Patents Assigned to Curators of the University
  • ENGINEERED COMESTIBLE MEAT
    Publication number: 20130029008
    Abstract: Provided are engineered meat products formed as a plurality of at least partially fused layers, wherein each layer comprises at least partially fused multicellular bodies comprising non-human myocytes and wherein the engineered meat is comestible. Also provided are multicellular bodies comprising a plurality of non-human myocytes that are adhered and/or cohered to one another; wherein the multicellular bodies are arranged adjacently on a nutrient-permeable support substrate and maintained in culture to allow the multicellular bodies to at least partially fuse to form a substantially planar layer for use in formation of engineered meat. Further described herein are methods of forming engineered meat utilizing said layers.
    Type: Application
    Filed: July 26, 2012
    Publication date: January 31, 2013
    Applicant: The Curators of the University of Missouri
    Inventors: Gabor FORGACS, Francoise MARGA, Karoly Robert JAKAB
  • Compounds for treatment of copper overload
    Patent number: 8357349
    Abstract: The present invention provides compounds, pharmaceutical compositions, and methods that can be used to treat pathologies that are due to copper overload or to the presence of reactive oxygen species.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: January 22, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Kavita K. Katti, Kannan Raghuraman, Stan W. Casteel, Kattesh V. Katti
  • Scaffold for bone and tissue repair in mammals
    Patent number: 8353966
    Abstract: A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: January 15, 2013
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, Steven B. Jung
  • Methods and system for modeling network traffic
    Patent number: 8352392
    Abstract: A method and system are provided for modeling network traffic in which an artificial neural network architecture is utilized in order to intelligently and adaptively model the capacity of a network. Initially, the network traffic is decomposed into a plurality of categories, such as individual users, application usage or common usage groups. Inputs to the artificial neural network are then defined such that a respective combination of inputs permits prediction of bandwidth capacity needs for that input condition. Outputs of the artificial neural network are representative of the network traffic associated with the respective inputs. For example, a plurality of bandwidth profiles associated with respective categories may be defined. An artificial neural network may then be constructed and trained with those bandwidth profiles and then utilized to relate predict future bandwidth needs for the network.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: January 8, 2013
    Assignees: The Boeing Company, The Curators of the University of Missouri
    Inventors: Douglas K. Swift, Cihan H. Dagli
  • HOMOGENEOUS MESOPOROUS NANOENERGETIC METAL OXIDE COMPOSITE FABRICATION METHODS
    Publication number: 20130000800
    Abstract: The invention provides methods for making homogeneous metal oxide nanoenergetic composites. A method of the invention forms a metal oxide nanostructure via a sol-gel process with surfactant templating. Metal nanoparticles are introduced into the metal oxide nanostructure via wet impregnation.
    Type: Application
    Filed: September 7, 2012
    Publication date: January 3, 2013
    Applicant: The Curators of the University of Missouri
    Inventors: Shubhra Gangopadhyay, Daniel Tappmeyer, Andrey Bezmelnystin, Rajagopalan Thiruvengadathan, Rajesh Shende, Bhushan Mehendale, Steven Apperson, Syed Barizuddin, Keshab Gangopadhyay
  • Mass sensing device for liquid environment
    Patent number: 8336373
    Abstract: A device for sensing a mass in a liquid environment including a resonator comprising a piezo layer having a top electrode and a bottom electrode, a sensing surface located adjacent and opposite the top electrode, the resonator and the sensing surface defining a gap therebetween, and a post attached to the sensing surface and the resonator.
    Type: Grant
    Filed: April 7, 2010
    Date of Patent: December 25, 2012
    Assignee: Curators of the University of Missouri
    Inventor: Jae Wan Kwon
  • Method and system for non-invasive optical blood glucose detection utilizing spectral data analysis
    Patent number: 8340738
    Abstract: Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. A variety of techniques are disclosed for improving signal-to-noise ratio in the acquisition of spectral data and calculating attenuance of light attributable to blood in a sample. Disclosed techniques include (1) using a standard deviation operation in conjunction with the logarithm function, (2) using a normalization factor, (3) using a ratio factor, (4) accounting for the effect of temperature on various system components such as resistors, and (5) accounting for dark current in a light detector by performing a calibration.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: December 25, 2012
    Assignee: The Curators of The University of Missouri
    Inventor: Zhi Xu
  • Controlling vessel growth and directionality in mammals and implantable material
    Patent number: 8337875
    Abstract: A method for directing vessel growth toward a blood-deficient site in a mammal comprising implanting into the mammal an assembly of at glass fibers to form a vascular bridge with a first end of the vascular bridge in contact with the blood-deficient site and a second end of the vascular bridge remote from the blood-deficient site. Over time the bridge biodegrades and promotes vascularity in the direction of the bridge.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: December 25, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Steven B. Jung, Delbert E. Day
  • Stabilized, biocompatible gold nanoparticles and enviro-friendly method for making same
    Patent number: 8333994
    Abstract: The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. In methods of the invention, an aqueous solution containing gold salts is mixed with polyphenols- or flavanoids-rich plant material. In preferred embodiment methods of making, an aqueous solution containing gold salts is provided. The aqueous solution is mixed with black tea, turmeric, curcumin or cinnamon or a similar naturally occurring polyphenols- or flavanoids-rich plant material. The gold salts react to form biocompatible gold nanoparticles that are stabilized with a coating of the polyphenols- or flavanoids-rich plant material.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: December 18, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Kattesh V. Katti, Raghuraman Kannan, Kavita K. Katti, Satish Kumar Nune
  • METHOD AND APPARATUS FOR JET-ASSISTED DRILLING OR CUTTING
    Publication number: 20120309268
    Abstract: An abrasive cutting or drilling system, apparatus and method, which includes an upstream supercritical fluid and/or liquid carrier fluid, abrasive particles, a nozzle and a gaseous or low-density supercritical fluid exhaust abrasive stream. The nozzle includes a throat section and, optionally, a converging inlet section, a divergent discharge section, and a feed section.
    Type: Application
    Filed: August 20, 2012
    Publication date: December 6, 2012
    Applicants: Regency Technologies LLC, The Curators of the University of Missouri
    Inventors: David Archibold Summers, Klaus Hubert Woelk, Kenneth Doyle Oglesby, Grzegorz Galecki
  • Method and apparatus for predicting soybean seed resistance based on near-infrared spectroscopy
    Patent number: 8321135
    Abstract: The present invention relates to a method and apparatus for predicting the resistance of soybean seed samples to infection by soybean cyst nematode parasites using near-infrared spectroscopy and discriminant analysis.
    Type: Grant
    Filed: February 19, 2002
    Date of Patent: November 27, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Christopher M. Fender, David A. Sleper
  • Categorically ranking animals for feed efficiency
    Patent number: 8319008
    Abstract: The invention provides methods for managing livestock for breeding or production based on one or more measurements of mitochondrial function. Measurement of mitochondrial function may also be correlated with a calculated or known feed efficiency of livestock animals to yield a predicted feed efficiency for the animal. The invention overcomes deficiencies associated with phenotypic assays for predicted breeding and production value.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: November 27, 2012
    Assignee: The Curators of The University of Missouri
    Inventors: Monty S. Kerley, William Kolath, Joseph Golden
  • Device for transfecting cells using shock waves generated by the ignition of nanoenergetic materials
    Patent number: 8303522
    Abstract: A miniature device for generating shock waves using the energy of combustion of a nanoenergetic material and directing the shock waves into biological tissues is described.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: November 6, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Steve Apperson, Shubhra Gangopadhyay, Luis Polo-Parada, Andrey Bezmelnitsyn, Keshab Gangopadhyay
  • Homogeneous mesoporous nanoenergetic metal oxide composites and fabrication thereof
    Patent number: 8293040
    Abstract: The invention provides homogeneous mesoporous metal oxide nanoenergetic composites. A composite of the invention has a regular and uniform nanostructure of metal oxide, which is structured by a surfactant. Metal fuel nanoparticles are homogenously distributed through the regular and uniform nanostructure. The invention further provides methods for making homogeneous metal oxide nanoenergetic composites. A method of the invention forms a metal oxide nanostructure via a sol-gel process with surfactant templating. Metal nanoparticles into the metal oxide nanostructure via wet impregnation.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: October 23, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Shubhra Gangopadhyay, Daniel Tappmeyer, Andrey Bezmelnytsin, Rajagopalan Thiruvengadathan, Rajesh Shende, Bhusban Mehendale, Steven Apperson, Syed Barizuddin, Keshab Gangopadhyay
  • Photo-acoustic detection device and method
    Patent number: 8293176
    Abstract: An example method for detecting an analyte in a sample of a bodily fluid includes the steps of exposing the bodily fluid sample to electromagnetic energy to cause a thermoelastic expansion in the analyte, and detecting a photoacoustic signal in the sample that results from the thermoelastic expansion.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: October 23, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: John A. Viator, Paul S. Dale, Ryan M. Weight, Peter Sutovsky
  • Assemblies for use in evaluating subsurface contamination, and related methods
    Patent number: 8286511
    Abstract: A method is provided for determining the presence and/or concentration of at least one contaminant in a subsurface at a test site. The method generally includes inserting a sampling assembly into at least one tree at the test site, processing at least part of the sampling assembly to determine if a contaminant is present in the at least one tree, and then correlating the presence and/or concentration of the contaminant in the at least one tree to presence and/or concentration of the contaminant in the subsurface. The sampling assembly is operable to sorb at least one contaminant located within the at least one tree to at least part of the sampling assembly. The sampling assembly may include a solid phase microextraction (SPME) sampling assembly having a SPME sampling device and a support configured to help position the SPME sampling device within a tree for sampling operation.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: October 16, 2012
    Assignee: The Curators of the University of Missouri
    Inventor: Joel G. Burken
  • Scaffolds with trace element for tissue regeneration in mammals
    Patent number: 8287896
    Abstract: A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: October 16, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Steven B. Jung, Delbert E. Day
  • System and method for linking a web-based resource with an electronic medical record
    Patent number: 8260637
    Abstract: A data processing system and method that, in some cases, include an EMR system and a web server. In some cases, the EMR system includes a plurality of electronic medical records for a plurality of patients. One or more of the electronic medical records may include a URL or HTTP Post message that defines a path to a web-based resource, such as a treatment algorithm or medical calculator. In some embodiments, the URL and/or HTTP Post message is constructed based on information in a patient's medical record.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: September 4, 2012
    Assignee: The Curators of the University of Missouri
    Inventors: Karl M. Kochendorfer, Jared S. Coberly
  • Method and apparatus for jet-assisted drilling or cutting
    Patent number: 8257147
    Abstract: An abrasive cutting or drilling system, apparatus and method, which includes an upstream supercritical fluid and/or liquid carrier fluid, abrasive particles, a nozzle and a gaseous or low-density supercritical fluid exhaust abrasive stream. The nozzle includes a throat section and, optionally, a converging inlet section, a divergent discharge section, and a feed section.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: September 4, 2012
    Assignees: Regency Technologies, LLC, The Curators of the University of Missouri
    Inventors: David Archibold Summers, Klaus Hubert Woelk, Kenneth Doyle Oglesby, Grzegorz Galecki
  • Methods and systems for biclustering algorithm
    Publication number: 20120221573
    Abstract: Methods and systems for improved unsupervised learning are described. The unsupervised learning can consist of biclustering a data set, e.g., by biclustering subsets of the entire data set. In an example, the biclustering does not include feeding know and proven results into the biclustering methodology or system. A hierarchical approach can be used that feeds proven clusters back into the biclustering methodology or system as the input. Data that does not cluster may be discarded. Thus, a very large unknown data set can be acted on to learn about the data. The system is also amenable to parallelization.
    Type: Application
    Filed: January 30, 2012
    Publication date: August 30, 2012
    Applicant: The Curators of the University of Missouri
    Inventors: Donald Coolidge Wunsch, II, Rui Xu, Sejun Kim