Patents Assigned to Corixa Corporation
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20080219988
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 11, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Jiangchun Xu, Davin C. Dillon, Jennifer L. Mitcham, Susan L. Harlocker, Yuqiu Jiang, Robert A. Henderson, Michael D. Kalos, Gary R. Fanger, Marc W. Retter, John A. Stolk, Craig H. Day, Thomas S. Vedvick
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080219982
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 11, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080219989
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 11, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080219991
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 11, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • COMPOUNDS AND METHODS FOR TREATMENT AND DIAGNOSIS OF CHLAMYDIAL INFECTION
    Publication number: 20080213264
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 4, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • HER-2/NEU FUSION PROTEINS
    Publication number: 20080213295
    Abstract: The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and pharmaceutical compositions (e.g., vaccines) comprising the HER-2/neu fusion proteins and/or nucleic acid molecules encoding the HER-2/neu fusion proteins. The present invention is also directed to methods of treating or preventing cancer by eliciting or enhancing an immune response to the HER-2/neu protein, including for uses in the treatment of malignancies associated with the HER-2/neu oncogene.
    Type: Application
    Filed: April 9, 2008
    Publication date: September 4, 2008
    Applicants: CORIXA CORPORATION, SMITHKLINE BEECHAM BIOLOGICALS S.A.
    Inventors: Martin A. Cheever, Dirk Gheysen
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080207486
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 31, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080207511
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080206234
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080206249
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080206250
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080207547
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080207548
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 31, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080206244
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080206245
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 28, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Gary R. Fanger, Shannon Kathleen Hirst, Davin C. Dillon, Teresa M. Foy, Raymond L. Houghton, David H. Persing, Michael D. Kalos
  • Compounds and methods for immunotherapy and diagnosis of tuberculosis
    Publication number: 20080199405
    Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
    Type: Application
    Filed: May 7, 2007
    Publication date: August 21, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Steven G. Reed, Yasir A.W. Skeiky, Davin C. Dillon, Antonio Campos-Neto, Raymond Houghton, Thomas S. Vedvick, Daniel R. Twardzik, Michael J. Lodes, Ronald C. Hendrickson
  • COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER
    Publication number: 20080200386
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 21, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • COMPOUNDS AND METHODS FOR TREATMENT AND DIAGNOSIS OF CHLAMYDIAL INFECTION
    Publication number: 20080199456
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 21, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Jeff Guderian, Yasir A.W. Skeiky, Jean-Francois L. Maisonneuve
  • COMPOUNDS AND METHODS FOR TREATMENT AND DIAGNOSIS OF CHLAMYDIAL INFECTION
    Publication number: 20080181918
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 31, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • COMPOUNDS AND METHODS FOR DIAGNOSIS AND IMMUNOTHERAPY OF TUBERCULOSIS
    Publication number: 20080176798
    Abstract: Compounds and methods for diagnosing tuberculosis or for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more Mycobacterium proteins and DNA molecules encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Mycobacterium infection in patients and biological samples. Antibodies directed against such polypeptides are also provided. In addition, such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against Mycobacterium infection.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 24, 2008
    Applicant: Corixa Corporation
    Inventors: Antonio Campos-Neto, Yasir Skeiky, Pamela Ovendale, Shyian Jen, Michael Lodes