Abstract: The invention relates to substituted 3-amino-1-arylalkyl-benzazepin-2-ones of the general formula ##STR1## wherein Ar is aryl;X is --O-- or --S(O).sub.n -- and n is 0, 1 or 2;X.sub.1 is C.sub.1 -C.sub.2 alkylene or a direct bond;R.sub.1 is hydrogen, lower alkyl, aryl-lower alkyl or acyl;R.sub.2 is lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, aryl-lower alkoxy-lower alkyl, aryl-lower alkyl or C.sub.3 -C.sub.7 cycloalkyl-lower alkyl;R.sub.3 is carboxy; lower alkoxycarbonyl; lower alkoxy-lower alkoxycarbonyl; aryl-lower alkoxycarbonyl; aryloxycarbonyl; carbamoyl; carbamoyl that (i) is monosubstituted by hydroxy, lower alkanesulfonyl, halo-lower alkanesulfonyl or by arylsulfonyl, (ii) is monosubstituted or disubstituted, the substituents being independent of one another, by lower alkyl, lower alkenyl, lower alkynyl or by phenyl-lower alkyl or (iii) is disubstituted by lower alkylene or by lower alkylene-Z.sub.1 -lower alkylene, Z.sub.1 being O, S or NH; 5-tetrazolyl; PO.sub.2 H.sub.2 ; PO.sub.3 H.

Abstract: The present invention provides a stable aqueous solution of hybrid .alpha.-Interferon which contains as the stabilizer a buffer at a pH of from 3.0 to 5.0.

Abstract: Compounds of the formula (I) ##STR1## in which n is zero or 1, X denotes a group of formula (II), ##STR2## R.sub.1 and R.sub.5 are e.g. hydrogen, R.sub.2, R.sub.3 and R.sub.4, which may be identical or different, are C.sub.2 -C.sub.12 alkylene, R.sub.6 is e.g. hydrogen or C.sub.1 -C.sub.18 alkyl and R.sub.7 is e.g. hydrogen or C.sub.1 -C.sub.8 alkyl, are useful as stabilizers for organic materials against degradation induced by light, heat or oxidation.

Abstract: The present invention is drawn to the production of fertile transformed wheat plants. The method involved subjecting wheat tissues to high velocity microprojectile bombardment, selecting for transformed cells, and regenerating stably transformed fertile plants from the transformed cells.

Abstract: The invention relates to compounds of the following general formula I ##STR1## especially the compound of formula Ia referred to as thiangazole ##STR2## their pharmaceutically acceptable acid addition salts, processes for their preparation and therapeutic compositions and compositions that can be used in crop-protection.

Abstract: Compounds of formula (I) in which (a) four of the radicals R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are hydrogen and the others independently of one another are in each case C.sub.1 -C.sub.2 alkyl, these groups being bonded to the same carbon atom or to two different carbon atoms, or (b) five of the radicals R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are hydrogen and the other radical is C.sub.1 -C.sub.2 alkyl or hydroxymethyl, or salts thereof, are described. The compounds of formula (I) and their salts are ornithine decarboxylase inhibitors.

Abstract: A preservative for ophthalmic solutions having an active ingredient is provided, having a hydrogen peroxide content of about 0.001% to about 0.10% by weight; and diethylene triamine penta(methylene phosphonic acid) or a physiologically compatible salt thereof, present at about 0.002% to 0.03% by weight and/or 0.005% to about 0.20% by weight of 1-hydroxyethylidene-1,1-diphosphonic acid, or physiologically acceptable salt thereof.

Abstract: A process for the preparation of compounds of formula I ##STR1## wherein the general symbols are as defined in claim 1, which comprises reacting a compound of formula III ##STR2## wherein the general symbols are as defined in claim 1, with a compound of formula IV[H].sub.n --R.sub.1 (IV).

Abstract: Methods of deblocking a polymeric article from a mold and/or removing undesirable materials from a polymeric article by applying supercritical fluids to the polymeric article. A preferred process is the treatment of ophthalmic lenses, such as contact lenses. Supercritical fluid, composed primarily of carbon dioxide, is applied to a contact lens affixed to a mold subsequent to the polymerization step. The application of supercritical fluid (SCF) causes the lens to efficiently and consistently separate from the mold, removes undesirable materials such as unreacted monomer, oligomers, or residual solvents from the lens core, and/or cleans the lens surface of adhered debris.

Abstract: Soluble and thermally stable benzotriazole UV absorbers typified by those of formula I ##STR1## where R.sub.1 is hydrogen or chloro, R.sub.2 is alkyl or --CH.sub.2 CH.sub.2 COOR.sub.4 where R.sub.4 is hydrogen, alkyl or alkyl substituted with hydroxyl, and R.sub.3 is .alpha.-cumyl, provide excellent light stability protection to electro coat, base coat or clear coat finishes. The new soluble, crystalline form of 2-(2-hydroxy-3-.alpha.-cumyl-5-tert-octylphenyl)-2H-benzotriazole is particularly effective.

Abstract: A process for the preparation of 6-alkyl-4-(pyridin-3-yl-methyleneamino)-4,5-dihydro-1,2,4-triazin-3(2H)-on e by the reaction of 4-amino-6-alkyl-3-oxo-2,3,4,5-tetrahydro-1,2,4-triazine with 3-cyanopyridine wherein the reaction is carried out under catalytic hydrogenation conditions in the presence of a Raney-nickel catalyst in an aqueous alcoholic medium, at a temperature between 0.degree. and 70.degree. C., at a pH of between 2 and 7, and in the presence of and a C.sub.1 -C.sub.6 -carboxylic acid or a C.sub.1 -C.sub.6 -carboxylic acid alkali metal salt or both, whereby the hydrogen pressure is between 0.1 and 10 bar.

Abstract: Polyamic acids and corresponding polyimides are prepared by reacting phenylindane diamines, aromatic polyfunctional anhydrides or esters thereof, and nadic anhydride or allylnadic anhydride end capping agents, the resulting products exhibiting excellent properties and being suitable for the preparation of prepregs, composites, adhesives, coatings, and the like.

Abstract: The invention relates to novel aromatic acids, especially to compounds of formula ##STR1## wherein R.sub.1 is lower alkyl, R.sub.2 is lower alkyl, R.sub.3 is hydrogen, carboxy or sulfo, R.sub.4 is carboxy or sulfo, G is an unsubstituted or substituted 1,4-phenylene group or an unsubstituted or substituted 1,4-naphthylene group, and wherein either R.sub.5 and R.sub.6 together are an additional bond and L is an oxygen or sulfur atom or wherein R.sub.5 is hydrogen, R.sub.6 is halomethyl and L is an oxygen atom, and salts thereof, to the use of compounds I and their salts, to a process for the preparation of compounds I and their salts, to starting materials used in that preparation process, and salts thereof, to a process for the preparation of those starting materials and their salts, to a device in which the compounds I and their salts are used, and to a process in which that device is used.

Abstract: The invention discloses a process for the preparation of azo dyes using an aminodiphenylamine as diazo component. The process comprises reacting the amine, an alkali metal nitrite and a mineral acid continuously in the temperature range from 35.degree. to 65.degree. C. to give the diazo compound, using a 3 to 15% excess of alkali metal nitrite, and thereafter coupling the diazo compound to a coupling component. Azo dyes of superior quality constancy and in high yield are obtained by the novel process.

Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is free or esterified carboxy, hydroxymethyl or formyl,R.sub.2 and R.sub.4 are each independently of the other aliphatic, cycloaliphatic-aliphatic, araliphatic or heteroarylaliphatic radicals andR.sub.3 is azido, or amino that is aliphatically or araliphatically substituted and/or protected by an amino-protecting group,and the salts thereof, are valuable intermediates in the preparation of medicinal active ingredients, for example of compounds of formula II ##STR2## wherein R.sub.A is an aromatic or heteroaromatic radical,R.sub.2 and R.sub.4 are each independently of the other aliphatic, cycloaliphatic, cycloaliphaticaliphatic or araliphatic radicals,R.sub.3 is unsubstituted or N-mono- or N,N-di-lower alkylated or N-lower alkanoylated amino, andR.sub.B is an aliphatically, cycloaliphatically or heteroaromatically-aliphatically substituted amino group,and the salts thereof, which can be used, for example, as antihypertensives.

Abstract: 2-Aminooxymethylenephenylacetic acid ester derivatives of the formula ##STR1## wherein Z.sub.1 and Z.sub.2 are hydrogen, halogen, hydroxy, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkylcarbonyl, phenoxy, nitro or cyano, or Z.sub.1 and Z.sub.2, together with the linking phenyl radical, are naphthalene or hydrogenated naphthalene, and R.sub.3 is hydrogen or C.sub.1 -C.sub.12 alkyl. The compounds of this invention may be used as the free base or as a protic acid salt and are important intermediates for the manufacture of microbicides for plant protection.

Abstract: The invention relates to compounds of the following general formula I ##STR1## especially the compound of formula Ia referred to as thiangazole ##STR2## their pharmaceutically acceptable acid addition salts, processes for their preparation and therapeutic compositions and compositions that can be used in crop-protection.

Abstract: Compounds of formula I ##STR1## wherein rings A and B are as defined in the specification, have valuable pharmacological properties and are particularly effective as NK1 antagonists and substance P antagonists. Said compounds are prepared in a manner known per se.

Abstract: Stabilisers of formula I ##STR1## wherein R.sub.1 and R.sub.2 may be C.sub.1 -C.sub.5 alkyl, the substituents R.sub.3 to R.sub.8 may be hydrogen, the variable n may be 1 or 2, and, when n is 1, A may be an alkoxy radical, and, when n is 2, A may be a diamine radical.

Abstract: The present invention relates to disperse dyes having the formula ##STR1## wherein X is hydrogen, halogen, C.sub.1 -C.sub.8 alkyl or phenyl which is unsubstituted or substituted by fluoro, chloro, bromo, methyl, methoxy or nitro; Y is cyano, C.sub.1 -C.sub.4 alkoxycarbonyl or nitro; Z is nitro, cyano, acetyl, benzoyl, formyl, --CH.dbd.C(CN).sub.2, --CH.dbd.C(CN)CO.sub.2 R or carbamoyl which is unsubstituted or substituted by C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkyl, phenyl or (C.sub.1 -C.sub.4 alkyl).sub.1-2 phenyl, and R is C.sub.1 -C.sub.4 alkyl, or X and Z or Y and Z are each simultaneously C.sub.1 -C.sub.4 alkoxycarbonyl, and A, B and C are each independently of one another --NH.sub.2 or --N(R.sub.1)R.sub.2, and R.sub.1 and R.sub.2 are each independently of each other hydrogen, phenyl which is unsubstituted or substituted by hydroxy, C.sub.1 -C.sub.4 alkyl, halogen or C.sub.1 -C.sub.4 alkoxy, or is unsubstituted or C.sub.1 -C.sub.