane from the fluid within the fluid path deforms the membrane, thereby moving the plunger toward the upper plate.

Abstract: A priming assembly for a drug delivery device includes a hub, a base connected to the hub and moveable relative to the hub between a first position and a second position, with the base defining a passageway, a cap defining an interior chamber and a passageway in fluid communication with the interior chamber, and a needle connected to the hub and positioned within the interior chamber of the cap, where the passageway of the base is in fluid communication with the passageway of the cap when the base is in the first position, and where the passageway of the base is isolated from the passageway of the cap when the base is in the second position.

Abstract: A flow sensor sub-assembly for sensing flow of a fluidic medicament includes a flow tube having an inlet and an outlet, a first coupler secured to the inlet of the flow tube, a second coupler secured to the outlet of the flow tube, a first piezo element secured to the first coupler, a second piezo element secured to the second coupler to define a predetermined distance between the first piezo element and the second piezo element, and at least one absorber sleeve engaged with the first coupler, the flow tube, and the second coupler.

Abstract: Aspects of the present disclosure include methods for adjusting a particle classification index in response to one or more saturated data signals from light detected from particles in a flow stream. Methods according to certain embodiments include detecting light from particles in a flow stream; generating a plurality of data signals from the detected light; identifying one or more saturated data signals; generating a saturated signal index that corresponds to the identified saturated data signals; and applying the saturated signal index to a particle classification index to generate an adjusted particle classification index. In some embodiments, methods include determining one or more parameters of a particle (e.g., for use in a particle sort decision) by calculating an adjusted spectral unmixing matrix for the fluorescence of the particle that excludes one or more saturated data signals. Systems and integrated circuit devices (e.g.

Abstract: A system may include a flow sensor and a base. The flow sensor may be configured to connect to the base. The flow sensor may include a flow tube including a fluid inlet at a first end of the flow tube, a fluid outlet at a second end of the flow tube opposite the first end of the flow tube, and a fluid injection port between the first end and the second end of the flow tube. The base may include a short range wireless communication device including a curved coil antenna.

Abstract: A syringe adapter includes a housing having a first end and a second end positioned opposite the first end, with the housing defining a passageway, and a connector body having a first end and a second end positioned opposite the first end, with the connector body having a connection member configured to be secured to a mating connector. One of the housing and the connector body includes a tab and the other of the housing and the connector body defines a channel that receives the tab, with the connector body movable relative to the housing between a first position where the connector body is restricted from rotating relative to the housing in a first rotational direction and free to rotate relative to the housing in a second rotational direction, and a second position where the connector body is free to rotate in the first and second rotational directions.

Abstract: An automatic picking machine for pharmaceutical drug packages includes at least one storage rack, at least one storage and retrieval machine, a control apparatus for controlling the storage and retrieval machine, and a filling apparatus for successively filling each of a plurality of transport containers with a group of pharmaceutical drug packages corresponding to one order, wherein the filling apparatus includes a plurality of collection containers, first transport apparatuses, each having a transport channel for conveying the pharmaceutical drug packages towards the respective collection container, and a receiving apparatus for receiving a transport container to be filled at a filling location of the filing apparatus.

Abstract: Picking devices for operating a picking devices for medicaments are provided. A picking device includes multiple storage spaces for medicament packaging, an operating device movable horizontally in an X-direction and vertically in a Z-direction in front of the storage spaces in a movement space, and an identification device configured for identifying medicament packaging. An optical detection device is configured to create an overall image of the movement space and a control device is coupled to the operating device, the identification device and the optical detection device, wherein the control device is configured to determine the presence of an obstacle in a portion of the movement space and to control the operating device based on the determined presence of the obstacle. Methods of operating picking devices for medicaments are also provided.

Abstract: A fluid delivery device has a syringe barrel with reservoir chamber for fluid, a plunger that translates along a longitudinal axis to expel fluid, and a pusher dimensioned to translate within the barrel and coupled to a drive mechanism to controllably contact and move the plunger. The pusher contacts the plunger at its mechanical center to reduce tilt in the plunger. Contact faces of the pusher and plunger cooperate as a ball joint to minimize non-axial forces on the plunger face. The pusher can have a protrusion of various lengths extending toward and being at least partially received in a recess of various depths in the plunger. The pusher is rigidly connected to a drive mechanism for anti-rotation. The pusher can have scalloped edges for air venting, and apertures for cooperating with protrusions on the drive mechanism to prevent bottoming out the plunger when filling.

Abstract: A transportation tray to transport filled syringes, the tray including a front shelf spaced apart from a rear shelf, with the front shelf and the rear shelf being on approximately the same plane. The front shelf includes at least one set of paired flexible fingers, the paired flexible fingers being spaced apart sufficiently to accommodate a barrel of a syringe and to thus hold the syringe on the tray.

Abstract: A nest (10) for the storage of medical device components, including a top surface (12), a bottom surface (14), and a plurality of receptacles (20) for the storage of a plurality of medical device components therein, wherein each of the plurality of receptacles (20) includes a sidewall portion (22) extending downward from the bottom surface (14) of the nest (10). The nest (10) further includes a plurality of openings (26) formed in the top surface (12) and a plurality of stacking pins (28) extending from the bottom surface (14). Each of the plurality of openings (26) is substantially aligned with a respective one of the plurality of stacking pins (28) so as to enable two or more nests (10) to be stacked vertically relative to one another via association between the openings (26) and the stacking pins (28).

Abstract: Water solvated polymeric dyes and polymeric tandem dyes having a blue excitation spectrum are provided. The polymeric dyes are conjugated polymers that can include a thiophene-containing co-monomer. The polymeric tandem dyes further include a signaling chromophore covalently linked to the conjugated polymer in energy-receiving proximity therewith. Also provided are labelled specific binding members that include the subject polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.

Abstract: Systems and methods are provided for selecting colony locations. Selecting colony locations can include determine a location of a selection tool on a culture plate image, determining a location of a potential source of error on the culture plate image, comparing the location of the selection tool to the location of the potential source of error; and determining an error when the location of the selection tool overlays the location of the potential source of error.