Abstract: The invention describes a method to modulate melanosome maturation process in melanocytes. Further, it describes a method to reversibly alter the process of pigmentation in the human epidermal skin. The method targets melanosome maturation and its transfer to keratinocytes, which are key processes involved in the pigmentation for its potential use in predictable and controlled regulation of pigmentation in human skin.

Abstract: The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof. Wherein, R can be both linear and branched alkyl, aryl, substituted aryl and alkoxy alkyl. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.

Abstract: Development of an alternative process to conventional toxic chromic acid anodization (CAA) with equivalent corrosion resistance is a challenging task. The present invention provides a chromate free process for the manufacture of corrosion resistant sealed anodized coating for long term corrosion resistance of aerospace grade aluminum alloy. This method includes the steps of cleaning, chemical etching, anodizing in Tartaric-Sulphuric acid electrolyte followed by dipping the specimen in the sealing bath containing at least two water soluble either Mn and Mo or Mn and V oxyanions as corrosion inhibitors and a sufficient amount of alkali metal ion based nitrates at a temperature range between 60 and 80° C. for about 20 to 40 minutes at a pH range of 7 to 9. The sealed anodic coatings developed from this invention showed improved corrosion resistance in neutral 5% NaCl fog environment for greater than 2000 h of exposure.

Abstract: The present invention provides thermoelectric composite materials that comprise a physical mixture of semiconducting polymers and carbon nanotube structures. The present invention further provides a process to improve the thermoelectric power factor of the composite by doping with inorganic salts.

Abstract: The present invention discloses a novel mesoporous gold deposited oxidation catalyst of formula: XAu-M0.1Ce0.85Zr0.05O2 wherein X=0.01-10%, M is selected from Cu, Co or Mn and process for the preparation thereof by photodeposition method.

Abstract: A method for optimally producing a holographic image using a Holographic Optical Element (HOE) and the HOE meant for controlling directions and divergences of light beams to impart system compactness. The system uses concave and convex lenses and other beam expanding, splitting, modulating and combining optics for realization of compactness and high throughput. The thin laser beam is split using a holographic optical element and a conventional beam splitter. A neutral density filter adjusts the intensity of a reference beam to match the intensity of an object beam so that high quality digital holograms can be recorded. Effects of vibrations are minimized by the compact optical design, by anti-vibration mounts, by mounting all the opto-mechanical components on a single rigid platform and by enclosing the system. An electro-optical sensor array records holograms digitally and an algorithm numerically reconstructs and further quantifies the results using a personal computer/laptop/tablet etc.

Abstract: An apparatus for Vapour Liquid Equilibrium (VLE) data measurement of a mixture to establish a quick equilibrium and to avoid flashing is disclosed herein. With the known apparatus, the underlining problems are heat loss or improper mixing, flashing inside the apparatus High boiling point difference, and prolong time to establish equilibrium conditions. In order to overcome stated problems, the apparatus is provided with a vapour-liquid mixer (K) for proper mixing of equilibrium liquid from the equilibrium chamber and vapor condensate from the condenser (L) before recycling back to the boiling chamber (F) to avoid any temperature and composition gradient and for fast attainment of equilibrium. Additionally, a cooling jacket (P) is provided to a mixing chamber (K) and a connecting tube between an equilibrium chamber and the mixing chamber (K) to avoid flashing for the accurate measurement of VLE data.

Abstract: The present invention discloses a process for nitration of benzene. More particularly, the present invention discloses an efficient, environmental friendly process for the nitration of benzene using a modified solid acid catalyst.

Abstract: A multimodal micromixer obstacle for intensification of mixing and performing the reaction in a continuous manner is disclosed herein. The micromixer 100 comprises of plurality of inlets, an outlet and a plurality of channels. The end channels—of the channels, have plurality—of converging sections having width, to depth ratio ranging 1:1 to 20:1. The intermediate channels have at least, one obstacle having non-circular shape. Each converging section is incomplete ellipse, prolate or oblate shaped having, angle of curvature in the range of 90 to 270°. Axes of the inlets are coplanar and perpendicular to the channels. All the components of the micromixer are coplanar.

Abstract: Oil soluble organic-inorganic fused slurry phase hydroprocessing catalysts for heavy oils and residues are prepared at supercritical conditions. The hydrodemetallization, hydrodesulfurization, asphaltene conversion and hydrocracking activities of a residue having high percentage of metals, sulfur and asphaltene have been tested in an autoclave batch reactor. The different organic compounds are used to modify the solid fused material (catalyst). The effect of the concentration of modifier on the hydroprocessing and hydrocracking reactions has also been investigated.

Abstract: The present invention provides a method for the production of whey proteins in a single step process using combination of chromatography and membrane filtration technique, comprising treating cotton cloth with a mixture of chlorosulphonic acid and chloroform and then subsequently treating it with chloroform, dilute NaOH, glycine and water to recover modified cotton cloth as the product, thereafter fixing product in a membrane filtration device equipped with modified flow pattern and then equilibrating it with equilibration buffer, followed by loading of whey for adsorption of protein on the product and washing of the product with equilibration buffer, thereafter elution of adsorbed proteins with elution buffer, and then regeneration of the product by treating it with dilute HCl and water to reuse the product.

Abstract: The present invention relates to a self assembled catalyst. More particularly, the present invention relates to a self-assembled catalyst of formula (I) comprising supramolecular phosphine and carboxylate ligands, process for preparation thereof and use of said catalyst of formula (I) in olefin polymerization.

Abstract: A process for in vitro induction of flowering/in vitro proliferation of floral primordia in saffron crocus (Crocus sativus L.) produces whole flowers with real stigmas. The process produces saffron through a process of in vitro flowering to obtain season independent, continuous flowering of saffron.

Abstract: The present invention disclosed a novel (4,8-bis(5-(trimethylstannyl)thiophen-2-yl)benzo[1,2-b:4,5-b?]dithiophene-2,6-diyl)bis(trimethylstannane) compound, its preparation and use for the synthesis of polymers, which is used to build devices for capacitor and solar applications. The present invention further discloses to an improved process for the synthesis of DTBDT having improved yields.

Abstract: A process of depositing zirconium oxide (ZrO2) layers possessing dual properties of anti-reflection and passivation of silicon surfaces, including passivation of n-type and p-type silicon substrates. To grow a ZrO2 anti-reflection passivation layer, a precursor layer of zirconium oxide is spun on a silicon surface then dried, pyrolyzed and fired at suitable contact firing conditions, avoiding additional deposition. Thermal annealing in a hydrogen environment improves passivation quality of ZrO2 layer to a level 3-4 times higher than that of fired films alone. ZrO2 dielectric passivation layers exhibit improved passivation quality after illumination due to photo-enhanced passivation and higher passivation quality at higher thermal budget suitable for screen printed metal contact firing, unlike standard PECVD deposited passivation layers. The method is adaptable for fabrication of silicon solar cells and other structures utilizing passivated layers.

Abstract: The assimilated C and N largely influence plant growth and crop yields. Previous attempts to alter the carbon and nitrogen status of the plants attempted with one or two genes The present invention involves simultaneous co-overexpression of three genes wherein one gene (PEPCase) efficiently capture CO2 whereas the other two encode for enzymes (Asp AT and GS) involved in nitrogen assimilation. The combined effect is the enhancement of carbon and nitrogen status of the plant and the productivity.

Abstract: The present invention disclosed novel epoxy novolac composite comprising environmentally friendly toughening agents based on bio-derived chemicals namely, Difunctional glycidyl ether epoxy resin (Cardolite NC-514) and Polyglycidyl ether of an alkenyl phenol formaldehyde novolac resin (Cardolite NC-547) used for the toughening of epoxy novolac resin namely Poly[(phenyl glycidyl ether)-co-formaldehyde] [PPGEF].

Abstract: The current invention relates to development of new formulation containing gold nanoparticles (AuNPs) with bi-functional recombinant fusion proteins TRAF(C) for the delivery of anticancer drugs and nucleic acids to HER2+ cancers. Using the combinatorial approach, we designed gold nanoparticle-based targeted drug delivery system (TDDS) or (Au-TR-DX-si) by combining AuNPs with bi-functional recombinant fusion protein TRAF(C) (TR), doxorubicin (DX) and siRNA (si). The recombinant protein based gold nanoparticles formulations are stable and homogenous as revealed by several physicochemical studies. In addition, the engineered fusion protein TRAF (C) has the ability to target selectively to HER2+ receptors overexpressed in ovarian cancer cells (SK-OV-3).

Abstract: The present invention provides the polynucleotide encoding enzyme involved in lactone synthesis and a process for synthesis of lactones using said polynucleotides. The invention also provides recombinant plasmid expression vector comprising said polynucleotide sequence. The recombinant protein encoded by said polynucleotides leads to synthesis of lactones having flavour peculiar to Alphonso mangoes.

Abstract: The present invention provides a method for the preparation of multi-nutrient potassic fertilizer, by recovering potassium from sugarcane molasses based alcohol distillery effluent (commonly known as ‘spent wash’). The process involves pre-treatment of spent wash to clarify the aqueous phase and utilization of the treated spent wash in production of potassic fertilizer. The present invention enables utilisation of spent wash for recovery of value-added product (viz., potash fertiliser of >99% purity) and improves ease of ‘Zero Liquid Discharge’ compliance by subjecting the relatively benign process effluent to industrially practiced techniques for water recovery and salt reclamation.