Patents Assigned to Brown
  • Cyclic peptidomimetic for the treatment of neurological disorders
    Patent number: 11879020
    Abstract: The present invention provides to compositions and methods useful in the treatment of neurological disorders including, but not limited to, Angelman syndrome, depression, traumatic brain injury, stroke, and Alzheimer's disease. CN2097, a rationally designed cyclic peptidomimetic drug that has been demonstrated to have effectiveness in preclinical models for the treatment of neurological disorders, is rapidly cleared and has a short half-life. The present invention provides a stable analog of CN2097.
    Type: Grant
    Filed: March 9, 2022
    Date of Patent: January 23, 2024
    Assignee: Brown University
    Inventor: John Marshall
  • SYSTEM AND METHOD USING MULTILAYER OPTICAL LATTICE QUBIT ARRAYS FOR QUANTUM COMPUTING
    Publication number: 20240020559
    Abstract: A quantum computing (QC) system includes a first plurality of logical qubits in a first substantially planar region and a second plurality of logical qubits in a second substantially planar region that is substantially parallel to the first substantially planar region. At least some of the first plurality of logical qubits are configured to interact with one another, and at least some of the second plurality of logical qubits are configured to interact with one another and to interact with the at least some of the first plurality of logical qubits. The QC system can include additional pluralities of logical qubits in additional substantially planar regions that are substantially parallel to the first and second substantially planar regions and at least some of the second plurality of logical qubits can be configured to interact with one or more of the additional pluralities of logical qubits.
    Type: Application
    Filed: May 6, 2022
    Publication date: January 18, 2024
    Applicant: Kellogg Brown & Root LLC
    Inventors: Peter Carl Hendrickson, Jadon Daniel Erwin
  • Bow sight adapted to connect to center line plane of riser
    Patent number: 11874088
    Abstract: An archery accessory, such as an archery sight, may attach to a riser of a bow along a centerline plane of the riser. This positioning may prevent or reduce any change in balance of the bow. The archery sight may include a sight element that may be adjusted in a horizontal direction by a horizontal adjustment system and in a vertical direction by one or more vertical adjustment systems.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: January 16, 2024
    Assignee: Brown Innovations, LLC
    Inventor: Kevin E. Brown
  • Integrated desolidification for solid-containing residues
    Patent number: 11859141
    Abstract: A desolidification process enables the isolation and extraction of solid additives from an unreacted petroleum residue stream. In a hydrocracking process that mixes a solid additive with a petroleum residue feedstock to convert the petroleum residue to higher-value distillates, the desolidification process enables the recovery of the unreacted petroleum residue for conversion to a saleable product. The desolidification process involves the mixture of one or more solvents with a slurry in which solids are integrated in the petroleum residue to generate a mixture having a decreased density and viscosity as compared to the slurry, which facilitates removal of the solids.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: January 2, 2024
    Assignee: KELLOGG BROWN & ROOT LLC
    Inventors: Cassandra Schoessow, Douglas Piotter, Anand Subramanian
  • Converting Motor Fuels Range Distillates to Light Olefins in a Multiple Riser Fluid Catalytic Cracking (FCC) Unit
    Publication number: 20230407187
    Abstract: Processes and systems for fluid catalytic cracking (FCC) of hydrocarbon feeds using a multiple riser FCC reactor are described. The conditions in each riser can be tailored for handling a different feed. For example, one riser may be configured to crack heavy hydrocarbons, such as vacuum gas oil (VGO) to yield medium and light products. Other risers may be configured to crack low and/or medium hydrocarbons to yield light olefins. Embodiments of the disclosed processes and systems may be used to provide a product spectrum that has greater amounts of light olefins.
    Type: Application
    Filed: June 17, 2022
    Publication date: December 21, 2023
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Rahul Pillai, Rajeev Ranjan
  • AMMONIA DISSOCIATION PROCESS
    Publication number: 20230406699
    Abstract: A process of dissociating ammonia into a dissociated hydrogen/nitrogen stream in catalyst tubes within a radiant tube furnace and an adiabatic or isothermal unit containing catalyst, along with downstream purification process units to purify the dissociated hydrogen/nitrogen stream into high purity hydrogen product.
    Type: Application
    Filed: June 16, 2023
    Publication date: December 21, 2023
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Khoa Dang Nguyen, Umesh Jain, Paolo Brunengo, Elena Stylianou, Rohit Khurana
  • Probabilistic object models for robust, repeatable pick-and-place
    Patent number: 11847841
    Abstract: A method includes, as a robot encounters an object, creating a probabilistic object model to identify, localize, and manipulate the object, the probabilistic object model using light fields to enable efficient inference for object detection and localization while incorporating information from every pixel observed from across multiple camera locations.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: December 19, 2023
    Assignee: Brown University
    Inventors: Stefanie Tellex, John Oberlin
  • REACTOR SYSTEM FOR SATURATED C3-C6 HYDROCARBON DEHYDROGENATION
    Publication number: 20230390722
    Abstract: A reactor system and method for catalytic dehydrogenation of saturated C3-C6 hydrocarbons within a reactor placed within a reactor disengager, where the reactor is open at the bottom thereof and open to the disengager, and the exit riser from the reactor is not hard coupled to at least one downstream cyclone. This configuration permits controlling the amount of catalyst within the reactor by varying the level of catalyst in the reactor disengager outside the reactor and permits controlling total catalyst hold-up and/or weight hourly space velocity (WHSV) independently from catalyst flow from the catalyst regenerator.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 7, 2023
    Applicant: Kellogg Brown & Root LLC
    Inventors: Rian Reyneke, Gautham Krishnaiah, Manoj Nagvekar, Mitchell Biondi, Steven Arthur Tragesser, Akhilesh Pratap, Froylan Guzman, Matthew James Griffiths, Christopher Brian Scharf
  • Recovery Of Light Olefins From Dry Hydrocarbon Gas From Refinery And Petrochemical Production Processes For Production Of Alkylate
    Publication number: 20230391691
    Abstract: Methods and systems for treating an olefin-containing stream are disclosed. The disclosed methods and systems are particularly suitable for treating an off-gas stream in a refining or petrochemical process, such as from a fluid catalytic cracker (FCC), coker, steam cracker, and the like. The stream is treated in an absorber column to reject lighter stream components and to absorb ethylene and/or propylene into a solvent. The solvent is typically isobutane. The enriched solvent stream from the absorber column is fed to an alkylation reactor, which reacts the dissolved olefin with the isobutane solvent to produce an alkylate product.
    Type: Application
    Filed: August 15, 2023
    Publication date: December 7, 2023
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Gautham Krishnaiah, Brian Heasley, John Lewis Webb, JR., Rahul Radhakrishna Pillai, Vijender K. Verma, Narinder Singh Duggal
  • INTEGRATED CARBON CAPTURE AND OLEFINS PRODUCTION PROCESS
    Publication number: 20230382728
    Abstract: Carbon capture of carbon dioxide (CO2) gives an extracted CO2 stream that is reacted with hydrogen to produce methanol (MeOH), which can in turn be fed to catalytic production of olefins such as ethylene and propylene to give an integrated process.
    Type: Application
    Filed: May 25, 2023
    Publication date: November 30, 2023
    Applicant: Kellogg Brown & Root LLC
    Inventor: Michael J. Tallman
  • Multi-parametric machine olfaction
    Patent number: 11828742
    Abstract: A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations.
    Type: Grant
    Filed: February 17, 2023
    Date of Patent: November 28, 2023
    Assignee: BROWN UNIVERSITY
    Inventors: Jacob K. Rosenstein, Christopher Rose
  • Compositions and methods for treating, preventing or reversing age associated inflammation and disorders
    Patent number: 11793814
    Abstract: Disclosed is a method for preventing, delaying or reversing age-associated inflammation, by administering to a patient in need thereof a therapeutically effective amount of at least one reverse transcriptase inhibitor (RTI).
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: October 24, 2023
    Assignee: Brown University
    Inventors: John M. Sedivy, Marco De Cecco
  • Methods of chemical computation
    Patent number: 11790280
    Abstract: The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: October 17, 2023
    Assignee: BROWN UNIVERSITY
    Inventors: Brenda Rubenstein, Jacob Karl Rosenstein, Christopher Arcadia, Shui Ling Chen, Amanda Doris Dombroski, Joseph D. Geiser, Eamonn Kennedy, Eunsuk Kim, Kady M. Oakley, Sherief Reda, Christopher Rose, Jason Kelby Sello, Hokchhay Tann, Peter Weber
  • Catalyst and process for ring opening polymerization
    Patent number: 11787821
    Abstract: The present invention discloses new catalyst systems based on trivalent metal complexes of Formula I, which can facilitate the stereospecific ring-opening polymerization of (rac)-?-Butyrolactone (rac-BBL). Also provided is a process for the stereospecific synthesis of aliphatic polyesters using the catalysts of Formula I, including alcohols and polyols as chain-transfer agents to facilitate immortal ring-opening polymerization.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: October 17, 2023
    Assignee: Brown University
    Inventors: Jerome R. Robinson, Xiang Dong
  • Methods and systems for producing pressware
    Patent number: 11780193
    Abstract: A system for forming a pressware product comprises rollers, a scoring tool, a scoring station actuator, a forming tool, and a forming station actuator. The rollers pull the web along a path having an angle. The scoring tool receives the material from the rollers and includes a vertically shiftable scoring punch with an edge that extends about an outline of the pressware product and a striker plate. The scoring station actuator shifts the scoring tool to form a slot in the web. The forming tool receives the scored web and includes a vertically shiftable positive mold assembly and negative mold assembly. The forming station actuator shifts the positive mold assembly to press against the web and form the pressware product.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: October 10, 2023
    Assignee: Brown LLC
    Inventors: Victor L. Chun, Steffen Brown, Russ Bliss, Philip Eichbauer, Brian Keeley, Robert Abel
  • Valve unit including a reinforcement mechanism with optional sensor assembly
    Patent number: 11781668
    Abstract: A valve unit may include a valve and a sensor assembly coupled to the valve. The valve may include a check disk configured to move along a pre-determined path to contact a valve seat in a closed state and configured to decouple from the valve seat in an open state. The valve may also include a mechanism to restrain lateral movement of the check disk to prevent the check disk from sticking. The sensor assembly may include a position sensor configured to generate a first electrical signal related to movement of the check disk and may include circuitry coupled to the position sensor. The position sensor assembly may generate a reference signal to eliminate noise within the first electrical signal. The circuitry may determine fluid flow parameters including flow volume of liquid components and of gas components of the fluid mixture based on frequency components within the first electrical signal.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: October 10, 2023
    Assignee: Brown Hawk Technologies LLC
    Inventors: Christopher Joseph Brown, Najmeh Brown
  • Methods of fabricating hyper compliant polymer particles and methods of use and compositions
    Patent number: 11772061
    Abstract: Compositions and methods are provided for making hyper compliant polymer particles by inverse emulsification and having a predetermined mechanical compliance and a predetermined size with a monodisperse diameter. Compositions and methods are provided for use of hyper compliant polymer particles in drug delivery, assay, particle image velocimetry, ceramics, cosmetics, deconvolution, electronic paper, insulation, personal care, standards, retroreflective paint and paint applications, thickening agents, regenerative medicine, device calibration, micro-carriers and force indicators.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: October 3, 2023
    Assignee: Brown University
    Inventors: Eric M. Darling, Nicholas R. Labriola, Edith Mathiowitz
  • Light fitting
    Patent number: D1002881
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: October 24, 2023
    Assignee: BROWN & WATSON INTERNATIONAL PTY LTD
    Inventor: Joshua Grabovic
  • Light bar
    Patent number: D1006273
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: November 28, 2023
    Assignee: BROWN & WATSON INTERNATIONAL PTY LTD
    Inventor: Mark Finocchiaro
  • Light bar
    Patent number: D1009323
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: December 26, 2023
    Assignee: BROWN & WATSON INTERNATIONAL PTY LTD
    Inventor: Mark Finocchiaro