Patents Assigned to CASCADE
  • DETECTING NUCLEIC ACID
    Publication number: 20140113292
    Abstract: This document provides methods and materials for detecting target nucleic acid. For example, methods and materials for detecting the presence or absence of target nucleic acid, methods and materials for detecting the amount of target nucleic acid present within a sample, kits for detecting the presence or absence of target nucleic acid, kits for detecting the amount of target nucleic acid present within a sample, and methods for making such kits are provided.
    Type: Application
    Filed: December 19, 2013
    Publication date: April 24, 2014
    Applicant: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, SR., Nina Yazvenko, Mariya Smit
  • METHODS AND MATERIALS FOR DETECTING CONTAMINATED FOOD PRODUCTS
    Publication number: 20140106339
    Abstract: This document provides methods and materials for detecting contaminated food products. For example, methods and materials for using an enzymatic amplification cascade of restriction endonucleases to detect nucleic acid of a microorganism or virus (e.g., a pathogen) within a sample (e.g., food product sample) being tested, thereby assessing a food product for possible contamination are provided.
    Type: Application
    Filed: November 26, 2013
    Publication date: April 17, 2014
    Applicant: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • Water treatment apparatus and process to reduce pipe scale and biomass using positive pressure ultraviolet oxygenation
    Patent number: 8696915
    Abstract: A method of treating water in order to minimize scaling and biomass buildup in water conduits or containers in which the treated water is used includes pressurizing and optionally filtering ambient air, processing the pressurized ambient air in a chamber including at least one ultraviolet light source operated to generate an output flow mixture of pressurized air and reactive oxygen species (ROS) gas, mixing the pressurized ROS/gas output mixture to realize a flow of water/pressurized ROS gas/air mixture and outputting the flow of water/pressurized ROS gas/air mixture as the treated water process product. The process includes generating reactive oxygen species (ROS) gas in the pressurized ROS/gas output mixture including at least one of Super Oxide (O2?), Peroxide (—O2—), Hydro peroxide (HO2?), Hydroxyl Radicals (OH.), Ozone (O3?) and Molecular Oxygen (O2).
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: April 15, 2014
    Assignee: Cascade Water Services
    Inventors: Eugene Klochkoff, Clive Ling, Steven Lerman
  • Chuck for supporting and retaining a test substrate and a calibration substrate
    Patent number: 8680879
    Abstract: A chuck for supporting and retaining a test substrate includes a device for supporting and retaining a calibration substrate. The chuck comprises a first support surface for supporting a test substrate and a second support surface, which is laterally offset to the first support surface, for supporting a calibration substrate. The calibration substrate has planar calibration standards for calibration of a measuring unit of a prober, and dielectric material or air situated below the calibration substrate at least in the area of the calibration standard. In order to be able to take the actual thermal conditions on the test substrate and in particular also on known and unknown calibration standards and thus the thermal influence on the electrical behavior of the calibration standard used into consideration, the second support surface is equipped for temperature control of the calibration substrate.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: March 25, 2014
    Assignee: Cascade Microtech, Inc.
    Inventors: Andrej Rumiantsev, Stojan Kanev, Steffen Schott, Karsten Stoll
  • METHODS AND MATERIALS FOR DETECTING GENETIC OR EPIGENETIC ELEMENTS
    Publication number: 20140057266
    Abstract: This document provides methods and materials for detecting genetic and/or epigenetic elements. For example, methods and materials for detecting the presence or absence of target nucleic acid containing a genetic or epigenetic element, methods and materials for detecting the amount of target nucleic acid containing a genetic or epigenetic element within a sample, kits for detecting the presence or absence of target nucleic acid containing a genetic or epigenetic element, kits for detecting the amount of target nucleic acid containing a genetic or epigenetic element present within a sample, and methods for making such kits are provided.
    Type: Application
    Filed: October 4, 2013
    Publication date: February 27, 2014
    Applicant: CASCADE BIOSYSTEMS, INC.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • RFID ASSEMBLY INCLUDING SPRING CLIP
    Publication number: 20140047681
    Abstract: An RFID assembly for securing an RFID device to a container. The assembly includes a clip having a first leg and a second leg connected by a resiliently flexible byte portion. The RFID device is attached to the clip. The assembly is inserted under and within an upper rim of a container, and the spring force provided by the byte portion secures the clip within the space, hidden from view. The first and/or second legs may include teeth to assist in securing the assembly in position.
    Type: Application
    Filed: August 14, 2012
    Publication date: February 20, 2014
    Applicant: CASCADE ENGINEERING, INC.
    Inventors: Jerry A. Walker, R. Michael Lewis, Bryan L. Schierbeek, John E. Misner, Kevin A. Bull
  • METHOD FOR TESTING A TEST SUBSTRATE UNDER DEFINED THERMAL CONDITIONS AND THERMALLY CONDITIONABLE PROBER
    Publication number: 20140028337
    Abstract: In a method and a device for testing a test substrate under defined thermal conditions, a substrate that is to be tested is held by a temperature-controllable chuck and is set to a defined temperature; the test substrate is positioned relative to test probes by at least one positioning device; and the test probes make contact with the test substrate for testing purposes. At least one component of the positioning device that is present in the vicinity of the temperature-controlled test substrate is set to a temperature that is independent of the temperature of the test substrate by a temperature-controlling device, and this temperature is held constant.
    Type: Application
    Filed: July 29, 2013
    Publication date: January 30, 2014
    Applicant: Cascade Microtech, Inc.
    Inventors: Joerg Kiesewetter, Stojan Kanev, Michael Teich, Karsten Stoll, Axel Schmidt
  • Detecting nucleic acid
    Patent number: 8632974
    Abstract: This document provides methods and materials for detecting target nucleic acid. For example, methods and materials for detecting the presence or absence of target nucleic acid, methods and materials for detecting the amount of target nucleic acid present within a sample, kits for detecting the presence or absence of target nucleic acid, kits for detecting the amount of target nucleic acid present within a sample, and methods for making such kits are provided.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: January 21, 2014
    Assignee: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • Water treatment apparatus and process to reduce pipe scale and biomass
    Patent number: 8628670
    Abstract: A method of treating water in order to minimize scaling and biomass buildup in water conduits or containers in which the treated water is used includes processing ambient air in a chamber including at least one ultraviolet light source to generate an output flow mixture of air and reactive oxygen species (ROS) gasses, controlling the at least one ultraviolet light source, a flow rate of the output flow mixture and an ROS gas ratio in the output flow mixture, mixing a water flow with the output flow mixture to realize a flow of water/ROS gas mixture and outputting the flow of water/ROS gas mixture as the treated water. Preferably, the processing includes generating reactive oxygen species (ROS) gasses in the output flow mixture including at least one of Super Oxide (O2?) Peroxide (—O2—), Hydroperoxide (HO2?), Hydroxyl Radicals (OH.), Ozone (O3?) and Molecular Oxygen (O2).
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: January 14, 2014
    Assignee: Cascade Water Services
    Inventors: Eugene Klochkoff, Clive Ling, Steven Lerman
  • Methods and materials for detecting contaminated food products
    Patent number: 8623616
    Abstract: This document provides methods and materials for detecting contaminated food products. For example, methods and materials for using an enzymatic amplification cascade of restriction endonucleases to detect nucleic acid of a microorganism or virus (e.g., a pathogen) within a sample (e.g., food product sample) being tested, thereby assessing a food product for possible contamination are provided.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: January 7, 2014
    Assignee: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • Carton Clamp Arm with Adjustable Pivot Block
    Publication number: 20130341943
    Abstract: A lift truck clamp arm assembly for engaging large cartons, which may contain large household appliances. Pivoting clamp pad support assemblies are adjustable to vary a radial spacing between a pivot pin and a clamp pad supported on the clamp arm assembly by attachment to the adjustable clamp pad support assembly, to provide desired pressure concentrations at selected parts of a carton to be gripped.
    Type: Application
    Filed: August 21, 2013
    Publication date: December 26, 2013
    Applicant: Cascade Corporation
    Inventors: Andrea Dal Dosso, Brian Sinclair White
  • METHODS AND MATERIALS FOR ASSESSING RNA EXPRESSION
    Publication number: 20130344578
    Abstract: This document provides methods and materials for assessing RNA expression. For example, methods and materials for detecting the presence, absence, or amount of target nucleic acid (e.g., target RNA or target cDNA produced from target RNA), kits for detecting the presence, absence, or amount of target nucleic acid (e.g., target RNA or target cDNA produced from target RNA), and methods for making such kits are provided.
    Type: Application
    Filed: June 19, 2013
    Publication date: December 26, 2013
    Applicant: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • MEMBRANE PROBING METHOD USING IMPROVED CONTACT
    Publication number: 20130321018
    Abstract: A substrate, preferably constructed of a ductile material and a tool having the desired shape of the resulting device for contacting contact pads on a test device is brought into contact with the substrate. The tool is preferably constructed of a material that is harder than the substrate so that a depression can be readily made therein. A dielectric (insulative) layer, that is preferably patterned, is supported by the substrate. A conductive material is located within the depressions and then preferably lapped to remove excess from the top surface of the dielectric layer and to provide a flat overall surface. A trace is patterned on the dielectric layer and the conductive material. A polyimide layer is then preferably patterned over the entire surface. The substrate is then removed by any suitable process.
    Type: Application
    Filed: May 23, 2013
    Publication date: December 5, 2013
    Applicant: CASCADE MICROTECH, INC.
    Inventors: Reed Gleason, Michael A. Bayne, Kenneth Smith, Timothy Lesher, Martin Koxxy
  • Methods and materials for detecting viral or microbial infections
    Patent number: 8597886
    Abstract: This document provides methods and materials for detecting target nucleic acid. For example, methods and materials for detecting the presence or absence of target nucleic acid, methods and materials for detecting the amount of target nucleic acid present within a sample, kits for detecting the presence or absence of target nucleic acid, kits for detecting the amount of target nucleic acid present within a sample, and methods for making such kits are provided.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: December 3, 2013
    Assignee: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • SYSTEMS AND METHODS FOR PREPARING AUTOLOGOUS FIBRIN GLUE
    Publication number: 20130299407
    Abstract: The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium is capable of separating red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also includes a transfer device having a cannula with a first end and a second end. The first and second ends are adapted to puncture the sealed primary and secondary containers in order to provide fluid communication between the first and second containers.
    Type: Application
    Filed: July 22, 2013
    Publication date: November 14, 2013
    Applicant: CASCADE MEDICAL ENTERPRISES, LLC
    Inventors: Roberto Beretta, Nicholas A. Grippi
  • Rotator braking system for a lift truck load handler
    Patent number: 8568079
    Abstract: A hydraulic rotating and braking system for a lift truck-mountable load handling assembly has a hydraulically-driven worm screw with a hydraulic motor located adjacent one end of the screw and a friction brake located adjacent the opposite end of the screw. The system includes a friction brake having a brake controller located at least partially within the worm screw. The friction brake is releasable by the exhaust of fluid without the need for a fluid exhaust line extending to the lift truck's reservoir tank.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: October 29, 2013
    Assignee: Cascade Corporation
    Inventors: Christopher M. Walthers, Robert J. Flak
  • Methods and materials for detecting genetic or epigenetic elements
    Patent number: 8551701
    Abstract: This document provides methods and materials for detecting genetic and/or epigenetic elements. For example, methods and materials for detecting the presence or absence of target nucleic acid containing a genetic or epigenetic element, methods and materials for detecting the amount of target nucleic acid containing a genetic or epigenetic element within a sample, kits for detecting the presence or absence of target nucleic acid containing a genetic or epigenetic element, kits for detecting the amount of target nucleic acid containing a genetic or epigenetic element present within a sample, and methods for making such kits are provided.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: October 8, 2013
    Assignee: Cascade Biosystems, Inc.
    Inventors: Kenneth D. Smith, Nina Yazvenko, Mariya Smit
  • Compositions and Methods for Preventing and Treating Mucositis and Weight Loss
    Publication number: 20130259930
    Abstract: Pharmaceutical compositions comprising 5-[2-pyrazinyl]-4-methyl-1,2-3-thione or an analogue, derivative, metabolite, prodrug, solvate or a pharmaceutically acceptable salt thereof; and a pharmaceutical carrier, which promotes association with the outer wall of a subject's digestive tract are described as well as their uses in treating and preventing mucositis and cachexia.
    Type: Application
    Filed: May 22, 2013
    Publication date: October 3, 2013
    Applicant: Cascade Estate Ltd.
    Inventor: Patrick T. Prendergast
  • Bicycle rack
    Patent number: D697837
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: January 21, 2014
    Assignee: Columbia Cascade Company
    Inventor: Steven K. Kirn
  • Carton clamp arm for a lift truck
    Patent number: D702412
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: April 8, 2014
    Assignee: Cascade Corporation
    Inventors: Andrea Dal Dosso, Brian Sinclair White