Abstract: The disclosure relates to N-alkyl-D-glucamine based macroporous polymeric cryogels with three-dimensional structure and with interconnected pores, which are used for sequestering and/or removing toxic contaminants, such as toxic metalloids and/or toxic heavy metals, for example from water and/or soil and the method for the preparation of said -alkyl-D-glucamine based macroporous polymeric cryogels.

Abstract: A device for sensing a magnetic field, comprising a closed superconducting loop configured to collect a magnetic field to be sensed, hereinafter external magnetic field, the closed superconducting loop having a path width (wp) and being provided with a constriction having a width (wc) narrower than the path width, the constriction generating a non-uniform magnetic field, hereinafter internal magnetic field, in response to the external magnetic field, a vibrating mechanical oscillator coupled to, or formed by the constriction and responsive to the internal magnetic field, and a detector configured to detect deflection or vibration of the mechanical oscillator and providing a signal indicative of the deflection or vibration.

Abstract: A climate generator adapted to produce a flow of air at controlled temperature and at relative humidity values (tc, ic) is described, which includes a bubbler (100) which receives a flow of air to be conditioned (Ga), heat exchangers (120) associated with the bubbler (100) to adjust the temperature of the water volume (W) of the bubbler and/or to provide an amount of latent heat of evaporation to the aforesaid volume of water (W); and heaters (180) for heating the flow of air at the dew point (Gb) exiting from the bubbler (100) to the controlled temperature value of the flow of air, wherein the temperature of the volume of water (W) is established as a function of the controlled temperature and relative humidity values (tc, ic), so that the heating of the flow of air at the dew point (Gb) from the temperature of the water volume (W) to the controlled temperature value determines a decrease in the relative humidity (ic) of the flow of air to the controlled relative humidity value.

Abstract: Method of doping a semiconductor sample in a uniform and carbon-free way, wherein said sample has a surface, comprising the following steps: A. removing oxides from at least part of the said surface; B. dip coating said at least part of the surface of the sample in a dopant based carbon-free solution of at least one dopant based carbon free substance diluted in water, wherein said at least one dopant based carbon free substance has a molecule comprising at least one dopant atom, wherein the dip coating is achieved by heating said dopant based carbon-free solution at a dip coating temperature from 65% to 100% of the boiling temperature of said dopant based carbon-free solution, thereby a self-assembled mono-layer including dopant atoms is formed; C. annealing said sample, wherein the annealing is configured to cause said dopant atoms included in said self-assembled mono-layer to be diffused into the sample.

Abstract: It is described a process, starting from fishbones, for the production of a material having properties of physical type solar filter and photoprotective boosting agent, formed by particles of hydroxyapatite or hydroxyapatite substituted with metal ions, optionally mixed with calcium triphosphate and with metal oxides. Are also described the material obtained through the process and cosmetic or plant sunscreen compositions that comprise said material.

Abstract: A Fourier-transform hyperspectral imaging system may include an optical imaging system configured to produce an image of an object, and an adjustable birefringent common-path interferometer module comprising a movable birefringent element and configured to produce interfering replicas of an input radiation which are delayed from each other by a phase delay adjustable by the moving birefringent element. The interferometer module may be configured to produce collinear replicas for entering optical rays parallel to said optical axis. The hyperspectral imaging system further comprises a two-dimensional light detector configured to receive the replicas and provide digital images of the object depending on said adjustable phase delay. The system also includes an analysis device configured to perform a Fourier Transform of the digital images to obtain a hyperspectral representation of the object.

Abstract: A nanoparticle comprising a keratin polypeptide and at least one lipophilic active ingredient, wherein the at least one lipophilic active ingredient is non-covalently bound to the keratin polypeptide and can be e.g. a therapeutic or diagnostic agent, a nutraceutical, a cosmetic ingredients, a dye or a cosmeceutical, the keratin polypeptide being water-soluble; optionally, the nanoparticle further comprises at least one hydrophilic active ingredient non-covalently bound to the keratin polypeptide, which can be e.g. a therapeutic or diagnostic agent, a nutraceutical, a cosmetic ingredients, a dye or a cosmeceutical.

Abstract: An implantable medical device obtained by means of two-photon laser polymerisation of a resin to form a three-dimensional matrix, wherein: said three-dimensional matrix comprises a number of levels distributed in height; and said three-dimensional matrix comprises reference means designed to uniquely identify the height of each level from a pre-set reference, by means of a multi-photon fluorescence-excitation microscope; said implantable medical device being characterised in that said reference means comprise a solid having a cross section that varies with height.

Abstract: A system and a method for measuring the focus state of an optical instrument are described. The system and the method provide for forming an image of the exit pupil of the objective of the optical instrument. Where the image of the exit pupil is formed, one or more optical elements are placed, deviating at least part of the rays coming from the exit pupil, so that rays coming from different non-overlapping portions of the pupil follow separate optical paths. The rays coming from the two portions of the pupil are then focused, in order to obtain two bidimensional images. A computer determines the mutual distance between these two bidimensional images as a mutual rigid lateral displacement between the two and, based on this distance, determines the corresponding defocus of the optical instrument.

Abstract: The present invention relates to a process for preparing a composite, ultra-refractory, fibre-reinforced ceramic material obtained through the infiltration of carbon and/or silicon carbide fibres with a ceramic suspension comprising yttrium, lanthanum and/or scandium compounds, and the subsequent densification of the composite. The fibre-reinforced UHTC compounds obtained by the process can be used for making items intended for use in extreme temperature and pressure conditions.

Abstract: A multifunctional solid-state photovoltachromic device (1) comprising at least one n-type layer (8) and at least one p-type layer (11) arranged to create a PN or PIN junction, said n-type layer (8) and p-type layer (11) comprising materials arranged to act as mixed conductors, thus allowing both charge transport and ion conduction.

Abstract: The present invention relates to a process for the production of fiber-reinforced composite materials with an ultra-refractory, high tenacity, high ablation resistant matrix with self-healing properties, prepared from highly sinterable slurries. The composite material is produced using techniques of infiltration and drying at ambient pressure or under vacuum, and consolidated by sintering with or without the application of gas or mechanical pressure.

Abstract: A device is disclosed for detecting time-resolved optical data, the device comprising a sensor comprising a number of detection elements configured to detect a light signal in a single photon regime, a timing circuit connected to said number of detection elements though a common line, and a control module connected to the sensor, the control module being configured to selectively enable the detection elements of the sensor according to a set of enabling patterns. The timing circuit is configured to measure a time of arrival of an output signal from the detection elements on the common line, the output signal being indicative of the detection of a photon of the light signal by any of the enabled detection elements.

Abstract: The present invention relates to a membrane chromatography process for selectively separating and purifying phycobiliproteins starting from aqueous biomasses of cyanobacteria and algae that, in a short time and at reduced cost, allows to obtain phycobiliproteins with a high degree of purity for use in pharmaceutical, cosmetic, or food compositions or as reagents for research.

Abstract: A protease-resistant neurotrophic peptide is provided. A pharmaceutical composition including the protease-resistant neurotrophic peptide in a pharmaceutically acceptable carrier, in combination with optional adjuvants, stabilizers and/or preservatives, is also provided.

Abstract: The present invention refers to an antibody or an antigen binding fragment thereof against a tau-derived neurotoxic peptide for use in the treatment and/or prevention of Alzheimer's disease (AD) or a non-AD tauopathy, as well as pharmaceutical compositions comprising the same.

Abstract: A Fourier-transform hyperspectral imaging system may include an optical imaging system configured to produce an image of an object, and an adjustable birefringent common-path interferometer module comprising a movable birefringent element and configured to produce interfering replicas of an input radiation which are delayed from each other by a phase delay adjustable by the moving birefringent element. The interferometer module may be configured to produce collinear replicas for entering optical rays parallel to said optical axis. The hyperspectral imaging system further comprises a two-dimensional light detector configured to receive the replicas and provide digital images of the object depending on said adjustable phase delay. The system also includes an analysis device configured to perform a Fourier Transform of the digital images to obtain a hyperspectral representation of the object.

Abstract: The present invention relates to a supermatrix of synthetic niches comprising at least two matrices of niches wherein each matrix comprises n×m niches and wherein the distance (d) between a matrix and the other is greater than zero and wherein in each matrix every synthetic niche has one or more walls in common with the others synthetic niches of the matrix. A support for the culture of cells that includes at least one supermatrix and the use of said supermatrix or support for the in vitro culture of cells, in particular stem cells, or for the in vivo implant in a subject in order to promote tissue or organ regeneration through cell repopulation are also within the scope of the present invention.

Abstract: The mitotic kinases regulating the dynamics of centrosomes and the functions of the mitotic spindle are potential targets for the antitumour therapy. In the present invention some molecules with inhibitory activity on NEK6 have been identified. The present invention relates to such molecules and to the compositions including them for use as inhibitors of NEK6 in a method of treatment of tumours both in monotherapy and in combinations with other drugs.

Abstract: A superconducting logic element includes a superconducting tunnel junction including first and second superconductors. First and second insulating ferromagnets in contact with the first and second superconductors, respectively, generate by magnetic proximity effect a predetermined density of spin-split states in the first and second superconductors, respectively. A writing element applies a writing current to at least a superconductor and is in contact with one of the first or second insulating ferromagnets, so that the first and second insulating ferromagnets commute, by the magnetic field generated by the applied writing current, between a state with parallel magnetization to a state with antiparallel magnetization with respect to each other.