Patents Assigned to Board of Trustees, Michigan State University
  • Patent number: 10421975
    Abstract: The application describes plants, plant cells, and seeds that express WRINKLED1 transcription factors and/or 14-3-3 proteins that are useful for increasing production of oils in plants and seeds. Also described are expression systems and cassettes that encode and express such WRINKLED1 transcription factors and/or 14-3-3 proteins.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: September 24, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Christoph Benning, John B. Ohlrogge, Wei Ma, Que Kong
  • Publication number: 20190282110
    Abstract: An implantable device is provided. The implantable device includes a flexible polymeric substrate that extends through an aperture in an electrically conductive material to form an anchor that partially covers the electrically conductive material. Methods for fabricating the implantable device are also provided.
    Type: Application
    Filed: May 26, 2017
    Publication date: September 19, 2019
    Applicants: Board of Trustees of Michigan State University, Fraunhofer USA
    Inventors: Wen LI, Bin FAN, Robert RECHENBERG, Michael BECKER, Cory RUSINEK
  • Patent number: 10418991
    Abstract: A gating grid driver for use with radiation detectors, such as time projection chambers and other similar devices that require a gating grid that operates in a bipolar mode with different electrostatic potentials on alternating wires. To open such gating grids, the driver shorts the alternate wires to a common voltage Va. Later, this driver closes the grid by restoring the voltage differences in the adjacent wires. By connecting the driver circuit to the gating grid via low impedance transmission lines, the driver circuit opens the gating grid in 0.35 ?s, minimizing the lost drift length associated with this opening time. The circuit consists of 2 pairs of N- and P-MOSFET switches and includes two adjustable capacitors and resistors that can be used to adjust the opening time, and shift the balance of positive and negative charge for individual radiation detector.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: September 17, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Suwat Tangwancharoen, ManYee Betty Tsang, William G. Lynch
  • Patent number: 10420167
    Abstract: Techniques for sharing a cellular network connection amongst multiple devices over a local area network are provided that reduce cellular network load during crowded events. In an aspect, a devices is configure to perform operations that include scanning an area for another device that has established a first wireless cellular connection with a cellular network device of a cellular network and that enables an indirect connection of the device to the cellular network device via a direct connection of the device to the other device via a local network device. The operations further include, in response to identifying the other device as a result of the scanning, sending a request to the other device to connect to the other device via the local network device and to receive the indirect connection to the cellular network device.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: September 17, 2019
    Assignees: AT&T INTELLECTUAL PROPERTY I, L.P., BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Lusheng Ji, Jeffrey Pang, Jia Wang, Shobha Venkataraman, Muhammad Zubair Shafiq, Xiang-Yang Alex Liu
  • Patent number: 10408951
    Abstract: A radiation detector is provided. In a further aspect, a detector employs a Parallel Plate Avalanche Counter (“OPPAC”) which includes an anode film, a parallel cathode film and multiple optical photo-detectors, such as photo-sensors and/or photo-multipliers. A method of using a radiation detector is also provided.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: September 10, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Marco Cortesi, John E. Yurkon
  • Patent number: 10400813
    Abstract: A hybrid fastener is provided in combination with a structural insert. The insert is disposed about a shank of the fastener at an unthreaded section. In another aspect, a sleeve surrounds the shank of the fastener and has apertures for receiving the insert therethrough. Methods of using the above-described hybrid fastener for securing workpieces are also disclosed.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: September 3, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventor: Gary L. Cloud
  • Patent number: 10398323
    Abstract: A method is provided for determining pulse transit time of a subject as a function of blood pressure. The method includes: measuring a proximal waveform indicative of the arterial pulse at a proximal site of the subject; measuring a distal waveform indicative of the arterial pulse at a distal site of the subject; defining a relationship between the proximal waveform and the distal waveform in terms of unknown parameters of a nonlinear model; determining the unknown parameters of the nonlinear model from the measured proximal waveform and the measured distal waveform; and determining pulse transit time for the subject as a function of blood pressure from the parameters of the nonlinear model. The nonlinear model can account for arterial compliance and peripheral wave reflection, where the arterial compliance depends on blood pressure.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: September 3, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Ramakrishna Mukkamala, Mingwu Gao
  • Patent number: 10398324
    Abstract: A system and method is presented for cuff-less blood pressure measurement in a mobile device. A key aspect of this disclosure is the discovery of a new location for blood pressure measurement at the fingertip of a subject and that reflectance-mode photoplethysmography can be used to help make this measurement. Through experiments in human subjects, it was discovered that it is indeed possible to measure systemic blood pressure by having a subject press the fingertip against a reflectance-mode photo-plethysmography-force sensor unit under visual guidance and then compute blood pressure from the resulting variable-amplitude blood volume oscillations and applied pressure via an oscillometric algorithm.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: September 3, 2019
    Assignees: Board of Trustees of Michigan State University, University of Maryland, College Park
    Inventors: Ramakrishna Mukkamala, Anand Chandrasekhar, Jin-Oh Hahn
  • Patent number: 10392629
    Abstract: As described herein, plants expressing algal Diacylglycerol Acyltransferase Type Two (DGTT) from heterologous nucleic acids can alter acyl carbon partitioning in plant vegetative tissues and increase acyl-CoA-dependent triacylglycerol synthesis, thereby increasing the lipid content of the plants' tissues.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: August 27, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Christoph Benning, Sanjaya, Rachel Miller
  • Patent number: 10388975
    Abstract: Various embodiments relate to a method comprising forming a template from a template precursor, wherein the template contains an entrapped ceramic precursor, which can be further processed to form a ceramic solid, such as an oxide ceramic solid. In one embodiment, the template precursor is a hydrogel precursor and the template is a hydrogel template. The hydrogel template can include, for example, agarose, chitosan, alginate or a photo-initiating receptive hydrogel template such as a functionalized poly(ethylene glycol). Various devices, including electrolyte interfaces and energy storage devices, as well as thermoelectric devices are also provided. In one embodiment, the oxide ceramic solid is a cubic garnet having a nominal formula of Li7La3Zr2O12 (LLZO).
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: August 20, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Jeffrey Sakamoto, Travis Thompson, Ezhiyl Rangasamy, Daniel A. Lynam
  • Patent number: 10359378
    Abstract: In one aspect, the disclosure relates to a nuclear magnetic resonance transceiver including: (a) a variable-frequency electromagnetic signal generator with (i) a frequency input and (ii) an EM signal output; (b) an electronic frequency controller including (i) a frequency output coupled to the frequency input of the variable-frequency EM signal generator, (ii) an intermediate frequency set-point input, and (iii) an intermediate frequency measurement input; (c) an NMR transmission probe with an EM signal input coupled to the EM signal output of the variable-frequency EM signal generator; (d) an NMR receiving probe with an EM signal output; and (e) an electronic mixer with (i) a first input coupled to the EM signal output of the NMR receiving probe, (ii) a second input coupled to the EM signal output of the variable-frequency EM signal generator, and (iii) a mixed EM signal output coupled to the frequency measurement input of the frequency controller.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: July 23, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Evangelyn C. Alocilja, Yilun Luo
  • Patent number: 10349838
    Abstract: Methods are presented for determining pulse transit time (PTT) and/or pulse wave velocity (PWV) of a subject by application of parametric system identification to proximal and distal arterial waveforms. The two waveforms are measured from the subject. A system is defined that relates the proximal arterial waveform to the distal arterial waveform (or vice versa) in terms of the unknown parameters of a parametric mathematical model. The model parameters are determined from the measured waveforms using system identification. PTT between the proximal and distal arterial sites is then determined from the system model. PWV may also be determined by dividing the distance between measurement sites (D) by PTT.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: July 16, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Ramakrishna Mukkamala, Da Xu, Guanqun Zhang, Mingwu Gao, Mohsen Moslehpour
  • Patent number: 10343279
    Abstract: The Developmental Network incorporates a Turing Machine that injects teaching instructions directly into the skull-closed network. The Developmental Network can also autonomously learn directly from the natural world without the need for a human to encode its input and output. The neural network so configured can be used as a controller for robotic and other computer control applications where the neural network is organized into plural X-Y-Z areas receiving signals from sensors and providing signals to effectors.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: July 9, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Juyang Weng, Zejia Zheng, Xie He
  • Patent number: 10330610
    Abstract: An imaging system images near-field objects with focused microwave or terahertz radiation. Multiple antennas emit microwave or terahertz radiation, such that the radiation varies in frequency over time, illuminates a near-field object, reflects from the near-field object, and travels to a passive aperture. For example, the passive aperture may comprise a dielectric lens or a parabolic reflector. The passive aperture focuses, onto a spatial region, the microwave or terahertz radiation that reflected from the near-field object. One or more antennas take measurements, in the spatial region, of the microwave or terahertz radiation that reflected from the near-field object. A computer calculates, based on the measurements, an image of the near-field object and depth information regarding the near-field object.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: June 25, 2019
    Assignees: Massachusetts Institute of Technology, Board of Trustees of Michigan State University
    Inventors: Gregory Charvat, Andrew Temme, Micha Feigin-Almon, Ramesh Raskar, Hisham Bedri
  • Patent number: 10327698
    Abstract: A wearable breathing sensor, such as a piezoelectric chest belt system, generates a breathing signal that is analyzed by a classifier to identify apnea patterns indicating that the subject has swallowed during breathing. These breathing signals are computer-analyzed to extract inferences regarding the subject's eating and drinking patterns and thereby provide useful data for monitoring food or beverage intake for remote health monitoring.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: June 25, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Subir Biswas, Bo Dong
  • Patent number: 10332616
    Abstract: Disclosed herein is a method of estimating the pose of a ligand in a receptor comprising identifying all possible atom pairs of protein-ligand complexes in a given configuration space for a system that comprises proteins; creating a first database and a second database; where the first database comprises associated pairwise distant dependent energies and where the second database comprises all probabilities that include how the atom pairs can combine; combining the first database with the second database via statistical mechanics to accurately estimate binding free energies as well as a pose of a ligand in a receptor; and selecting a protein-ligand complex for further study.
    Type: Grant
    Filed: April 30, 2016
    Date of Patent: June 25, 2019
    Assignees: Board of Trustees of Michigan State University, University of Florida Research Foundation, Inc.
    Inventors: Zheng Zheng, Kenneth M. Merz, Jr.
  • Patent number: 10323074
    Abstract: The disclosure features, among other things, polypeptides comprising a Cryptic polypeptide, a functional fragment thereof, or variants of any of the foregoing. Also featured are nucleic acids encoding the polypeptides, methods for producing of the polypeptides, and a variety of diagnostic and therapeutic applications in which the polypeptides are useful. For example, the polypeptides can be used to treat a subject having a condition associated with bone loss.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 18, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Erik Martinez-Hackert, Senem Aykul
  • Patent number: 10296988
    Abstract: An electric power system or power grid is optimized using a computer-implemented tool the represents in computer memory the optimization function and at least one constraint, which the processor operates upon using a linear programming solver algorithm. The constraints are represented in memory as data structures that include both real and reactive power terms, corresponding to at least one of a power flow model and a transmission line model. The transmission line model is represented using a piecewise linear representation. The power flow model may also include for each node in the power system a real power loss term representing transmission line loss allocated to that node.
    Type: Grant
    Filed: August 13, 2014
    Date of Patent: May 21, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventor: Joydeep Mitra
  • Patent number: PP30538
    Abstract: A new cherry tree variety suitable for use as rootstock.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: May 28, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventor: Amy Iezzoni
  • Patent number: PP30553
    Abstract: A new cherry tree variety suitable for use as rootstock.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: June 4, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventor: Amy Iezzoni