Abstract: Methods for obtaining purified lignin and the lignin that can be obtained by the methods are described. Methods include processing pretreated lignocellulosic biomass feedstock to recover the lignin and provide a lignin composition with a very low level of impurities such as metals and ash. In addition, the lignin recovered from the process can have a narrow molecular weight distribution and, depending upon the specific stages utilized in the process, can have a predetermined molecular weight. The process includes one or more separation stages in which a lignin-containing feedstock is mixed with a solvent solution. The mixture fractionates to form a solvent-rich liquid phase and a lignin-rich liquid phase, the lignin being partitioned across the phases according to the molecular weight of the lignin. Furthermore, the metal salts of the pretreated lignocellulosic biomass feedstock also partition across the phases.
Type:
Grant
Filed:
November 19, 2015
Date of Patent:
August 21, 2018
Assignee:
Clemson University
Inventors:
Mark C. Thies, Adam S. Klett, David A. Bruce
Abstract: A plant propagation system is described that can be utilized for micropropagation through early stages of plant development. A system can include multiple plant support matrices, containers for the matrices, and optionally a tool for separating sections of a plant support matrix from the remainder of the matrix. During use developing plant tissue can be transferred between matrices and growth media can be varied with little or no damage to developing plant tissue and lower chances for contamination of the developing plant tissues.
Type:
Application
Filed:
June 2, 2016
Publication date:
July 26, 2018
Applicants:
Pioneer Hi-Bred International, Inc., Clemson University
Inventors:
Jeffrey Adelberg, Amber E. Heck, David Dallinger Kurth, Justine M. Olszewski
Abstract: A silicon-based anode comprises an alginate-containing binder. The many carboxy groups of alginate bind to a surface of silicon, creating strong, rigid hydrogen bonds that withstand battery cycling. The alginate-containing binder provides good performance to the anode by (1) improving the capacity of the anode in comparison to other commercially-available binders, (2) improving Columbonic efficiency during charging and discharging cycles, and (3) improving stability during charging and discharging cycles.
Type:
Grant
Filed:
January 8, 2014
Date of Patent:
July 17, 2018
Assignees:
Georgia Tech Research Corporation, Clemson University Research Foundation
Inventors:
Gleb Yushin, Igor Luzinov, Bogdan Zdyrko, Oleksandr Magazynskyy, Igor Kovalenko
Abstract: Methods and systems for preventing biofouling of membranes utilized in water treatment processes (i.e., water treatment membranes) are described. Methods include X-ray excitation of luminescent materials capable of emitting in the violet to UV range (e.g., from about 180 nm to about 440 nm). X-rays are directed at water treatment modules to contact the luminescent materials within the modules and excite internal violet/UV to prevent biofouling of membranes. The methods can be utilized in conjunction with existing processing equipment and can prevent biofouling of water treatment membranes in high volume treatment processes in an environmentally friendly fashion.
Abstract: Tissue holders that can be used for gripping natural or synthetic heart valves are described. The tissue holder can include a clamping mechanism and a spring and can be self-adjusting with regard to pressure applied to the tissue gripped in the holder. The tissue holder can be removably attached to systems for processing the tissues and can provide completely hands-free processing of a tissue from development or excisement to implantation and/or completion of testing.
Type:
Grant
Filed:
July 23, 2015
Date of Patent:
July 17, 2018
Assignee:
CLEMSON UNIVERSITY RESEARCH FOUNDATION
Inventors:
Leslie Sierad, Richard Pascal, Christopher deBorde, Dan Simionescu, Agneta Simionescu
Abstract: The present invention provides transgenic plants having increased tolerance to cold and altered flowering characteristics. Also provided are methods and compositions for producing said transgenic plants.
Type:
Grant
Filed:
October 14, 2015
Date of Patent:
July 17, 2018
Assignee:
Clemson University
Inventors:
Hong Luo, Shauangrong Yuan, Zhigang Li, Qian Hu
Abstract: Methods and devices for automated adjustment of a digging implement during harvest of underground crops are described. Utilizing the devices, a digging implement, e.g., a blade, can be located and maintained at a desired depth as a harvester travels across a field. During use, the digging implement depth controls can be varied as the harvester travels within a single field under different operating conditions, e.g., different soil friability, consistency, etc., thereby preventing crop loss and improving crop yield.
Type:
Grant
Filed:
July 14, 2016
Date of Patent:
May 15, 2018
Assignee:
Clemson University
Inventors:
Kendall R. Kirk, J. Warren White, Joel S. Peele, W. Scott Monfort, Hunter F. Massey, James S. Thomas, Stanley A. Brantley, Andrew C. Warner
Abstract: Invention is directed to a method of extruding an omni-phobic filament comprising: extruding a co-polymer filament having a first polymer at a core having generally a circular cross-section, and a second polymer disposed at a perimeter of the core wherein the second polymer is dissolvable; creating channels disposed at the perimeter of the core by dissolving the second polymer; creating trapezoidal cross-section features having a distal angle less than 70°, a top edge greater than a side length and a bottom length less than the side length; and adding nano-sized particles to at least one of the top edge and one or more sides or any combination thereof.
Type:
Application
Filed:
October 27, 2017
Publication date:
May 3, 2018
Applicants:
Clemson University Research Foundation, The United States Department of Defense Department of the Army
Inventors:
Philip Brown, Quoc Tien Truong, Nicole Hoffman
Abstract: The present invention provides methods and compositions for regulation of gene expression in plants. In particular, the invention provides nucleic acids that can confer tissue specific and constitutive expression to operably linked polynucleotides of interest.
Abstract: Yield monitoring systems for harvesting machines and methods that can provide yield monitoring of crops are described. Machines include those that pneumatically convey crop through the machine such as peanut harvesting machines. The yield monitoring system includes a force sensor that can be located in conjunction with a duct of the harvesting machine such that impact of the crop materials on an impact plate within the duct will be registered by the force sensor. This registration can be used to determine a mass flow rate for the crop, which can be correlated to yield of the crop. The systems can include additional components such as optical monitors, moisture sensors, and pressure sensors.
Type:
Grant
Filed:
July 9, 2015
Date of Patent:
May 1, 2018
Assignee:
Clemson University
Inventors:
Kendall R. Kirk, J. Warren White, W. Scott Monfort, Hunter F. Massey, D. Hollens Free, Stanley A. Brantley, Joel S. Peele, Jacob B. Fravel, William G. Henderson, Jr.
Abstract: The present invention provides transgenic plants having increased tolerance to abiotic stress comprising a recombinant nucleic acid molecule, said recombinant nucleic acid molecule comprising a nucleotide sequence encoding miR319 operatively associated with a promoter, a nucleotide sequence that is antisense to a portion of consecutive nucleotides of a nucleotide sequence encoding PCF5, and/or a nucleotide sequence that encodes a portion of consecutive nucleotides of a nucleotide sequence encoding PCF5, which when expressed produces an antisense nucleotide sequence, wherein expression of the nucleotide sequence confers increased tolerance to abiotic stress. Also provided are methods and compositions for making said transgenic plants.
Abstract: Illustrative embodiments of microdevices and methods of manufacturing such microdevices are disclosed. In at least one illustrative embodiment, one or more microdevices may be formed on a substrate, with each of the one or more microdevices comprising a body micromachined from a continuous film formed on the substrate, the continuous film having a controlled microstructure of cellulose nanocrystals (CNC).
Type:
Grant
Filed:
May 1, 2016
Date of Patent:
February 13, 2018
Assignees:
Auburn University, Clemson University
Inventors:
William Robert Ashurst, Virginia A. Davis, Christopher L. Kitchens
Abstract: Disclosed are methods for forming ammonia and ammonium that can be utilized in certifiably organic farming productions according to most if not all known certification standards. Also disclosed are bioreactors that can be utilized in carrying out disclosed methods. Methods and systems utilize obligate anaerobic bacteria to breakdown organic protein substrates, i.e., compounds containing bound nitrogen, to provide nitrogen in an unbound plant available form, and particularly, ammonia and/or ammonium. Obligate anaerobic bacteria include high ammonia producing bacteria such as Peptostreptococcus anaerobius, Clostridium sticklandii, and Clostridium aminophilum.
Abstract: A solid phase for use in separation has been modified using an aqueous phase adsorption of a headgroup-modified lipid to generate analyte specific surfaces for use as a stationary phase in separations such as high performance liquid chromatography (HPLC) or solid phase extraction (SPE). The aliphatic moiety of the lipid adsorbs strongly to a hydrophobic solid surface, with the hydrophilic and active headgroups orienting themselves toward the more polar mobile phase, thus allowing for interactions with the desired solutes. The surface modification approach is generally applicable to a diversity of selective immobilization applications such as protein immobilization clinical diagnostics and preparative scale HPLC as demonstrated on capillary-channeled fibers, though the general methodology could be implemented on any hydrophobic solid support material.
Type:
Grant
Filed:
July 17, 2014
Date of Patent:
November 28, 2017
Assignee:
Clemson University
Inventors:
R. Kenneth Marcus, Kenneth A. Christensen
Abstract: A multi-step stabilization method for connective tissue is described. Stabilized tissues can exhibit increased resistance to degradation due to enzyme activity, fatigue and storage. The multi-step method includes a first step during which the tissue can be incubated with a glycosaminoglycanase inhibitor such as a sulfated oligosaccharide, one example of which being neomycin, a second step during which the tissue can be incubated with a crosslink activator such as a carbodiimide crosslink activator and/or a crosslinking agent such as a heterobifunctional crosslinking agent and/or a phenolic compound such as a tannin, examples of which include tannic acid and pentagalloylglucose, and a third step during which the tissue can be incubated with a second crosslink activator that can be the same or different as the first crosslink activator.
Abstract: A system and method for modeling, controlling and analyzing electrical grids for use by control room operators and automatic control provides a multi-dimensional, multi-layer cellular computational network (CCN) comprising an information layer; a knowledge layer; a decision-making layer; and an action layer; wherein each said layer of said CCN represents one of a variable in an electric power system. Situational awareness/situational intelligence is provided therefrom so that the operators and grid control systems can make the correct decision and take informed actions under difficult circumstances to maintain a high degree of grid integrity and reliability by analyzing multiple variables within a volume of time and space to provide an understanding of their meaning and predict their states in the near future where these multiple variables can have different timescales.
Abstract: Disclosed are systems, compositions, and methods for three-dimensional (3D) printing. An example system includes a plurality dispensers configured to deposit materials from their tips and a printing surface for receiving the materials. The system includes a position sensing detector configured to detect positions of the tips of the dispensers and the location and dimensions of the printing surface. The system includes a robotic positioning device configured to drive the dispensers. The system also includes a control unit configured to receive and map in a 3D space the positions of the tips of the dispensers and the position and dimensions of the printing surface. The control unit is further configured to control the robotic positioning device to drive the dispensers relative to the printing surface in the 3D space, and to independently deposit materials on the printing surface, or on material deposited on the printing surface.
Type:
Grant
Filed:
May 1, 2015
Date of Patent:
September 19, 2017
Assignees:
MUSC Foundation for Research Development, Izumi International, Inc., Clemson University
Inventors:
Michael J. Yost, Thomas Trusk, Ying Mei, Michael Chappell, Walter Boylan
Abstract: Methods for forming a nanoparticle assembly are generally provided. The method can comprise applying a colloidal fluid to a surface of a magnetic media, wherein the colloidal fluid comprises magnetic nanoparticles, a surfactant, a trigger salt, and a carrier medium; and assembling the magnetic nanoparticles into a pattern through a magnetic force arising from the surface of the magnetic media.
Type:
Grant
Filed:
November 7, 2014
Date of Patent:
September 19, 2017
Assignees:
University of South Carolina, Clemson University
Inventors:
Thomas M. Crawford, Longfei Ye, Tanner G. Pearson, O. Thompson Mefford, Yves Cordeau