Patents Assigned to Clemson University
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Patent number: 8378816Abstract: Signal processing technology for assessing dynamic system similarity for fault detection and other applications is based on time- and frequency-domain time series analysis techniques and compares the entire autocorrelation structure of a test and reference signal series. The test and reference signals are first subjected to similar pre-processing to help guarantee signal stationarity. Pre-processing may include formation of multivariate signal clusters, filtering and sampling. Multivariate periodograms or autocovariance functions are then calculated for each signal series. Test statistics are computed and assessed to determine the equality of the test and reference signals. When the difference between sample autocovariance functions or periodograms of such signals exceeds a preselected threshold value, fault detection signals and/or related diagnostic information are provided as output to a user.Type: GrantFiled: July 17, 2008Date of Patent: February 19, 2013Assignee: Clemson UniversityInventors: John R. Wagner, Hany F. Bassily, Robert B. Lund
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Publication number: 20130026371Abstract: Embodiments of the present disclosure provide for nanoparticles, methods of making nanoparticles, materials including nanoparticles, the use of materials including nanoparticles, and the like.Type: ApplicationFiled: May 1, 2012Publication date: January 31, 2013Applicants: CLEMSON UNIVERSITY, UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.Inventors: Paul Howard Holloway, Jihun Choi, Teng-Kuan Tseng, Luiz G. Jacobsohn
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Patent number: 8361582Abstract: A method for joining two or more substrates with a seam is provided. The seam is formed with a thermoplastic tape that is capable of forming an adhesive bond and a physical bond with a substrate. For instance, in one embodiment, the thermoplastic tape is formed from a polyurethane film. In addition, the seam can be utilized in a flat configuration or folded into a variety of different shapes, such as in a z-shaped configuration. As a result of the present invention, it has been discovered that a seam can be formed to have improved strength without substantially sacrificing the desired functional properties of the substrate materials.Type: GrantFiled: October 31, 2007Date of Patent: January 29, 2013Assignee: Clemson UniversityInventors: Christine W Jarvis, Robert E Bennett, Brian Frederick
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Patent number: 8362789Abstract: Embodiments according to the present invention provide an Impedance-based Arc-Fault Determination Device (IADD) and method that, when attached to an electrical node on the power system and through observations on voltage, current and phase shift with a step load change, determine the effective Thevenin equivalent circuit or Norton equivalent circuit at the point of test. The device and method determine the expected bolted fault current at the test location of interest, which enables calculation of incident energy and the assignment of a flash-hazard risk category.Type: GrantFiled: October 2, 2009Date of Patent: January 29, 2013Assignees: Clemson University Research Foundation, Duke Energy Carolina, LLCInventors: Edward Randolph Collins, Jr., Timothy Lee Smith, Randall J. Emanuel
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Publication number: 20120328938Abstract: Lithium salts with fluorinated chelated orthoborate anions are prepared and used as electrolytes or electrolyte additives in lithium-ion batteries. The lithium salts have two chelate rings formed by the coordination of two bidentate ligands to a single boron atom. In addition, each chelate ring has two oxygen atoms bonded to one boron atom, methylene groups bonded to the two oxygen atoms, and one or more fluorinated carbon atoms bonded to and forming a cyclic bridge between the methylene groups.Type: ApplicationFiled: June 21, 2012Publication date: December 27, 2012Applicants: Clemson University, GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Olt E. Geiculescu, Ion C. Halalay, Darryl D. Desmarteau, Stephen E. Creager
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Patent number: 8310368Abstract: The present invention relates to a device that can be used in individual weight control protocols that is capable of detecting in real time information with regard to number of bites taken, time between bites, and so forth. The weight control device can detect bites through motion detection via a sensor worn on the wrist or hand of a user. The device can include notification capabilities that can alert a user as to excessive eating speed, excessive amounts of food intake, and the like so as to provide immediate feedback for purposes of weight control.Type: GrantFiled: January 13, 2010Date of Patent: November 13, 2012Assignee: Clemson University Research FoundationInventors: Adam Hoover, Eric Muth, Yujie Dong
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Publication number: 20120282632Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.Type: ApplicationFiled: November 9, 2010Publication date: November 8, 2012Applicant: Clemson UniversityInventors: Daniel T. Chiu, Changfeng Wu, Jason McNeill, Jiangbo Yu
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Patent number: 8304854Abstract: Disclosed are a semiconductor integrated circuit chip, a multilayer chip capacitor, and a semiconductor integrated circuit chip package. The semiconductor integrated circuit chip includes a semiconductor integrated circuit chip body, an input/output terminal disposed on the outside of the semiconductor integrated circuit chip body, and a decoupling capacitor disposed at a side face of the semiconductor integrated circuit chip body and electrically connected to the input/output terminal. The semiconductor integrated circuit chip cab be obtained, which can maintain an impedance of a power distribution network below a target impedance in a wide frequency range, particularly at a high frequency, by minimizing an inductance between a decoupling capacitor and a semiconductor integrated circuit chip.Type: GrantFiled: November 13, 2008Date of Patent: November 6, 2012Assignees: Samsung Electro-Mechanics Co., Ltd., Clemson UniversityInventors: Byoung Hwa Lee, Min Cheol Park, Ho Cheol Kwak, Haixin Ke, Todd Harvey Hubing
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Patent number: 8293531Abstract: Disclosed are three-dimensional (3D) systems as may be utilized for ex vivo tissue or cell growth and development. A system generally includes a base material and at least one wicking fiber embedded therein through which a liquid can be spontaneously drawn by capillary action. Wicking fibers can define a plurality of colinear channels along the exterior surface of the axial length of the fiber. Wicking fibers can be present in disclosed systems as individual fibers or in bundles. Disclosed systems can be useful in various scientific studies, including, but not limited to, drug discovery, vaccine development, cell biology studies, and biomaterial development.Type: GrantFiled: August 29, 2008Date of Patent: October 23, 2012Assignee: Clemson University Research FoundationInventors: Karen J. L. Burg, Chih-Chao Yang
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Publication number: 20120244391Abstract: A silicon-based anode comprising silicon, a carbon coating that coats the surface of the silicon, a polyvinyl acid that binds to at least a portion of the silicon, and vinylene carbonate that seals the interface between the silicon and the polyvinyl acid. Because of its properties, polyvinyl acid binders offer improved anode stability, tunable properties, and many other attractive attributes for silicon-based anodes, which enable the anode to withstand silicon cycles of expansion and contraction during charging and discharging.Type: ApplicationFiled: November 16, 2010Publication date: September 27, 2012Applicants: Clemson University, Georgia Tech Research CorporationInventors: Gleb Nikolayevich Yushin, Igor Luzinov, Bogdan Zdyrko, Alexandre Magasinski
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Patent number: 8237015Abstract: The present invention is directed to the use of multiple site-specific recombination systems for use in transgene containment in plants. More specifically, the present invention describes coordinated excisional DNA recombination by multiple (e.g., dual) recombinases to achieve excision of unwanted transgenic DNA as well as recombinase-coding sequences themselves by self-excision. Further, the simultaneous use of multiple site-specific recombination systems in combination with controllable total sterility technology (i.e., no or reduced sexual reproduction), provides the production of environmentally safe, clean transgenic plants, enhancing the capability and public acceptance of transgenic technology for plant trait modification.Type: GrantFiled: July 16, 2008Date of Patent: August 7, 2012Assignee: Clemson University Research FoundationInventor: Hong Luo
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Patent number: 8226850Abstract: An oxygen scavenging system comprising a free radical scavenger (e.g., ?-tocopherol, trimethylhydroquinone, ubiquinol, carotenoids, flavonoids, etc. and mixtures thereof) and a transition metal (e.g., iron (II), copper, manganese, cobalt, etc. and mixtures thereof) in a medium is generally provided. The medium containing the antioxidant and the transition metal has been thermally processed by heating to at least about 150° F. for at least about 10 minutes. Methods of removing oxygen from an environment surrounded by a medium containing the oxygen scavenging system and methods of making the oxygen scavenging system in a medium are also provided.Type: GrantFiled: September 22, 2009Date of Patent: July 24, 2012Assignee: Clemson University Research FoundationInventors: Youngjae Byun, William S. Whiteside
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Patent number: 8217161Abstract: The present invention relates to siRNAs that are targeted to RNAs encoding two or more enzymes of a subfamily of cytochrome P450 (CYP) enzymes, along with vectors, cells, and kits comprising the siRNAs. The invention further relates to methods of decreasing expression of two or more CYP subfamily genes in a non-human animal, animals in which expression of two or more CYP subfamily genes has been decreased, and methods of using such animals to study the function of cytochrome P450 enzymes.Type: GrantFiled: April 22, 2009Date of Patent: July 10, 2012Assignee: Clemson University Research FoundationInventor: William S. Baldwin
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Patent number: 8148559Abstract: Disclosed are processes for development and recovery of lipids from biomass. A plant or microorganism-based biomass can be developed to encourage a desired lipid profile. Following development, ecologically friendly normally gaseous fluids such as carbon dioxide can be pressurized to a supercritical state followed by rapid expansion. The fluid is first contacted with a biomass source including oil-containing microorganisms and/or agricultural products. For instance, fungi or algae can be bioconverted from another biomass sources such as canola seed or corn syrup and then contacted with the high pressure fluid. During a contact period, the fluid can diffuse into the biomass, and in particular through the cell walls of the biomass. The fluid undergoes rapid release of pressure and opens the cell structure for improved release of oil. The fluid can optionally be utilized for extraction following the explosion process. For instance, the fluid can be re-pressurized in the same vessel for extraction processes.Type: GrantFiled: August 28, 2008Date of Patent: April 3, 2012Assignee: Clemson University Research FoundationInventors: Terry H. Walker, Meidui Dong, Keri B. Cantrell, Mark C. Thies
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Patent number: 8148120Abstract: Disclosed are methods that can advantageously utilize the natural consumptive and conversion processes of an aquatic organism culture system to concentrate and separate microbial plant-generated lipids. For instance, an aquatic organism culture can be maintained and/or grown upon an algal biomass. The natural conversion processes of the animals allows for uptake and processing of the components of the algal biomass into animal lipid. The aquatic animal culture can then be easily harvested such that a high percentage of the converted algal-generated lipid can be extracted using a low cost, simple and quick process. The disclosed processes provide an efficient oil production, conversion and recovery system that can be economically scaled up for use in, for example, integrated bioenergy and biodiesel production.Type: GrantFiled: March 28, 2008Date of Patent: April 3, 2012Assignee: Clemson University Research FoundationInventors: Lance Beecher, David E. Brune
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Patent number: 8149039Abstract: A picosecond pulse generator apparatus and methodology is disclosed. A pulse generator is provided by forming a transmission line and a switching element on a common semiconductor substrate or semiconductor chip. The transmission line and the switching element can be provided on the common CMOS semiconductor substrate using standard CMOS technology. A voltage is applied to the transmission line to charge the transmission line. An input pulse is applied to the switching device to trigger the switching device to cause the transmission line to discharge an output pulse across a load resistor. The pulse width of the output pulse depends in major part on the length of the transmission line. Additional components can be provided on the common semiconductor substrate or chip to shape the input pulse to the switching device to ensure a fast rise time.Type: GrantFiled: September 30, 2009Date of Patent: April 3, 2012Assignee: Clemson UniversityInventors: Pingshan Wang, Chaojiang Li
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Patent number: 8142805Abstract: Disclosed are implantable tissues including one or more enzyme inhibitors bound in the tissues, bioprostheses including the tissue, and methods for incorporating enzyme inhibitors in implantable tissues. Disclosed tissue can exhibit increased resistance to degradation, and specifically, degradation due to enzyme activity following implantation. Moreover, the disclosed methods can lead to increased levels of beneficial components bound in implantable tissues following a fixation/stabilization protocol. Increased levels of beneficial agents in an implantable tissue can further improve the implantable tissues and bioprostheses incorporating the tissues through improved mechanical characteristics and longer lifespan.Type: GrantFiled: November 5, 2007Date of Patent: March 27, 2012Assignee: Clemson University Research FoundationInventors: Narendra R. Vyavahare, Devanathan Raghavan
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Patent number: 8133740Abstract: Disclosed are methods, materials and systems that can be used to determine qualitatively or quantitatively the level of uranium contamination in water samples. Beneficially, disclosed systems are relatively simple and cost-effective. For example, disclosed systems can be utilized by consumers having little or no training in chemical analysis techniques. Methods generally include a concentration step and a complexation step. Uranium concentration can be carried out according to an extraction chromatographic process and complexation can chemically bind uranium with a detectable substance such that the formed substance is visually detectable. Methods can detect uranium contamination down to levels even below the MCL as established by the EPA.Type: GrantFiled: August 19, 2009Date of Patent: March 13, 2012Assignees: Clemson University Research Foundation, Savannah River Nuclear Solutions, LLCInventors: Timothy A. DeVol, Amy E. Hixon, David P. DiPrete
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Patent number: 8128952Abstract: Disclosed are systems and methods that can be utilized to define and control the delivery rate of a biological agent from a carrier matrix such as a biocompatible hydrogel. The carrier matrices of the present invention can include ligands incorporated within the matrix at a predetermined concentration level (CLT). In addition, the ligands within the matrix can display a particular, predetermined affinity for the biologically active agents to be delivered by the system. In particular, the affinity between the ligand and the biologically active agent can have a known predetermined dissociation constant (KD). When utilizing the system, the agent can be incorporated within the matrix due to association of the agent with the ligand. In addition, the agent can be protected from side reactions due to the association of the agent with the ligand. Through particular selection of the parameters CLT and KD, the rate of release of the biologically active agent from the matrix can be controlled.Type: GrantFiled: January 12, 2005Date of Patent: March 6, 2012Assignee: Clemson University Research FoundationInventors: Andrew T. Metters, Srinivas Chollangi
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Patent number: 8128835Abstract: A deicing composition is provided. The composition includes a potassium or sodium salt of a carboxylic acid and a lithium salt of a carboxylic acid or lithium nitrate, wherein the molar ratio of lithium to potassium or lithium to sodium is from 10 percent to 80 percent.Type: GrantFiled: April 8, 2011Date of Patent: March 6, 2012Assignees: FMC Corporation, Lithium Division, Clemson UniversityInventors: David B. Stokes, Daniel Person Johnston, Prasada Rao Rangaraju, Vijay C. Mehta, Claudio E. Manissero