Patents Assigned to Cassella Aktiengesellschaft
  • Thienylpiperazines, the use thereof and pharmaceuticals containing these
    Patent number: 4987134
    Abstract: The present invention relates to thienylpiperazines of the general formula I ##STR1## in which R.sup.1 denotes hydrogen or double-bonded oxygen and R.sup.2 denotes hydrogen or double-bonded oxygen, with R.sup.1 and R.sup.2 not both having the same meaning, as well as the pharmaceutically tolerated salts thereof, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof.
    Type: Grant
    Filed: March 16, 1990
    Date of Patent: January 22, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Ursula Schindler, Bernd Jablonka, Jeffery Troke
  • Mixtures of mon-azo dyestuffs for dyeing and printing hydrophobic synthetic fiber materials
    Patent number: 4985045
    Abstract: A monoazo dyestuff composition comprising at least two different individual compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are linear or branched alkyl having 1 to 4 carbon atoms and R is linear or branched alkyl having 1 to 5 carbon atoms, and where said individual compounds differ from each other in at least the R moiety, has improved dyeing properties compared with the individual dyestuffs when used to dye or print hydrophobic fiber materials.
    Type: Grant
    Filed: October 30, 1989
    Date of Patent: January 15, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Klaus Hofmann
  • Mixtures of monoazo dyes containing halogen and cyano substituents
    Patent number: 4985043
    Abstract: Mixtures of monoazo dyes suitable for dyeing and printing hydrophobic fiber materials and mixtures thereof with natural fibers contain one or more dyes of the formula I ##STR1## and one or more dyes of the formula II ##STR2## in which Hal denotes bromo or chloro; R.sup.1 and R.sup.2, independently of one another, denote methyl or ethyl; R.sup.3, R.sup.4, R.sup.5 and R.sup.6, independently of one another, denote linear alkyl having 1 to 4 carbon atoms or alkenyl having 3 or 4 carbon atoms; and R denotes methyl, acetylamino, propionylamino, i-butyrylamino, or n-butyrylamino.
    Type: Grant
    Filed: March 15, 1989
    Date of Patent: January 15, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Manfred Hahnke, Reinhard Kuhn, Margarete Boos
  • Polybase from amino amido carboxylic acid, polyamine and difunctional alkylating agent
    Patent number: 4977239
    Abstract: A water-soluble organic polybase which is useful for the cationization of asbestos-free, cellulose fiber filter media is prepared by reacting a mixture of a compound of the formulaR.sup.2 --CO--R.sup.1 --COOHand a polyalkyleneimine with a difunctional alkylating agent, wherein R.sup.1 is a single bond or alkylene having 1 to 10 carbon atoms and R.sup.2 is inter alia a moiety of the formulaH.sub.2 N--(CH.sub.2).sub.u --NH--(CH.sub.2).sub.u --NH).sub.wwherein u is the number 2, 3, 4 or 5 and w is the number 0, 1, 2 or 3.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: December 11, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Walter Kamutzki, Karl-Heinz Keil
  • Water-soluble aminonaphthol disazo dyestuffs, their preparation and their use
    Patent number: 4973672
    Abstract: Coloring natural or synthetic fiber material containing hydroxyls or nitrogen is achieved by printing or dyeing the fiber material with a water-soluble disazo dyestuff of the formula ##STR1## wherein R.sup.1 is alkyl, alkoxy or alkoxyethoxy, each having 3-6 carbon atoms, B.sup.1 is the radical of a 1-amino-8-hydroxynaphthalene monosulphonic or disulphonic acid and B.sup.2 is the same as B.sup.1 or another napthyl moiety.
    Type: Grant
    Filed: March 27, 1989
    Date of Patent: November 27, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Wolfgang Bauer, Klaus Hunger
  • Pyrrole derivatives, their preparation and their use as pharmaceutical active compounds
    Patent number: 4966901
    Abstract: Pyrrole derivatives of the general formula I ##STR1## wherein R denotes alkyl which is substituted by --NH.sub.2 or acylamino, R.sup.1 and R.sup.2 independently of one another denote hydrogen or alkyl having 1 to 4 carbon atoms, R.sup.3 denotes hydrogen, alkyl having 1 to 4 carbon atoms or a carboxylic acid grouping, R.sup.
    Type: Grant
    Filed: May 23, 1989
    Date of Patent: October 30, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Gerhard Zoller, Rudi Beyerle, Ursula Schindler
  • Alkenylphosphonic and -phosphinic acid esters, process for their preparation, hydrogels produced using them, and their use
    Patent number: 4959441
    Abstract: Alkenylphosphonic and -phosphinic acid esters of 1,1,1-tris(hydroxymethyl)alkanes and of 2,2-bis-hydroxymethyl-1,3-propanediol are useful as cross-linking agents in polymeric hydrogels.
    Type: Grant
    Filed: May 8, 1989
    Date of Patent: September 25, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Joachim Gersdorf, Hans-Jerg Kleiner
  • Water-insoluble monoazo dyes, their preparation and use, and mixtures of these monoazo dyes
    Patent number: 4950305
    Abstract: Hydrophobic textile materials can be dyed or printed with one or more monoazo dyes of the formula ##STR1## in which R.sup.1 is fluoro, chloro or bromo;R.sup.2 is hydrogen or chloro; andR.sup.3 is allyl, alkyl having 1 to 4 carbon atoms, alkoxyalkyl having 2 to 4 carbon atoms in the alkyl portion and 1 to 4 carbon atoms in the alkoxy portion or cyanoalkyl having 2 to 4 carbon atoms.
    Type: Grant
    Filed: August 7, 1989
    Date of Patent: August 21, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Margareta Boos, Reinhard Kuhn
  • Substituted 3-aminosydnonimines, processes for their preparation and their use
    Patent number: 4937244
    Abstract: Substituted 3-aminosydnonimines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts wherein A denotes, for example, --CH.sub.2 --,R.sup.1 denotes hydrogen or the radical --COR.sup.7,R.sup.2, R.sup.3, R.sup.4 and R.sup.5 denote alkyl with 1 to 4 C atoms andR.sup.7 denotes, for example, an aliphatic radical and 1 to 4 C atoms, are prepared by cyclization of a compound of the formula II ##STR2## and if appropriate subsequent acylation and have useful pharmacological properties. The invention includes pharmaceutical preparations containing the present compounds, and the use thereof for treating patients having cardiovascular ailments.
    Type: Grant
    Filed: August 3, 1988
    Date of Patent: June 26, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle
  • N-substituted N-nitrosoaminoacetonitriles, process for their preparation and their use
    Patent number: 4937241
    Abstract: Pharmacologically useful N-substituted-N-nitrosoaminoacetonitriles of the general formula I ##STR1## wherein A denotes the radical --CH.sub.2 --, --O--, --S(O.sub.n)--, --N(R.sup.2)-- or a direct bond,R.sup.1 and R.sup.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: June 26, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Helmut Bohn
  • Process for dyeing and printing synthetic fibers with mixtures of monoazo dyestuffs
    Patent number: 4937325
    Abstract: A monoazo dyestuff composition comprising at least two different individual compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are linear or branched alkyl having 1 to 4 carbon atoms and R is linear or branched alkyl having 1 to 5 carbon atoms, and where said individual compounds differ from each other in at least the R moiety. The monoazo dyestuff mixtures are used for the dyeing and printing of hydrophobic fibers such as high molecular weight polyesters of their mixtures with natural fiber material.
    Type: Grant
    Filed: December 12, 1988
    Date of Patent: June 26, 1990
    Assignees: Cassella Aktiengesellschaft, Tokico Ltd.
    Inventors: Ulrich Buhler, Klaus Hofmann, Hiroshi Mitsuhashi, Harutsugu Ushiota, Akiharu Odagiri, Gen Kano, Susumu Sakamoto
  • Hydrophilic swellable graft polymers from maleic anhydride-alkylene substrate
    Patent number: 4931497
    Abstract: The present invention relates to hydrophilic swellable graft polymers which consist, in random distribution, to the extent of 0.5 to 20% by weight of radicals of the general formula I ##STR1## 79 to 99% by weight of radicals containing an acid group, of the general formula II ##STR2## and 0.1 to 2% by weight of crosslinking structures originating from monomers with at least two olefinically unsaturated double bonds, wherein the radicals R.sup.1 to R.sup.4 and n have the meanings given in claim 1, these graft polymers being used as absorbants for water and aqueous solutions.
    Type: Grant
    Filed: October 28, 1988
    Date of Patent: June 5, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ullrich Riegel
  • Liquid formulations of 1,2-benzisothiazolin-3-one, their preparation and their use
    Patent number: 4923887
    Abstract: Antimicrobially active liquid composition formulation which comprises 1,2-benzisothiazolin-3-one and at least one amine-oxyethylate of the formula ##STR1## wherein R is alkyl or alkenyl each having 2 to 22 carbon atoms and the sum of m and n is a number from 2 to 30 is used as an improved biocide to preserve and protect aqueous solutions from infestation with micro-organisms.
    Type: Grant
    Filed: August 25, 1988
    Date of Patent: May 8, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Wolfgang Bauer, Hans-Walter Bucking, Karl-Heinz Wallhausser
  • Process for the preparation of new crystal modification of an azo dyestuff
    Patent number: 4921505
    Abstract: In the process for the preparation of the dyestuff of the formula I ##STR1## by diazotization and coupling, the aqueous suspension present when the coupling has ended is heated to temperatures of 50.degree. C. up to the boiling point of the aqueous phase in the presence of a dispersing agent.
    Type: Grant
    Filed: December 12, 1988
    Date of Patent: May 1, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Gunther Effenberger, Hubert Kruse
  • Use of 2-oxo-1-pyrrolidineacetamide for the determination of the glomerular filtration rate in humans
    Patent number: 4908202
    Abstract: The use of 2-oxo-1-pyrrolidineacetamide for the determination of the glomerular filtration rate in humans.
    Type: Grant
    Filed: January 23, 1989
    Date of Patent: March 13, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventor: Hans-Ulrich Schulz
  • Thienylpiperazinones, their preparation and their use
    Patent number: 4898866
    Abstract: 3-(Thien-2-yl)-piperazin-2-ones, substituted in the 3-position, of the general formula ##STR1## wherein R dentoes, for example, phenyl or (C.sub.1 -C.sub.6)-alkyl and R.sup.1 denotes 2-thienyl and pharmacologically tolerable acid addition salts thereof, which possess valuable nootropic properties. The invention also includes methods for making such compounds, formulations containing such compounds and methods for treating a host in need thereof.
    Type: Grant
    Filed: May 9, 1989
    Date of Patent: February 6, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Ursula Schindler
  • Water-soluble yellow monoazo dyestuffs
    Patent number: 4881977
    Abstract: Water-soluble, yellow monoazo dyestuffs of the formula ##STR1## wherein R.sup.1 is a moiety of the formula ##STR2## R.sup.2 is methyl, ethyl, methoxy or ethoxy, R.sup.3 is methyl or ethyl, andn is a number from 0.3 to 1.7,are useful for the preparation of recording fluids.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: November 21, 1989
    Assignee: Cassella Aktiengesellschaft
    Inventors: Wolfgang Bauer, Willi Steckelberg, Josef Ritter
  • Methylolated and optionally etherified urethanes containing fluoroalkyl ligands
    Patent number: 4877540
    Abstract: Methylolated and optionally etherified urethanes containing fluoroalkyl ligans with formaldehyde, with or witout subsequent etherification, and are in the form of their solutions or aqueous dispersions suitable for the treatment of textiles and leather.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: October 31, 1989
    Assignee: Cassella Aktiengesellschaft
    Inventors: Fritz Engelhardt, Karl Hintermeier, Manfred Muller, Norbert Munch, Hans Wagener
  • Aqueous formulation of 1,2-benzisothiazolin-3-one
    Patent number: 4871754
    Abstract: Aqueous solutions are protected from infestation by micro-organisms by use of a biocide which is an aqueous formulation of the lithium salt of 1,2-benzisothiazolin-3-one.
    Type: Grant
    Filed: December 18, 1986
    Date of Patent: October 3, 1989
    Assignee: Cassella Aktiengesellschaft
    Inventors: Wolfgang Bauer, Willi Steckelberg
  • Mixtures of blue disperse monoazo dyestuffs
    Patent number: 4851012
    Abstract: A mixture of monoazo dyestuffs which contains one or more dyestuffs of the formula I ##STR1## and one or more dyestuffs of the formula II ##STR2## wherein R.sup.1 and R.sup.2 independently of one another each denote linear or branched alkyl with 1 to 6 carbon atoms, R denotes linear or branched alkyl with 1 to 5 carbon atoms and Hal denotes chloro or bromo, are outstandingly suitable for dyeing and printing hydrophobic materials.
    Type: Grant
    Filed: February 1, 1988
    Date of Patent: July 25, 1989
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Hubert Kruse, Reinhard Kuhn, Margareta Boos