Patents Assigned to D
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Patent number: 11434131Abstract: Method of manufacturing a micromechanical component intended to cooperate with another micromechanical component, the method comprising the steps of providing a substrate, forming a mould on said substrate, said mould defining sidewalls arranged to delimit said micromechanical component, providing particles on at least said sidewalls, depositing a metal in said mould so as to form said micromechanical component, and liberating said micromechanical component from said mould and removing said particles.Type: GrantFiled: February 17, 2021Date of Patent: September 6, 2022Assignee: CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA—RECHERCHE ET DÉVELOPPEMENTInventors: Nicolas Blondiaux, Raphaël Pugin
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Patent number: 11433794Abstract: A headrest for a vehicle seat, comprising a support configured to receive and support the head of a seat occupant, and, connected to said support, at least one speaker system comprising: a speaker unit comprising a loudspeaker received in an airtight housing, a guide system for guiding the speaker unit relative to the support of the headrest, said guide system being configured so that the speaker unit can transition from a first usage position to a second usage position, and vice versa, the transition from the first usage position to the second usage position, and vice versa, corresponding to a movement combining a translation of the speaker unit and a rotation of the speaker unit.Type: GrantFiled: December 16, 2019Date of Patent: September 6, 2022Assignee: FAURECIA Sièges d'AutomobileInventor: Stéphane Soltner
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Patent number: 11434246Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.Type: GrantFiled: January 5, 2021Date of Patent: September 6, 2022Assignee: EISAI R&D MANAGEMENT CO., LTD.Inventors: Wanjun Zheng, Xiaojie Zhu, Hong Du, Maarten Postema, Yimin Jiang, Jing Li, Robert Yu, Hyeong-Wook Choi, Jaemoon Lee, Francis G. Fang, Daniel Custar
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Patent number: 11433261Abstract: The present invention relates to a face mask comprising (a) a mask body portion configured to surround the mouth and at least part of the nose of a wearer; (b) a sealed compressible cushion formed on the inner face of said mask body portion wherein the middle of said cushion is placed in close proximity to the middle of the superior perimeter of said mask body portion, and wherein said cushion is at least partially filled with a fluid.Type: GrantFiled: June 10, 2014Date of Patent: September 6, 2022Assignees: PREVENTECH LTD., DEA R&D LTD.Inventors: Reuven Fichman, Eliahu Uri Groomi Cohen, Ariel Pinhas Ben-Rey, Guy David Robin, Moran Bodas
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Patent number: 11434256Abstract: The present invention relates to an improved process for the preparation of 3?,7?-dihydroxy6?-ethyl-5?-cholan-24-oic acid compound of formula-1, represented by the following structural formula: Formula-1 The present invention also relates to process for the preparation of ethylene diamine and tertiary butyl amine salts of 3?,7?-dihydroxy6?-ethyl-5?-cholan-24-oic acid which are useful in the preparation of pure 3?,7?-dihydroxy6?-ethyl-5?-cholan-24-oic acid.Type: GrantFiled: January 25, 2019Date of Patent: September 6, 2022Assignee: MSN LABORATORIES PRIVATE LIMITED, R&D CENTERInventors: Thirumalai Rajan Srinivasan, Eswaraiah Sajja, Venkata Panakala Rao Gogulapati, Ganapathi Chary Nagunuri
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Publication number: 20220275955Abstract: An air purifier comprising at least one removable particulate filter, a fan or impeller and a motor for driving said fan or impeller, a top and, opposite thereto, a base and means for elevating said base from the ground, at least one side surface connecting said top and base, a base air intake disposed on said base and facing the ground in a working configuration a top air intake on said top and facing away from the ground in a working configuration and an air outlet located on said side surface.Type: ApplicationFiled: October 19, 2020Publication date: September 1, 2022Applicant: Conopco, Inc., d/b/a UNILEVERInventor: Lars Henrik DUNBERGER
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Publication number: 20220274730Abstract: An apparatus for removing goods from a two-part carton having a base and a lid, the base being formed with side walls having external gussets secured against external side faces of the carton, the apparatus including: a lid removal module for engaging the lid and removing it from the carton; expansion members configured to be advanced between the gussets and the external side faces of the carton to remove the gussets from the side faces; engagement members for engaging side walls of the base and drawing them away from the goods and holding them in a position away from the goods; and a goods transfer module for engaging the goods and removing them from the carton.Type: ApplicationFiled: August 7, 2020Publication date: September 1, 2022Applicant: VISY R & D PTY LTDInventors: Michael William Griffith, Kaine Michael Cole, Derek Ian Campbell Ford, Matthew Stevens
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Publication number: 20220276265Abstract: This invention discloses diagnosis of risk of chemotherapy-induced cardiotoxicity by measurement of increased expression of soluble epoxide hydrolase in vitro and in vivo in cells, tissues or animals including measurement of increased levels of soluble epoxide hydrolase metabolites, e.g., 14,15-DHET and 11,12-DHET, in biological fluids. This invention also includes diagnosis of risk of chemotherapy-induced cardiotoxicity by measuring increased levels of oxidative stress in cells, tissues or animals including measurement of increased levels of oxidative stress biomarkers, e.g., 8-isoprostane, in biological fluids. Fatty acid and protein biomarkers to diagnose the risk of chemotherapy-induced cardiotoxicity are detected using various detection methods including mass spectrometry and immunoassay such as ELISA, Western blot analysis or label-free microwell and nanowell technologies.Type: ApplicationFiled: January 28, 2019Publication date: September 1, 2022Applicant: Detroit R & D, Inc.Inventor: Hyesook Kim
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Publication number: 20220273582Abstract: A continuous process for nano-emulsification that is performed by concentration phase inversion in a microfluidic reactor, including the following steps: (a) injection of an aqueous phase into a first microchannel, the first microchannel opening onto a formulation chamber, (b) injection, into a second microchannel, of a fatty phase including one or more fatty substances immiscible in the aqueous phase, and one or more surfactants, the second microchannel opening into the formulation chamber, then (c) mixing of the aqueous phase and the fatty phase in the formulation chamber, then (d) recovering, at the output of the formulation chamber, a suspension including lipid nanocapsules. Also, the lipid nanocapsules obtainable by the process, and the use of the lipid nanocapsules as nanovectors for pharmacologically active ingredients.Type: ApplicationFiled: July 24, 2020Publication date: September 1, 2022Applicants: UNIVERSITÉ D'ANGERS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Brice CALVIGNAC, Jean-Christophe GIMEL, Emilie ROGER, Nicolas ROLLEY, Guillaume LEFEBVRE, Guillaume BASTIAT, Florian FOUCHET, Kévin MATHA
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Publication number: 20220277062Abstract: Methods and devices for spoofing proof authentication of a user by voice to unlock a user device. According to one of its aspects, a method includes performing spoofing proof authentication of a user by voice. According to another aspect, a device is configured for spoofing proof authentication of a user by voice. Implementation of the method provides not only personalized access to the data, but also the highest level of security due to anti-spoofing.Type: ApplicationFiled: March 1, 2021Publication date: September 1, 2022Applicant: ID R&D Inc.Inventor: Konstantin Konstantinovich SIMONCHIK
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Publication number: 20220273850Abstract: A three-dimensional biomaterial including particles encapsulating at least one complement active fragment dispersed therein. Also, a process of manufacturing of the three-dimensional biomaterial with at least one biocompatible and/or resorbable polymer and the particles. The three-dimensional biomaterial is useful for tissue regeneration, especially with regards to dental pulp, dentin, periodontal and gingival tissues, as well as bones tissues.Type: ApplicationFiled: July 31, 2020Publication date: September 1, 2022Applicants: SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Imad ABOUT, Gilles RICHARD, Madison BERGMANN, Charlotte JEANNEAU, Mounir DJOUDI
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Publication number: 20220274957Abstract: The invention relates to benzimidazole-carboxamide 5-HT4 receptor agonist compounds of formula (I) wherein R1 and X are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: January 12, 2022Publication date: September 1, 2022Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: Robert Murray McKinnell, Roland Gendron, Lan Jiang, Seok-Ki Choi, Daniel D. Long, Paul R. Fatheree, Daniel Marquess
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Publication number: 20220272996Abstract: An objective of the disclosure is to provide compositions containing vegetable oils and an anti-oxidant system to prevent oxidation of the triglycerides in the vegetable oil in food products, in particular in products which are often stored for a long time. The antioxidant system should not give an undesired colour, and neither an undesired taste, to a food composition. Additionally, it should be a natural compound and/or common food ingredient, and fitting to the food composition with regard to taste and colour. This has been achieved by providing a food composition containing vegetable oil and apple cider vinegar, wherein the weight ratio of citric acid and malic acid to total organic acids in the apple cider vinegar is more than 2%.Type: ApplicationFiled: February 10, 2022Publication date: September 1, 2022Applicant: Conopco Inc., d/b/a UNILEVERInventors: Marieke Beute, Tjerk Bouman, Alessia Ermacora, Sabrina Silva Paes, Jurek Woller
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Patent number: 11427648Abstract: The present invention relates to the field of diagnostic and treatment of cancer, particularly melanoma, pancreatic cancer, kidney cancer and colon cancer. In particular, the invention relates to an antibody directed specifically to CD146-positive tumors and its applications, particularly for use as a medicament for the prevention and/or treatment of cancer, for use in a method of diagnostic or prognostic of a cancer, or for use as a radiotracer when labelled with a radioactive element.Type: GrantFiled: October 5, 2018Date of Patent: August 30, 2022Assignees: UNIVERSITE D'AIX-MARSEILLE, ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)Inventors: Marcel Blot-Chabaud, Benjamin Guillet, Marie Nollet, Jimmy Stalin, Nathalie Bardin, Françoise Dignat-George
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Patent number: 11428924Abstract: According to one aspect, the invention relates to a device for transporting and controlling light beams for endo-microscopic imaging without a lens on the distal side comprising a single-mode optical fibre bundle (40) on the distal side, wherein each single-mode optical fibre is intended to receive an elementary light source and to emit a light beam at a distal end; a single-mode optical fibre section (50) arranged at the distal end of the optical fibre bundle and intended to receive the light beams emitted by the single-mode optical fibres of the optical fibre bundle; an optical phase control device arranged on the side of the proximal end of the single-mode optical fibres.Type: GrantFiled: April 4, 2017Date of Patent: August 30, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, Ecole Centrale de Marseille (ECM), Université d'Aix-Marseille (AMU)Inventors: Hervé Rigneault, Esben Ravn Andresen, Siddarth Sivankutty
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Patent number: 11429066Abstract: An instantaneous date control device for a timepiece, in particular for a mechanical wristwatch, including: a date disc, a gear train forming a kinematic linkage between the control device and a horological movement of said timepiece, a first mobile including a first toothed wheel driven at a speed of one turn per day and a cam mounted freely rotatably, over a limited angular range and/or in a single direction of rotation, as well as temporarily coupled in rotation to said first toothed wheel, a second mobile including a second toothed wheel driven at a speed of one turn per day, an unlocking and driving yoke carrying a feeler bearing on said cam and a driving finger which can mesh with teeth located on the date disc, an unlocking and driving spring, and a retaining means allowing to secure the angular position of the date disc between two instantaneous jumps.Type: GrantFiled: May 9, 2019Date of Patent: August 30, 2022Assignee: Sociéte anonyme de la manufacture d'horlogerie Audemars Piquet & CieInventors: Gilles Rey-Mermet, Nicolas Goy
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Patent number: 11427948Abstract: A support plate mounted on the inner side wall of an inner drum has a through hole corresponding to drain openings formed in the wall of the drum, and a gap between the support plate and the side wall of the inner drum forms a space for valve plugs of sealing valves to move up and down; a mounting sleeve installed on the upper side of the support plate has an inner through hole coaxially arranged with the through hole in the support plate, so that the valve plugs of the sealing valves are coaxially installed in the inner through hole and can move up and down. A drain opening formed in the side wall of the inner drum is provided with a sealing valve installed on the inner drum via the sealing valve structure.Type: GrantFiled: February 21, 2019Date of Patent: August 30, 2022Assignees: QINGDAO HAIER WASHING MACHINE CO., LTD., QINGDAO HAIER SMART TECHNOLOGY R&D CO., LTD., HAIER SMART HOME CO., LTD.Inventors: Yimin Li, Chunfeng Lao, Xinghui Hao, Di Wu, Peishi Lv
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Patent number: 11427944Abstract: A straight guide rail extending in an X direction is provided in a sewing platform portion for installing in a fixed state a pallet holding an object to be sewn, and first and second sewing machines are provided at left and right sides of the straight guide rail as viewed in the X direction. The first and second sewing machines are both provided with a movement support platform which allow the straight guide rail to reciprocate in the X direction, and the movement support platform is provided with a sewing machine body which is capable of reciprocating in a Y direction. The first and second sewing machines are program controlled in such a manner that any one thereof is capable of moving from one side of the straight guide rail toward the other side beyond a middle section thereof during the sewing operation of the first and second sewing machines.Type: GrantFiled: September 18, 2019Date of Patent: August 30, 2022Assignee: MATSUYA R&D CO., LTD.Inventors: Hidetaka Goto, Tatsuo Sako, Masahi Nakano
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Patent number: 11427806Abstract: The present invention provides a method for producing dopaminergic neuron progenitor cells from pluripotent stem cells, which method comprises the steps of: (i) performing adherent culture of pluripotent stem cells on an extracellular matrix in a medium containing a reagent(s) selected from the group consisting of BMP inhibitor, TGF? inhibitor, SHH signal-stimulating agent, FGF8, and GSK3? inhibitor; (ii) collecting Corin- and/or Lrtm1-positive cells from the cells obtained in Step (i) using a substance which binds to Corin and/or a substance which binds to Lrtm1; and (iii) performing suspension culture of the cells obtained in Step (ii) in a medium containing a neurotrophic factor.Type: GrantFiled: September 4, 2014Date of Patent: August 30, 2022Assignees: Kyoto University, Osaka University, Eisai R&D Management Co., Ltd.Inventors: Jun Takahashi, Daisuke Doi, Bumpei Samata, Kiyotoshi Sekiguchi, Yuichi Ono
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Patent number: D962154Type: GrantFiled: March 10, 2020Date of Patent: August 30, 2022Assignee: Apollo Tyres Global R&D B.V.Inventors: Marko Veselinovic, Jelin Fatima, Ioannis Kostantinou
