Patents Assigned to Cassella Aktiengesellschaft
  • Patent number: 5162555
    Abstract: The invention relates to a process for preparing a solution of a non-ferrous metal sulphonate by reacting a non-ferrous metal with a sulphonic acid, the non-ferrous metal being brought into contact with a sulphonic acid at a temperature of from 20.degree. to 120.degree. C. in the presence of oxygen or oxygen-containing gases.
    Type: Grant
    Filed: December 10, 1990
    Date of Patent: November 10, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Graalf Remmers, Horst Lieker
  • Patent number: 5160495
    Abstract: Monoazo dyestuffs useful for dyeing and printing hydrophobic fibers have the formula ##STR1## in which R.sup.1 denotes alkyl having 1 to 3 carbon atoms, R.sup.2 and R.sup.3 independently of one another denote alkyl having 2 to 5 carbon atoms and R.sup.4 denotes methyl or ethyl.
    Type: Grant
    Filed: October 29, 1990
    Date of Patent: November 3, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Reinhard Kuhn, Margareta Boos
  • Patent number: 5155109
    Abstract: The invention relates to pharmacologically active substituted 3-aminosydnone imines of the general formula I ##STR1## in which R.sup.1 denotes (C.sub.1 -C.sub.4)-alkyl, di-(C.sub.1 -C.sub.4)-alkylamino or (C.sub.6 -C.sub.12)-aryl, which can optionally be substituted by (C.sub.1 -C.sub.4)-alkyl;R.sup.2 denotes hydrogen or COR.sup.3 and R.sup.3 denotes (C.sub.1 -C.sub.4)-alkyl, (C.sub.1 -C.sub.4)-alkoxy, (C.sub.1 -C.sub.4)-alkoxy-(C.sub.1 -C.sub.4)-alkyl, acetoxy-(C.sub.1 -C.sub.4)-alkyl, (C.sub.6 -C.sub.12)-aryl, which can be substituted by (C.sub.1 -C.sub.4)-alkyl or (C.sub.1 -C.sub.4)-alkoxy, pyridyl, pyridyl(C.sub.1 -C.sub.4)alkyl or (C.sub.3 -C.sub.8)-cycloalkyland their pharmacologically acceptable acid addition salts.
    Type: Grant
    Filed: July 16, 1991
    Date of Patent: October 13, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Helmut Bohn, Melitta Just
  • Patent number: 5144040
    Abstract: In a process for preparing 2-substituted 1-(acylaminoalkyl)-2-imidazolines of the general formula I ##STR1## where R is an alkylene radical and R.sup.1 is a fatty acid radical, for example a fatty acid and a dialkylenetriamine are reacted with one another in a molar ratio of (1.8 to 2.0):1 by initially introducing one starting material at a temperature T.sub.1 and metering in the second starting material as a liquid, maintaining in the reaction mixture during the addition a temperature T.sub.1 and after the addition until the start of the cyclization a temperature T.sub.2 and distilling off the resulting water or alcohol via a rectification column and, after the acylation product has been formed, cyclizing in a conventional manner, T.sub.1 being a temperature of 170.degree. C. to the boiling point of the initially introduced starting material, but not higher than 250.degree. C., and T.sub.2 being a temperature of 170.degree. to 250.degree. C.
    Type: Grant
    Filed: September 4, 1990
    Date of Patent: September 1, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Georg-Wolfgang Eckhardt, Karl-Heinz Keil, Manfred Schrod
  • Patent number: 5120732
    Abstract: Substituted 3-aminosydnone imines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts, in which A denotes, for example, --CH.sub.2 --,R.sup.1 denotes hydrogen or the radical --COR.sup.5,R.sup.2, R.sup.3 denote alkyl having 1 to 4 C atoms,R.sup.5 denotes, for example, an aliphatic radical having 1 to 4 C atoms,and methods for preparing such compounds by cyclization of a compound of the formula II ##STR2## and if desired subsequent acylation. The invention also includes formulations containing effective amounts of such compounds, and methods for administering same to patients for the control and prophylaxis of cardiovascular disorders.
    Type: Grant
    Filed: August 29, 1990
    Date of Patent: June 9, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Helmut Bohn, Melitta Just
  • Patent number: 5110917
    Abstract: The present invention relates to water-soluble trisazo dyes of the formula T ##STR1## and process for the preparation thereof and to the use thereof.
    Type: Grant
    Filed: August 5, 1991
    Date of Patent: May 5, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Wolfgang Bauer, Willi Steckelberg, Josef Ritter
  • Patent number: 5102425
    Abstract: The present invention relates to a process for the dyeing and printing of blended fabrics made of polyester and natural fibre materials, characterized in that the polyester portion of the blended fabric is dyed and printed using one or more disperse dyes of the general formula I ##STR1## in which R is methyl, ethyl or alkyl having 2 or 3 C atoms, which is substituted by alkoxy having 1 to 3 C atoms, andR.sup.1 is alkyl having 1 to 3 atoms.
    Type: Grant
    Filed: January 22, 1991
    Date of Patent: April 7, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Klaus Hofmann, Margareta Boos, Reinhard Kuhn
  • Patent number: 5093307
    Abstract: Use of water-insoluble monoazo dyes of the formula I ##STR1## where X.sup.1 and X.sup.2 are each for example chlorine,X.sup.3 is for example hydrogen, methyl or alkoxy,Y is for example hydrogen, methyl, alkoxy or --NHCOR,R is hydrogen or alkyl,R.sup.1 is for example hydrogen, alkyl or alkenyl, andR.sup.2 is for example alkyl or alkenyl,in the sublimation transfer process.
    Type: Grant
    Filed: February 12, 1990
    Date of Patent: March 3, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Erika Kunz, Ulrich Buhler, Josef Ritter
  • Patent number: 5093529
    Abstract: In the process for the preparation of fluorinated benzoic acids of the formula I ##STR1## in which X and Y, for example, independently of one another denote chlorine or fluorine and X moreover denotes bromine, a fluorinated chloroacetophenone of the formula II ##STR2## in which Z denotes chlorine or hydrogen, is reacted with a hypohalite.
    Type: Grant
    Filed: July 16, 1990
    Date of Patent: March 3, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventor: Horst Schmand
  • Patent number: 5082059
    Abstract: The present invention relates to the use of hydrocarbon-rich gels as fracturing fluids and also to fracturing fluids which are composed of a hydrocarbon-rich gel and an auxiliary.
    Type: Grant
    Filed: October 22, 1990
    Date of Patent: January 21, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Gerlinde Ebert
  • Patent number: 5079244
    Abstract: Substituted 3-aminosydnone imines of the general formula I ##STR1## and their pharmacologically acceptable acid addition salts, in which A denotes an alkylene chain;X denotes one of the groups --O-- or --S--;R.sup.1 denotes e.g. hydrogen;R.sup.2 denotes e.g. an alkyl group,are prepared by cyclization of a compound of the formula II ##STR2## and, if appropriate, subsequent acylation, and have useful pharmacological properties.
    Type: Grant
    Filed: June 7, 1990
    Date of Patent: January 7, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Eckard Kujath, Christian Baumgartner, SchoKarl, Rudi Beyerle, Melitta Just, Helmut Bohn, Jorg Ostrowski
  • Patent number: 5071443
    Abstract: The dyestuff mixture contains at least one dyestuff of the formula I ##STR1## and at least one dyestuff of the formula II ##STR2## wherein X and Y denote chlorine or bromine,R.sup.1 and R.sup.5 denote methyl or ethyl,R.sup.2 and R.sup.6 denote methyl, ethyl, n-propyl or i-propyl andR.sup.3, R.sup.4, R.sup.7 and R.sup.8 denote, for example, C.sub.1 - to C.sub.11 -alkyl, in the weight ratio of I:II=(5 to 95):(95 to 5), and is, for example, outstandingly suitable for dyeing synthetic fibres.
    Type: Grant
    Filed: March 5, 1990
    Date of Patent: December 10, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Hubert Kruse, Manfred Hahnke, Margareta Boos, Reinhard Kuhn
  • Patent number: 5069682
    Abstract: The present invention relates to the .beta.-modification of the dye of the formula I ##STR1## to a process for its preparation, to its use, and to a dye preparation containing it.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: December 3, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Rudolf Binder, Friedrich Schophoff, Klaus Hofmann
  • Patent number: 5068298
    Abstract: The present invention relates to compounds of the general formula I ##STR1## in which R.sup.1, R.sup.1', R.sup.2, A and n are as defined in the description, a process for their preparation, their use and also hydrogels prepared using them.
    Type: Grant
    Filed: June 25, 1990
    Date of Patent: November 26, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Joachim Gersdorf, Hans-Jerg Kleiner
  • Patent number: 5066745
    Abstract: Alkenylphosphonic and -phosphinic acid esters of 1,1,1-tris(hydroxymethyl)alkanes and of 2,2-bis-hydroxymethyl-1,3-propanediol are useful as cross-linking agents in polymeric hydrogels.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: November 19, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Joachim Gersdorf, Hans-Jerg Kleiner
  • Patent number: 5043348
    Abstract: Pyrrolealdehydes of the formula I ##STR1## wherein R and R.sup.1 independently of one another denote hydrogen or alkyl with 1 to 4 C atoms, R.sup.2 denotes alkyl, which is substituted by acylamino of the formula II ##STR2## wherein X stands for an oxygen or sulphur atom and R.sup.3 denotes hydrogen, optionally substituted alkyl or alkylamino, cycloalkyl with 5 to 7 C atoms, optionally substituted phenyl, an amino group or an optionally substituted phenylamio group, and pharmaceutically acceptable acid addition salts thereof, and wherein R.sup.3 cannot represent hydrogen if R and R.sup.1 denote hydrogen and the pyrrole ring is formylated in the 3-position, their preparation and their use.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: August 27, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Gerhard Zoller, Rudi Beyerle, Ursula Schindler
  • Patent number: 5041553
    Abstract: In the process for the preparation of 2-substituted 1-(acylaminoalkyl)-2-imidazolines of the general formula I ##STR1## wherein R denotes an alkylene radical and R.sup.1 denotes a fatty acid radical, for example, a fatty acid and a dialkylenetriamine are reacted in a molar ratio of (1.9 to 2.0): 1 in such a way that the dialkylenetriamine is initially introduced hot under an inert gas atmosphere and the fatty acid is metered in hot and the amido amine formation is subsequently completed by heating to temperatures from 140.degree. to 190.degree. C. and the cyclization to the compound of the formula I is subsequently carried out at an under-pressure of at least 50 mbar.
    Type: Grant
    Filed: September 17, 1990
    Date of Patent: August 20, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl-Heinz Keil, Georg-Wolfgang Eckardt, Herbert Wirtz, Helmut Berenbold, Werner Wellbrock, Horst Frohlich
  • Patent number: 5015659
    Abstract: The present invention relates to thienylacetic acid derivatives of the general formula I ##STR1## in which X denotes --O-- or --NH--;R.sup.1 denotes hydrogen, the group --CH.sub.2 --CO--R.sup.3 or the group --CO--CH.sub.2 --NH.sub.2 ;R.sup.2 denotes hydrogen, (C.sub.1 -C.sub.4)-alkyl or the radical R.sup.1 andR.sup.3 denotes (C.sub.1 -C.sub.4)-alkoxy, hydroxyl or amino, it not being possible for both R.sup.1 and R.sup.2 to represent hydrogen when X denotes O,as well as the pharmaceutically tolerated salts thereof, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: May 14, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Ursula Schindler, Bernd Jablonka, Jeffery Troke
  • Patent number: 5006540
    Abstract: Substituted 3-aminosydnonimines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts, wherein R.sup.1 denotes, for example, alkyl having 1 to 8 C atoms, R.sup.2 denotes hydrogen or the radical --COR.sup.3 and R.sup.3 denotes, for example, an aliphatic radical having 1 to 4 C atoms, are prepared, for example, by cyclization of a compound of the formula II ##STR2## and if appropriate subsequent acylation and have useful pharmacological properties.
    Type: Grant
    Filed: October 17, 1989
    Date of Patent: April 9, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Melitta Just, Helmut Bohn, Jorg Ostrowski
  • Patent number: RE33908
    Abstract: Synthetic fiber materials are effectively colored by dyeing or printing with a dyestuff mixture containing at least two separate dyestuffs (I) and (II) in a weight ratio of (I):(II) of from (20 to 99):(80 to 1) wherein:(I) is at least one dyestuff of the formula ##STR1## and (II) is at least one dyestuff of the formula ##STR2## in which X and Y are the same or different and each is independently chloro and bromo:R.sup.1 and R.sup.
    Type: Grant
    Filed: February 19, 1991
    Date of Patent: May 5, 1992
    Assignee: Cassella Aktiengesellschaft
    Inventors: Horst Tappe, Hubert Kruse, Reinhard Kuhn, Albert Bode, Margareta Boos