Abstract: A spectacle lens with has permanent markings is mounted on a mounting, in particular a suction mounting. The apparent location of the permanent markings is detected on the spectacle lens with a detection device. Additionally, the spectacle lens is illuminated eccentrically with respect to an optical axis of the detection device using eccentric light sources. Reflections from the lights sources on the spectacle lens are likewise detected. On the basis of the detected reflections and the apparent location of the permanent markings, the position and/or orientation of the mounted spectacle lens are determined.

Abstract: A microscopy system for simultaneously observing fluorescent and non-fluorescent regions of an object, and a method for operating the microscopy system are provided. The microscopy system includes a microscopy optical unit configured to image an object plane through an observation beam path onto an image plane, an observation filter arrangeable in the observation beam path, two light sources, one being provided for exciting a fluorescent dye in the object and another being provided for visualizing non-fluorescent regions of the object, and a controller to control the light sources individually. With a suitable configuration of the observation filter, all light sources can be operated with a minimum operating current, which ensures the stability of the light. The color rendering of the non-fluorescent regions can be set by the individual settability of the light sources which can be set such that fluorescent and non-fluorescent regions appear to be approximately equally bright.

Abstract: The invention relates to an injector assembly having: a folding chamber which is designed to receive an intraocular lens which has an optical body and two haptic elements; a holder; a folding wedge which is attached to the holder and is designed to be introduced into the folding chamber via a folding chamber opening, thereby folding the intraocular lens; and a first slider and a second slider which are each designed to push one of the two haptic elements onto the optical body by means of a displacement of the respective slider from a starting position to an end position, the holder being designed to drive the first slider and/or the second slider from the starting position to the end position by means of a movement of the holder towards the folding chamber.

Abstract: An apparatus for classifying a brain tissue area as functional or non-functional by a stimulation of the brain includes a receiver unit for receiving information about a performed stimulation, a recording device for recording images that represent the brain tissue area, a detection unit for detecting a change in perfusion in the brain tissue area, and a classification unit configured to determine with the information whether there is a correlation between the performed stimulation and the detected change in perfusion, and to classify the brain tissue area as functional or as non-functional. The recording device is an endomicroscope for recording endomicroscopic images of the brain tissue area with a spatial resolution better than 20 ?m and a frame rate of at least 0.4 frames per second. The detection unit is configured to detect a change in perfusion based on the positions of certain tissue structures in the recorded images.

Abstract: A planning device that generates control data for an ophthalmological laser therapy appliance with a laser device and a control unit, includes a first interface for supplying various data and a second interface for transferring the control data to the control unit of the ophthalmological laser therapy appliance, which is embodied to generate control data for a scanning pattern for the ophthalmological laser therapy appliance from the supplied data, by application of which scanning pattern a structure can be produced in the cornea, the limbus, and/or the sclera of a patient's eye. The planning device is embodied to generate from the supplied data, control data for the scanning pattern of this structure and/or a structure for receiving the shunt implant.

Abstract: A spectacle lens design includes a first zone which has a focal power that provides a focused image on the fovea and a given a height and width. A second zone at least partly surrounds the first zone and contains at least one of the following: (i) focusing structures providing a focal power resulting in a myopic defocus or (ii) diffusing structures, such as scattering centers, leading to a diffusion of light passing the second zone. The first zone is curved to follow the converging line of sight of the wearer upon reading and contains a nasal segment, a temporal segment, and a central segment located between the nasal segment and the temporal segment The nasal segment and the temporal segment are shifted downwards with respect to the central segment.

Abstract: A family of spectacle lenses is provided in which each spectacle lens is configured to achieve a specified prescriptive spherical power from among a number of prescriptive spherical powers and a specified prescriptive astigmatic power from among a number of prescriptive astigmatic powers. Each spectacle lens has a specified rotationally symmetrical spectacle-lens front face, a specified atoric spectacle-lens rear face, and in at least one principal section, such a deviation in the curvature from the circular form that, for a value for the distance between the vertex of the spectacle lens rear face and the pivot point of the eye, which lies in a range between 15 and 40 mm, at any point in a spectacle lens region within a radius of 25 mm about the geometrical center of the spectacle lens, an upper limit of the total deviation of the power is not exceeded.

Abstract: A distance measuring device in microscopy contains a sample stage for arranging a sample carrier in a sample plane, and at least one, preferably at least two illumination sources for providing measurement radiation, which is reflected at least proportionally at a surface of the sample carrier. The device also contains a detection optical unit for capturing an overview image and occurring reflections at the sample carrier present in the sample plane; a detector disposed downstream of the detection optical unit and serving for the spatially resolved capture of image data of the sample carrier and of occurring reflections; and an evaluation device for ascertaining at least a distance of the surface at at least one location of the sample carrier. The illumination sources emit the measurement radiation in each case at a divergent emission angle. A corresponding method can be used for ascertaining a spatial orientation of a sample carrier.

Abstract: An apparatus for influencing an intraocular pressure (IOP) of an eye with a controllable discharge device which is configured to discharge a liquid from at least one area of the eye. The apparatus includes a first sensor device which captures at least one first value that is characteristic for the IOP of the eye, and a second sensor device, which captures at least one second value that is characteristic for a pressure acting on the eye, and a control device which controls the discharge device at least at times taking account of the first characteristic value and the second characteristic value, wherein the second characteristic value is characteristic for an intracranial pressure and/or cerebrospinal pressure.

Abstract: The disclosure relates to a method and a respective computer program with a program code to execute the method. In particular, disclosed is a method for training a preferred retinal locus of fixation (efficient PRL) for a person having an eye with a field of vision comprising an area of partially diminished or entirely degenerated visual acuity. The method includes: a) determining an inefficient retinal region outside the area in the field of vision of the eye of the person and a more efficient retinal region for the specific vision task outside the area in the field of vision of the eye of the person and b) inducing a preferred retinal locus of fixation (efficient PRL) for a vision task outside the inefficient retinal region but in the more efficient retinal region. In addition, the disclosure relates to a device for performing the method.

Abstract: A microscopy system comprises a microscope which can record at least one microscope image and a computing device which comprises a trained image processing model set up to calculate an image processing result based on the at least one microscope image. A method for verifying a trained image processing model, which can be performed by the computing device, can include receiving a validation image and an associated target image; entering the validation image into the trained image processing model, which calculates an output image therefrom; entering image data based on at least the output image and the associated target image into a trained verification model which is trained to calculate an evaluation that indicates a quality that depends on the image data for entered image data; and calculating an evaluation by the trained verification model based on the entered image data.

Abstract: Images are captured with a sample object in various arrangements relative to lighting and a detector. The images are then combined image point by image point on the basis of a comparison of image point values of image points of said images. This achieves a reduction in interference, i.e. reflections and/or shadows can be reduced.

Abstract: An overview image of a sample carrier is obtained in a method for ascertaining a measurement location of a microscope. A mapping or homography is determined, by means of which the overview image is perspectively convertible into a plan view image on the basis of a height of the sample carrier. The measurement location is identified, with the aid of the determined mapping/homography, in the overview image or in an output image derived therefrom.

Abstract: A method for training and using a machine learning system for a differentiation between healthy and diseased tissue during a microsurgical intervention is described. In this case, the method comprises: receiving training data and associated annotation data for training a machine learning system, training the machine learning system, which after training is configured for a prediction of a probability value and a prediction of a trustworthiness value, from which a control signal for a surgery assistance system is derivable, which is usable during a later application during a microsurgical operation, and storing parameter values of the trained machine learning model.

Abstract: A method evaluates a sample of measurement data from measuring multiple workpieces by at least one coordinate measuring machine. A system of statistical distributions describes a frequency of measurement data values. The distributions are distinguishable based on skewness and kurtosis. The method includes defining a set of statistical distributions that are able to describe a frequency of measurement data values in the entire value interval from the system of statistical distributions for a value interval of the measurement data, which is a specified value interval or a value interval of the measurement data actually arising in the sample. The method includes ascertaining the skewness and the kurtosis from the sample of measurement data corresponding to a first statistical distribution. The method includes checking, using the ascertained moment values, whether the defined set contains a statistical distribution that has the ascertained skewness and kurtosis, and producing a corresponding test result.

Abstract: A collision avoidance system and method for an x-ray CT microscope processes image data of an object at different angles and generates a model of the object. This model is then used to configure the microscope for operation and possibly avoid collisions between the microscope and the object.

Abstract: A field facet system for a lithography apparatus includes an optical element. The optical element includes a base section having an optically effective surface. The optical element also includes a plurality of lever sections provided at a rear side of the base section facing away from the optically effective surface. In addition, the field facet system includes two or more actuating elements configured, with the aid of the lever sections acting as levers, to apply in each case a bending moment to the base section to elastically deform the base section and thus to alter a radius of curvature of the optically effective surface. The actuating elements are arranged in series as viewed along a length direction of the optical element.

Abstract: A method of producing a workpiece includes obtaining CAD data representing the workpiece in multiple workpiece layers. The CAD data includes multiple workpiece layer definitions corresponding respectively to the workpiece layers. The method includes selecting a first workpiece layer definition, preparing a powder bed of powder material on a build platform, and producing, based on the selected workpiece layer definition, a workpiece layer on the build platform by controlling a layer tool to selectively melt or sinter the powder material on the build platform. The method includes assessing the produced workpiece layer, including measuring the produced workpiece layer using a measuring head, analyzing the measurements of the produced workpiece layer, and, in response to the analysis indicating that the produced workpiece layer is defective, reprocessing the produced workpiece layer by controlling the layer tool to selectively melt or sinter the powder material on the build platform.

Abstract: A x-ray micro tomography system provides the ability to proscriptively determine regularization parameters for iterative reconstruction of a sample, from projection data of the sample. This allows a less experienced operator to determine the regularization parameters with adequate precision.

Abstract: A brachytherapy apparatus and a brachytherapy method using the brachytherapy apparatus are provided. The brachytherapy apparatus includes a rod-shaped main element, a first holder, a second holder, side elements which extend between the first holder and the second holder and which are flexible and connected to the first holder and the second holder in such a way that a change in the relative position of the first holder in relation to the second holder brings about a change in the distance between the main element and the at least one side element, and a measuring apparatus configured to specify a measurement value based on at least one coordinate of the relative position of the first holder in relation to the second holder, said measurement value representing a quantity that depends on the distance.