Patents Assigned to Board of Trustees, Michigan State University
  • Patent number: 10254250
    Abstract: A probe capable of inducing a rotating magnetic field to excite a conductive tube includes an array of magnetic field sensors to detect and characterize defects in the tube. The probe includes a circumferential coil assembly and an axial coil assembly both positioned to induce eddy currents in the conductive tube, such that the magnetic field sensors can detect defects in the tube, including defects extending circumferentially, axially, or any combination thereof, whether at the surface or sub-surface of the tube inner and outer walls.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: April 9, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Satish S. Udpa, Lalita Udpa, Chaofeng Ye
  • Patent number: 10246695
    Abstract: The present invention provides novels genes encoding methyl butenol (MBO) synthase, methyl butenol synthases and their use in methyl butenol production.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: April 2, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Dennis Gray, Thomas D Sharkey
  • Patent number: 10246786
    Abstract: An inexpensive, easily renewable bioelectronic device useful for bioreactors, biosensors, and biofuel cells includes an electrically conductive carbon electrode and a bioelectronic interface bonded to a surface of the electrically conductive carbon electrode, wherein the bioelectronic interface includes catalytically active material that is electrostatically bound directly or indirectly to the electrically conductive carbon electrode to facilitate easy removal upon a change in pH, thereby allowing easy regeneration of the bioelectronic interface.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: April 2, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Robert Mark Worden, Brian L. Hassler, Lawrence T. Drzal, IIsoon Lee
  • Patent number: 10249910
    Abstract: A rechargeable lithium-ion cell has a cell capacity and includes a positive electrode having a recharged potential and a negative electrode. The rechargeable lithium-ion cell also includes a charge-carrying electrolyte. The charge-carrying electrolyte includes a charge-carrying medium and a lithium salt. The rechargeable lithium-ion cell also includes a redox shuttle having the following structure.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: April 2, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Thomas F. Guarr, Mathew M. Gregory, Nicholas Robert Boersma, Robert Andrew Polik, Nicholas Mortimer
  • Publication number: 20190096627
    Abstract: An electron spectroscopy system and method are disclosed. In another aspect, an ultrabright and ultrafast angle-resolved electron spectroscopy system is provided. A further aspect of the present system employs an electron gun, a radio frequency cavity and multiple spectrometers. Yet another aspect uses spectrometers in an aligned manner to deflect and focus electrons emitted by the electron gun. Moreover, an ultrafast laser is coupled to an electron spectroscopy system. A bunch of monochromatic electrons have their energy compressed and reoriented in an additional aspect of the present system. A further aspect of the present electron spectroscopy system employs adaptive and/or adjustable optics to optimize both time and energy compression. Another aspect provides at least two RF lenses or cavities, one before a specimen and one after the specimen.
    Type: Application
    Filed: February 28, 2017
    Publication date: March 28, 2019
    Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventor: Chong-Yu RUAN
  • Publication number: 20190085334
    Abstract: A method of decreasing the production of a pro-inflammatory cytokine in an activated cell of myeloid lineage in a subject in need thereof is provided. The method includes increasing at least one of signaling lymphocytic activation molecule F7 (SLAMF7) expression, SLAMF7 activity, and SLAMF7 signaling in the activated cell of myeloid lineage.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 21, 2019
    Applicant: Board of Trustees of Michigan State University
    Inventors: Yasser A. Aldhamen, Patrick Thomas O'Connell
  • Patent number: 10232001
    Abstract: The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method. The selection method is based on the strain's capability of reestablishing an altered microbial community to normal and/or harboring at least one of four specific SNPs.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: March 19, 2019
    Assignees: BioGaia AB, Board of Trustees of Michigan State University
    Inventors: Eamonn Connolly, Robert Allen Britton, Laura Rae McCabe
  • Patent number: 10221827
    Abstract: An ionization detector that reduces the filtering effects of the ignition coil inductances by shorting an inductance of a primary winding of the ignition coil. The ionization detector includes a bias voltage source and an inductance control switch. The bias voltage source supplies electric voltage across an electric gap of a spark plug for detecting ionization within the combustion chamber. The inductance control switch is electrically parallel with a primary winding of an ignition coil and is operable to short an inductance of the primary winding.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: March 5, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Guoming G. Zhu, Kevin D. Moran
  • Patent number: 10217549
    Abstract: A voltage-controlled resistor is provided. The resistor structure includes first and second resistive elements each including a phase change material that changes resistance in response to a change in temperature of the phase change material. A heating element is arranged in thermal contact with the first and second resistive elements. A control circuit receives a selected input voltage and supplies power based on the selected input voltage to the heating element to heat the first and second resistive elements to a selected temperature. The first and second resistive elements, which are proximate to and electrically isolated from each other, have a selected resistance at the selected temperature. A feedback circuit senses a change in temperature of the first resistive element and adjusts power supplied to the heating element based on the change in temperature of the first resistive element to maintain a resistance of the second resistive element at the selected resistance.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: February 26, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Rafmag Cabrera-Pizarro, Nelson Sepulveda-Alancastro
  • Patent number: 10216015
    Abstract: An optical attenuator (104) includes a substrate (116), an attenuation layer (120), and a pair of electrodes (124). The substrate (116) is transparent with respect to a range of light wavelengths. The attenuation layer (120) is formed on the substrate (116) and includes a strongly-correlated material. An optical transmissivity of the strongly-correlated material is strongly correlated with a resistance of the strongly-correlated material, and the optical transmissivity as applied to the light wavelengths is variable. The pair of electrodes (124) is at least one of formed on and embedded within the attenuation layer (120). The pair of electrodes (124) is configured to provide an indication of the resistance of the attenuation layer (120).
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: February 26, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Nelson Sepulveda-Alancastro, Noraica Davila-Melendez, Emmanuelle J. Merced-Grafals
  • Patent number: 10207229
    Abstract: The disclosure relates to a process and related article for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: February 19, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Merlin L. Bruening, Gregory L. Baker, Somnath Bhattacharjee, Yiding Ma
  • Patent number: 10203325
    Abstract: The disclosure relates to metal nanoparticle compositions and their methods of formation and use, in particular gold nanoparticles (AuNP) and gold-coated magnetic nanoparticles. Compositions according to the disclosure include aqueous suspensions of metal nanoparticles that are stabilized with one or more carbohydrate capping agents and/or that are functionalized with one or more binding pair members for capture/detection of a target analyte. The nanoparticle suspensions are stable for extended periods and can be functionalized as desired at a later point in time, typically prior to use in an assay for the detection of a target biological analyte. The stable nanoparticle suspension can be formed by the aqueous reduction of oxidized metal precursors at non-acidic pH values in the presence of a carbohydrate-based capping agent such as dextrin or other oligosaccharides.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: February 12, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Evangelyn C. Alocilja, Hanna Miller
  • Patent number: 10202660
    Abstract: A method of increasing sugar yield in a bioproduct production process is provided comprising pretreating one or more size-adjusted lignocellulosic biomass (LCB) particles with a pretreatment, such as an ammonia pretreatment, wherein the one or more size-adjusted LCB particles form a substrate, with the one or more particles having an average particle size in at least one dimension greater than 5 mm.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: February 12, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Venkatesh Balan, Bruce E. Dale, Shuhaida Harun
  • Patent number: 10202614
    Abstract: Plants described herein have increased biomass and are more readily digested into fermentable sugars when the plants express increased levels of one or more types of CGR2 and/or CGR3 enzymes.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: February 12, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Federica Brandizzi, Curtis Wilkerson, Sang Jin Kim, Michael Held
  • Patent number: 10201165
    Abstract: The present invention describes methods and formulations for protecting plants against various pathogens, involving the use of Prunus maackii materials. In some embodiments the biopesticide formulation comprises of at least one flavonoid such as 3,5,7-trihydroxy-6-methoxyflavone, 3,5,7-trihydroxy-6-methoxyflavanone or 5,7-dihydroxy-8-methoxyflavanone. The invention further provides a method of making the biopesticide by extracting a Prunus species with a solvent and formulating the composition using adjuvants, and kits for application of the biopesticide.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: February 12, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventors: Raymond Hammerschmidt, Linzi Kaniszewski, Cory Outwater
  • Patent number: 10195594
    Abstract: The invention relates to a novel zeolite catalysts, methods of producing the zeolite catalysts and a methods of using such catalyst, including for production of BTEX with improved yield, product selectivity and reduced char production. The present invention relates to novel mesoporous zeolite catalysts, as well as methods of producing the same. The present invention also relates to methods of producing renewable aromatic hydrocarbons using such catalysts.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: February 5, 2019
    Assignees: The Coca-Cola Company, Board of Trustees of Michigan State University
    Inventors: Shantanu Kelkar, Thomas J. Pinnavaia, Christopher M. Saffron, Robert Kriegel
  • Patent number: 10193430
    Abstract: An electromagnetic device includes discrete wires for its poles or teeth. In another aspect, an electromagnetic device includes a stator unit and an adjacent movable unit, at least one of which includes magnetic flux-carrying poles, with a majority of each pole including multiple discrete wires. In another aspect, the movable unit is an electric motor rotor, a linear electric motor armature, a solenoid armature, or an electric generator rotor.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 29, 2019
    Assignee: Board of Trustees of Michigan State University
    Inventor: Norbert Müller
  • Publication number: 20190015353
    Abstract: The present invention relates to the administration of compositions comprising polyethylene glycol, for improving the general gastrointestinal health of an animal increasing growth performance and treating osteopenia, osteoporosis and other bone disorders.
    Type: Application
    Filed: August 10, 2018
    Publication date: January 17, 2019
    Applicants: MIDWAY PHARMACEUTICALS, INC., BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Rifat PAMUKCU, Laura Rae McCABE
  • Patent number: 10161296
    Abstract: An internal combustion engine includes a pre-chamber. In another aspect, pressure within a pre-chamber is equal to or greater than pressure within a main combustion chamber at least prior to ignition in the main combustion chamber. In yet another aspect, internal combustion engine control software automatically controls pressure within a turbulent jet ignition pre-chamber, controls a valve-actuator to admit a fuel-air charge into the pre-chamber, and causes an igniter to initiate combustion in the pressurized pre-chamber. This also permits the rate of combustion to be controlled in the primary chamber regardless of the air-fuel ratio or the diluent fraction in the main chamber. Another aspect employs a pre-chamber purge pump with separate air and fuel injection.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: December 25, 2018
    Assignee: Board of Trustees of Michigan State University
    Inventors: Harold Schock, Guoming Zhu, Elisa Toulson, Thomas Richard Stuecken
  • Patent number: 10160156
    Abstract: The disclosure relates to punch die apparatus, related thermoforming press apparatus, and methods for thermohydroforming die-punched parts formed therefrom, in particular from sheet blank substrates such as polymer composite materials and metals. The disclosure further relates to thermohydroforming blanks incorporating a vacuum-sealed outer film, in particular polymer composite blanks which can be used in combination with the disclosed apparatus. The apparatus and methods are particularly suitable for thermohydroforming parts with complex deep drawn geometries yet which retain relatively smooth outer surfaces and internal material structure. The apparatus and methods provide a fast and efficient means for composite part manufacturing.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: December 25, 2018
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Farhang Pourboghrat, Nicholas E. Kuuttila