Patents Assigned to Clemson University
  • Patent number: 7914819
    Abstract: Disclosed are a series of kneadable, pliable polymers for use in forming compositions that can be used as bone wax or as a cellular scaffold. Polymers can include a polysaccharide backbone and can be biocompatible and thrombogenic. In addition, the compositions can be osteoconductive as well as biodegradable. The disclosed compositions can be used to help control bleeding from bone surfaces as well as to promote bone regeneration and fusion. The compositions can inhibit the growth of microorganisms in implantation sites and can be loaded with additional bioactive agents to further promote healing and infection prevention.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: March 29, 2011
    Assignee: Clemson University Research Foundation
    Inventors: Xuejun Wen, Yongzhi Qiu
  • Publication number: 20110049412
    Abstract: Disclosed are photoluminescent particles. The particles include a core nano-sized particle of carbon and a passivation agent bound to the surface of the nanoparticle. The passivation agent can be, for instance, a polymeric material. The passivation agent can also be derivatized for particular applications. For example, the photoluminescent carbon nanoparticles can be derivatized to recognize and bind to a target material, for instance a biologically active material, a pollutant, or a surface receptor on a tissue or cell surface, such as in a tagging or staining protocol.
    Type: Application
    Filed: November 8, 2010
    Publication date: March 3, 2011
    Applicant: CLEMSON UNIVERSITY
    Inventor: Ya-Ping Sun
  • Publication number: 20110048772
    Abstract: Disclosed are conductive polymer inks and methods for forming the inks. The disclosed inks include a dispersion of conductive core/shell nanoparticles. The core/shell nanoparticles include a polymeric core and a shell formed of a conducting polymer. The inks can include a dispersion of the core/shell nanoparticles in a liquid carrier, such as an alcohol. The disclosed inks can be formulated to high viscosities and can be utilized in high-speed printing processes including rotogravure and flexographic printing processes. Products encompassed by the disclosure include polymer devices such as sensors, OFETs, RFID tags, printed circuit board, electrochromic devices, non-volatile memory devices, photovoltaics, and the like.
    Type: Application
    Filed: March 23, 2007
    Publication date: March 3, 2011
    Applicant: CLEMSON UNIVERSITY
    Inventor: Moon Gyu Han
  • Publication number: 20110046982
    Abstract: Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to binding RNA.
    Type: Application
    Filed: August 16, 2010
    Publication date: February 24, 2011
    Applicant: CLEMSON UNIVERSITY RESEARCH FOUNDATION (CURF)
    Inventors: Dev P. Arya, Nihar Ranjan, Sunil Kumar
  • Publication number: 20110014630
    Abstract: Disclosed are photoluminescent particles. The particles include a core nano-sized particle of carbon and a passivation agent bound to the surface of the nanoparticle. The passivation agent can be, for instance, a polymeric material. The passivation agent can also be derivatized for particular applications. For example, the photoluminescent carbon nanoparticles can be derivatized to recognize and bind to a target material, for instance a biologically active material, a pollutant, or a surface receptor on a tissue or cell surface, such as in a tagging or staining protocol.
    Type: Application
    Filed: September 28, 2010
    Publication date: January 20, 2011
    Applicant: CLEMSON UNIVERSITY
    Inventor: Ya-Ping Sun, JR.
  • Patent number: 7871668
    Abstract: The invention is directed to CVD methods and systems that can be utilized to form nanostructures. Exceptionally high product yields can be attained. In addition, the products can be formed with predetermined particle sizes and morphologies and within a very narrow particle size distribution. The systems of the invention include a CVD reactor designed to support the establishment of a convective flow field within the reactor at the expected carrier gas flow rates. In particular, the convective flow field within the reactor can include one or more flow vortices. The disclosed invention can be particularly beneficial for forming improved thermoelectric materials with high values for the figure of merit (ZT).
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: January 18, 2011
    Assignee: Clemson University Research Foundation
    Inventors: Terry M. Tritt, Bo Zhang, Jian He
  • Patent number: 7867985
    Abstract: Fluid compositions and methods for lubrication of mammalian joints are disclosed, including both natural and artificial fluids. Synovial fluid acts to lubricate the bearing surfaces of bones and bone-like structures which are held in frictional contact within biological joints. Such fluids may be used to treat arthritic, injured, and diseased joints. Synovial fluid containing a dextran-based hydrogel with lipids provides enhanced rheological and tribological properties of such a fluid. Phospholipids are particularly useful in dextran-based compositions for synovial fluid. One phospholipid that can be used advantageously in synovial fluid is dipalmitoyl phosphatidylcholine (DPPC).
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: January 11, 2011
    Assignee: Clemson University Research Foundation
    Inventors: Julie-Anne Mason Burdick, Martine Laberge, Gary Lickfield
  • Patent number: 7858677
    Abstract: A composite comprising a first melt processable material referred to as a masterbatch which includes particulate material master batch and a second melt-processable material said first melt processable material and said second melt processable material are formed into a multilayer arrangement by chaotic advection and wherein said particulate material is oriented within layers, or forms networks in said first melt-processable material.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: December 28, 2010
    Assignee: Clemson University
    Inventor: David A Zumbrunnen
  • Publication number: 20100319586
    Abstract: A process of manufacturing cement clinker is provided in which a clean supply of CO2 gas may be captured. The process also involves using an open loop conversion of CaO/MgO from a calciner to capture CO2 from combustion flue gases thereby forming CaCO3/CaMg(CO3)2. The CaCO3/CaMg(CO3)2 is then returned to the calciner where CO2 gas is evolved. The evolved CO2 gas, along with other evolved CO2 gases from the calciner are removed from the calciner. The reactants (CaO/MgO) are feed to a high temperature calciner for control of the clinker production composition.
    Type: Application
    Filed: June 19, 2009
    Publication date: December 23, 2010
    Applicants: Savannah River Nuclear Solutions, LLC, Clemson University
    Inventors: Gerarld C. Blount, Ronald W. Falta, Alvin A. Siddall
  • Patent number: 7849751
    Abstract: The present invention is directed to novel contact sensors. The contact sensors of the invention include a conductive composite material formed of a polymer and a conductive filler. In one particular embodiment, the composite materials can include less than about 10 wt % conductive filler. Thus, the composite material of the contact sensors can have physical characteristics essentially identical to the polymer, while being electrically conductive with the electrical resistance proportional to the load on the sensor. If desired, the sensors can be formed of the same polymeric material as the bearing that is being examined. The sensors can provide real time dynamic contact information for joint members under conditions expected during use. In one particular embodiment, the sensors can be used to examine dynamic wear characteristics of artificial joint bearings such as artificial knee, hip, or shoulder bearings.
    Type: Grant
    Filed: February 15, 2005
    Date of Patent: December 14, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Andrew C. Clark, Martine LaBerge
  • Publication number: 20100307754
    Abstract: An apparatus and process for delivering aerosol-based amendments into a subsurface region is provided. The apparatus used to form the aerosol has an ability to restrict the aerosol particle size to a preferred particle size range such that undesired particle sizes are not introduced. By maintaining a proper ratio of aerosol particle size to subsurface pore size, the efficiency of an aerosol introduction can be enhanced.
    Type: Application
    Filed: June 4, 2010
    Publication date: December 9, 2010
    Applicants: Savannah River Nuclear Solutions, LLC, Clemson University
    Inventors: Brian D. Riha, Lawrence C. Murdoch, Richard J. Hall
  • Publication number: 20100300054
    Abstract: Disclosed are fibrous activated materials that can remove and/or deactivate potentially dangerous airborne agents from a gas or air stream. Disclosed materials are multi-layer materials that include a fibrous nonwoven interceptor layer and an active layer immediately adjacent the interceptor layer. The interceptor layer is a fibrous membrane of very low basis weight and defines a relatively low porosity, and the active layer describes geometries, chemistries, etc. that can entrap and/or decontaminate compounds contained in an airstream passing through the material. Disclosed materials can be utilized in forming protective garments, face masks, and the like.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 2, 2010
    Applicant: Clemson University
    Inventors: Christine W. Cole, Philip J. Brown, Kathryn Stevens, Deborah K. Lickfield
  • Patent number: 7838000
    Abstract: Disclosed are treatment agents and methods of treatment utilizing the agents directed toward diseases in which the disease causing pathogen includes ?6?1 integrin receptors and/or ?6?4 integrin receptors on the surface of the pathogen. In one embodiment, the disease can be breast cancer. The therapeutic agents disclosed include a polypeptide comprising at least a portion of the G domain of the laminin-5 ?3 chain that has been shown to bind ?6?1 integrin receptors and ?6?4 integrin receptors. In one embodiment, the therapeutic agents can be fused or chimeric materials in which the laminin-5 ?3 chain polypeptide has been chemically bound to another material that can be useful in the destruction or neutralization of the pathogen.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: November 23, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Thomas R. Scott, Heather P. Borick, Ginger A. Swire-Clark, William R. Marcotte, Jr., Ashby B. Bodine
  • Patent number: 7834077
    Abstract: The disclosure provides compositions prepared by combining nanomaterials with a halide-containing polymer, thereby forming a combined polymer matrix having dispersed nanomaterials within the matrix. The nanomaterials may be carbon-based nanotubes, in some applications. A halide-containing monomer is combined with nanotubes, and then polymerized in some compositions. In other applications, a halide-containing polymer is solution processed with nanotubes to form useful compositions in the invention. Also disclosed are probes for near field detection of radiation.
    Type: Grant
    Filed: January 3, 2007
    Date of Patent: November 16, 2010
    Assignee: Clemson University Research Foundation
    Inventors: David Carroll, John Ballato, Stephen Foulger, Richard Czerw, Dennis Smith, Hiren Shah, Earl Wagener
  • Patent number: 7828539
    Abstract: Disclosed are methods of forming three dimensional arrays of aligned nanofibers in an open, loose structure of any desired depth. The arrays are formed according to an electrospinning process utilizing two parallel conducting plates to align the fibers and rotating tracks to distribute the fibers throughout the array. Arrays can be used as formed, for instance in tissue engineering applications as three dimensional scaffolding constructs. As-formed arrays can be combined with other materials to form a composite 3-D structure. For instance, composite polymeric materials can be electrospun to form composite nanofibers within the array. Multiple polymeric materials can be electrospun at different areas of the array to form a composite array including materially different nanofibers throughout the array. The arrays can be loaded with other fibrous or non-fibrous materials to form a composite array. Arrays can also be rolled to form a uniaxial fiber bundle.
    Type: Grant
    Filed: March 25, 2008
    Date of Patent: November 9, 2010
    Assignee: Clemson University
    Inventors: Vince Beachley, Xuejun Wen
  • Patent number: 7829772
    Abstract: Disclosed are photoluminescent particles. The particles include a core nano-sized particle of carbon and a passivation agent bound to the surface of the nanoparticle. The passivation agent can be, for instance, a polymeric material. The passivation agent can also be derivatized for particular applications. For example, the photoluminescent carbon nanoparticles can be derivatized to recognize and bind to a target material, for instance a biologically active material, a pollutant, or a surface receptor on a tissue or cell surface, such as in a tagging or staining protocol.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: November 9, 2010
    Assignee: Clemson University Research Foundation
    Inventor: Ya-Ping Sun
  • Patent number: 7818816
    Abstract: Disclosed are methods and devices for patterning micro- and/or nano-sized pattern elements on a substrate using field emitted electrons from an element. Disclosed methods and devices can also be utilized to form nano- and micron-sized depressions in a substrate according to a more economical process than as has been utilized in the past. Methods include single-step methods by which structures can be simultaneously created and located at desired locations on a substrate. Methods include the application of a bias voltage between a probe tip and a substrate held at a relatively close gap distance. The applied voltage can promote current flow between the probe and the substrate via field emissions. During a voltage pulse, and within predetermined energy levels and tip-to-surface gap distances, three dimensional formations can be developed on the substrate surface.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: October 19, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Jason B. Reppert, Jay B. Gaillard, Bevan C. Elliott, Doyl E. Dickel, M. Pinar Mengüc, Apparao M. Rao
  • Patent number: 7785496
    Abstract: Disclosed are electrochromic inks and devices incorporating the inks as well as methods for forming the inks and the devices. The disclosed inks include a dispersion of colloidal nanocomposite particles in a liquid carrier. The colloidal nanocomposites of the disclosed inks include nanoparticle templates, e.g., silica nanoparticles, and an intrinsically conductive polymer polymerized at the template nanoparticles. The inks can include a dispersion of the colloidal nanocomposites in a liquid carrier such as an aprotic polar organic solvent. The disclosed inks can be formulated to be utilized in any desired printing process such as inkjet printing processes. Products encompassed by the invention include all-polymer electronic, optic, photonic, electro-optic, and energy devices such as sensors, OFETs, RFID tags, printed circuit board, electrochromic devices, non-volatile memory devices, photovoltaics, and the like.
    Type: Grant
    Filed: January 24, 2008
    Date of Patent: August 31, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Goo Hwan Shim, Moon Gyu Han, Stephen H. Foulger
  • Publication number: 20100194573
    Abstract: The present invention relates to a device that can be used in individual weight control protocols that is capable of detecting in real time information with regard to number of bites taken, time between bites, and so forth. The weight control device can detect bites through motion detection via a sensor worn on the wrist or hand of a user. The device can include notification capabilities that can alert a user as to excessive eating speed, excessive amounts of food intake, and the like so as to provide immediate feedback for purposes of weight control.
    Type: Application
    Filed: January 13, 2010
    Publication date: August 5, 2010
    Applicant: Clemson University
    Inventors: Adam Hoover, Eric Muth, Yujie Dong
  • Publication number: 20100184170
    Abstract: Disclosed are fermentative enrichment cultures and two pure isolates there from for use in biotransformation of halomethanes. Disclosed bioaugmentation cultures are dominated by Enterobacteriaceae, and are implemented together with one or more electron donors such as corn syrup, glucose, and the like, and a corrinoid catalyst such as vitamin B12. Disclosed cultures and implementation methods can be utilized to transform single halomethanes or mixtures of halomethanes at high rates to non-toxic end products being primarily carbon monoxide, carbon dioxide, and, organic acids.
    Type: Application
    Filed: January 15, 2010
    Publication date: July 22, 2010
    Applicant: CLEMSON UNIVERSITY
    Inventors: Huifeng Shan, David L. Freedman, Harry D. Kurtz, JR.