Abstract: The present application relates to an anti-counterfeiting object including a face with an optical identification marking which is readable by the eye and/or by a machine, and an authentication volume, the authentication volume extending from the face in the thickness (z) direction so as to be accessible from the face in order to be read by X-ray diffractometry (XRD). The authentication volume is a composite of a first material, referred to as the authentication material, and at least one second material, the authentication volume constituting a material volume of at least 5 mm3. The authentication material includes at least one amorphous phase, at least one crystalline phase and at least one complex metal phase. The second material is typically a polymer. The application may advantageously be implemented by 3D printing.

Abstract: An assembly for detecting volatile compounds in a gaseous fluid includes a detector for detecting vapours, equipped with a suction tube, and a vapour-sampling optimisation device. This vapour-sampling optimisation device has an end piece with a body having a through-passage extending along an axis in a suction direction and configured to accept the suction tube. The device also has a fluidic network with an inlet in fluidic communication with at least one outlet. When the gaseous fluid is injected into the end piece via the inlet of the fluidic network, the network forms a jet of gaseous fluid which is ejected from the end piece on either side of the suction direction. Each jet forms an angle of 10° to 90° in absolute value with the axis of the suction direction, so that the jet ejected from the end piece moves away from the suction axis.

Abstract: The present disclosure relates to injectable or implantable compositions that are able to mimic different types of mineralized biological tissues and their uses in mineralized tissues repair and regeneration.

Abstract: A catalytic material comprising at least one group VIB metal at least partly in sulfide form, at least one group IVB metal at least partly in sulfide form, and an electrically conductive support wherein said group VIB metal is chosen from molybdenum and/or tungsten, said group IVB metal is chosen from titanium, zirconium and/or hafnium.

Abstract: The present invention relates to regulatory T cell and uses thereof. By their immunosuppressive and anti-inflammatory activities, regulatory T cells play a central role in peripheral tolerance and thus critically prevent the development of autoimmune and inflammatory disorders. The inventors showed that Foxp3+CD4+ Tregs express high levels of LT?, which negatively regulates their immunosuppressive signature. They demonstrated that the adoptive transfer of LT??/? Tregs in mice protects from dextran sodium sulfate (DSS)-induced colitis and attenuates inflammatory bowel disease (IBD), multi-organ autoimmunity and the development of CAC. The inventors also showed that by mixed bone marrow chimeras that LT? expression specifically in hematopoietic cells negatively controls the immunosuppressive signature of Tregs. In particular, the present invention relates to regulatory T cell characterized in that it does not express or expresses reduced levels of lymphotoxin alpha.

Abstract: Methods and systems are provided for decoding movement intentions using functional ultrasound (fUS) imaging of the brain. In one example, decoding movement intentions include determining a memory phase of a cognitive state of the brain, the memory phase between a gaze fixation phase and movement execution phase, and determining one or more movement intentions including one or more of intended effector (e.g., hand, eye) and intended direction (e.g., right, left) according to a machine learning algorithm trained to classify one or more movement intentions simultaneously.

Abstract: A device positioning an object according to a given direction, including a frame, a holder for holding the object, the holder being movable relative to the frame according to the given direction, a main lever extending between a first point and a second point, said main lever being rotatably mounted to the frame via a first pivot link connecting the main lever and the frame at the first point of the main lever, the main lever being connected to the holder at a third point which is arranged between the first point and the second point, so that a displacement of the second point of the main lever relative to the frame according to the given direction causes displacement of the holder in said given direction.

Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.

Abstract: The invention relates to a measuring device (10) for measuring physical characteristics of cells. The device (10) comprises: a microfluidic chip (20) provided with a flow channel (22) for allowing cells to flow through; a manipulator (24) configured to apply deformation force to a cell in a continuous flow; and a sensor (26) configured to sense a physical characteristic of the cell. The manipulator (24) and the sensor (26) are configured to define a width (W2) of the flow channel (22) as a gap formed between them. The manipulator (24) is configured to apply the deformation force to the cell by compressing the cell against the sensor (26).

Abstract: The present invention relates to a chimeric protein comprising at least one human amyloid P component and at least one fragment of an Fc region of a human antibody, the human amyloid P component and the fragment of an Fc region with which it is associated being bound to each other by means of a hinge region.

Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.

Abstract: An optical device suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum. The device comprises at least a first coating layer made of a first material, a substrate made of a material different from the first material, and surface texturing forming cavities in the device. A lower layer, disposed directly below the first coating layer, is either a second coating layer made of a material different from the first material or the substrate itself. The lower layer has a predetermined thickness. The optical device has cavities that extend through the first coating layer and are sunk into the lower layer through at least part of its thickness. This structure enhances the optical properties of the device for specific applications in electromagnetic radiation transmission or reflection.

Abstract: The present invention relates to diltiazem for use as an agent for activating the expression of at least one gene encoding a type III interferon, in the prevention and/or treatment of infections by at least one pathogenic microorganism of the epithelia of the respiratory and/or intestinal tracts.

Abstract: Process of grafting of a polyethylene-containing material to produce a modified polyethylene composition comprising providing a twin screw extruder with one or more thermal regulation devices; a polyethylene-containing material and a grafting agent and extruding the polyethylene-containing material and the grafting agent to obtain a modified polyethylene composition; the step of extruding comprises a thermal treatment of the polyethylene-containing material by self-heating of the material at a maximum barrel temperature Ts ranging from 315° C. to 410° C. in one or more hot zones of the extruder.

Abstract: The present invention relates to a process and a system for the production of hydrogen and carbon by catalytic non-oxidative decomposition of hydrocarbons, such as saturated C1+ hydrocarbons, such as methane, in the presence of a fresh or a spent catalyst composition comprising at least one carbon catalyst. The process of the invention is characterised in that the fresh or spent catalyst composition is heated by means of induction heating to a temperature comprised between 500° C. and 1100° C. The catalyst compositions as applied in accordance with the invention comprise, and preferably consist of, (I) a first component, wherein said first component is selected from one or more non-porous carbon catalysts and/or one or more porous carbon catalysts; and (II) optionally, a second component, wherein said second component consists of a non-carbon material, and preferably is a ceramic or zeolitic support material.

Abstract: The present invention relates to compounds of formula (I): for use as peripheral NMDA receptor antagonists.

Abstract: Disclosed is a method for producing, in one step, “made to measure” double-stranded DNA vectors from molecular bricks including sequences of interest in the presence of a one and only type IIs restriction enzyme.

Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.

Abstract: The present invention relates to a method for producing a colloid comprising functionalised liquid colloidal particles. The invention also relates to such a colloid and to the uses thereof.

Abstract: Disclosed are chelates resulting from the complexation of bifunctional do2pa derivatives ligands of formula (I), wherein the substituents R1, R1?, R2, R2?, R3, R3?, L1, L1?, L2 and L2? are defined as in the claims, with metallic cations, especially Pb(II) and Bi(III). Also disclosed are bifunctional do2pa derivatives ligands of formula (I), as well as the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents.