Abstract: Methods and systems for performing secure quantum key distribution (QKD) over noisy channels are disclosed. A first computing device generates a challenge set using a secret seed, applies the challenges to its CRP, and receives an ordered set n responses, where n has the same number of bits as the key. It then sends only those responses in positions that correspond to 1s in the key to the second computing device. Those responses are sent under a QKD protocol such as BB84. The second computing device generates the same challenges and recovers the same responses with a mirror CRP mechanism. It also receives the subset of responses from the first computing device. Generated responses that match received responses correspond to 1s in the key, and 0s are assigned to all other positions.
Type:
Grant
Filed:
October 6, 2024
Date of Patent:
September 8, 2026
Assignees:
ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY, BROWN UNIVERSITY
Inventors:
Bertrand F. Cambou, Jeffrey Hoffstein, Dina Ghanaimiandoab, Brit Riggs, Ian Burke, Julie B. Heynssens
Abstract: This invention relates to an aqueous composition comprising, (a) an ion-exchange resin (IXR) comprising microporous beads having a particle size ranging from about 200 um to about 1000 um; (b) a water soluble surfactant having a molecular weight ranging from about 7,500 to about 15,000 Da; and (c) a buffer component; wherein the pH of the aqueous composition ranges from about 5 to about 8, and a process for isolating chemical contaminants using the aqueous composition.
Abstract: Audio signals, collected with equipment commonly available to individuals (e.g., a mobile device), can be used to analyze a patient's breathing. An audio signal associated with the patient's breathing for a time period can be detected with the mobile device and used to approximate the patient's respiratory flow for the time period. For example, the audio signal can be analyzed by determining a representation of an audio frequency of the audio signal, splitting the audio frequency of the audio signal into distinct time steps, determining points comprising a weighted mean frequency at each time step, applying a frequency-to-flow rate linear transformation at each time step to approximate the respiratory flow versus time, and plotting a graphical representation of the respiratory flow versus time. The respiratory flow for the time period can be tagged with a factor related to the patient and saved in a database for future analysis.
Type:
Grant
Filed:
January 20, 2023
Date of Patent:
August 25, 2026
Assignee:
BROWN UNIVERSITY
Inventors:
Christopher M. Dodson, Rashid Zia, Christopher Rose
Abstract: Described herein are devices that relate to sensor, data, and interactive interfaces between micro or nano electronics and biofilms, which optionally include an added extracellular matrix. Biofilms in the interfaces can include adherent cells or microorganisms, for example, fungi, bacteria, and the biofilms may include viruses. Computational capability, circuitry, and methods are provided for interactive measurements/processing between the electronics and biofilms.
Type:
Grant
Filed:
April 13, 2023
Date of Patent:
August 18, 2026
Assignees:
Brown University, Trustees of Boston University
Inventors:
Jacob K. Rosenstein, Kangping Hu, Joseph W. Larkin
Abstract: A thermal accelerant can be used as a drug delivery vehicle to deliver one or more drugs to a target site. For example, in some embodiments, a carrier such as albumin or human serum albumin (HSA) can be impregnated with, or covalently attached to, an anti-tumor agent and delivered to a location proximate to a tumor of a patient. The carrier can be exposed to an energy source that structurally alters the carrier and releases the agent therefrom. The sources of energy can include one or more of microwave, radiofrequency, electrical pulse (electroporation) or sonar (HIFU or histotripsy). In some embodiments, the anti-tumor agent can be delayed release such that a portion of the agent is released from the carrier over an extended period of time. The incorporation of an anti-tumor agent in a thermal accelerant provides a thermal ablation-drug delivery combination therapy (e.g., a thermally-activated combination therapy).
Type:
Grant
Filed:
May 23, 2022
Date of Patent:
August 11, 2026
Assignees:
Rhode Island Hospital, Brown University
Inventors:
William Keun Chan Park, Damian E. Dupuy
Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.
Abstract: Aspects of the invention are associated with the discovery of processes for converting methane (CH4), present in a methane-containing feed that may be obtained from a variety of sources such as natural gas, to higher hydrocarbons (e.g., C2+ hydrocarbons) such as C2 hydrocarbons (e.g., ethane, ethylene, and acetylene) and aromatic hydrocarbons (e.g., benzene, one or more C1- or C2-substituted benzenes, and/or one or more fused ring aromatic hydrocarbons). Representative processes involve direct, non-oxidative methane conversion (NOMC), such that the need for an oxidant to form CO as an intermediate may advantageously be avoided. This reduces overall complexity and the tendency to promote unwanted side reactions that reduce hydrocarbon yields and lead to CO2 production.
Type:
Grant
Filed:
March 21, 2022
Date of Patent:
June 23, 2026
Assignees:
Brown University, SK Innovation Co., Ltd.
Inventors:
Andrew Peterson, Franklin Goldsmith, Jongyoon Bae, Dongmin Yun, Juhwan Im, Dokyoung Kim
Abstract: A method for scanning near-field optical microscopy comprises illuminating an apertureless atomic force microscopy (AFM) probe with electromagnetic energy having a frequency in the Terahertz range, where the sample under observation includes a dielectric layer having a thickness greater than the radius of the tip of the AFM probe. A system for scanning near-field optical microscopy comprises a collimated light source for emitting collimated light, a photoconductive antenna for converting collimated light into electromagnetic energy having a frequency in the Terahertz range, an AFM probe, a sample comprising a dielectric layer, the dielectric layer having a thickness greater than the radius of the probe tip; and a detector configured to detect energy that has interacted with the sample.
Abstract: A method of representing a space of handwriting stroke styles includes representing writer-, character- and writer-character-level style variations within a recurrent neural network (RNN) model using decoupled style descriptors (DSD) that model the style variations such that character style variations depend on writer style.
Type:
Grant
Filed:
August 23, 2021
Date of Patent:
June 9, 2026
Assignee:
Brown University
Inventors:
Atsunobu Kotani, Stefanie Tellex, James Tompkin
Abstract: Described herein are bispecific antibodies simultaneously targeting both CHI3L1 and the immune checkpoint molecule PD-1. These antibodies manifest enhanced synergistic cytotoxic effects compared to the effects of individual CHI3L1 and PD-1 antibodies, alone or in combination. Methods of treating a cancer by administering the bispecific antibodies described herein are also provided.
Type:
Grant
Filed:
May 6, 2020
Date of Patent:
June 9, 2026
Assignee:
Brown University
Inventors:
Jack A. Elias, Chun Geun Lee, Suchitra Kamle
Abstract: A complementary metal-oxide-semiconductor sensor array includes an active sensing area of pixels arranged in an array with a pitch, each pixel including an exposed surface electrode alongside switches and logic gates, and non-overlapping clocks configured to rapidly charge and discharge the exposed surface electrode, wherein control signals steer a switched output current between shared column outputs.
Abstract: Methods for the encoding an encryption key for secure storage are disclosed. The methods rely on the use of unclonable, one-way functions, such as images of biological objects that may be measured according to challenges to result in responses. A biometric print of a biological object is measured with a set of n challenges resulting in n responses. The responses are an ordered sequence, with each response having a fixed position in the sequence. A key is generated of bit length n. A subset of m responses in the full set of n responses is selected, where the selected responses correspond to positions of is in the key. The response subset is stored. The key is then used, and deleted. A party wishing to re-generate the key generates the same set of challenges, measures the same biological object with the challenges a second time, and generates a second set of n responses.
Type:
Grant
Filed:
April 17, 2024
Date of Patent:
May 12, 2026
Assignees:
ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY, BROWN UNIVERSITY
Abstract: A laminated structure is prepared by providing a self-assembled monolayer between an ETL and an MHP layer, wherein the self-assembled monolayer is formed by a monomer having the formula halide-alkyl linker-anchor moiety.
Abstract: A multi-frequency wireless access device including a first waveguide having a pair of parallel metal plates with open sides and a slot in one of the metal plates, the slot permitting radiation to leak out, the leaked radiation illuminating a range of angles depending on frequency.
Type:
Grant
Filed:
July 17, 2024
Date of Patent:
March 24, 2026
Assignees:
BROWN UNIVERSITY, William Marsh Rice University
Abstract: Systems and methods are provided for fabricating an assembly with a controllable magnetic state and ferromagnetic resonance. A layer of twisted bilayer graphene is positioned in contact with a transition metal dichalcogenide to form a structure with an interface between the twisted bilayer graphene and the transition metal dichalcogenide. Energy is applied to the interface to adjust one of a magnetic state associated with the interface and a ferromagnetic resonance associated with the interface.
Type:
Grant
Filed:
January 30, 2023
Date of Patent:
February 24, 2026
Assignees:
BROWN UNIVERSITY, NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC
Inventors:
Jia Li, Andrew Mounce, Erin Morissette, Jiangxiazi Lin
Abstract: High accuracy selections of grouped elements can be achieved using a brain machine interface. A neural decoding system can: receive a neural signal from a neural recording device, identify that the neural signal is representative of the user at least thinking of attempting to perform a gesture, which is one of a plurality of known gestures mapped to a plurality of commands, and output a command based on the gesture (the gesture is mapped to the command). A controller can be in communication with the neural decoding system and a display. The controller can: receive the command, if the gesture is a primary gesture, then select a group to be an active group of elements, if the gesture is a secondary gesture, then at least select an element of the active group of elements and output a response indicative of the group being activated and/or the element being selected.
Type:
Grant
Filed:
November 14, 2024
Date of Patent:
February 24, 2026
Assignees:
BROWN UNIVERSITY, THE GENERAL HOSPITAL CORPORATION, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
Inventors:
Leigh Hochberg, Stefan Eduardo Lütschg Espinosa, Thomas Hosman, David Rosler, John D. Simeral, Carlos Vargas-Irwin, Natalie Herrick
Abstract: Described herein are compositions and methods for treating P. falciparum malaria by specifically activating apoptosis in cells that express PfGARP without activating apoptosis in subject host cells or parasite cells that do not express PfGARP.
Type:
Grant
Filed:
February 28, 2022
Date of Patent:
February 10, 2026
Assignees:
BROWN UNIVERSITY, FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES
Inventors:
Jonathan Kurtis, Andrew V. Oleinikov, Dipak K. Raj
Abstract: Disclosed is a method for preventing, delaying or reversing age-associated inflammation, by administering to a patient in need thereof a therapeutically effective amount of at least one reverse transcriptase inhibitor (RTI).