Patents Assigned to Curators of the University
  • Patent number: 8501319
    Abstract: A composite material that includes a dopant comprised of pre-formed, three dimensional assemblies of skeletal structures that are comprised of solgel derived nanoparticles. The composite material includes a chemically bonded, in situ formed, polymer coating that at least partially coats mesoporous surfaces of the nanoparticles to provide enhancement of random dispersion of the dopant and to minimize or avoid agglomeration. Further, the polymer may be functionalized or the mesoporous surfaces of the nanoparticles may be treated to enable stronger chemical bonding between the dopant and the polymer.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: August 6, 2013
    Assignee: The Curators of the University of Missouri, University of Missouri System, Office of Technology and Special Projects
    Inventors: Nicholas Leventis, Chariklia Sotiriou-Leventis
  • Publication number: 20130190542
    Abstract: Activated carbon materials and methods of producing and using activated carbon materials are provided. In particular, biomass-derived activated carbon materials and processes of producing the activated carbon materials with prespecified surface areas and pore size distributions are provided. Activated carbon materials with preselected high specific surface areas, porosities, sub-nm (<1 nm) pore volumes, and supra-nm (1-5 nm) pore volumes may be achieved by controlling the degree of carbon consumption and metallic potassium intercalation into the carbon lattice during the activation process.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 25, 2013
    Applicant: The Curators of the University of Missouri
    Inventor: The Curators of the University of Missouri
  • Patent number: 8481066
    Abstract: A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B2O3, and two or more other oxides, wherein the scaffold body has a porosity between about 15 and about 90 vol %.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: July 9, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, Steven B. Jung, Roger F. Brown
  • Patent number: 8482602
    Abstract: Non-destructive imaging of an object. An imaging head supported on a rotatable arm samples an electric field scattered by the object at a plurality of locations as the arm rotates about a central axis, with the locations corresponding to a defined spatial domain located remotely from the object. One or more processors execute computer-readable instructions for controlling rotation of the arm and generating a multi-dimensional profile representative of the object in the defined spatial domain based on the sampling.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: July 9, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: David Johannes Pommerenke, Reza Zoughi, Mohammad Tayeb Ghasr, Joseph Tobias Case, Andrew Dale McClanahan, Kyle Lee Guinn
  • Patent number: 8481622
    Abstract: An improved soybean oil ester based epoxy resin and method of making the same is disclosed. A transesterification step is employed to liberate glycerol and to form new fatty acid esters with additional double bonds. The resulting fatty acid esters containing one or more double bonds are epoxidized by reacting with epoxidation reagent. The epoxidized esters serve as monomers in an epoxy resin system, which may be used to manufacture composite materials with improved mechanical properties as compared to materials obtained from epoxidized triglycerides. The soybean based epoxy resin may be used as low-cost and biocompatible coating materials for food and beverage cans.
    Type: Grant
    Filed: September 1, 2007
    Date of Patent: July 9, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Virgil Flanigan, Shubhen Kapila, K. Chandrashekhara, Rachadaporn Seemamahannop, Arun Garg, Surya Misra
  • Patent number: 8475230
    Abstract: An abrasive cutting or drilling system, apparatus and method, which includes an upstream supercritical fluid and/or liquid carrier fluid, abrasive particles, a nozzle and a gaseous or low-density supercritical fluid exhaust abrasive stream. The nozzle includes a throat section and, optionally, a converging inlet section, a divergent discharge section, and a feed section.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: July 2, 2013
    Assignees: The Curators of the University of Missouri, Regency Technologies LLC
    Inventors: David Archibold Summers, Klaus Hubert Woelk, Kenneth Doyle Oglesby, Grzegorz Galecki
  • Publication number: 20130164732
    Abstract: The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst.
    Type: Application
    Filed: December 7, 2012
    Publication date: June 27, 2013
    Applicant: The Curators of the University of Missouri
    Inventor: The Curators of the University of Missouri
  • Patent number: 8470459
    Abstract: The present invention describes processes for coating substrates with a nanocomposite SiCON material. In addition, the present invention describes the dielectric nanocomposite coatings.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: June 25, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Shubhra Gangopadhyay, Maruf Hossain, Keshab Gangapadhyay
  • Patent number: 8471072
    Abstract: The invention provides processes for preparing soy-based oligomeric polyols or substituted oligomeric polyols, as well as urethane bioelasteromers comprising the oligomeric polyols or substituted oligomeric polyols.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: June 25, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Galen Suppes, Zuleica Lozada, Arnold Lubguban
  • Publication number: 20130150251
    Abstract: The present invention relates to compositions and methods useful for analyzing lariat RNA, which plays a role in the regulation of gene expression. A sample of RNA is specifically treated to remove linear mRNA and enrich for lariat RNA. The enriched lariat RNA sample may be analyzed further to identify introns, branch point sequences, alternative splicing patters, and gene transcription levels. The enriched lariat RNA sample may also be exploited as a detection or compound screening tool, as well as other uses.
    Type: Application
    Filed: October 29, 2012
    Publication date: June 13, 2013
    Applicant: The Curators of the University of Missouri
    Inventor: The Curators of the University of Missouri
  • Publication number: 20130115328
    Abstract: Disclosed are methods and compositions for reducing E. coli O157:H7 colonization and shedding in ruminant animals. In certain aspects, methods are provided comprising delivering microencapsulated probiotic bacteria to the gastrointestinal tract of a ruminant animal. Microencapsulated probiotics for delivery to the gastrointestinal tract of a ruminant animal in order to reduce E. coli O157:H7 shedding are also provided.
    Type: Application
    Filed: July 26, 2012
    Publication date: May 9, 2013
    Applicant: The Curators of the University of Missouri
    Inventors: Azlin Mustapha, Monty Kerley, Juhee Ahn
  • Patent number: 8435783
    Abstract: The invention provides engineered plant minichromosomes generated by telomere mediated truncation of native chromosomes. These minichromosomes are faithfully transmitted from one generation to the next and provide an ideal platform for breeding genes into desired plant varieties with out problems, such as linkage drag, associated with standard breeding methods.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: May 7, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Weichang Yu, Juan M. Vega, James Birchler
  • Publication number: 20130104909
    Abstract: The present disclosure provides a surgical drape for providing a sterile field around the vaginal area of a patient during vaginal surgical procedures. In various embodiments the drape comprises a main body and an access opening centrally disposed within the main body. The drape additionally includes a plurality of pleats disposed along opposing lateral side portions of main body. The pleats are structured and operable to allow the drape to be contoured around the patient's abdomen, pelvis and legs, and to provide stability to the drape such that the drape will not be easily displaced from the patient. Furthermore, the drape includes a plurality of equipment retention devices disposed on the main body that are structured and operable to removably retain surgical equipment during the respective surgical procedure.
    Type: Application
    Filed: November 1, 2012
    Publication date: May 2, 2013
    Applicant: The Curators of the University of Missouri
    Inventor: The Curators of the University of Missouri
  • Patent number: 8431349
    Abstract: Disclosed are antibodies and methods for detecting pregnancy in an animal. In certain aspects antibodies used binds immunologically to at least two PAGs selected from PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 and PAG21. Antibody encoding nucleic acids are also provided, as are kits, methods of use and additional antibody related compositions.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: April 30, 2013
    Assignees: Monsanto Technology LLC, The Curators of the University of Missouri
    Inventors: Nagappan Mathialagan, Robert M. Roberts, Michael F. McGrath, Jonathan Green
  • Patent number: 8426154
    Abstract: Methods and immunoassays for diagnosing a bite or sting of a venomous organism in a patient having symptoms consistent with such a bite or sting are provided. A sample of venom is collected from the area of the suspected bite or sting using a swab and then contacted with an antibody that specifically binds to an antigenic site on venom present in the sample. Binding is then detected. The invention is illustrated by examples showing diagnosis of brown recluse spider bite, distinguishing it from other diagnoses with which it is often confused. This extremely sensitive test can detect venom antigens down to about 20 picograms even after the sample has been shipped and stored for periods of up to three weeks during the summer.
    Type: Grant
    Filed: April 8, 2010
    Date of Patent: April 23, 2013
    Assignees: SpiderTech, a Division of Stoecker & Associates, a Subsidiary of The Dermatology Center, LLC., The Regents of the University of Michigan, Office of Technology Transfer, The Curators of the University of Missouri, University Hall, The United States of America as Represented by the Secretary of the Air Force, Directorate of Intellectual Property Law
    Inventors: William V. Stoecker, Hernan F. Gomez, Jonathan A. Green, David L. McGlasson
  • Publication number: 20130084248
    Abstract: The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. In preferred embodiments, the coating consists of material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material.
    Type: Application
    Filed: November 19, 2012
    Publication date: April 4, 2013
    Applicant: The Curators of the University of Missouri
    Inventor: The Curators of the University of Missouri
  • Patent number: 8397553
    Abstract: A flow controller for use with a liquid chromatography detector. The flow controller includes a flow channel comprising an inlet portion, a control channel portion in communication with the inlet portion, and an outlet portion in communication with said control channel portion. The control channel portion has a cross-sectional area smaller than a cross-sectional area of a drift tube of the liquid chromatography detector for channeling the flow of droplets through the smaller cross-sectional area. The flow controller is shaped and sized to reduce pressure fluctuations and turbulence in the droplet stream of the liquid chromatography detector.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: March 19, 2013
    Assignees: The Curators of the University of Missouri, W.R. Grace & Co.-Conn
    Inventors: Zhi Xu, Rakesh Bose, James M. Anderson
  • Patent number: 8399241
    Abstract: Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: March 19, 2013
    Assignees: Whitehead Institute for Biomedical Research, The Curators of the University of Missouri
    Inventors: Susan L. Lindquist, Aaron D. Gitler, Anil Cashikar, Antony A. Cooper, Cole M. Haynes
  • Patent number: 8394711
    Abstract: Various embodiments of the present disclosure provide a method of simultaneously co-doping a wide band gap material with p-type and n-type impurities to create a p-n junction within the resulting wide band gap composite material. The method includes disposing a sample comprising a dopant including both p-type and n-type impurities between a pair of wide band gap material films and disposing the sample between a pair of opposing electrodes; and subjecting the sample to a preselected vacuum; and heating the sample to a preselected temperature; and applying a preselected voltage across the sample; and subjecting the sample to at least one laser beam having a preselected intensity and a preselected wavelength, such that the p-type and n-type impurities of the dopant substantially simultaneously diffuse into the wide band gap material films resulting in a wide band gap compound material comprising a p-n junction.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: March 12, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Mark A. Prelas, Tushar K. Ghos, Robert V. Tompson, Jr., Dabir S. Viswanath, Sudarshan Loyalka
  • Patent number: 8376956
    Abstract: A detector located on a positioning tray has a plurality of colored caps placed by a subject being tested. Each cap has a unique resonant circuit which is selectively energized to indicate cap position to the detector so that color discrimination of the subject may be determined.
    Type: Grant
    Filed: January 8, 2008
    Date of Patent: February 19, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Carl J. Bassi, Michael Howe, Wayne Garver