Patents Assigned to Board of Trustees, Michigan State University
  • Patent number: 11485554
    Abstract: The disclosed articles, apparatus, methods, and compositions provide for the integration of different and environmentally-friendly processes for extraction, stabilization, and formulation of active compounds with health and/or other benefits from lignocellulosic by-products of food processes. The active compounds can include one or more of polyphenols, flavonoids, o-diphenols, anthocyanins, and phenolic acids. A high-pressure, high-temperature extraction process provides a means to recover a substantial portion of the active compounds from a biomass feedstock. The corresponding extract can be encapsulated, which provides a convenient form for stabilization and delivery of the active compounds into a final product, for example an active packaging material or corresponding actively packaged food item.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: November 1, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Bahar Aliakbarian, Mojgan Nejad
  • Patent number: 11474105
    Abstract: The present invention provides a method of diagnosing endometriosis and/or infertility in a subject, comprising: a) obtaining a sample from the subject; b) detecting a level of expression of a SIRT1 gene and/or protein in the sample; c) detecting a level of expression of a BCL6 gene and/or protein in the sample; d) comparing the level of expression detected in (b) with the level of expression of a SIRT1 gene and/or protein in a sample obtained from a control subject or a population of control subjects; e) comparing the level of expression detected in (c) with the level of expression of a BCL6 gene and/or protein in a sample obtained from a control subject or a population of control subjects; and f) diagnosing the subject as having infertility when the subject has a level of expression of the SIRT1 gene and/or protein greater than the level of expression of the SIRT1 gene and/or protein of the control subject or population of control subjects and also has a level of expression of the BCL6 gene and/or protein t
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: October 18, 2022
    Assignees: The University of North Carolina at Chapel Hill, Upstate Affiliate Organization, Board of Trustees of Michigan State University
    Inventors: Steven L. Young, Bruce Arthur Lessey, Jae Wook Jeong
  • Publication number: 20220326069
    Abstract: A system, apparatus, and method for demodulation of a fiber optic sensor is provided. An aspect of the system provides an optical fiber, a laser, a phase modulator configured to be coupled to the optical fiber, and a sensor. The laser emits a laser beam into the optical fiber. The phase modulator receives the laser beam from the laser and directs the laser beam to the sensor. The sensor includes a coiled portion of the optical fiber, uncoiled segments adjacent the coiled portion, and at least two fiber Bragg gratings configured to be coupled to opposite uncoiled segments adjacent the coiled portion of the optical fiber. The sensor system may further include a photodetector configured to receive a reflected portion of the laser beam from the sensor. The reflected portion is divided into at least two paths where at least two sub-outputs are generated for demodulation and sensing.
    Type: Application
    Filed: March 23, 2022
    Publication date: October 13, 2022
    Applicant: Board of Trustees of Michigan State University
    Inventor: Ming HAN
  • Publication number: 20220316439
    Abstract: A power generator or sensor apparatus is provided. Another aspect employs a hybrid triboelectric and electromagnetic generator. In still another aspect, a power generator is used for water wave energy harvesting. A further aspect provides a power generator including an outer housing with an electrical conductor on an exterior thereof, radial overlapping electrodes located within the housing with a dielectric layer between the electrodes, a plate linearly moveable within the housing, at least one magnet affixed to the plate, and at least one spring biasing the plate within the housing. Moreover, an aspect of the present power generator includes a modularized connection configuration to linearly secure together multiples of the housing.
    Type: Application
    Filed: March 29, 2022
    Publication date: October 6, 2022
    Applicant: Board of Trustees of Michigan State University
    Inventors: Changyong CAO, Yaokun PANG
  • Patent number: 11459579
    Abstract: Methods and compositions of improving plant yield by introducing into a plant the K-domain of a MADS box gene are disclosed. The expression of the K-domain provides plants with altered flower development, plant size and leaf development.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: October 4, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Guo-qing Song, Aaron Walworth, Dongyan Zhao
  • Patent number: 11452764
    Abstract: Methods and compositions are described herein that inhibit FAK/ATK interactions. Such methods and compositions are useful for inhibiting cell adhesion and cancer metastasis.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: September 27, 2022
    Assignees: University of North Dakota, Board of Trustees of Michigan State University
    Inventors: Marc D. Basson, Leslie A. Kuhn, Sebastian Raschka
  • Patent number: 11456902
    Abstract: A packet position modulation system includes a node configured to transmit a plurality of packets at corresponding time intervals. The node is configured to adjust, for at least one packet of the plurality of packets, the corresponding time interval to transmit the at least one packet. The system includes a base station configured to receive the plurality of packets from the node at corresponding time intervals, determine a difference between a previous time that a previous packet of the plurality of packets was received and a present time that a present packet of the plurality of packets was received, and recover coded data from the present packet based on the difference.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: September 27, 2022
    Assignee: Board of Trustees of Michigan State University
    Inventors: Subir K. Biswas, Dezhi Feng, Saptarshi Das
  • Patent number: 11447151
    Abstract: Advanced automotive active-safety systems, in general, and autonomous vehicles, in particular, rely heavily on visual data to classify and localize objects, most notably pedestrians and other nearby cars, to assist the corresponding vehicles maneuver safely in their environment. However, the performance of object detection methods is anticipated to degrade under challenging rainy conditions. Nevertheless, and despite major advancements in the development of deraining approaches, the impact of rain on object detection has largely been understudied, especially in the context of autonomous systems. This disclosure analyzes this problem space and presents an improved system for detecting objects under rainy conditions.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: September 20, 2022
    Assignees: Board of Trustees of Michigan State University, Ford Global Technologies, LLC
    Inventors: Hayder Radha, Mazin Hnewa, Jon Diedrich, Mark Gehrke
  • Publication number: 20220291054
    Abstract: A wirelessly powered resistive sensor is presented. The sensor includes: an antenna; a parametric resonator and a resistive loop circuit. The parametric resonator is configured to receive a pumping signal from the antenna and operable to oscillate at two frequencies. The resistive loop circuit is inductively coupled to the parametric resonator, such that oscillation frequency of the parametric resonator changes (e.g., linearly) with changes in resistance of the resistance loop circuit. The resistance of the resistor in the resistive loop circuit approximately equals the impedance of the resistive loop circuit at one resonance frequency of the parametric resonator. The resistive sensor may further include a resonator enhancer circuit arranged adjacent to the parametric resonator and operates to resonate at frequency of the pumping signal.
    Type: Application
    Filed: March 14, 2022
    Publication date: September 15, 2022
    Applicant: Board of Trustees of Michigan State University
    Inventors: Chunqi QIAN, Wei QIAN
  • Patent number: 11440999
    Abstract: A method is provided for pretreating cellulosic or lignocellulosic biomass comprising de-esterifying the biomass with an alkali treatment to produce de-esterified biomass; and pretreating the de-esterified biomass with ammonia to produce de-esterified ammonia pretreated biomass. In various embodiments, the de-esterified ammonia pretreated biomass has an amide concentration ranging from about 0.04 to about 25 mg/g biomass. In other embodiments, the amide concentration is no more than 0.04 mg/g biomass. Various ammonia pretreatment processes may be used, including liquid or gaseous ammonia pretreatments, including, but not limited to, liquid ammonium hydroxide pretreatments, various AFEX pretreatments, with or without biomass densification, and various cellulosic conversion pretreatments including “COBRA” pretreatments. Products (e.g., animal feed) and systems are also disclosed.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: September 13, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Venkatesh Balan, Leonardo da Costa Sousa
  • Patent number: 11440868
    Abstract: The disclosure relates to a reversible adhesive composition including a copolymer between a vinyl spacer monomer unit and a vinyl reversible binder monomer unit. Each monomer unit can be based on acrylate monomer, a vinyl ester monomer, or a vinyl ether monomer, with the spacer monomer unit generally having a shorter pendant chain (such as 1-3 carbon atoms) and the reversible binder monomer unit having a longer pendant chain (such as 3-20 carbon atoms). A corresponding article includes first and second surfaces (or substrates) that are in contact with and bonded to the reversible adhesive composition at an interface therebetween. The reversible adhesive composition generally involves non-covalent and/or non-ionic bonding forces, for example H-bonding, permanent dipole, electron donor-acceptor moieties, and/or van der Waals forces, between the copolymer chains.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: September 13, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventor: Muhammad Rabnawaz
  • Patent number: 11434501
    Abstract: This invention relates to the prevention and treatment of neurodegenerative diseases by administering compositions that increase the activity of a small proline-rich repeat 1 A protein (Sprr1A), or derivative thereof to the brain. Specifically, the compositions may comprise a nucleic acid molecule encoding a Sprr1A protein or a biologically-active portion thereof. The neurodegenerative disease may be Parkinson's Disease, Alzheimer's disease, amyotrophic lateral sclerosis, or traumatic brain injury.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: September 6, 2022
    Assignee: Board of Trustees of Michigan State University
    Inventors: Jack W. Lipton, Nicholas Kanaan, Timothy Collier
  • Publication number: 20220270268
    Abstract: Accurate vehicle localization is arguably the most critical and fundamental task for autonomous vehicle navigation. While dense 3D point-cloud-based maps enable precise localization, they impose significant storage and transmission burdens when used in city-scale environments. A highly compressed representation for LiDAR maps, along with an efficient and robust real-time alignment algorithm for on-vehicle LiDAR scans, is proposed here. The proposed mapping framework, requires less than 0.1% of the storage space of the original 3D point cloud map. In essence, mapping framework emulates an original map through feature likelihood functions. In particular, the mapping framework models planar, pole and curb features. These three feature classes are long-term stable, distinct and common among vehicular roadways. Multiclass feature points are extracted from LiDAR scans through feature detection.
    Type: Application
    Filed: July 29, 2020
    Publication date: August 25, 2022
    Applicant: Board of Trustees of Michigan State University
    Inventors: Hayder RADHA, Daniel MORRIS, Su PANG
  • Patent number: 11424770
    Abstract: Different techniques are presented for achieving enhanced linearity of digital transmitters. In one aspect, each unit cell of a switched capacitor circuit includes a capacitor electrically coupled via a switch to one of a drive voltage or a reference voltage, and the switch is implemented by two transistors coupled in series. The two transistors are transitioned between on and off states by control signals applied to control terminals of the two transistors, such that the control signals are pulse waves with edges temporally shifted in relation to each other and thereby reducing switching resistance during switch transitions.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: August 23, 2022
    Assignee: Board of Trustees of Michigan State University
    Inventors: Sangmin Yoo, Si-Wook Yoo
  • Publication number: 20220256123
    Abstract: A two-dimensional image of a vehicle occupant in a vehicle is collected. The collected two-dimensional image is input to a machine learning program trained to output one or more reference points of the vehicle occupant, each reference point being a landmark of the vehicle occupant. One or more reference points of the vehicle occupant in the two-dimensional image is output from the machine learning program. A location of the vehicle occupant in an interior of the vehicle is determined based on the one or more reference points. A vehicle component is actuated based on the determined location. For each of the one or more reference points, a similarity measure is determined between the reference point and a three-dimensional reference point, the similarity measure based on a distance between the reference point and the three-dimensional reference point.
    Type: Application
    Filed: February 9, 2021
    Publication date: August 11, 2022
    Applicants: Ford Global Technologies, LLC, Board of Trustees of Michigan State University
    Inventors: Robert Parenti, Adil Siddiqui, Mahmoud Yousef Ghannam, Yasodekshna Boddeti
  • Patent number: 11408329
    Abstract: An engine system employs a pre-assembled and/or removable cartridge. In another aspect, an ignitor, a fuel injector and an air inlet valve are all accessible from a top of a cartridge even after assembly of the cartridge to an engine cylinder head. A further aspect positions centerlines of an ignitor, a fuel injector and an air inlet valve angularly offset from each other and also angularly offset from a vertical centerline of a cartridge to which they are mounted.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: August 9, 2022
    Assignee: Board of Trustees of Michigan State University
    Inventors: Harold J. Schock, Thomas R. Stuecken
  • Patent number: 11396574
    Abstract: The disclosure relates to a self-healing omniphobic composition including a self-healing omniphobic polymer with a crosslinked backbone. The crosslinked backbone includes a reaction product between a polyisocyanate, a functionalized omniphobic polymer reactive therewith, a reversible polyfunctional linker including a hindered secondary amino group and/or an aromatic hydroxy group, and one or more polymeric backbone components. The crosslinked backbone includes reversible urea or reversible urethane bonds between the reversible polyfunctional linker and the polyisocyanate, which in turn provide self-healing properties to the omni-phobic composition. The self-healing omniphobic composition has favorable omniphobic properties, for example as characterized by water and/or oil contact and/or sliding angles. The omniphobic composition can be used as a coating on any of a variety of substrates to provide self-healing omniphobic properties to a surface of the substrate.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: July 26, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Muhammad Rabnawaz, Ajmir Khan, Kun Huang
  • Patent number: 11390834
    Abstract: The disclosure relates to a reactive distillation method for beverage spirit production, the method comprising. An initial reaction mixture includes water, ethanol, and a carboxylic acid, for example having 3 or more carbon atoms. The reaction mixture is reactively distilled in the presence of an esterification catalyst to react a portion of the ethanol and the carboxylic acid to form an ethyl carboxylate reaction product, and form a distillation product or distillate including water, ethanol, and the ethyl carboxylate. The esterification catalyst is not present in the distillation product, for example when using a solid acid esterification catalyst in the reaction mixture. In a refinement, ethanol and the carboxylic acid can be co-fermented in an initial grain mixture, which is subsequently reactively distilled according to the disclosed method.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: July 19, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Kris A. Berglund, Jacob Rochte
  • Patent number: PP34682
    Abstract: A new cherry tree variety suitable for use as rootstock.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: October 25, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventor: Amy Iezzoni
  • Patent number: PP34683
    Abstract: A new cherry tree variety suitable for use as rootstock.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: October 25, 2022
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventor: Amy Iezzoni