Patents Assigned to D
  • Compounds for the treatment of mitochondrial diseases
    Patent number: 10639287
    Abstract: Disclosed is a compound of formula (Ia) for the use thereof in the treatment or prevention of diseases relating to the instability of mitochondrial DNA.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: May 5, 2020
    Assignees: UNIVERSITE PARIS-SUD, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'ANGERS, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS
    Inventors: Agnes Delahodde, Laras Ajeng Pitayu, Enrico Baruffini, Tiziana Lodi, Agnes Rotig, Vincent Procaccio
  • DEMENTIA THERAPEUTIC AGENT COMBINING PYRAZOLOQUINOLINE DERIVATIVE AND MEMANTINE
    Publication number: 20200129488
    Abstract: There is provided a therapeutic agent for Alzheimer's disease for combined use of (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinoline-4(5H)-one represented by formula (I): or a pharmaceutically acceptable salt thereof, and memantine represented by formula (II): or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 30, 2018
    Publication date: April 30, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Mai Miyamoto, Sadaharu Kotani
  • 2-AZABICYCLO HEXANE JAK INHIBITOR COMPOUND
    Publication number: 20200131178
    Abstract: The invention provides a compound of formula 1 or a pharmaceutically-acceptable salt thereof, that is useful as a JAK inhibitor. The invention also provides pharmaceutical compositions comprising the compound, methods of using the compound to treat diseases amenable to a JAK inhibitor, and processes useful for preparing the compound.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 30, 2020
    Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Paul R. Fatheree, Lan Jiang
  • DART GAME APPARATUS
    Publication number: 20200132419
    Abstract: [The present invention is] a dart game apparatus that provides a dart game in which one player successively throws n number of (n=3 or 4) darts D at a dart board 12, having: light sources LS that are disposed around the dart board 12 and emit lights L along the board face of the dart board 12; a plurality of photo-sensors S that are disposed around the dart board 12 at approximately the same height from the dart board 12 in the board thickness direction, and detect the brightness of the lights L emitted from the light sources LS; and a processor that calculates a hit position of a dart D in the dart board 12 based on the brightness of each light. A number of photo-sensors S is n×2.
    Type: Application
    Filed: July 30, 2018
    Publication date: April 30, 2020
    Applicants: Kabushiki Kaisha SEGA Games d/b/a SEGA Games Co., Ltd., Kabushiki Kaisha Dartslive D/B/A Dartslive Co., Ltd.
    Inventors: Hiroshi Takamura, Takayuki Ohnishi
  • DEMENTIA THERAPEUTIC AGENT COMBINING PYRAZOLOQUINOLINE DERIVATIVE AND DONEPEZIL
    Publication number: 20200129501
    Abstract: There is provided a therapeutic agent for Alzheimer's disease and Lewy body dementia for combined use of (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinoline-4(5H)-one represented by formula (1): or a pharmaceutically acceptable salt thereof, and donepezil represented by formula (II): or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 30, 2018
    Publication date: April 30, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Mai Miyamoto, Sadaharu Kotani
  • METHOD FOR CONTINUOUSLY PRODUCING A PATTERN AT THE SURFACE OF A FLEXIBLE SUBSTRATE AND RELATED APPARATUS
    Publication number: 20200131696
    Abstract: The invention relates to a method for continuously producing a pattern at the surface of a flexible substrate, comprising a step of forming a primary pattern by means of an operation of coating said substrate with a hot melt composition that is in the molten state, characterized in that said composition is a reactive polyurethane composition that is moisture crosslinkable to form a thermosetting polyurethane and in that said method comprises, after said coating operation, a step of moisture crosslinking the composition forming the primary pattern to obtain a secondary pattern made of thermosetting polyurethane. The invention also relates to a facility relating to such a method for coating on flexible substrates.
    Type: Application
    Filed: May 2, 2018
    Publication date: April 30, 2020
    Applicant: F.D.S.
    Inventor: Philippe SERRE
  • METHOD AND DEVICE FOR SEGMENTING IMAGES BY AUTOMATIC PROPAGATION INTO AN (N+1)-TH DIMENSION OF AN IMAGE SEGMENTATION INITIALIZED IN DIMENSION N
    Publication number: 20200134846
    Abstract: This method (100) for automatic propagation into an (N+1)-th dimension of an image segmentation initialized in dimension N, N?2, comprises the acquisition (102) of an ordered series of image representations of dimension N and an initial segmentation (104) in dimension N of a region of interest in the first and last image representations of the series, to obtain first and last initial segmentation masks (M0, Mn) of the region of interest. It further comprises an estimation (106) of registration parameters (La, Ld) between the first and last initial segmentation masks, and upward and downward automatic propagations (108) of the initial segmentation, from the first and last image representations, to all the other image representations of the series by step-by-step registration up to the last and first image representations.
    Type: Application
    Filed: July 10, 2018
    Publication date: April 30, 2020
    Applicants: Universite d'Aix Marseille, Centre National de la Recherche Scientifique
    Inventors: Arnaud LE TROTER, David BEN DAHAN, Augustin OGIER
  • Heating and/or cooling device for a motor vehicle seat
    Patent number: 10632879
    Abstract: A motor vehicle seat element successively including: a pad; a heating and/or cooling device including at least one heat and/or cold generation element and at least one heat and/or cold diffusion layer; and a cover.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: April 28, 2020
    Assignee: FAURECIA Sièges d'Automobile
    Inventors: Anne Isabelle Dacosta-Mallet, Samuel Baudu
  • High translucent dental zirconia blank and sintered body
    Patent number: 10631961
    Abstract: A zirconia ceramic body for use with dental prosthetics has an L* value between 10 and 20 for a sample thickness 011 to 1.3 mm in accordance with CIE L*a*b* colorimetric system. The zirconia ceramic body can have between 6-20 wt % or 7.20 wt % of yttria based on total weight percent of the zirconia ceramic body. The zirconia ceramic body is subsequently finally sinterable to produce a translucent zirconia sintered body. In one aspect, the sintered body has a total light transmittance of at least 36% and less than 50% to light with a wavelength of 400 nm, and less than 55% to light with a wavelength of 600 nm, at a thickness of 0.6 mm, measured using a LAMBDA 35 UV/VIS Spectrophotometer manufactured by Perkin Elmer.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: April 28, 2020
    Assignee: B & D Dental Corporation
    Inventors: Yunoh Jung, Daniel Yonil Jung
  • Viral replication inhibitors
    Patent number: 10633378
    Abstract: The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: April 28, 2020
    Assignee: Katholieke Universiteit Leuven, K.U. Leuven R&D
    Inventors: Dorothée Bardiot, Gunter Carlens, Kai Dallmeier, Suzanne Kaptein, Mohamed Koukni, Arnaud Marchand, Johan Neyts, Wim Smets
  • Laser 3D printer
    Patent number: 10632674
    Abstract: A laser 3D printer presents a tubular compartment; a lifting platform engaged in a sliding manner in the tubular compartment; a dispenser for feeding a given amount of powdered material onto the lifting platform; a distributor for distributing the powdered material over the lifting platform; and a laser printing head for sintering the powdered material laid on the lifting platform; the dispenser being defined by two pipes, which are coaxial, are mobile with respect to one another about a rotation axis, and have respective openings configured for facing each other radially so as to define an outlet for the powdered material from the dispenser itself.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: April 28, 2020
    Assignee: 3D4MEC SRL
    Inventors: Giuseppe Corsini, Gabriele Carloni
  • Air conditioning system for an open motorized vehicle
    Patent number: 10632815
    Abstract: An air conditioning system for an open motorized vehicle can include a cab assembly defining an interior volume, the cab assembly includes an enclosed frame configured to be attached to an open vehicle, and an air conditioning unit positioned at least partially within the cab assembly, the air conditioning unit being configured to deliver conditioned air to the interior volume of the cab assembly.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: April 28, 2020
    Assignee: B & D Technologies, LLC
    Inventor: Orvell B. Reynolds
  • Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating induced inflammatory bowel diseases such as crohn's disease
    Patent number: 10632135
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: April 28, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AUVERGNE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, UNIVERSITE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Julie Bouckaert, Sebastien Gouin, Adeline Sivignon, Arlette Darfeuille-Michaud, Rostyslav Bilyy, Dimitri Alvarez-Dorta, Nao Yamakawa, Tetiana Dumych
  • Flexible peltier device and temperature regulation apparatus
    Patent number: 10636952
    Abstract: A flexible Peltier device in which emitting heat conversion properties between Peltier elements and an object transferring heat may be improved and a flexible heat-emitting sheet having the Peltier elements bonded thereto may be bent without worrying the separation there between. A flexible Peltier device includes a single or plural Peltier element which is disposed on one surface side of a heat-emitting sheet having flexibility made from heat-conductive rubber containing a heat conductive filler and each semiconductor element which has a heating side and a cooling side and composes the Peltier element at least one of the heating side and the cooling side is bonded integrally to the heat-emitting sheet by a direct covalent bond and/or by an indirect covalent bond through a molecular adhesive at active groups existing on each other surfaces.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: April 28, 2020
    Assignee: ASAHI FR R&D CO., LTD.
    Inventors: Kazuhisa Takagi, Koichi Abe, Nobuyoshi Watanabe, Syuhei Toyoshima
  • Window wiping device comprising means for limitation of a curvature acquired by a flexible washing liquid feed tube
    Patent number: 10632974
    Abstract: Window wiping device for a motor vehicle comprising at least one link (2, 3), a mobile arm (6) adapted to be mounted on the vehicle by said link (2, 3) and effect an angular to-and-fro movement (A), a flexible washing liquid feed tube (16), rigidly fastened to said mobile arm (6), which device is characterized in that it further comprises a means (20) for limitation of a curvature assumed by said flexible feed tube (16) configured to surround the flexible feed tube (16) so as to prevent it cracking.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: April 28, 2020
    Assignee: Valeo Systèmes d'Essuyage
    Inventor: Jean-Michel Jarasson
  • Motorized device with reciprocating motion of a locomotion member and associated control method
    Patent number: 10633089
    Abstract: A motorized device capable of moving in a fluid and including one or more locomotor systems, each having at least one drive assembly linked to at least one locomotion member and a motor controlled by a voltage. The frequency of a reciprocating motion of the drive assembly matches the resonant frequency of the locomotion member linked to a non-movable portion by at least one prestrained elastic member. The instantaneous amplitude of the reciprocating motion of the drive assembly is adjusted to control the average position and the maximum amplitude of the reciprocating motion of the locomotion member. The drive assembly includes at least one speed reducer for reducing the speed of rotation of the motor. When the motor is operating at its maximum mechanical power, the speed of rotation transmitted to the at least one locomotion member is reduced to match the resonance frequency.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: April 28, 2020
    Assignee: OFFICE NATIONAL D'ÉTUDES ET DE RECHERCHES AÉROSPATIALES
    Inventors: Thierry Le Moing, Mathieu Rognant
  • Snorkel connection hose for a vehicle
    Patent number: D882635
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: April 28, 2020
    Assignee: Safari R&D Pty Ltd
    Inventor: Dean Wickes
  • Air intake snorkel for a vehicle
    Patent number: D882636
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: April 28, 2020
    Assignee: Safari R&D Pty Ltd
    Inventor: Dean Wickes
  • Cab roof
    Patent number: D882647
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: April 28, 2020
    Assignee: B & D Technologies, LLC
    Inventors: Orvell B. Reynolds, Devon Fairhurst
  • Container
    Patent number: D883096
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: May 5, 2020
    Assignee: LES ÉQUIPMENTS D'ÉRABLIÈRE C.D.L. INC.
    Inventor: Maxim Thibault