Abstract: The present invention generally relates to a method of peptides' or polypeptides' modification by glycosylation. In particular, the invention relates to one pot synthesis of disaccharide glycan on to the acceptor substrate and thereby generating O- and/or S-glycosylated neo-glycopeptides including antimicrobial peptides by using multifunctional recombinant nucleotide dependent glycosyltransferase.
Type:
Grant
Filed:
March 30, 2017
Date of Patent:
November 1, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to an enzymatic process for preparation of optically pure enantiomers of homopropargylic alcohol compounds of formula I, which are useful intermediates for the synthesis of Halichondrin B and analogs. wherein, P is H or an alcohol protecting group, n is an integer ranging from 0-12.
Type:
Application
Filed:
June 17, 2020
Publication date:
October 20, 2022
Applicant:
Council of Scientific and Industrial Research
Abstract: A method and system for harvesting molecular structures from non-editable documents is disclosed herein. A non-editable storage document is fed by a feeder which is received by a receiver. The molecular and non-molecular data contained in the non-editable storage document is recognized. The three-dimensional coordinates of the molecular data is separated using a pattern recognition. The molecular coordinates are encoded by a pattern sequence. A bond matrix data of the encoded data is generated. Subsequently the bond matrix data for accuracy is verified by comparing with a stored standardized data into a library.
Type:
Grant
Filed:
January 19, 2017
Date of Patent:
September 27, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention is related to a novel gastroretentive swellable oral dosage form for sustained or delayed release of bergenin, a active constituent of Bergenia ciliata extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract of bergenin-rich Bergenia ciliata with polymers has resulted in a sustained release of extract in the stomach over a period of 16-24 hrs. The said formulations are useful for the treatment of inflammatory diseases.
Type:
Grant
Filed:
September 11, 2018
Date of Patent:
September 20, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to a new protocol for “Process development for 5-hydroxymethylfurfural (5-HMF) synthesis from carbohydrates”. A convenient, atom-economic, highly selective and cost-effective process has been developed for the preparation of 5-HMF from cellulose, hemicellulose, starch, different sources of carbohydrates and further extended to glucose and fructose.
Type:
Grant
Filed:
February 14, 2019
Date of Patent:
September 13, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention disclosed a process to coat the surface of flexible polymeric implant with biocompatible polymer such that the coating does not crack when the implant is subjected to mechanical forces such as tension, torsion or bending while retaining the inherent properties of the coated polymer.
Type:
Grant
Filed:
March 23, 2018
Date of Patent:
September 13, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention provides a fluorescent polymer comprising a fluorophore perylene bisimide (PBI) and oligo (p-phenylene vinylene) (OPV) functionalized with carboxy and amine functionality groups and a polystyrene (PS) backbone for the detection of volatile organic compound, a process for the detection and a kit thereof.
Type:
Grant
Filed:
February 18, 2019
Date of Patent:
August 30, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention provides a process for the preparation of essential oil modified nanocellulose and applications thereof. The invention further provides a process wherein the essential oil is covalently bonded with the nanocellulose such that the essential oil does not leach out. The edible coatings comprising the developed essential oil modified nanocellulose thus exhibit a prolonged antimicrobial effect.
Type:
Grant
Filed:
May 2, 2019
Date of Patent:
August 30, 2022
Assignee:
Council of Scientific and Industrial Research
Abstract: The present application provides a process of fabrication of erbium and ytterbium-co-doped multielements silica glass based cladding-pumped fiber for use as a highly efficient high power optical amplifier.
Type:
Grant
Filed:
January 9, 2019
Date of Patent:
August 9, 2022
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Inventors:
Paul Mukul Chandra, Dhar Anirban, Das Shyamal, Pal Mrinmay, Bhadra Shyamal Kumar
Abstract: The current invention relates to a polymer-lipid nanocomplex for enhanced aqueous solubilisation and absorption of hydrophobic active compounds, a process for producing such a nanocomplex, and to methods of use of such a nanocomplex.
Type:
Application
Filed:
May 8, 2020
Publication date:
July 28, 2022
Applicant:
COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH
Inventors:
Tshepo Patric Nkuna, Michel Lonji Kalombo
Abstract: The present invention discloses a novel microbial process for decontaminating (per)chlorate and/or nitrate containing matrices. A heterotrophic mixed microbial culture expressing the functional genes responsible for (per) chlorate and nitrate reduction is the major component of the process. The present process can be a better substitute for existing processes for decontaminating perchlorate contaminated propellant wastewater, ion exchange resin/regenerate solutions, etc. The consortium consists or comprises of Halomonas sp. NIIST-PRB-02 (MTCC No. 5911), Bacillus sp. NIIST-PRB-03 (MTCC No. 5912) and Serratia marcescens strain NIIST5 (MTCC No. 5821).
Type:
Grant
Filed:
December 30, 2016
Date of Patent:
July 19, 2022
Assignee:
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Abstract: The invention provides methods for the measurement of ground water characteristics. The carbon dot tracer is injected in an injection bore well. Carbon dot tracer and ground water are thoroughly mixed in the injection bore well. The ground water mixed with carbon dot tracer is pumped from the injection bore well to an acquiring bore well connected with injection bore well with micro and major fracture; the water samples mixed with carbon dot tracer were collected at the acquiring bore well. The characteristics of the ground water were measured by measuring fluorescence. The invention further relates to a method for depicting the solute transportation in the soil.
Type:
Application
Filed:
January 11, 2021
Publication date:
July 14, 2022
Applicant:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: The present invention disclosed a squaraine dye of formula (I) and process for the preparation thereof. Further, the present invention disclosed to an electronic device comprising dye of formula (I).
Type:
Grant
Filed:
July 28, 2017
Date of Patent:
July 5, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to a process for the production and recovery of a bio-surfactant extract from Bacillus sp. MCC0156. Further, the present invention relates to a thermostable bio-surfactant extract consisting of 1-Pentanonacontene and 3-hydroxy-16-methylheptadecanoic acid with excellent emulsification and oil displacement activity for applications in agriculture and oil recovery.
Type:
Application
Filed:
February 4, 2020
Publication date:
June 23, 2022
Applicant:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: The present invention provides a new artemisinin-dipeptidyl vinyl based compound of Formula (I) or a pharmaceutically acceptable salt thereof and a process for the preparation thereof. The present invention further also provides a pharmaceutical composition comprising compounds of Formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or excipient to treat malaria.
Type:
Grant
Filed:
April 16, 2019
Date of Patent:
June 21, 2022
Assignees:
Council of Scientific and Industrial Research, International Centre for Genetic Engineering and Biotechnology (ICGEB)
Abstract: The present invention discloses a process for the preparation of metal sulphide quantum dots by using a very low cost sulphur precursor as a sulphur source. The metal sulphide quantum dots finds application in optical devices selected from photovoltaic cells, photodetectors and light-emission devices.
Type:
Grant
Filed:
October 27, 2017
Date of Patent:
June 7, 2022
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Inventors:
Bhagavatula Lakshmi Vara Prasad, Abhjit Bera
Abstract: The present invention disclosed a shaped object comprising nano cellulose alone or a composition of nano cellulose for inclusion in a paper product and process for preparation thereof. The present invention further disclosed a paper product having the shaped objects incorporated therein. The shaped objects are used as a security feature for identifying and authenticating security documents.
Type:
Grant
Filed:
September 20, 2018
Date of Patent:
June 7, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to ?-spiroketal-?-lactones of formula (I) or a stereoisomer, ester, hydrate, solvate or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier, diluent or excipient and a process for preparation thereof. The present invention further provides a pharmaceutical composition comprising ?-spiroketal-?-lactones of formula (I) or a salt thereof.
Type:
Grant
Filed:
April 27, 2018
Date of Patent:
May 24, 2022
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention provides a polynucleotide having the nucleotide sequence as set forth in SEQ ID NO: 1 encoding 9-lipoxygenase. The present invention also provides recombinant plasmid expression vector comprising said polynucleotide. The recombinant protein 9-lipoxygenase encoded by the polynucleotide leads to production of lactones in fruits such as mangoes.
Type:
Grant
Filed:
March 31, 2017
Date of Patent:
May 24, 2022
Assignee:
Council of Scientific & Industrial Research