Patents Assigned to CNRS
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Publication number: 20250006915Abstract: A process for preparing a compound of formula (NaOH)x[Fe(OH)2]yFeS, may include: (a) mixing iron and sodium sulfide in equimolar amounts, in an NaOH aqueous solution; (b) heating the obtained mixture up to a temperature in a range of from 110 to 210° C. for a duration in a range of from 1 hour to 1 week; and (c) recovering the active material by filtering and drying in a neutral atmosphere.Type: ApplicationFiled: September 21, 2022Publication date: January 2, 2025Applicants: AMPERE S.A.S., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Ecole Nationale Supérieure de Chimie de ParisInventors: Philippe BARBOUX, Mohamed CHAKIR, Domitille GIAUME, Ine HAUGLAND-GOSLING, Caroline MIR
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Publication number: 20250000428Abstract: A computer-implemented method for assisting a general anesthesia or a sedation of a subject, having receiving an electroencephalogram EEG signal of a subject, processing the EEG signal including ?-bands for defining for each instant of a plurality of instants, a part of the signal has in a time window having the instant, the part of the signal being related to the instant, determining for each instant, a distribution of a power of the part of the signal as a function of the frequency, determining for each instant a maximum power frequency as a frequency of maximum power in the distribution, the maximum power frequency being related to the instant, detecting a reference instant, so that the maximum power frequency as a function of time takes higher values before the reference instant than after, detecting in a time frame following the reference instant, an alpha instant corresponding to a first occurrence of a suppression of an ?-band, estimating a first parameter as the duration between the reference instType: ApplicationFiled: July 26, 2022Publication date: January 2, 2025Applicants: PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, NATIONAL INSTITUTE OF HEALTH AND MEDICAL RESEARCH, ASSISTANCE PUBLIQUE HÔPITAUX DE PARISInventors: David HOLCMAN, Matteo DORA, Christophe SUN
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Publication number: 20250003980Abstract: Identification of at least one microorganism present in a sample based on the detection of peptides issued from the cleavage of ribosomal proteins of said microorganism, comprising lysis of microorganism(s) and cleavage of the proteins, obtaining a mixture of peptides, decomplexing the peptide mixture using a liquid separation device coupled with a mass spectrometer, nebulizing the liquid to produce an ion current, receiving the ion current from the ion source, executing on the ion current a series of filtering steps for detecting a transition, receiving data on the transitions, assigning the transitions associated with peptides into two or more contiguous groups, monitoring, and optionally generating a chromatogram or electropherogram, wherein the microorganism is identified according to the detection of said peptide(s).Type: ApplicationFiled: July 15, 2022Publication date: January 2, 2025Applicants: Université Claude Bernard Lyon 1, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Ecole Normale Superieure de Lyon, Hospices Civils de LyonInventors: Jérôme LEMOINE, Maud GREGSON, Julie GIL, Romain CARRIERE, François VANDENESCH
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Patent number: 12181415Abstract: A method for identifying a microorganism to be identified, which includes the following steps: obtaining an Excitation-Emission EEM of the microorganism to be identified, analysing the main components of the EEM matrix using at least one reference EEMr matrix, projecting the result of the analysis onto a plane defined by two main components, and identifying the microorganism to be identified.Type: GrantFiled: November 27, 2020Date of Patent: December 31, 2024Assignees: UNIVERSITE DU MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS-, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS, UNIVERSITE D'ANGERSInventors: Jean-François Bardeau, Jean-Philippe Bouchara
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Patent number: 12178790Abstract: Aspidin BB derivatives, compositions containing them, and methods of making and using them.Type: GrantFiled: August 5, 2021Date of Patent: December 31, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Jonathan Sorres, Véronique Eparvier
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Publication number: 20240426624Abstract: The method (P1) for detecting a boundary (L1, L2, L3) of a traffic lane (VC1, VC2) for a motor vehicle (1) involves: (E1) detecting the boundary by a vehicle environment detection means (3), the boundary being defined by a function, in particular a polynomial function, (E4) determining a plurality of first vectors (MXi) characterizing the boundary on the basis of map data and on the basis of data on the current position and orientation of the vehicle, (E6) determining a plurality of second vectors (Fj) characterizing the boundary, each second vector being determined by an orthogonal projection of a first vector onto said function, and (E8) calculating Mahalanobis distances between each first vector and each second vector.Type: ApplicationFiled: October 10, 2022Publication date: December 26, 2024Applicants: AMPERE S.A.S., CNRS, UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE (UTC)Inventors: Federico Camarda, Véronique Cherfaoui, Franck Davoine, Bruno Durand
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Publication number: 20240424297Abstract: A method for determining a profile of stimulation charge rate for at least one muscle or group of muscles of a subject using the ergometer equipped with a FES system, the profile of stimulation charge rate being specific to the ergometer user. Also, a method for stimulation intervals for at least one muscle or group of muscles of a subject using the ergometer equipped with a FES system. Further, an ergometer, preferably a cyclic ergometer such as an electric stimulation stationary bike, including a FES controller with instructions to operate the method.Type: ApplicationFiled: September 16, 2022Publication date: December 26, 2024Applicants: KURAGE, ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: Lana POPOVIC MANESKI, Amine METANI
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Patent number: 12169286Abstract: A device for creating a patterned field on a diopter includes: an objective lens within whose image focal plane the surface of the diopter lies; a light injection element emitting a collimated light beam; and an optical assembly between the element and the objective lens by which the object plane of the objective lens is optically conjugate with the image plane of the element. The assembly is configured so a collimated light beam from the element is emitted towards the objective lens to be reflected towards the surface of the diopter with an angle of incidence?the critical angle of the diopter, an optical device for forming patterns is in the object plane of the element, so the pattern formed by the optical device for forming patterns in transmitted light on the light beam in the object plane of the element is on the surface of the diopter.Type: GrantFiled: May 13, 2020Date of Patent: December 17, 2024Assignees: UNIVERSITÉ GRENOBLE ALPES, CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE)Inventors: Alexei Grichine, Olivier Destaing
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Patent number: 12169761Abstract: Control system (1) for a state of a quantum harmonic oscillator, comprising: —a harmonic oscillator (3) in a Schrödinger's cat type state, —a stabilisation device (10) with a predetermined parity of a number of bosons of the state, which device is configured to use first and second frequency combs each comprising at least as many rays as a mean number of bosons in the state, and —a multiphonic dissipation device (20) which is suitable for removing at least one pair of bosons simultaneously from the oscillator, the dissipation device being activated only between two successive time peaks of the frequency combs over a time period greater than the inverse of the product of the mean number and the inverse of the characteristic time of the multiphonic dissipation, a time period separating two activation periods being less than a characteristic loss time of a boson.Type: GrantFiled: December 16, 2021Date of Patent: December 17, 2024Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE DE LYONInventors: Théau Peronnin, Benjamin Huard, Sébastien Jezouin, Antoine Marquet
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Publication number: 20240409869Abstract: A fluidic system for producing extracellular vesicles from producer cells, including at least one container, a liquid medium contained by the container and producer cells, characterised in that it also includes microcarriers suspended in the liquid medium, the majority of producer cells being adherent to the surface of the microcarriers, and a liquid medium agitator, the agitator and the dimensions of the container being adapted to control a turbulent flow of the liquid medium in the container.Type: ApplicationFiled: August 19, 2024Publication date: December 12, 2024Applicants: UNIVERSITE DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), GENETHONInventors: Florence GAZEAU, Amanda Karine Andriola SILVA, Otto-Wilhelm MERTEN, Claire WILHELM, Max PIFFOUX
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Publication number: 20240409588Abstract: The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for altering a target nucleic acid.Type: ApplicationFiled: June 13, 2024Publication date: December 12, 2024Applicants: Institut National De La Sante Et De La Recherche Medicale (INSERM), Centre National De La Recherche Scientifique (CNRS), Ecole Normale Superieure De Lyon, Universite Claude Bernard Lyon 1Inventors: Théophile OHLMANN, Philippe MANGEOT, Emiliano RICCI
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Publication number: 20240391851Abstract: The present invention relates to a process for the non-oxidative conversion of saturated C1+ hydrocarbons into unsaturated C2+ hydrocarbons and hydrogen in the presence of an unsupported carbon-based catalyst having a carbon content of at least 90.0 wt % and a metal concentration which is less than 0.3 wt %; with wt % expressed based on the total weight of said carbon-based catalyst. The present invention also provides a process for producing a graphite derivative. Further provided are a graphite derivative, and uses thereof, and systems for carrying out the processes of the invention.Type: ApplicationFiled: October 26, 2022Publication date: November 28, 2024Applicants: TOTALENERGIES ONETECH, UNIVERSITÉ DE STRASBOURG-UNISTRA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRSInventors: Stijn VAN DAELE, Nikolai NESTERENKO, Jean-Pierre DATH, Miroslave KETTNER, Cuong PHAM-HUU, Jean-Mario NHUT, Zhenxin XU
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Publication number: 20240391887Abstract: The present invention concerns a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, wherein X, R1, R2, R3 are defined, a conjugate thereof and their uses as drug or research tools.Type: ApplicationFiled: August 24, 2022Publication date: November 28, 2024Applicants: Centre National de Recherche Scientifique (CNRS), Universite de Montpellier, Ecole Nationale Superieure de Chimie de Montpellier, MT ACTInventors: Krzysztof ROGOWSKI, Muriel AMBLARD-CAUSSIL, Siem VAN DER LAAN, Lubomir VEZENKOV, Guillaume MARCELLIN, Yoann LANNAY, Khaled HACHED
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Patent number: 12146150Abstract: Described herein are compositions and methods for treating Friedreich's Ataxia (FA) using adeno-associated virus (AAV) to deliver therapeutics agents.Type: GrantFiled: September 13, 2022Date of Patent: November 19, 2024Assignees: VOYAGER THERAPEUTICS, INC., INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE STRASBOURGInventors: Dinah Wen-Yee Sah, Martin Goulet, Holger Patzke, Yanqun Shu, Jinzhao Hou, Hélène Puccio
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Publication number: 20240377341Abstract: The invention relates to a method for non-destructively testing a part by means of transmission radiography, which method comprises the following steps of acquiring N projections (P(n)) of the part, generating calculated N images (P(n)) of the part, estimating, by successive iterations, the vector p from an initial vector p=pini and the vector c from an initial vector c=cini and/or the parameter vector a from an initial vector ?=?ini, by minimising the sum of the squared differences between the projections (P(n)) and the images (P(n)), processing the projections (P(n)) and/or the images (P(n)), identifying defects in the part by comparing the processed projections (P(n)) and the processed images (P(n)).Type: ApplicationFiled: September 8, 2022Publication date: November 14, 2024Applicants: SAFRAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE PARIS-SACLAYInventors: Cédric FRAGNAUD, Stéphane ROUX, Julian BETANCUR
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Patent number: 12142394Abstract: The invention relates to an electrically insulating composite material (1) comprising a polyepoxide matrix (2) of cycloaliphatic type or of diglycidyl ether type in a content of less than 40% by mass, from 20 to 75% by mass of one or several micrometric and/or mesometric filler(s) (3), and from 0.1 to 20% by mass of at least one ionic liquid (4), the masses being expressed relative to the total mass of the electrically insulating composite material (1). The invention also relates to a method for manufacturing such an electrically insulating composite material (1), as well as its use for an electrically insulating support (9) in a metal-enclosed substation (5).Type: GrantFiled: December 27, 2019Date of Patent: November 12, 2024Assignees: SUPERGRID INSTITUTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE JEAN MONNET SAINT ETIENNE SAINTInventors: Thibaut Lefort, Damien Bachellerie, Sébastien Pruvost, Jannick Duchet, Sébastien Livi
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Patent number: 12128640Abstract: The disclosure provides a process for treatment of an article (1) made of a polymer composition; comprising the steps of providing an article (1) with a surface, the article being made of a polymer composition comprising one or more polyolefins; providing one or more texturing solvents (3, 5, 7, 9) selected from one or more vegetable oils, one or more terpenes, one or more alkanes and any combination thereof; wherein the one or more texturing solvents (3, 5, 7, 9) are further selected to have a boiling point which is above the crystallisation temperature Tc of the one or more polyolefins and to be devoid of a halogenated atom and/or an aromatic group; contacting the surface of the article (1) with the one or more texturing solvents (3, 5, 7, 9); and recovering an article with a textured surface with water contact angle following ISO 19403-6:2017 that is increased by comparison to the initial water contact angle.Type: GrantFiled: October 24, 2022Date of Patent: October 29, 2024Assignees: TOTALENERGIES ONETECH, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Olivier Lhost, Guillaume Espy, Jannick Duchet-Rumeau, Jean-François Gerard, Sébastien Livi
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Patent number: 12122806Abstract: The present invention relates to new adenoviral coat protein based delivery vehicles. They are based on a modified penton base protomers that assemble into VLPs. Exposed areas of the penton base proteins can be modified to allow the VLP to specifically bind to any target and/or to comprise any desired peptide epitope. Additional cargo, for example drugs, proteins, or nucleic acids, can reversibly or irreversibly attached to the VLP via engineered fibre protein fragments.Type: GrantFiled: February 1, 2022Date of Patent: October 22, 2024Assignees: THE EUROPEAN MOLECULAR BIOLOGY LABORATORY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Imre Berger, Frédéric Garzoni, Pascal Fender
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Publication number: 20240342481Abstract: A current switcher including: a positive supply bus and a negative supply bus; a floating-output current amplifier configured to make flow, as an output, an intermediate current dependent on a flowing setpoint current implied as an input; at least one anodic reference dipole connected between the positive supply bus and the floating-output current amplifier; at least one cathodic reference dipole connected between the floating-output current amplifier and the negative supply bus; and at least two stimulation bridges, each stimulation bridge including an anodic current source and a cathodic current source each configured to copy the intermediate current.Type: ApplicationFiled: July 29, 2022Publication date: October 17, 2024Applicants: NEURINNOV, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, INRIA - INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE, UNIVERSITÉ DE MONTPELLIERInventors: David GUIRAUD, David ANDREU, Milan DEMARCQ, Guy CATHEBRAS, Sami AJRAM
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Patent number: 12120892Abstract: The application relates to organic-inorganic hybrid perovskites of formula (I): [(A)1?2.48p?b(B)3.48p+b](1+2p?y)/1+p)(Pb)1?p?m(M)m(X1)3?y?q(X2)q(I), and perovskite photovoltaic cells comprising the same.Type: GrantFiled: July 19, 2018Date of Patent: October 15, 2024Assignees: UNIVERSITÉ D'ANGERS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), CHIMIE PARISTECHInventors: Nicolas Mercier, Antonin Leblanc, Thierry Pauporté