Abstract: A dispenser for two liquids such as liquor and flavoring mounted on a bottle of the first liquid. A container of the second liquid is provided in the dispenser. When the bottle is tilted, a predetermined amount of both liquids are measured in separate measuring containers within the dispenser. When a trigger is pulled, the measured amounts of both liquids are released together so as to mix, while the release of both liquids beyond the measured amounts is blocked.

Abstract: A device for assembling aggregations of adherent cells includes a gripper moveable within an assembly vessel that fixes aggregations of adherent cells at a membrane of the gripper and, by movement of the gripper, assembles aggregations of cells on a separate membrane within the vessel, thereby creating a three-dimensional assembly of aggregations of cells that fuse and can be employed in surgical procedures as a unitary tissue of adherent cells. The aggregations of cells, as assembled, can assume three-dimensional configurations distinct from any one of the component aggregations of cells assembled.

Abstract: Methods and systems for producing a hydrocarbon are provided. The method can include cracking one or more C2-C10 hydrocarbons in the presence of a catalyst under conditions sufficient to produce an effluent containing ethylene, propylene, gasoline, and a coked-catalyst, wherein the catalyst includes a first catalytic component having an average pore size of less than 6.4 ? and a second catalytic component having an average pore size of 6.4 ? or more, separating the effluent to provide a recovered coked-catalyst and a cracked product; and regenerating the recovered coked-catalyst to produce heat and the catalyst.

Abstract: Disclosed are computer-readable devices, systems and methods for generating a model of a clothed body. The method includes generating a model of an unclothed human body, the model capturing a shape or a pose of the unclothed human body, determining two-dimensional contours associated with the model, and computing deformations by aligning a contour of a clothed human body with a contour of the unclothed human body. Based on the two-dimensional contours and the deformations, the method includes generating a first two-dimensional model of the unclothed human body, the first two-dimensional model factoring the deformations of the unclothed human body into one or more of a shape variation component, a viewpoint change, and a pose variation and learning an eigen-clothing model using principal component analysis applied to the deformations, wherein the eigen-clothing model classifies different types of clothing, to yield a second two-dimensional model of a clothed human body.

Abstract: Methods and systems for producing a hydrocarbon are provided. The method can include cracking one or more C2-C10 hydrocarbons in the presence of a catalyst under conditions sufficient to produce an effluent containing ethylene, propylene, gasoline, and a coked-catalyst, wherein the catalyst includes a first catalytic component having an average pore size of less than 6.4 ? and a second catalytic component having an average pore size of 6.4 ? or more, separating the effluent to provide a recovered coked-catalyst and a cracked product; and regenerating the recovered coked-catalyst to produce heat and the catalyst.

Abstract: An apparatus for a piezoelectric ink-jet printhead is disclosed. Piezoelectric printheads, while more expensive are favored because they use a wider variety of inks. The piezoelectric printhead includes a plurality of ink ejectors with a nozzle, an ink chamber, at least one body chamber, at least one diaphragm material, and a top electrode. The diaphragm material consists of a foil with built up piezoelectric material. The deflection of the diaphragm on the body chamber contributes to a pressure pulse that is used to eject a drop of liquid from the nozzle. According to an exemplary embodiment disclosed, a thin-film piezoelectric printhead uses existing low-cost adhesive based jet stack fabrication processed with polymers and metal foil layers and avoids the cost and complexity of a Micro-electrical-mechanical (MEMS) based fabrication system. According to another exemplary embodiment of this disclosure, provided is a thick hybrid film piezoelectric printhead.

Abstract: A system for cooling particulates includes a gasifier, a particulate cooler, an elongated shell, a shell side particulate inlet, a tube side fluid inlet, a tube bundle, a coolant outlet, one or more upper aeration nozzles, and one or more lower aeration nozzles. The tube bundle has a plurality of tubulars. The upper aeration nozzles are located within the shell and direct a first aeration gas toward the tube bundle and the lower aeration nozzles are disposed on a sidewall or a narrowing member or the shell and direct a second aeration gas toward a particulate outlet. A related method uses the described system.

Abstract: A system is provided for removing arsenic from water to safe levels at or below the EPA standards. The system is a hybrid spouted vessel/fixed bed filter system that significantly enhances/improves arsenic removal for drinking water using zero-valent iron (ZVI) particles. Movement of the circulating, iron-containing particles in a dense moving bed that forms on the spouted vessel bottom creates an abrasive “self-polishing” action among them that continuously generates colloidal iron corrosion products. This material then circulates with the water in the vessel and is removed and concentrated in a fixed bed filter. The colloidal material captured and immobilized in the filter has been shown to remove arsenic from contaminated water at very rapid rates.

Abstract: Methods and systems for removing volatile organic compounds from spent air are provided. The method can include oxidizing cumene in the presence of an oxidant to produce an oxidized product containing methanol and a spent air, separating the spent air from the oxidized product, contacting the spent air with an absorbent, an adsorbent, or a mixture thereof to remove at least a portion of any impurities in the spent air to produce a first purified air, and contacting the first purified air with a biological material to produce a treated air.

Abstract: Provided herein are compounds of Formula (I) or (II): (I) (II) pharmaceutically acceptable salts, tautomers, prodrugs, and stereoisomers thereof, and pharmaceutical compositions thereof, wherein X, RN, R1, R3, R4, p, and m are as defined herein. Such compounds and compositions have been found useful in the treatment or prevention of viral infections, e.g., polyomaviral infections, and are further envisioned useful in treatment or prevention of other pathogenic conditions associated with endosomal trafficking. Methods of treating or preventing an infection by a pathogen secreting an AB5 toxin is also contemplated.

Abstract: A thermal accelerant is delivered to a tissue site and localized to modulate the shape, extent or other characteristic of RF or microwave-induced hyperthermic tissue ablation. The accelerant may be provided via an image-guided hand piece or via a lumen added to a microwave antenna, and promotes faster heating, more complete ablation and/or a more extensive treatment region to reduce recurrence of treated cancers, overcoming natural limitations, variations in tissue response and drop-off or thermal loss away from the antenna. The accelerant is delivered as a low-viscosity but heat sensitive fluid, and is fixed in place to provide regions of preferential absorption or heating. Shorter exposure times to heat the far field may allow survival of vulnerable tissue such as vessels, and multiple antennae may be used for effective treatment of irregular or large tumors.

Abstract: The invention features methods for regulating vascular properties by controlling the membrane properties of endothelial cells using optogenetics and light. The invention features methods to transport therapeutics across the vascular barrier into tissues such as the brain and the lung, with high spatial and temporal precision, and for controlling vascular properties such as vascular tone, arterial diameter, and vascular growth.

Abstract: The present invention generally relates to devices and methods for containing molecules. In some embodiments, the device comprises a nanopore, a pore, and a cavity capable of entropically containing (e.g., trapping) a molecule (e.g., a biomolecule), e.g., for minutes, hours, or days. In certain embodiments, the method comprises urging a molecule into a cavity of a device by application of an electric field, and/or by deposition of fluids having different ionic strengths. The molecule may comprise, in some cases, nucleic acids (e.g., DNA). The molecule, when present in the cavity and/or the nanopore, may be capable of being analyzed, determined, or chemically modified. In some instances, a second molecule (e.g., a second molecule which interacts the first molecule) may also be urged into the cavity. In some embodiments, the interaction of the second molecule with the first molecule (e.g.

Abstract: Methods and systems for separating hydrocarbons using one or more dividing wall columns are provided. The method can include introducing a hydrocarbon fluid to a first dividing wall column. A first overhead comprising methane, ethane, or a combination thereof, a first intermediate comprising ethane, a second intermediate comprising ethane, and a first bottoms comprising one or more hydrocarbons having three or more carbon atoms per molecule can be recovered from the first dividing wall column. The first overhead can be introduced to a process for producing a liquefied natural gas. The first bottoms can be introduced to a second dividing wall column. A second overhead comprising propane, a third intermediate comprising butane, and a second bottoms comprising one or more hydrocarbons having five or more carbon atoms per molecule can be recovered from the second dividing wall column. The second overhead can be introduced to the process for producing a liquefied natural gas.

Abstract: Embodiments described generally relate to methods for assembling a modular floating production storage and offloading (FPSO) vessel. A cargo module section, a forward module, and a rear module can be positioned and aligned with each other such that the cargo module section can be disposed between the forward module and the rear module. A plurality of connectors can be coupled together to secure the forward module and the cargo module section together and another plurality of connectors can be coupled together to secure the rear module and the cargo module section together. A first topside module can be installed onto or over an upper surface of the forward module and can include a flare tower, a turret, hydrocarbon production equipment, or any combination thereof.

Abstract: This invention discloses a method of and composition for treating a PE-type disorder in a subject in need of such treatment comprising administering to the subject a pharmaceutical composition containing a therapeutically effective amount of a TTR polypeptide in admixture with a pharmaceutically acceptable vehicle.

Abstract: Systems, methods, and computer-readable storage media for simulating realistic clothing. The system generates a clothing deformation model for a clothing type, wherein the clothing deformation model factors a change of clothing shape due to rigid limb rotation, pose-independent body shape, and pose-dependent deformations. Next, the system generates a custom-shaped garment for a given body by mapping, via the clothing deformation model, body shape parameters to clothing shape parameters. The system then automatically dresses the given body with the custom-shaped garment.

Abstract: A fixation device including a base structure such as a faceplate having an inferior surface capable of contacting a surface of a skull of a patient, having a superior surface, and defining at least two securement features. Each securement feature can be engaged by a cranial fastener to attach the faceplate to the skull. The device further includes a fixation structure such as an alignment plate or a flexible fixation member carried by the base structure and positionable at least one of (i) over an opening in the skull and (ii) within an opening in the skull. At least one surface of the fixation structure defines at least one channel in which an intracranial device is capable of being placed, and further defines at least one fixation feature to enable the intracranial device to be secured to the fixation device.

Abstract: An arrow with self-aligning features allows a user to properly nock the arrow without resorting to manual alignment of the nock and fletchings. Engagement of a removable nock and shaft, each with a rounded polygonal cross-section, such as a reuleaux triangle, allow for a fixed relative angular position between the nock and the shaft without the use of an adhesive. This allows for proper position between the nock and index vane to ensure a more accurate path of the arrow during flight. Similarly, the reuleaux triangle cross-section of the shaft may engage an arrow head with a similar reuleaux triangle for accurate alignment between the shaft and the arrow head.

Abstract: A method and structure for a piezoelectric ink jet printhead. The method can include forming a piezoelectric composite from a liquid sol-gel solution. A first layer of the liquid sol-gel solution can be deposited onto a substrate using, for example, a spin coat process, wherein the substrate may be a printhead diaphragm. The first layer may be partially cured, then a second layer of the liquid sol-gel solution can be deposited onto the partially cured first layer, which is then partially cured. Any number of layers of liquid sol-gel solution can be deposited to result in a piezoelectric composite having a suitable thickness. Subsequently, all of the partially cured layers are fully cured. Printhead processing can continue to form a completed piezoelectric ink jet printhead.