Patents Assigned to Brown
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Patent number: 9193767Abstract: Provided herein are inventive enopeptin compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Further provided are methods of preparation, use, and treatment.Type: GrantFiled: March 30, 2012Date of Patent: November 24, 2015Assignee: Brown UniversityInventor: Jason K. Sello
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Patent number: 9193652Abstract: Methods and systems for purifying phenol. The method can include contacting a feed that includes phenol and an aldehyde containing compound with a first ion exchange material to produce a first treated product. The first treated product can have a pH that is less than a pH of the feed. The first treated product can contain less of the aldehyde containing compound than the feed. The first treated product can be contacted with a second ion exchange material to produce a second treated product. The second treated product can have a pH that is greater than the pH of the first treated product. Each of the first ion exchange material and the second ion exchange material can be a solid, a semi-solid, or a combination thereof.Type: GrantFiled: February 26, 2015Date of Patent: November 24, 2015Assignee: KELLOGG BROWN & ROOT LLCInventor: Theodor Wilks
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Patent number: 9189886Abstract: A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appear in minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping.Type: GrantFiled: August 14, 2009Date of Patent: November 17, 2015Assignee: Brown UniversityInventors: Michael J. Black, Alexandru O. Balan, Alexander W. Weiss, Leonid Sigal, Matthew M. Loper, Timothy S. St. Clair
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Publication number: 20150324646Abstract: According to some aspects, a wearable device for estimating a location of the device within a space is provided, the device comprising a plurality of cameras mounted to a structure, at least a portion of the structure being adapted to facilitate a user wearing the device, the plurality of cameras having substantially fixed positions and orientations on the structure relative to each other, and at least one processor configured to receive image data from the plurality of cameras, perform feature detection on the image data to obtain a first plurality of features from the image data, and determine an estimate of the location of the device in the space based, at least in part, on a location associated with a second plurality of features obtained from image data previously captured of the space that matches the first plurality of features.Type: ApplicationFiled: May 8, 2015Publication date: November 12, 2015Applicant: Brown UniversityInventor: Benjamin Kimia
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Publication number: 20150315763Abstract: A backfilling device for backfilling an open trench and padding a pipe within the trench has a lateral earth moving device and a sifting device. The backfilling device is attached to a tractor that moves the lateral earth moving device into a backfill spoil pile adjacent to the trench with the sifting device located above the trench. The lateral earth moving devices moves the backfill spoil material laterally into a rotating drum of the sifting device. Smaller particles of the backfill material fall through the rotating drum, which is also vibrating to backfill the trench and pad the pipe with backfill fines. The oversize debris in the backfill material continues to move laterally and falls out the end of the rotating drum to form a pile of large piece backfill material on the side of the trench opposite from the backfill spoil pile.Type: ApplicationFiled: May 1, 2014Publication date: November 5, 2015Applicant: Brown Bear CorporationInventor: Stanley L. Brown
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Patent number: 9169618Abstract: A backfilling device for backfilling an open trench and padding a pipe within the trench has a lateral earth moving device and a sifting device. The backfilling device is attached to a tractor that moves the lateral earth moving device into a backfill spoil pile adjacent to the trench with the sifting device located above the trench. The lateral earth moving devices moves the backfill spoil material laterally into a rotating drum of the sifting device. Smaller particles of the backfill material fall through the rotating drum, which is also vibrating to backfill the trench and pad the pipe with backfill fines. The oversize debris in the backfill material continues to move laterally and falls out the end of the rotating drum to form a pile of large piece backfill material on the side of the trench opposite from the backfill spoil pile.Type: GrantFiled: May 1, 2014Date of Patent: October 27, 2015Assignee: BROWN BEAR CORPORATIONInventor: Stanley L. Brown
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Patent number: 9169062Abstract: Methods, systems, and apparatus for mass flow are provided. The apparatus can include a housing, an inlet disposed at a first end of the housing, and an outlet disposed at a second end of the housing. The housing can include a first section and a second section. The second section can have at least one tapered sidewall that slopes away from an inner surface of the first section toward the outlet. The apparatus can also include a divider disposed at least partially within the first and second sections of the housing. The divider can have at least one tapered surface disposed proximate the at least one tapered sidewall of the second section. An edge of the divider can be located between the outlet and a point within the second section where the cross-sectional area of the second section is about three times or less a cross-sectional area of the outlet.Type: GrantFiled: June 30, 2011Date of Patent: October 27, 2015Assignee: KELLOGG BROWN & ROOT LLCInventors: Edwin V. Reece, John Abughazaleh, Michael J. Sandefur, David P. Mann
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Patent number: 9162830Abstract: Apparatus, systems, and methods for fluidizing particulates in a fluid/particulate mixture. A nozzle can include a gas entry segment, a gas exit segment, and an access segment. The gas exit segment can be coupled to the gas entry segment, and a longitudinal axis of the gas exit segment can be oriented at an angle of between about 70° and about 110° with respect to a longitudinal axis of the gas entry segment. The access segment can be coupled to the gas entry segment and the gas exit segment, and a longitudinal axis of the access segment can be substantially aligned with the longitudinal axis of the gas exit segment.Type: GrantFiled: December 22, 2010Date of Patent: October 20, 2015Assignee: KELLOGG BROWN & ROOT LLCInventor: William E. Phillips
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Patent number: 9165703Abstract: An effective method for prolonging localization of therapeutics within the rat gastrointestinal tract of at least about 12 hours is provided. The method includes localization of therapeutic agents that are nanoparticulated or nanoencapsulated. Attractive forces between an orally administered magnetic dose and an external magnet were monitored and internal dose motion in real time using biplanar videofluoroscopy was visualized. Tissue elasticity was quantified as a measure of tissue health by combining data streams. The methods address safety, efficacy, and monitoring capacity of magnetically localized doses and show a platform for testing the benefits of localized drug delivery.Type: GrantFiled: December 21, 2011Date of Patent: October 20, 2015Assignee: BROWN UNIVERSITYInventors: Bryan Laulicht, Edith Mathiowitz
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Patent number: 9162970Abstract: Methods and systems for purifying a crude aniline. The method can include contacting a crude aniline that can include aniline, water, and cyclohexanone with a cation exchange resin to produce a cyclohexanone-lean product that contains less cyclohexanone than the crude aniline. The cation exchange resin can be a solid, a semi-solid, or a combination thereof.Type: GrantFiled: February 26, 2015Date of Patent: October 20, 2015Assignee: KELLOGG BROWN & ROOT LLCInventors: Theodor Wilks, Eric Wing-Tak Wong, Matthew R. Ulrich
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Patent number: 9157043Abstract: Systems and methods for processing a hydrocarbon are provided. The method can include gasifying a feedstock within a gasifier to provide a raw syngas. The raw syngas can be processed within a purification system to provide a treated syngas. A first portion of the treated syngas can be converted into a first effluent in a first methanator. The first effluent can be mixed with a second portion of the treated syngas to provide a first mixed effluent. The first mixed effluent can be converted into a second effluent in a second methanator. The second effluent can be mixed with a third portion of the treated syngas to provide a second mixed effluent. The second mixed effluent can be converted into a third effluent in a third methanator.Type: GrantFiled: October 30, 2012Date of Patent: October 13, 2015Assignee: KELLOGG BROWN & ROOT LLCInventors: Siva Ariyapadi, Philip Shires
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Patent number: 9157042Abstract: Systems and methods for producing synthetic gas are provided. The method can include gasifying a feedstock within a gasifier to provide a raw syngas. The raw syngas can be processed within a purification system to provide a treated syngas, and the purification system can include a flash gas separator. The treated syngas and a first heat transfer medium can be converted into a synthetic gas, a second heat transfer medium, and a methanation condensate. The methanation condensate can be introduced to the flash gas separator.Type: GrantFiled: October 30, 2012Date of Patent: October 13, 2015Assignee: KELLOGG BROWN & ROOT LLCInventors: Siva Ariyapadi, Philip Shires
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Patent number: 9132401Abstract: Systems and methods for producing synthetic gas are provided. The method can include gasifying a carbonaceous feedstock in the presence of an oxidant within a gasifier to provide a raw syngas. The raw syngas can be cooled within a cooler to provide a cooled syngas. The cooled syngas can be processed within a purification system to provide a treated syngas. The purification system can include a saturator adapted to increase a moisture content of the cooled syngas. The treated syngas and a first heat transfer medium can be introduced to a methanator to provide a synthetic gas, a second heat transfer medium, and a methanation condensate. At least a portion of the methanation condensate can be recycled from the methanator to the saturator.Type: GrantFiled: October 30, 2012Date of Patent: September 15, 2015Assignee: KELLOG BROWN & ROOT LLCInventors: Siva Ariyapadi, Phillip Shires
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Patent number: 9132402Abstract: Apparatus, systems, and processes for reforming hydrocarbons are provided. The process can include reforming a first hydrocarbon in the presence of steam and one or more first catalysts in a first reformer to produce a first reformed hydrocarbon. The process can also include reforming the first reformed hydrocarbon in the presence of one or more second catalysts in a second reformer to produce a second reformed hydrocarbon. The process can also include reforming a second hydrocarbon in the presence of steam and one or more third catalysts in a third reformer to produce a third reformed hydrocarbon, where heat from the second reformed hydrocarbon is transferred to the second hydrocarbon to support reforming of the second hydrocarbon.Type: GrantFiled: April 1, 2010Date of Patent: September 15, 2015Assignee: KELLOGG BROWN & ROOT LLCInventors: Shashi Prakash Singh, Arthur Joseph Price
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Patent number: 9133405Abstract: Systems and methods for gasifying a feedstock are provided. The method can include combining one or more feedstocks and one or more solid components in a treatment zone to provide a treated feedstock. At least a portion of the treated feedstock can be introduced to a reaction zone of a gasifier. The one or more solid components can have an average density and an average cross-sectional size that adjusts at least one of an average density of solids within a solids bed of the gasifier and an average cross-sectional size of the solids within the solids bed of the gasifier.Type: GrantFiled: December 30, 2010Date of Patent: September 15, 2015Assignee: KELLOGG BROWN & ROOT LLCInventor: John Abughazaleh
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Publication number: 20150251988Abstract: Methods and systems for purifying a crude aniline. The method can include contacting a crude aniline that can include aniline, water, and cyclohexanone with a cation exchange resin to produce a cyclohexanone-lean product that contains less cyclohexanone than the crude aniline. The cation exchange resin can be a solid, a semi-solid, or a combination thereof.Type: ApplicationFiled: February 26, 2015Publication date: September 10, 2015Applicant: KELLOGG BROWN & ROOT LLCInventors: Theodor Wilks, Eric Wing-Tak Wong, Matthew R. Ulrich
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Publication number: 20150251984Abstract: Methods and systems for purifying phenol. The method can include contacting a feed that includes phenol and an aldehyde containing compound with a first ion exchange material to produce a first treated product. The first treated product can have a pH that is less than a pH of the feed. The first treated product can contain less of the aldehyde containing compound than the feed. The first treated product can be contacted with a second ion exchange material to produce a second treated product. The second treated product can have a pH that is greater than the pH of the first treated product. Each of the first ion exchange material and the second ion exchange material can be a solid, a semi-solid, or a combination thereof.Type: ApplicationFiled: February 26, 2015Publication date: September 10, 2015Applicant: KELLOGG BROWN & ROOT LLCInventor: THEODOR WILKS
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Publication number: 20150251918Abstract: Systems and methods for producing ammonia. The system can include a first ammonia converter, a second ammonia converter, a product separator, and an ammonia recovery unit. The first ammonia converter can be adapted to react a syngas to produce a first ammonia product and a first purge gas. The second ammonia converter can be in fluid communication with the first ammonia converter and can be adapted to react the first purge gas to produce an effluent. The product separator can be in fluid communication with the second ammonia converter and can be adapted to separate the effluent to produce a second ammonia product and a second purge gas. The ammonia recovery unit can be in fluid communication with the product separator and can be adapted to separate at least a portion of the second purge gas to produce a third ammonia product and a third purge gas.Type: ApplicationFiled: March 4, 2015Publication date: September 10, 2015Applicant: KELLOGG BROWN & ROOT LLCInventors: Trevor Williams Nurse, Girishkumar Natvarbhai Patel
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Patent number: 9126172Abstract: Reforming exchangers for syngas production are provided. The reforming exchangers can have a shell-and-tube configuration and include a shift catalyst on the shell side of the exchanger to reduce a carbon monoxide concentration in a shell side product gas mixture. Processes for forming syngas using the reforming exchangers are also provided.Type: GrantFiled: April 20, 2015Date of Patent: September 8, 2015Assignee: KELLOGG BROWN & ROOT LLCInventors: Shashi Singh, Kamal Gursahani, Robert Burlingame, Tim Weeks, Jim Gosnell, Avinash Malhotra
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Patent number: 9127897Abstract: Systems and methods for transporting a hydrocarbon are provided. The method can include introducing a fluid at a first pressure and a first temperature to an inlet of a pump and pressurizing the fluid within the pump to produce a pressurized fluid having a second pressure and a second temperature. The method can also include flowing at least a portion of the pressurized fluid through a first heat exchanger and back to the inlet of the pump. The heat exchanger can include a coil having an inlet and an outlet and a housing at least partially enclosing the coil and having a first opening and a second opening. A first end of the coil can be disposed proximate the first opening. The heat exchanger can also include a foundation for supporting the coil and the housing.Type: GrantFiled: December 30, 2010Date of Patent: September 8, 2015Assignee: KELLOGG BROWN & ROOT LLCInventor: Robert Hernandez