Patents Assigned to Boehringer Ingelheim Pharma GmbH & Co. KG
  • Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
    Publication number: 20060057074
    Abstract: The present invention relates to novel pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics, processes for preparing them and their use in the treatment of respiratory diseases.
    Type: Application
    Filed: November 4, 2005
    Publication date: March 16, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Christopher Meade, Michel Pairet, Michael Pieper
  • Esters of hydroxyl-substituted nitrogen heterocycles, processes for the preparation thereof as well as the use thereof as pharmaceutical compositions
    Publication number: 20060058344
    Abstract: The present invention relates to new compounds of general formula 1 wherein X? and the groups A, B, R, R1, R2, R3, R3?, R4, R4?, Rx and Rx? may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharmaceutical compositions.
    Type: Application
    Filed: November 9, 2005
    Publication date: March 16, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Grauert, Michael Pieper, Gerald Pohl, Georg Speck, Steffen Breitfelder
  • New method for preparing tiotropium salts
    Publication number: 20060047120
    Abstract: The invention relates to a new process for preparing tiotropium salts of general formula 1 wherein X? may have the meanings given in the claims and in the specification.
    Type: Application
    Filed: August 23, 2005
    Publication date: March 2, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co., KG
    Inventors: Ralf Lock, Werner Belzer, Rainer Hamm, Monika Hofmann
  • Compounds for the reduction of excessive food intake
    Publication number: 20060030607
    Abstract: The invention relates to the use of dopamine receptor agonists for preparing a pharmaceutical composition for the reduction of excessive food intake.
    Type: Application
    Filed: October 6, 2005
    Publication date: February 9, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Michael Pieper, Joachim Mierau
  • Methods for treating diseases or conditions using dihydropteridinone compounds
    Publication number: 20060025411
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: September 6, 2005
    Publication date: February 2, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Hoffmann, Matthias Grauert, Martin Steegmaier, Anke Baum, Jens Quant, Flavio Solca, Florian Colbatzky
  • Process for manufacturing of chiral lobelin
    Publication number: 20060014791
    Abstract: The present invention relates to a shortened process for preparing L-lobeline by rhodium-catalysed asymmetric hydrogenation on an industrial scale.
    Type: Application
    Filed: July 8, 2005
    Publication date: January 19, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Franz-Dietrich Klingler, Rainer Sobotta
  • Process for isolating of alpha-mangostin
    Publication number: 20060014967
    Abstract: The invention relates to a process for obtaining and purifying pure ?-mangostin from the rind of the fruit (mangosteen) of Garcinia mangostana.
    Type: Application
    Filed: July 14, 2005
    Publication date: January 19, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Rainer Sobotta, Hans-Peter Ignatow
  • Process for manufacturing of enantiomerically pure 3-hydroxy-3-phenyl-propylamin
    Publication number: 20060009533
    Abstract: The present invention relates to an improved process for preparing enantiomerically pure 3-hydroxy-3-phenyl-propylamines on an industrial scale using asymmetrical hydrogenation as a key step and optionally a special sequence of subsequent steps, using a catalyst system consisting of rhodium and chiral 4-(dicyclohexylphosphino)-2-(diphenyl-phosphino-methyl)-N-methyl-aminocarbonyl-pyrrolidine.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 12, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Wolfgang Baumgarten, Robert Schiffers
  • Cyclopropane CGRP antagonists, medicaments containing these compounds, and method for the production thereof
    Publication number: 20050267137
    Abstract: A compound of general formula (I) wherein R and R1 are as defined herein, or a tautomer, diastereomer, enantiomer, or salt thereof, particularly the physiologically acceptable salts thereof, which have valuable pharmacological properties, particularly CGRP-antagonistic properties, pharmaceutical compositions containing the compound, their use, and processes for preparing them.
    Type: Application
    Filed: June 27, 2005
    Publication date: December 1, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Wolfgang Eberlein, Wolfhard Engel, Klaus Rudolf, Henri Doods, Gerhard Hallermayer, Eckhart Bauer
  • 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
    Publication number: 20050255119
    Abstract: The present invention relates to compositions, preferably powdered compositions such as spray-dried or freeze-dried powders, containing an antibody or and antibody derivative and one or more 1,4 O-linked saccharose derivatives chosen from the compounds: 1,4 O-linked D-gal-saccharose (lactosucrose), 1,4 O-linked D-glu-saccharose (glucosyl sucrose) or 1,4 O-linked glu-glu-saccharose (maltosyl sucrose). Preferred combinations are those which contain lactosucrose or a combination of glucosyl and maltosyl sucrose.
    Type: Application
    Filed: May 2, 2005
    Publication date: November 17, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Stefan Bassarab, Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Patrick Garidel, Torsten Schultz-Fademrecht
  • Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
    Publication number: 20050256193
    Abstract: The invention relates to the use of ambroxol and the pharmacologically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of painful conditions in the oral and pharyngeal cavity.
    Type: Application
    Filed: July 20, 2005
    Publication date: November 17, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Anke Esperester, Uwe Pschorn, Jean-Michel Vix
  • Powder comprising new compositions of oligosaccharides and methods for their preparation
    Publication number: 20050250704
    Abstract: The present invention concerns powders containing a pharmaceutical active substance and a combination of excipients comprising at least one 1,4 O-linked saccharose derivative selected from the compounds: 1,4 O-linked D-Gal-saccharose (lactosucrose), 1,4 O-linked D-Glu-saccharose (glucosyl sucrose), or 1,4 O-linked Glu-Glu-saccharose (maltosyl sucrose) in combination with at least one further excipient. The other excipient is preferably an amino acid, a peptide and/or a mono-, di- and/or oligosaccharide, wherein the oligosaccharide may be a second 1,4 O-linked saccharose derivative, provided that this is different from the first.
    Type: Application
    Filed: May 2, 2005
    Publication date: November 10, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Stefan Bassarab, Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Patrick Garidel, Torsten Schultz-Fademrecht
  • Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
    Publication number: 20050250705
    Abstract: The present invention relates to a spray-dried powder and method for its manufacture. A spray dried powder containing a pharmaceutical active substance and one or more 1,4 O-linked saccharose derivatives chosen from the compounds: 1,4 O-linked D-gal-saccharose (lactosucrose), 1,4 O-linked D-glu-saccharose (glucosyl sucrose) or 1,4 O-linked glu-glu-saccharose (maltosyl sucrose). Preferred combinations are such that they contain glucosyl and maltosyl sucrose.
    Type: Application
    Filed: May 2, 2005
    Publication date: November 10, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH Co. KG
    Inventors: Stefan Bassarab, Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Patrick Garidel, Torsten Schultz-Fademrecht
  • Betamimetics with a prolonged duration of activity, processes for preparing them, and their use as pharmaceutical compositions
    Publication number: 20050234134
    Abstract: A compound of formula 1 wherein: R1 is C1-C4-alkyl; R2 is C1-C4-alkyl; and R3 is C1-C4-alkyl or phenyl, each optionally mono- or polysubstituted, or R2 and R3 together are —CH2—CH2— or —CH2—CH2—CH2—, or the corresponding acid addition salt with a pharmacologically acceptable acid, processes for preparing such compounds, pharmaceutical compositions containing such compounds, and their use in the treatment of inflammatory and obstructive respiratory diseases.
    Type: Application
    Filed: June 6, 2005
    Publication date: October 20, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Buettner, Ingo Konetzki, Kurt Schromm, Hermann Schollenberger, Sabine Pestel, Andreas Schnapp, Thierry Bouyssou, Claudia Heine
  • Medicaments for the treatment of chronic obstructive pulmonary disease
    Publication number: 20050222144
    Abstract: A pharmaceutical composition comprising a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, C1-C4-alkyl, halogen, OH, or —O—C1-C4-alkyl; R2 is hydrogen, C1-C4-alkyl, halogen, OH, or —O—C1-C4-alkyl; R3 is hydrogen, C1-C4-alkyl, OH, halogen, —O—C1-C4-alkyl, —O—C1-C4-alkylene-COOH, or —O—C1-C4-alkylene-CO—O—C1-C4-alkyl, or an acid addition salt thereof with a pharmacologically acceptable acid, or a solvate or hydrate thereof; and a pharmaceutically acceptable excipient or carrier, and methods for using the pharmaceutical formulation in the treatment of chronic obstructive pulmonary disease (COPD).
    Type: Application
    Filed: May 18, 2005
    Publication date: October 6, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Ingo Konetzki, Kurt Schromm, Hermann Schollenberger, Sabine Pestel, Andreas Schnapp, Thierry Bouyssou, Frank Buettner, Claudia Heine, Philipp Lustenberger, Christoph Hoenke, Klaus Rudolf
  • Betamimetics with a prolonged duration of activity, processes for preparing them, and their use as pharmaceutical compositions
    Patent number: 6951888
    Abstract: A compound of formula 1 wherein: R1 is C1-C4-alkyl; R2 is C1-C4-alkyl; and R3 is C1-C4-alkyl or phenyl, each optionally mono- or polysubstituted, or R2 and R3 together are —CH2—CH2— or —CH2—CH2—CH2—, or the corresponding acid addition salt with a pharmacologically acceptable acid, processes for preparing such compounds, pharmaceutical compositions containing such compounds, and their use in the treatment of inflammatory and obstructive respiratory diseases.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: October 4, 2005
    Assignee: Boehringer Ingelheim Pharma Gmbh & Co. KG
    Inventors: Frank Buettner, Ingo Konetzki, Kurt Schromm, Hermann Schollenberger, Sabine Pestel, Andreas Schnapp, Thierry Bouyssou, Claudia Heine
  • Novel substituted piperidines, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof
    Publication number: 20050215546
    Abstract: The present invention relates to substituted piperidines of general formula wherein R, R2 to R5, A, X, Z and n are defined as in claim 1, the tautomers, diastereomers, enantiomers, mixtures and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, particularly CGRP-antagonistic properties, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.
    Type: Application
    Filed: May 26, 2005
    Publication date: September 29, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Rudolf Hurnaus, Klaus Rudolf, Stephan Mueller, Dirk Stenkamp, Phillipp Lustenberger, Alexander Dreyer, Kai Gerlach, Marcus Schindler, Kirsten Arndt, Eckhart Bauer
  • Process for obtaining betulinic acid
    Patent number: 6943260
    Abstract: The invention relates to an improved process for obtaining highly pure, crystalline betulinic acid from a methanolic extract of ground plane tree cortex and/or plane tree bark, as well as highly pure crystalline betulinic acid which is solvated with one equivalent of ethanol.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: September 13, 2005
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventor: Markus Sauter
  • Anticholinergics which may be used as medicaments as well as processes for preparing them
    Publication number: 20050197357
    Abstract: The present invention relates to new anticholinergics of general formula 1 wherein A, X?, and the groups R1, R2, R3, R4, R5, R6 and R7 may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharmaceutical compositions.
    Type: Application
    Filed: April 28, 2005
    Publication date: September 8, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Rolf Banholzer
  • Powders comprising low molecular dextran and methods of producing those powders
    Publication number: 20050191246
    Abstract: Disclosed are powders, preferably spray-dried powders, which contain a pharmaceutical active substance and low-molecular dextran as excipient. Also disclosed are processes for preparing such powders and methods of administering them by inhalation.
    Type: Application
    Filed: November 30, 2004
    Publication date: September 1, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Stefan Bassarab, Patrick Garidel, Torsten Schultz-Fademrecht