Patents Assigned to Brown
  • Patent number: 12035996
    Abstract: An ultra high-resolution near infrared brain imager system includes a modular cap housing closely spaced multiple vertical-cavity surface-emitting laser-single-photon avalanche photodiode array (VCSEL-SPAD) modules, each one of the VCSEL-SPAD modules including a linear VCSEL array and a SPAD detector.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: July 16, 2024
    Assignee: BROWN UNIVERSITY
    Inventors: Arto Nurmikko, Ning Zhang
  • Publication number: 20240207801
    Abstract: A system for reactivating a catalyst having a predetermined heat content includes a reactor, a regenerator, and an electrically energized heater. The reactor is configured to generate a spent catalyst. The regenerator is configured to receive the spent catalyst from the reactor. The electrically energized heater has a plurality of energy emitting members at least partially immersed in the spent catalyst. The heater is configured to provide a supplemental heat content to obtain the predetermined heat content.
    Type: Application
    Filed: December 22, 2022
    Publication date: June 27, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Rian Reyneke, Matthew James Griffiths, Changwook Jeong, Manoj Nagvekar, Kyung Taek Han, Michael J. Tallman
  • Patent number: 12016624
    Abstract: A thermal accelerant is delivered to a tissue site and localized to modulate the shape, extent or other characteristic of RF or microwave-induced hyperthermic tissue ablation. The accelerant may be provided via an image-guided hand piece or via a lumen added to a microwave antenna, and promotes faster heating, more complete ablation and/or a more extensive treatment region to reduce recurrence of treated cancers, overcoming natural limitations, variations in tissue response and drop-off or thermal loss away from the antenna. The accelerant is delivered as a viscous but heat sensitive fluid, and is fixed in place to provide regions of preferential absorption or heating. Shorter exposure times to heat the far field may allow survival of vulnerable tissue such as vessels, and multiple antennae may be used for effective treatment of irregular or large tumors.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: June 25, 2024
    Assignees: Rhode Island Hospital, Brown University
    Inventors: William Keun Chan Park, Damian E. Dupuy
  • Publication number: 20240197745
    Abstract: Disclosed is a method for preventing, delaying or reversing age-associated inflammation, by administering to a patient in need thereof a therapeutically effective amount of at least one reverse transcriptase inhibitor (RTI).
    Type: Application
    Filed: September 19, 2023
    Publication date: June 20, 2024
    Applicant: BROWN UNIVERSITY
    Inventors: John M. SEDIVY, Marco DE CECCO
  • Publication number: 20240203724
    Abstract: The present disclosure generally relates to mass spectrometers, including but not limited to mass spectrometers able to emit ions at determinable times. In some aspects, the time between when ions leave an ion source and the time the ions reach a detector may be determined at a relatively high time resolutions, which may be useful for certain applications such as sequencing of biopolymers. In addition, in some cases, a relatively high number of ions leaving an ion source may be determined at a detector, e.g., at least 50% or more of the ions that are produced. Other aspects are generally directed to systems and methods for using such mass spectrometers, techniques involving such mass spectrometers, or the like.
    Type: Application
    Filed: April 22, 2022
    Publication date: June 20, 2024
    Applicant: Brown University
    Inventors: Derek M. Stein, Nicholas Drachman, Benjamin Wiener
  • Publication number: 20240177076
    Abstract: A method of evaluating one or more aspects of a low carbon ammonia production facility uses a digital twin implemented on a computer system. The digital twin includes a low carbon energy source component and one or more of: a hydrogen source component, a nitrogen source component, and an ammonia synthesis loop component.
    Type: Application
    Filed: November 17, 2023
    Publication date: May 30, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Zhentao Feng, Satish Bantwal Baliga, Ekaterini Yamalidou, Paolo Brunengo, Rafal Bernat
  • Publication number: 20240166484
    Abstract: There is disclosed an extractor (10) for extracting an elongate body (12) from the ground. The extractor (10) includes a holding assembly (14) operatively adapted to hold the elongate body (12) to be extracted from the ground and a guide assembly (24) operatively associated with the holding assembly (14). The guide assembly (24) includes (i) a guide follower (26) for operative attachment to the holding assembly (14), and (ii) a guide (28) along which the guide follower (26) is caused to move when the elongate body (12) is extracted from the ground. The extractor (10) further includes a drive assembly (30) operatively associated with the guide follower (26). The drive assembly (30) is adapted to be coupled with a hand tool for applying torque to the drive assembly (30). Applying torque to the drive assembly causes the guide follower (26) to move along the guide (28) thereby to extract the elongate body (12) from the ground.
    Type: Application
    Filed: November 20, 2023
    Publication date: May 23, 2024
    Applicant: Chester Brown Industries Pty Ltd
    Inventor: Peter Chester
  • Publication number: 20240166954
    Abstract: A system for processing a selected feedstock using a catalyst includes a reactor, a catalyst recovery system, and a conduit. The reactor receives the catalyst and the selected feedstock. A reaction between the selected feedstock and the catalyst generates a spent catalyst. The catalyst recovery system processes the spent catalyst. The conduit connects the reactor to the catalyst recovery system and has a lateral section. The spent catalyst flows from the reactor through a flow space defined by an inner wall of the lateral section to the catalyst recovery system. The system also includes a fluidizer positioned at the lateral section. The fluidizer includes at least one nozzle. The at least one nozzle is completely inside the flow space. The at least one nozzle forms and directs a jet of a fluidizing agent into the spent catalyst in the lateral section.
    Type: Application
    Filed: November 18, 2022
    Publication date: May 23, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Steve Arthur Tragesser, Matthew James Griffiths, Narinder Singh Duggal, Rahul Saxena, Akhilesh Pratap
  • Publication number: 20240165572
    Abstract: A system for processing a selected feedstock using a catalyst includes a reactor, a catalyst recovery system, and a conduit. The reactor receives the catalyst and the selected feedstock. A reaction between the selected feedstock and the catalyst generates a spent catalyst. The catalyst recovery system processes the spent catalyst. The conduit connects the reactor to the catalyst recovery system and has a lateral section. The spent catalyst flows from the reactor through a flow space defined by an inner wall of the lateral section to the catalyst recovery system. The system also includes a fluidizer positioned at the lateral section. The fluidizer includes at least one nozzle. The at least one nozzle is completely inside the flow space. The at least one nozzle forms and directs a jet of a fluidizing agent into the spent catalyst in the lateral section.
    Type: Application
    Filed: January 10, 2023
    Publication date: May 23, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Steve Arthur Tragesser, Matthew James Griffiths, Narinder Singh Duggal, Rahul Saxena, Akhilesh Pratap
  • Patent number: 11977317
    Abstract: A photon source for generating entangled photons includes a pump laser, and 4-N, N-dimethylamino-4?-N?-methyl-stilbazolium-tosylate (DAST) crystals, the pump laser pumping the DAST crystals with pump photons to generate a stream of pairs of entangled photons, each pair comprising a signal photon and an idler photon.
    Type: Grant
    Filed: February 16, 2023
    Date of Patent: May 7, 2024
    Assignee: Brown University
    Inventors: Jimmy Xu, Petr Moroshkin, Akshay Nagar
  • Publication number: 20240146058
    Abstract: Advanced control and related methods for a low carbon ammonia facility having an ammonia synthesis loop that includes systems to carry out the steps of supplying energy to the facility, wherein at least a portion of the supplied energy is from a low carbon energy source, receiving a forecasted energy profile for the low carbon energy source over a time period, predicting, using an advanced regulatory controller (ARC), the operating conditions of the facility based on the forecasted energy profile for the low carbon energy source, generating, by the ARC, one or more set points to control the facility; controlling the generating of the hydrogen feed using the ARC; and producing ammonia by feeding the generated hydrogen feed to the ammonia synthesis loop in accordance with one or more set points generated by the ARC.
    Type: Application
    Filed: October 20, 2023
    Publication date: May 2, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: Zhentao Feng, Satish Bantwal Baliga, Ekaterini Yamalidou, Paolo Brunengo, Rafal Bernat, Shoujun Bian
  • Publication number: 20240141240
    Abstract: A system and process for generating, on-site, a sustained C6+C7 aromatic rich solvent stream for tar solvation within the olefin plant employing a two-fuel oil tower system receiving a hydrocarbon feed from a quench water separator drum, where the two-fuel oil tower system is configured to make a sufficient solvent stream containing C6+C7 aromatic rich hydrocarbons that is recycled and mixed with quench water going to the quench water separator drum to assist in removing tar molecules out of the quench water.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 2, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: David Sellinger, Rian Reyneke, Quo-Chen Yeh, Alok Srivastava, Kristine E. Hamilton, Michael A. Radzicki, Larry J. Shulik, James R. Arnold
  • Patent number: 11970161
    Abstract: A motion planner of an autonomous vehicle's computer system uses reconfigurable collision detection architecture hardware to perform a collision assessment on a planning graph for the vehicle prior to execution of a motion plan. For edges on the planning graph, which represent transitions in states of the vehicle, the system sets a probability of collision with a dynamic object in the environment based at least in part on the collision assessment. Depending on whether the goal of the vehicle is to avoid or collide with a particular dynamic object in the environment, the system then performs an optimization to identify a path in the resulting planning graph with either a relatively high or relatively low potential of a collision with the particular dynamic object. The system then causes the actuator system of the vehicle to implement a motion plan with the applicable identified path based at least in part on the optimization.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: April 30, 2024
    Assignees: DUKE UNIVERSITY, BROWN UNIVERSITY
    Inventors: Daniel Sorin, William Floyd-Jones, Sean Murray, George Konidaris, William Walker
  • Patent number: 11972050
    Abstract: Instances of a single brain computer interface (BCI) system can be implemented on multiple devices. An active instance can control the associated device. The instances can each communicate with a neural decoding system that can receive neural signals from a user, process the neural signals, and output a command based on the processed neural signals. A device running the active instance of can be in communication with the neural decoding system to receive a command. The device can include a display, a non-transitory memory storing instructions, and a processor to execute the instructions to: run an instance of a control program; and execute the task based on the command.
    Type: Grant
    Filed: November 1, 2022
    Date of Patent: April 30, 2024
    Assignees: BROWN UNIVERSITY, THE GENERAL HOSPITAL CORPORATION, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Leigh Hochberg, John D. Simeral, Tyler Singer-Clark, Ronnie Gross, Thomas Hosman, Anastasia Kapitonava, Rekha Crawford
  • Patent number: 11964995
    Abstract: The present disclosure relates to a composition that includes a perovskite having a stoichiometry comprising A1-xFAxSn1-yBy(I1-zXz)3, where A is a first cation, B is a second cation, X is a halide, and 0.5?x?0.9, 0.5?y?0.9, and 0?z?1. In some embodiments of the present disclosure, A may include at least one of cesium, guanidinium, and/or methylammonium. In some embodiments of the present disclosure, X may include at least one of bromide and/or chloride. In some embodiments of the present disclosure, z may be equal to zero.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: April 23, 2024
    Assignees: Alliance for Sustainable Energy, LLC, Brown University
    Inventors: Kai Zhu, Jinhui Tong, Yuanyuan Zhou, Nitin P. Padture, Jue Gong
  • Patent number: 11957690
    Abstract: The invention provides a chromogenic ?-lactam molecule that retains its diagnostic color change response when modified for conjugation to another molecule.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: April 16, 2024
    Assignee: BROWN UNIVERSITY
    Inventors: Anita Shukla, Dahlia Alkekhia, Shashank Shukla, Hannah Safford
  • Patent number: 11957899
    Abstract: A system for placement of biocompatible electrodes in an opening formed in a patient's body part, such as DBS electrodes inserted into a patient's skull during surgical procedures in the brain. The system includes a coupled catheter and annulus. The catheter includes a guide tube having at least three cooperating guide elements configured to releasably fit together and collectively form a continuous lumen through the catheter that is dimensioned to receive an electrode therein. The annulus is configured to be placed in the opening formed in the patient's body part, and to receive the catheter therethrough. A track mechanism is used to operably couple the catheter to the annulus.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: April 16, 2024
    Assignee: Brown University
    Inventors: Wael Asaad, Shane Lee, Owen Leary, Noah Trac, Zakir Tahiry, Rohan Rastogi
  • Patent number: 11958046
    Abstract: Methods and systems for alkylate production involving a multi-zone alkylation reactor. The multi-zone alkylation reactor includes a plurality of alkylation zones spaced vertically in a series configuration and a partition splitting the plurality of alkylation zones into at least two mechanically separated catalytic volumes.
    Type: Grant
    Filed: June 16, 2023
    Date of Patent: April 16, 2024
    Assignee: KELLOGG BROWN & ROOT LLC
    Inventors: Rajeev Ranjan, Anubhav Kapil
  • Publication number: 20240116837
    Abstract: A system and a process for dimerizing cyclopentadiene (CPD) including producing a C6+C7 rich bottoms stream and a C5 rich side draw from a debutanizer, where the C5 rich side draw and at least a portion of the C6+C7 rich bottoms stream are directed to a dimerizer where the CPD is thermally dimerized to dicyclopentadiene (DCPD). DCPD is more stable than CPD and thus safer to handle.
    Type: Application
    Filed: December 19, 2023
    Publication date: April 11, 2024
    Applicant: KELLOGG BROWN & ROOT LLC
    Inventors: David Sellinger, Robert Choi, Quo-Chen Yeh, Alok Srivastava, Kristine E. Hamilton, Michael A. Radzicki
  • Patent number: D1035938
    Type: Grant
    Filed: June 2, 2022
    Date of Patent: July 16, 2024
    Assignee: BROWN & WATSON INTERNATIONAL PTY LTD
    Inventors: Michael Denham, Alex Morrison, Sergei Plishka, Alfred Blochlinger