Abstract: The invention relates to a catheter having a single-layer inner tube, the single-layer inner tube with an inner surface forming a lumen and with an outer surface forming an outer surface of catheter duct, it being possible to arrange one or more guide wires in the lumen of the inner tube, characterized in that the single-layer inner tube is made of a material including: a) 96 to 99.9% by weight of a polymer, a copolymer, and/or a mixture of several polymers and/or copolymers; b) 0 to 1% by weight talc; c) 0 to 1% by weight calcium carbonate; d) 0 to 1% silicon dioxide; e) 0 to 1% by weight waxes; wherein the sum of the weight percentages of constituents b) to e) is at least 0.1% by weight, and no more than 4% by weight, and wherein all weight percentage information relates to the total weight of the single-layer inner tube.

Abstract: The invention relates to a drug-coated balloon catheter and to a method for producing the same. The balloon of the catheter includes (i) a main membrane, and (ii) an asymmetrical polymer membrane which is applied to an outside of the main membrane and into which at least one pharmaceutical active ingredient is introduced.

Abstract: The invention relates to intraluminal endoprosthesis, preferably a stent consisting essentially of a base body and optionally a coating covering the surface of the base body at least partially. The invention is characterized in that the base body and/or the coating has at least one compound from the group of polyphosphates, magnesium oxyhalides, preferably Sorel cement. Furthermore, a method is described for manufacturing such an intraluminal endoprosthesis.

Abstract: An application system for a stent comprising a catheter having at least one retention structure permanently connected to the catheter and a stent drawn onto the catheter using at least one retention element. The retention structure provides a retention area which receives and fixes the retention element. The retention element of the stent and the retention structure of the catheter have their geometry and position tailored to one another in such a way that the retention element is located in the retention area of the retention structure in the non-expanded state of the stent and the retention structure and/or the retention element are offset to one another upon expansion of the stent or at least in the expanded state of the stent so that the retention element is no longer located in the retention area of the retention structure.

Abstract: An implant is proposed, in particular made from a base material including a biodegradable metal and/or a biodegradable metal alloy, wherein the implant includes a coating made of crystalline calcium phosphate and/or amorphous calcium phosphate.

Abstract: The present invention relates to a measuring device including a sensor catheter, an evaluation unit, and means for receiving a magnetic field and converting the magnetic field to an electrical measurement signal which are situated in the sensor catheter and connected to the evaluation unit. The evaluation unit is designed to evaluate the electrical measurement signal.

Abstract: The present invention proposes an implant, in particular an intraluminal endoprosthesis, having a body, comprising at least one at least largely biodegradable metallic material, in particular magnesium or a magnesium alloy. To improve the degradation behavior, the implant has a first layer on at least a portion of its body surface, said layer containing a hydrogen-binding material, preferably palladium. Furthermore, methods for producing such an implant are given.

Abstract: The invention relates to a device, in particular for medical use as an endoprosthesis, preferably as an intraluminal endoprosthesis, having a base body (1, 1?), comprising at least partially a metallic material, and having a function element (3, 3?) that is attached to the base body and has a different metallic material composition in comparison with the material of the base body (1, 1?) in at least a portion of its volume, preferably having at least partially radiopaque and/or radiologically opaque material.

Abstract: The invention relates to a stent with a structure of a biocorrodible magnesium alloy or tungsten alloy, which comprises a multiplicity of web sections connected to one another, wherein (i) the structure has a support structure of a number of first web sections connected to one another, which are designed to perform a function supporting the vascular wall or preserving the mechanical integrity of the stent after an expansion of the stent for a predetermined period of time and (ii) at least one second web section is present, which a) is directly connected to a selected first web section, b) does not perform a function supporting the vascular wall or preserving the mechanical integrity of the stent after the expansion of the stent for the predetermined period of time, and c) has a smaller average grain size than the first web sections of the support structure from (i).

Abstract: The present invention relates to a medical product that can be implanted or introduced into a vascular system of a human or animal organism, having an active substance coating according to the invention on the surface of the medical product, to a method for the production of a medical product that can be implanted or introduced into a vascular system of a human or animal organism, having an active substance coating according to the invention, to an active substance coating according to the invention for a medical product that can be implanted or introduced into a vascular system of a human or animal organism, to uses of the active substance coating according to the invention for the production of a medical product that can be implanted or introduced into a vascular system of a human or animal organism, and to a method for treatment of a stenosis, etc., in the vascular system of a human or animal organism.

Abstract: The invention relates to a method for the production of at least one longitudinal section of a catheter, wherein the method comprises the winding of film, and the film is provided in the form of strips, the film strip is wound in the manner of a screw such that the side edges of the film strip extending in the manner of a thread overlap the film strip, and further a bonded connection is created in the overlapping region such that the longitudinal section has a closed and at least fluid-tight surface. The invention further relates to a catheter produced according to the method, and a device for carrying out the method.

Abstract: The present invention concerns medical products that release pharmaceutically active substances, the efficiency of which is increased as the result of a combination with an inhibitor of the transport protein P-glycoprotein.

Abstract: A method of treating a patient includes the medical use of one or more of the elements from the group yttrium, neodymium and zirconium, pharmaceutical formulations which contain said elements and implants which are at least region-wise made up of such formulations. It has been found inter alia that a formulation containing one or more of the elements has an action of inhibiting the proliferation of human smooth muscle cells.

Abstract: The invention relates to an endoprosthesis, in particular an intraluminal endoprosthesis, for example a stent, having a base body composed at least partially of a metallic material, and having a functional element which is attached to the base body or imbedded therein and which contains material that is radiopaque and/or X-ray opaque and has a different material composition, at least in a portion of its volume, compared to the material of the base body. To avoid contact corrosion and undesired corrosion, the functional element is provided with a barrier layer which electrically insulates the radiopaque and/or X-ray opaque material from the base body.

Abstract: The invention relates to an implant made of a biocorrodable metallic material and having a coating composed of or containing a biocorrodable polyphosphate, polyphosphonate, or polyphosphite.

Abstract: A catheter guide wire, especially for percutaneous transluminal coronary angioplasty, comprises an elongated wire shaft of a flexible material having a proximal and a distal end and disposed on the wire shaft at least one radiopaque, sleeve-like marker adjacent to the distal end. The at least one marker is disposed on a core section of the wire shaft, said core section being widened in its diameter relative to the diameter of the adjoining shaft sections.

Abstract: The present invention proposes a method for manufacturing an implant, in particular an intraluminal endoprosthesis, having a body such that the body has metallic material. To control the degradation in a desired time window, e.g., between four weeks and six months, the following production method is performed: a) preparing the body of the implant, and b) plasma-chemical treatment of at least a portion of the surface of the body in an aqueous solution by applying a plasma-generating electric alternating voltage to the body (5) of the implant, said voltage having a frequency of at least approximately 1 kHz, to create a first layer. The invention also relates to an implant obtainable by such a method.

Abstract: A method for manufacturing a degradation-inhibiting first layer on the surface of an implant body, in particular an intraluminal endoprosthesis, whereby the body has at least one metallic material, which is at least largely biodegradable, comprising the following steps: preparing the body of the implant, and applying the first layer to at least a portion of the body surface, whereby the first layer contains magnesium stearate. An implant obtainable by such a method.

Abstract: The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, with a body containing metallic material, preferably iron. To control the degradation of the implant, the method comprises the following steps: a) preparing the body of the implant, and b) incorporating hydrogen into at least a portion of the structure of the implant body near the surface. Furthermore, such an implant is described.

Abstract: An implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0-6.0% by weight, Nd: 1.5-4.5% by weight, Gd: 0-4.0% by weight, Dy: 0-4.0% by weight. Er: 0-4.0% by weight, Zr: 0.1-1.0% by weight, Li:0-0.2% by weight, Al: 0-0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5-4.0% by weight and b) a total content of Nd, Er, Gd and Dy is in the range of 2.0-5.5% by weight, the balance being magnesium and incidental impurities up to a total of 0.3% by weight.