Abstract: An anti-inflammatory drug compound, and a preparation method therefor and the use thereof. The structural formula of the compound is A-Y—B, wherein A is a group after dehydrogenation of an amine compound having JAK inhibitory activity, Y is a direct connection or —(CH2)-O— or, and B is a group formed by means of dehydroxylation of a carboxy-containing carboxylic acid compound B1, or a group formed by means of dehydrogenation of a hydroxy-containing compound B2. The compound has the special effects of having a strong transdermal property, controlled drug release, high efficacy, etc.

Abstract: A control device for controlling a pneumatic component includes a compressed air supply circuit for connecting to an inlet of the pneumatic component. The circuit includes a normally closed monostable valve having an inlet for connecting to a compressed air source and an outlet for connecting to the pneumatic component, and a bistable directional valve having both a first port for connecting to the compressed air source and also a second port connected to a first port of a normally passing monostable directional valve, the monostable directional valve having a second port connected to a pneumatic control port of the monostable valve.

Abstract: A Venturi type ejector having a feed duct for feeding fluid under pressure with the duct extending along a central axis. A first expansion chamber is connected to the feed duct; a first mixing chamber is connected to the expansion chamber; a first suction chamber is connected to the mixing chamber; and an exhaust chamber is connected to the first mixing chamber. The ejector where the fluid under pressure penetrates into the first expansion chamber along a plurality of directions extends in a plane that is substantially orthogonal to the central axis. A vacuum generator includes such an ejector.

Abstract: A vacuum gripper device including at least one suction cup including a fastener body from which there extends an elastically deformable skirt having a free annular edge for coming into contact with an object to be grasped. The suction cup includes at least one electrically conductive track secured at least to the skirt. The conductive track is made of a material that is electrically conductive and elastically deformable so as to deform together with the skirt. The device includes an electronic processor circuit that is connected electrically to two connection pads belonging to the conductive track and that is arranged to monitor an electrical property of the conductive track, which electrical property varies with the deformation of the conductive track, and to compare that property with reference data so as to anticipate a failure of the suction cup.

Abstract: A vacuum chamber for a gripper including at least one fastener plate and at least one pneumatic accessory fastened in a perforation in the fastener plate. The pneumatic accessory is held in the perforation by an elastically deformable tubular interface including an external groove in which the periphery of the perforation is received so as to provide sealing between the plate and the interface, the interface defining a channel extending between a first end of the interface extending inside the chamber and a second end extending outside the chamber, at least a portion of the pneumatic accessory being inserted in the channel of the interface.

Abstract: A fluid circulation device having at least one fluid circulation tube, a first coupling sealingly coupled to a first end of the tube and a second coupling sealingly coupled to a second end of the tube in such a way as to allow the circulation of fluid between said two couplings via the tube. The device further has separate electronic elements. The tube has at least one conductor track extending along an outer surface of the tube. The track is suitable for transmitting at least one signal and arranged to engage with the abovementioned electronic elements.

Abstract: A fluid circulation device having at least one fluid circulation tube, a first coupling sealingly coupled to a first end of the tube and a second coupling sealingly coupled to a second end of the tube in such a way as to allow the circulation of fluid between said two couplings via the tube. The device further has separate electronic elements. The tube has at least one conductor track extending along an outer surface of the tube. The track is suitable for transmitting at least one signal and arranged to engage with the abovementioned electronic elements.

Abstract: Disclosed are antibodies (immunoglobulins) and fragments thereof that hydrolyze or bind polypeptide antigens belonging to Staphyloccus aureus, hepatitis C virus, human immunodeficiency virus and Alzheimer's disease. Also disclosed are novel methods to improve the antigen reactivity of the immunoglobulins and to treat a pathophysiological condition using the immunoglobulins as therapeutics.

Abstract: A heat insulator including a porous sintered body having a porosity of 70 vol % or more, pores having a pore size of more than 1000 ?m in a proportion of 10 vol % or less of all pores and pores having a pore size of 0.8 ?m or more and less than 10 ?m occupy 50 vol % or more and 80 vol % or less of pores having a pore size of 1000 ?m or less, while pores having a pore size of 0.01 ?m or more and less than 0.8 ?occupy 10 vol % or more and 30 vol % or less pores having a pore size of 1000 ?m or less. The porous sintered body is formed from MgAl2O4 raw material and includes a fibrous layer formed from inorganic material fibers, the heat conductivity of the heat insulator at 1000° C. or more and 1500° C. or less being 0.40 W/m·K) or less.

Abstract: A modular vacuum gripper having a first plate, a second plate provided with at least one downstream orifice, framework members, assembly device for assembling the first plate, the second plate and the framework members, at least one upstream orifice situated on one of the walls of the vacuum gripper, sealing device, vacuum generation device adapted to suck out the air contained inside the vacuum gripper via the upstream orifice, and at least one deformable element extending over the second plate so as to form a sealed contact surface with the part when the air contained inside the vacuum gripper is sucked out.

Abstract: Solid-supported trithiol compounds are prepared. The solid-supported trithiol compounds have formula (I): in which R is a linker moiety, X is a solid support, and n?1. The compounds of formula (I) may be incorporated into methods for removing heavy metals from solutions and into batch systems or filtration apparatus that remove heavy metals from solutions.

Abstract: A modular vacuum gripper having a first plate, a second plate provided with at least one downstream orifice, framework members, assembly device for assembling the first plate, the second plate and the framework members, at least one upstream orifice situated on one of the walls of the vacuum gripper, sealing device, vacuum generation device adapted to suck out the air contained inside the vacuum gripper via the upstream orifice, and at least one deformable element extending over the second plate so as to form a sealed contact surface with the part when the air contained inside the vacuum gripper is sucked out.

Abstract: Applicants have disclosed a process for fusing a biocompatible glass to a metal substrate. In the preferred embodiment, the process comprises: grit blasting a metallic substrate (e.g., titanium) to remove a surface layer of the metal; after blasting, cleaning the abrasion residue off the surface layer; blending a solvent to use as a suspension agent; creating a suspension of biocompatible and bioactive glass-coating powders in the solvent solution; depositing the suspension onto the metallic substrate; drying thoroughly the suspension-coated metallic substrate; inserting the dried, coated substrate into a non-reactive chamber, purging the chamber with an inert gas, such as pure argon; and firing the metallic substrate, inside the furnace, in the inert gas. This process forms a robust fusion between the biocompatible glass and titanium, according to preliminary test results. This process can be used for various medical and dental devices, including implants and onplants.

Abstract: A vacuum generator module having a substantially rectangular box housing electronic controls for controlling and monitoring the operation of pneumatic vacuum generators and their electrical connections with an electrical power supply and external control members, including an input connector and an output connector installed in one of the faces of the box. The first module is a master module that includes a microcontroller adapted to the communications protocol first of a fieldbus present in a vacuum handling machine incorporating the first module, and secondly of a bus that is dedicated to the other modules. Each of the other modules is a slave module including a microcontroller adapted to the communications protocol of the dedicated bus.

Abstract: One aspect of the heat insulator of the present invention includes a porous sintered body having a porosity of 70 vol % or more and less than 91 vol %, and pores having a pore size of 0.8 ?m or more and less than 10 ?m occupy 10 vol % or more and 70 vol % or less of the total pore volume, while pores having a pore size of 0.01 ?m or more and less than 0.8 ?m occupy 5 vol % or more and 30 vol % or less of the total pore volume. The porous sintered body is formed from an MgAl2O4 (spinel) raw material and fibers formed of an inorganic material, the heat conductivity of the heat insulator at 1000° C. or more and 1500° C. or less is 0.40 W/(m·K) or less, and the weight ratio of Si relative to Mg in the porous sintered body is 0.15 or less.