Patents Assigned to Clemson University
  • SURFACE MODIFIED COLLOIDAL PARTICLES
    Publication number: 20130236416
    Abstract: The present invention generally relates to surface modified colloidal particles. The invention further relates to methods of preparing and methods of using the same.
    Type: Application
    Filed: March 7, 2013
    Publication date: September 12, 2013
    Applicant: Clemson University
    Inventors: Parul Rungta, Michael Daniele, JR., Stephen H. Foulger, Ragini Jetty
  • Methods for promoting the revascularization and reenervation of CNS lesions
    Patent number: 8481067
    Abstract: The present invention provides methods of promoting the revascularization and/or reenervation of central nervous system lesions using an in-situ crosslinkable hydrogel.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: July 9, 2013
    Assignee: Clemson University Research Foundation
    Inventors: Ning Zhang, Xuejun Wen
  • System and method for utilizing traffic signal information for improving fuel economy and reducing trip time
    Patent number: 8478500
    Abstract: A system and method for utilizing traffic signal information to reduce wait time at traffic signals and to reduce fuel use is disclosed. Traffic signal timing data can be received from traffic signals or from a central server to determine a reference velocity for a vehicle to travel through a plurality of traffic signals. The reference velocity can then be provided to the driver so that the driver can manually control the vehicle at a velocity close to the reference velocity. The techniques of the present disclosure also can be used in connection with a cruise control system to control the velocity of a vehicle to be close to the reference velocity.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: July 2, 2013
    Assignee: Clemson University
    Inventors: Ardalan Vahidi, Grant David Mahler
  • Method of controlling insect pests in cotton
    Publication number: 20130149723
    Abstract: An assay system is provided in which gossypol is used as a biological marker to detect evolved resistance of insects to Bt cotton. Detection of gossypol using a monoclonal antibody ELISA-based protocol enables at risk populations of insects to be evaluated for evolved resistance to Bt present in a genetically modified cotton. The specificity of the monoclonal antibody to gossypol also enables the production of nanoparticles having a conjugated monoclonal antibody which retains the ability to selectively bind gossypol. Accordingly, nanoparticles can be provided with additional target ligands, such as antibodies, so as to specifically attach to tumors or cancer cells thereby delivering the gossypol to the target cells.
    Type: Application
    Filed: June 14, 2012
    Publication date: June 13, 2013
    Applicant: Clemson University
    Inventors: Xi Wang, Feng Chen
  • Process for forming a hexagonal array
    Patent number: 8453319
    Abstract: The present invention relates to nanopillar arrays that may have relatively large dimensions and relatively large interpillar distances. The present invention also relates to methods of forming the same. In some embodiments of the invention, methods of forming hexagonal nanopillar arrays include forming a base comprising aluminum; forming a hexagonal pattern of pits in the aluminum; anodizing the aluminum to form aluminum oxide comprising a primary hexagonal nanopore array at the positions of the pits in the aluminum; depositing a conductive material into the nanopores of the primary hexagonal nanopore array; and removing the mask and the aluminum oxide to provide the hexagonal nanopillar array.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: June 4, 2013
    Assignee: Clemson University Research Foundation
    Inventor: Guigen Zhang
  • METHODS AND COMPOSITIONS FOR ENHANCED RESISTANCE TO ABIOTIC STRESS IN PLANTS
    Publication number: 20130117882
    Abstract: The present invention provides transgenic plants having increased tolerance to abiotic stress comprising a recombinant nucleic acid molecule, said recombinant nucleic acid molecule comprising a nucleotide sequence encoding miR319 operatively associated with a promoter, a nucleotide sequence that is antisense to a portion of consecutive nucleotides of a nucleotide sequence encoding PCF5, and/or a nucleotide sequence that encodes a portion of consecutive nucleotides of a nucleotide sequence encoding PCF5, which when expressed produces an antisense nucleotide sequence, wherein expression of the nucleotide sequence confers increased tolerance to abiotic stress. Also provided are methods and compositions for making said transgenic plants.
    Type: Application
    Filed: November 8, 2012
    Publication date: May 9, 2013
    Applicant: Clemson University
    Inventor: Clemson University
  • Elastin stabilization of connective tissue
    Patent number: 8435553
    Abstract: A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: May 7, 2013
    Assignee: Clemson University Research Foundation (CURF)
    Inventors: Narendra R. Vyavahare, Jason C. Isenburg, Dan T. Simionescu
  • Ultrahydrophobic substrates
    Patent number: 8389114
    Abstract: Disclosed is a process for modification of a substrate so as to form an ultrahydrophobic surface on the substrate. Also disclosed are surface-modified substrates that can be formed according to the disclosed processes. The process includes attachment of a multitude of nano- and/or submicron-sized structures to a surface to provide increased surface roughness. In addition, the process includes grafting a hydrophobic material to the surface in order to decrease the surface energy and decrease wettability of the surface. The combination of increase surface roughness and decreased surface energy can provide an ultrahydrophobic surface on the treated substrate.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: March 5, 2013
    Assignee: Clemson University
    Inventors: Igor A. Luzinov, Philip J. Brown, Killugudi L. Swaminatha Iyer, Viktor Z. Klep, Bogdan Z. Zdyrko
  • Non-linear electrical actuation and detection
    Patent number: 8384372
    Abstract: A method and system is disclosed to detect and analyze an electric signal based on movement between an element and a counter electrode influenced by a nonlinear electric field produced by an electrical signal impressed between the element and counter electrode. Through detection of changes in the distance between the element and the counter electrode characteristics of the element and/or the environment of the element may be ascertained. Changes in the distance between the element and the counter electrode may be monitored based on changes in the value of capacitance between the element and counter electrode. The disclosed devices and methods may be employed to detect, for instance, presence of chemical/biological species in a sample or measure physical parameters of a sample such as pressure/acceleration, density, viscosity, magnetic force, temperature, and/or extremely small masses.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: February 26, 2013
    Assignee: Clemson University
    Inventors: Herbert W. Behlow, Jr., Bevan C. Elliott, Gayatri D. Keskar, Doyl E. Dickel, Malcolm J. Skove, Apparao M. Rao
  • Vision based real time traffic monitoring
    Patent number: 8379926
    Abstract: A system and method for detecting and tracking one or more vehicles using a system for obtaining two-dimensional visual data depicting traffic flow on a road is disclosed. In one exemplary embodiment, the system and method identifies groups of features for determining traffic data. The features are classified as stable features or unstable features based on whether each feature is on the frontal face of a vehicle close to the road plane. In another exemplary embodiment, the system and method identifies vehicle base fronts as a basis for determining traffic data. In yet another exemplary embodiment, the system and method includes an automatic calibration procedure based on identifying two vanishing points.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: February 19, 2013
    Assignee: Clemson University
    Inventors: Neeraj Krantiveer Kanhere, Stanley T. Birchfield, Wayne A. Sarasua
  • System and method to assess signal similarity with applications to diagnostics and prognostics
    Patent number: 8378816
    Abstract: Signal processing technology for assessing dynamic system similarity for fault detection and other applications is based on time- and frequency-domain time series analysis techniques and compares the entire autocorrelation structure of a test and reference signal series. The test and reference signals are first subjected to similar pre-processing to help guarantee signal stationarity. Pre-processing may include formation of multivariate signal clusters, filtering and sampling. Multivariate periodograms or autocovariance functions are then calculated for each signal series. Test statistics are computed and assessed to determine the equality of the test and reference signals. When the difference between sample autocovariance functions or periodograms of such signals exceeds a preselected threshold value, fault detection signals and/or related diagnostic information are provided as output to a user.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: February 19, 2013
    Assignee: Clemson University
    Inventors: John R. Wagner, Hany F. Bassily, Robert B. Lund
  • INDEX OF REFRACTION MATCHED NANOPARTICLES AND METHODS OF USE
    Publication number: 20130026371
    Abstract: Embodiments of the present disclosure provide for nanoparticles, methods of making nanoparticles, materials including nanoparticles, the use of materials including nanoparticles, and the like.
    Type: Application
    Filed: May 1, 2012
    Publication date: January 31, 2013
    Applicants: CLEMSON UNIVERSITY, UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Paul Howard Holloway, Jihun Choi, Teng-Kuan Tseng, Luiz G. Jacobsohn
  • Method of joining two or more substrates with a seam
    Patent number: 8361582
    Abstract: A method for joining two or more substrates with a seam is provided. The seam is formed with a thermoplastic tape that is capable of forming an adhesive bond and a physical bond with a substrate. For instance, in one embodiment, the thermoplastic tape is formed from a polyurethane film. In addition, the seam can be utilized in a flat configuration or folded into a variety of different shapes, such as in a z-shaped configuration. As a result of the present invention, it has been discovered that a seam can be formed to have improved strength without substantially sacrificing the desired functional properties of the substrate materials.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: January 29, 2013
    Assignee: Clemson University
    Inventors: Christine W Jarvis, Robert E Bennett, Brian Frederick
  • Impedance-based arc fault determination device (IADD) and method
    Patent number: 8362789
    Abstract: Embodiments according to the present invention provide an Impedance-based Arc-Fault Determination Device (IADD) and method that, when attached to an electrical node on the power system and through observations on voltage, current and phase shift with a step load change, determine the effective Thevenin equivalent circuit or Norton equivalent circuit at the point of test. The device and method determine the expected bolted fault current at the test location of interest, which enables calculation of incident energy and the assignment of a flash-hazard risk category.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: January 29, 2013
    Assignees: Clemson University Research Foundation, Duke Energy Carolina, LLC
    Inventors: Edward Randolph Collins, Jr., Timothy Lee Smith, Randall J. Emanuel
  • LITHIUM SALTS OF FLUORINATED BORATE ESTERS FOR LITHIUM-ION BATTERIES
    Publication number: 20120328938
    Abstract: Lithium salts with fluorinated chelated orthoborate anions are prepared and used as electrolytes or electrolyte additives in lithium-ion batteries. The lithium salts have two chelate rings formed by the coordination of two bidentate ligands to a single boron atom. In addition, each chelate ring has two oxygen atoms bonded to one boron atom, methylene groups bonded to the two oxygen atoms, and one or more fluorinated carbon atoms bonded to and forming a cyclic bridge between the methylene groups.
    Type: Application
    Filed: June 21, 2012
    Publication date: December 27, 2012
    Applicants: Clemson University, GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Olt E. Geiculescu, Ion C. Halalay, Darryl D. Desmarteau, Stephen E. Creager
  • Weight control device using bites detection
    Patent number: 8310368
    Abstract: The present invention relates to a device that can be used in individual weight control protocols that is capable of detecting in real time information with regard to number of bites taken, time between bites, and so forth. The weight control device can detect bites through motion detection via a sensor worn on the wrist or hand of a user. The device can include notification capabilities that can alert a user as to excessive eating speed, excessive amounts of food intake, and the like so as to provide immediate feedback for purposes of weight control.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: November 13, 2012
    Assignee: Clemson University Research Foundation
    Inventors: Adam Hoover, Eric Muth, Yujie Dong
  • FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOF
    Publication number: 20120282632
    Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.
    Type: Application
    Filed: November 9, 2010
    Publication date: November 8, 2012
    Applicant: Clemson University
    Inventors: Daniel T. Chiu, Changfeng Wu, Jason McNeill, Jiangbo Yu
  • Semiconductor integrated circuit chip, multilayer chip capacitor and semiconductor integrated circuit chip package
    Patent number: 8304854
    Abstract: Disclosed are a semiconductor integrated circuit chip, a multilayer chip capacitor, and a semiconductor integrated circuit chip package. The semiconductor integrated circuit chip includes a semiconductor integrated circuit chip body, an input/output terminal disposed on the outside of the semiconductor integrated circuit chip body, and a decoupling capacitor disposed at a side face of the semiconductor integrated circuit chip body and electrically connected to the input/output terminal. The semiconductor integrated circuit chip cab be obtained, which can maintain an impedance of a power distribution network below a target impedance in a wide frequency range, particularly at a high frequency, by minimizing an inductance between a decoupling capacitor and a semiconductor integrated circuit chip.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: November 6, 2012
    Assignees: Samsung Electro-Mechanics Co., Ltd., Clemson University
    Inventors: Byoung Hwa Lee, Min Cheol Park, Ho Cheol Kwak, Haixin Ke, Todd Harvey Hubing
  • Three-dimensional ex vivo system
    Patent number: 8293531
    Abstract: Disclosed are three-dimensional (3D) systems as may be utilized for ex vivo tissue or cell growth and development. A system generally includes a base material and at least one wicking fiber embedded therein through which a liquid can be spontaneously drawn by capillary action. Wicking fibers can define a plurality of colinear channels along the exterior surface of the axial length of the fiber. Wicking fibers can be present in disclosed systems as individual fibers or in bundles. Disclosed systems can be useful in various scientific studies, including, but not limited to, drug discovery, vaccine development, cell biology studies, and biomaterial development.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: October 23, 2012
    Assignee: Clemson University Research Foundation
    Inventors: Karen J. L. Burg, Chih-Chao Yang
  • Silicon-Based Anode and Method for Manufacturing the Same
    Publication number: 20120244391
    Abstract: A silicon-based anode comprising silicon, a carbon coating that coats the surface of the silicon, a polyvinyl acid that binds to at least a portion of the silicon, and vinylene carbonate that seals the interface between the silicon and the polyvinyl acid. Because of its properties, polyvinyl acid binders offer improved anode stability, tunable properties, and many other attractive attributes for silicon-based anodes, which enable the anode to withstand silicon cycles of expansion and contraction during charging and discharging.
    Type: Application
    Filed: November 16, 2010
    Publication date: September 27, 2012
    Applicants: Clemson University, Georgia Tech Research Corporation
    Inventors: Gleb Nikolayevich Yushin, Igor Luzinov, Bogdan Zdyrko, Alexandre Magasinski