Patents Assigned to Consiglio Nazionale Delle Ricerche
  • Patent number: 9939829
    Abstract: Low-noise current source, configured to be supplied by at least one DC main supply (Vss) and to deliver an output current (IL), the source comprising one or more current generator modules (G1, G2, . . . GN) operating in parallel each one of which is configured to deliver a respective output current (Ii), whereby the output current (IL) of the source is equal to the sum of the output currents (Ii) of said one or more current generator modules (G1, G2, . . . GN), each current generator module (G1; G2; . . . GN) comprising a regulator component (Q1), configured to deliver the output current (Ii) of the current generator module (G1; G2; . . .
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: April 10, 2018
    Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, UNIVERSTÀ DEGLI STUDI DI FIRENZE
    Inventors: Saverio Bartalini, Alessio Montori, Marco De Pas, Mauro Giuntini, Paolo De Natale
  • Publication number: 20180093247
    Abstract: A photochemical reactor (1) having a hollow container body (10) having a side wall (11) made of a material arranged to contain an excited luminous plasma with electromagnetic fields and defining a closed excitation chamber (12) in which, in use, an excitable material (15) is present in such a way to obtain a discharge of the excited luminous plasma by microwave irradiation. The hollow container body (10) is provided with at least a hollow (20) that protrudes into the excitation chamber (12) and at least a microwave radiation source positioned, in use, in the hollow (20), and arranged to emit radiations in such a way to excite the excitable material (15) producing a luminous plasma.
    Type: Application
    Filed: March 17, 2016
    Publication date: April 5, 2018
    Applicant: CNR - CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Iginio LONGO, Carlo FERRARI
  • Patent number: 9927602
    Abstract: A video-confocal microscopy method for creating an image of an optical section (?) of a sample (99), provides, in one aspect of the invention, illuminating the sample (99) with illumination beams (19) concentrated on spots (x,y) arranged in an illumination pattern (18) in an illumination plane (?0) at the optical section (?); translationally parallel moving the pattern (18) of spots (x,y) to a plurality of positions in the illumination plane; it also provides for each position (u,v) of the illumination pattern (18), receiving light (21) returned by the sample (99) by reflection and/or transmission and/or phosphorescence, and detecting raw images (52), each having a light intensity distribution Iu,v(x,y) on said image detector.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: March 27, 2018
    Assignee: CNR CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventor: Pier Alberto Benedetti
  • Patent number: 9873843
    Abstract: A process for the conversion of a feedstock containing one or more fatty acid triglycerides to a mixture containing one or more fatty acid alkyl esters and t-alkyl glycerols, including reacting the feedstock with a compound of formula (I): R—O—RI??(I) wherein: RI is an alkyl, alkenyl or alkynyl having 1-18 carbon atoms; R is H or a tertiary alkyl group, wherein the reaction takes place in the presence of an acid transesterification catalyst by irradiation with microwaves and/or ultrasound and/or radio waves.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: January 23, 2018
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Giovanni Nicolosi, Carmelo Drago, Leonarda Francesca Liotta, Valeria La Parola, Maria Luisa Testa
  • Publication number: 20180003499
    Abstract: A system for monitoring a building structure is described. The system comprises a laser source which emits an infrared radiation and an interferometric arrangement which divides the radiation into an object beam and a reference beam. The object beam irradiates the building structure and is scattered by it, while the reference beam interferes with the scattered object beam so as to create a hologram of the building. The system also comprises a sensor which detects a sequence of holograms and a processing unit which reconstructs the evolution in time of deformations or displacements of the building by numerically processing the sequence of holograms. The system—being based on digital holography—offers various advantages compared to known monitoring techniques, for example techniques which make use of seismometers (possibility of remote monitoring, substantial space-time continuity of the monitoring, capacity for detecting a wider range of deformations and displacements).
    Type: Application
    Filed: January 28, 2016
    Publication date: January 4, 2018
    Applicants: CONSIGLIO NAZIONALE DELLE RICERCHE - CNR, UNIVERSITA DEGLI STUDI Dl FIRENZE
    Inventors: Massimiliano LOCATELLI, Pasquale POGGI, Eugenio PUGLIESE, Giorgio LACANNA
  • Patent number: 9856857
    Abstract: A method and system for converting mechanical energy from a generator operated by a turbine into electric energy to be input into an electric network, comprising the following: (A) supplying a power electronic converter connectable to input of the generator and to output of the electric network; (B) supplying an electrical power outputting the generator to the power electronic converter; (C) adapting the electrical power using the power electronic converter to input the electrical power to the electric network by the following substeps: (C1) calculating rotation speed of the turbine; (C2) calculating wind speed moving the turbine; (C3) calculating reference rotation speed, corresponding to the maximum point of power input to the electric network, using a Maximum Power Point Tracking algorithm; the method comprising substep (C1) implemented by an algorithm carrying out a virtual encoder, and substep (C2) implemented by training a neural network implementing a virtual anemometer.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: January 2, 2018
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Gianpaolo Vitale, Marcello Pucci, Massimiliano Luna
  • Publication number: 20170371211
    Abstract: A method is disclosed for realizing a liquid crystal tri-dimensional aligned structure, including: providing a first substrate having a first surface; forming a liquid crystal layer in contact to said first surface, said liquid crystal layer including a polymerizable liquid crystal compound; realizing a first aligning formation within said liquid crystal layer by irradiating a first portion of said liquid crystal layer with electromagnetic or electron beam radiation according to a given first pattern, so that said first portion of liquid crystal compound becomes polymerized and said first aligning formation is made of said polymerized liquid crystal compound according to said given first pattern, said first aligning structure defining a first aligning axis; locally orienting optical axes of molecules of said liquid crystal layer along said first aligning axis.
    Type: Application
    Filed: December 23, 2014
    Publication date: December 28, 2017
    Applicants: Consiglio Nazionale delle Ricerche - CNR, Laboratorio Europeo di Spettroscopie Non Lineari (LENS)
    Inventors: Hao ZENG, Piotr Jan WASYLCZYK, Diederik Sybolt WIERSMA, Camilla PARMEGGIANI, Chih-Hua HO
  • Publication number: 20170315573
    Abstract: Low-noise current source, configured to be supplied by at least one DC main supply (Vss) and to deliver an output current (IL), the source comprising one or more current generator modules (G1, G2, . . . GN) operating in parallel each one of which is configured to deliver a respective output current (Ii), whereby the output current (IL) of the source is equal to the sum of the output currents (Ii) of said one or more current generator modules (G1, G2, . . . GN), each current generator module (G1; G2; . . . GN) comprising a regulator component (Q1), configured to deliver the output current (Ii) of the current generator module (G1; G2; . . .
    Type: Application
    Filed: October 29, 2015
    Publication date: November 2, 2017
    Applicants: CONSIGLIO NAZIONALE DELLE RICERCHE, UNIVERSITÀ DEGLI STUDI DI FIRENZE
    Inventors: Saverio BARTALINI, Alessio MONTORI, Marco DE PAS, Mauro GIUNTINI, Paolo DE NATALE
  • Publication number: 20170246306
    Abstract: The present invention relates to a derivative of carnosine (?-alanyl-L-histidine) having formula (1), obtained by the functionalization of hyaluronic acid with carnosine.
    Type: Application
    Filed: July 30, 2015
    Publication date: August 31, 2017
    Applicants: CONSIGLIO NAZIONALE DELLE RICERCHE, FIDIA FARMACEUTICI S.P.A.
    Inventors: Sebastiano SCIUTO, Valentina GRECO, Enrico RIZZARELLI, Francesco BELLIA, Valeria LANZA, Susanna VACCARO, Luciano MESSINA
  • Patent number: 9730458
    Abstract: The present invention relates to the use of an enzymatic method for treating flour, semolina and protein extracts derived from cereals known to stimulate a pathological immune response in patients affected by Celiac Disease (CD). Said treatment drastically reduces or completely eliminates the toxicity of gluten or similar products derived from other cereals. The method uses the catalytic activity of microbial transglutaminase and, in particular, its ability to bind proteins in cereal flour or semolina to an alkylated (C1-C4) derivative of lysine. After the treatment said proteins extracted from flour show a substantially lowered immuno-stimulatory activity in celiac patients T lymphocytes.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: August 15, 2017
    Assignee: Consiglio Nazionale Delle Ricerche
    Inventors: Mauro Rossi, Carmela Gianfrani, Rosa Anna Siciliano
  • Patent number: 9730852
    Abstract: A device (7) for the rehabilitation of the movements of the foot (1) includes a supporting base (8) and a mobile platform (9) with a supporting surface (10) for resting the sole of the foot (1), wherein the mobile platform (9) is secured to the supporting base (8) by a pure rotation movement mechanism (12) with three degrees of freedom of rotary movement independent the one from the other and placed in parallel which allow rotations of the mobile platform around three axes (13, 14, 15) which intersect one another in a single rotation center (P). The supporting surface (10) is turned towards the rotation center (P) and is distant from the rotation center (P) in such a way that the rotation center (P) is positioned in correspondence to the ankle (2) of the foot (1).
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: August 15, 2017
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Matteo Malosio, Simone Pio Negri, Nicola Pedrocchi, Marco Caimmi, Federico Vicentini, Lorenzo Tosatti Molinari
  • Patent number: 9726833
    Abstract: An optical interconnection assembly for the mutual connection of a plurality of signal switching circuit boards that may be coupled to a common planar support, backplane, includes a planar support frame, adapted to receive an ordered arrangement of connectors, which includes a series of first connectors arranged to face corresponding signal transmission ports of said boards, and a series of second connectors arranged to face corresponding signal reception ports of the boards. The support frame is adapted to guide the deployment of an interconnection circuit between corresponding pairs of first and second connectors.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: August 8, 2017
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Vito Basile, Irene Fassi, Gianluca Guadagno
  • Publication number: 20170209491
    Abstract: Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand, and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other, which are mixed at room temperature. The process is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.
    Type: Application
    Filed: July 21, 2015
    Publication date: July 27, 2017
    Applicants: Consejo Superior De Investigaciones Científicas (C SIC), Consiglio Nazionale Delle Ricerche
    Inventors: Jose Manuel Delgado Lopez, Jaime Gomez Morales, Raquel Fernandez Penas, Michele Iafisco, Anna Tampieri, Silvia Panseri
  • Publication number: 20170130272
    Abstract: The invention relates to an in vitro or in vivo method for diagnosing Paget's disease or bone tumors associated therewith or for determining the predisposition of a subject affected by Paget's disease of bone to develop a bone tumor, the method being based on the detection of a mutation in the nucleotide sequence of the ZNF687 gene or in the amino acid sequence of the protein encoded by the mutated ZNF687 gene. The invention also refers to isolated nucleic acids comprising the mutated nucleotide sequence of the ZNF687 gene or a portion thereof and the encoded amino acid sequences.
    Type: Application
    Filed: May 21, 2015
    Publication date: May 11, 2017
    Applicant: Consiglio Nazionale Delle Ricerche
    Inventor: Fernando Gianfrancesco
  • Patent number: 9630954
    Abstract: The T cells specific to human collagen type II, one of the possible autoantigens, have a crucial role in the development of rheumatoid arthritis in the context of HLA-DR4. The protein-protein interactions between the T cell receptor (TCR) and the type II collagen linked to the allele MHC of class II HLA-DR4 may thus represent the target for the development of new drugs against rheumatoid arthritis. Using computational virtual screening techniques, families of pharmacologically active molecules have been identified that interfere with the TCR/collagen ll-MHCII interaction. The compounds identified here open up new possibilities in the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: April 25, 2017
    Assignees: Consiglio Nazionale delle Ricerche, Università Cattolica del Sacro Cuore
    Inventors: Maria Cristina De Rosa, Francesco Ria, Bruno Giardina, Gianfranco Ferraccioli, Davide Pirolli, Chiara Nicolo′
  • Patent number: 9612427
    Abstract: A microscopy optoelectronic device for reconstructing a three-dimensional model of a sample, which can be connected to any PC in order to obtain three-dimensional surface micro-reliefs, includes a portable device body, having a casing and a frame supporting: a digital optical sensor; an optical group, coupled to the sensor including an objective lens directed towards a distal end of the device body, faceable towards the sample; a motor that translates the optical group and sensor with respect to said frame; a connector to connect the device body to an energy source and to a device that controls the position of the optical group and to transmit the digitalized images; and a light source that provides diffused lighting at the objective lens arranged to surround a front region with respect to the objective lens and also includes a luminescent and diffusing surface having a tubular portion coaxial to the optical group.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: April 4, 2017
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Salvatore Siano, Andrea Azelio Mencaglia, Ilaria Cacciari
  • Patent number: 9613792
    Abstract: An elongated light source envelope is disclosed. The elongated light source comprises an inner wall and an outer wall formed around a longitudinal axis. The inner wall and the outer wall may be connected at a first axial end by a first side wall and a second axial end by a second side wall. The inner wall, outer wall, the first side wall, and the second side wall define an enclosed space internal to the envelope. The light source envelope further comprises one or more walls formed between the inner wall and the outer wall to further form at least a first enclosed region and a second enclosed region within the enclosed space. The first enclosed region may be configured to emit a different spectrum of ultraviolet radiation from the second enclosed region in response to excitation of the first enclosed region and the second enclosed region by microwave radiation.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 4, 2017
    Assignees: Heraeus Noblelight America LLC, Consiglio Nazionale Delle Ricerche
    Inventors: Andrew David Paul Harbourne, Pradyumna Kumar Swain, Iginio Longo, Carlo Ferrari
  • Patent number: 9575029
    Abstract: A transistor includes at least one conductive layer, at least one gate dielectric layer and at least one semiconducting film deposited on top of a receptor molecule layer previously deposited or covalently linked to the surface of the gate dielectric. The layer of biological material includes single or double layers of phospholipids, layers made of proteins such as receptors, antibodies, ionic channels and enzymes, single or double layers of phospholipids with inclusion or anchoring of proteins such as: receptors, antibodies, ionic channels and enzymes, layers made of oligonucleotide (DNA, RNA, PNA) probes, layers made of cells or viruses, layers made of synthetic receptors for example molecules or macromolecules similar to biological receptors for properties, reactivity or steric aspects.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: February 21, 2017
    Assignees: UNIVERSITA DEGLI STUDI DI BARI, CONSIGLIO NAZIONALE DELLE RICERCHE ISTITUTO PROCESSI CHIMICO FISICI-IPCF, SEDE DI BARI
    Inventors: Luisa Torsi, Gerardo Palazzo, Nicola Cioffi, Maria Daniela Angione, Maria Magliulo, Serafina Cotrone, Gaetano Scamarcio, Luigia Sabbatini, Antonia Mallardi
  • Patent number: 9561355
    Abstract: There is described a method for making an array of micro-needles, comprising the steps of: depositing a plurality of drops of a liquid substance comprising a polymer on a surface of a starting substrate; positioning a pyroelectric substrate at a certain distance from the starting substrate in such a way that the drops deposited are positioned between said surface of the starting substrate and a surface of the pyroelectric substrate; varying the temperature of the pyroelectric substrate or a part thereof to induce on said surface of the pyroelectric substrate a charge density such that starting from the drops deposited, under the effect of an electrodynamic force, respective cones are formed having a tip facing towards the pyroelectric substrate; determining a consolidation of the cones, to form said micro-needles, preventing the tip of said cones from contacting said surfaces of the pyroelectric substrate.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: February 7, 2017
    Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
    Inventors: Pietro Ferraro, Sara Coppola, Andrea Finizio, Simonetta Grilli, Veronica Vespini, Paolo Antonio Netti, Raffaele Vecchione, Eliana Esposito
  • Patent number: 9505086
    Abstract: In a method for detecting flaws in continuous laser welding processes, including a sensor measures plasma emission spectrum in a range of wavelengths between ?max and ?min in N channels, each measuring radiation strength emitted in the band centered at wavelength ?i (1?i?N) and width ??i. Deviation detection is based upon calculating intensity relationships of signals measured at specific wavelengths and in comparison with pre-determined threshold values. A calibration phase ensures a series of K weldings is performed, under optimized conditions, for each a number J of spectra OJ,K, is acquired, each one corresponding to a vector of N intensity values at wavelengths ?i, 1?i?N, and a series of weldings K? is then performed, (K??K), a single welding parameter A is altered by a known quantity, for each welding being acquired a sequence of J? spectra AJ?,K?, (J??J), which are stored.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: November 29, 2016
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Guido Toci, Roberto Pini