Patents Assigned to D
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Publication number: 20240252406Abstract: A cosmetic composition comprises resorcinol, functionalized heteroaromatic compound, and a retinoic acid precursor. An effective way to improve the color stability of compositions comprising such skin benefit agents is desired. It has been found that alkylresorcinol, functionalized heteroaromatic compound, and retinoic acid precursor in combination with antioxidant, compatible oil and emulsifying polymer provide for improved color stability of the composition. The inventive composition thus relates to a composition comprising a synergistic combination of emulsifying polymer with alkylresorcinols, functionalized heteroaromatic compounds CA and retinoidsin combination with antioxidant and compatible oil.Type: ApplicationFiled: May 18, 2022Publication date: August 1, 2024Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Hasiba BEKTO, Lei HUANG
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Publication number: 20240254412Abstract: A machine dishwash detergent composition comprising from 0.1 to 20 wt. % non-ionic surfactant; and from 0.5 to 40 wt. % of free acid equivalent of aminopolycarboxylate; and from 0.5 to 3.8 wt. % of free acid equivalent of selected hydroxamate, wherein the amount of phosphate is at most 1.0 wt. %; and wherein the amount of phosphonate is at most 1.0 wt. %.Type: ApplicationFiled: May 17, 2022Publication date: August 1, 2024Applicant: Conopco Inc., d/b/a UNILEVERInventors: Robert John Carswell, Katherine Mary Thompson, Marc Philip Woolfall
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Publication number: 20240253852Abstract: A container for unit dose liquid detergent pouches, said container comprising a lid and a base, wherein said base and top are co-operable so as to form a closed container and which is openable to access the contents by pulling them apart, said lid comprising paper with a weight average cellulose fibre length of from 1 to 5 mm, said container comprising a plurality of unit dosed detergent products and wherein said base comprises paper with a weight average cellulose fibre length of at least 2 mm.Type: ApplicationFiled: May 10, 2022Publication date: August 1, 2024Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Ross David Ashton, Kieran Dean OWENS
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Publication number: 20240253877Abstract: A package comprising at least one layer of biodegradable material and containing a plurality of unit dose products, at least one unit dose product comprising a detergent composition comprising hydrogenated castor oil within a sealed compartment formed by a water soluble film.Type: ApplicationFiled: April 6, 2022Publication date: August 1, 2024Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Ross David Ashton, Kieran Dean OWENS
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Publication number: 20240252412Abstract: The present invention is in the field of antiperspirant compositions, in particular, compositions comprising antiperspirant actives. Disclosed is an antiperspirant composition comprising (i) lecithin; (ii) a non-ionic surfactant having a HLB value lower than 4.7 or higher than 8.6; (iii) at least one organic compound selected from fatty acid having 10-22 carbons, and fatty alcohol which is selected from oleyl alcohol, isostearyl alcohol, lanolin alcohol, heptanol, octanol, decanol, and nonanol; and (iv) a cosmetically acceptable carrier; wherein said composition comprises less than 30% of water; wherein said composition comprises at least 3% of said lecithin by weight of the composition. Also disclosed is a non-therapeutic method of reducing perspiration comprising a step of topical application of the antiperspirant composition.Type: ApplicationFiled: May 11, 2022Publication date: August 1, 2024Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Xiaoke LI, Weichong WANG
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Publication number: 20240253599Abstract: The invention proposes a wiper device for wiping a window of a motor vehicle, comprising a head of a wiper arm, a housing of a drive motor for driving the head of the wiper arm, a circulation channel for circulating cleaning liquid to the wiper, extending through the drive motor housing and the head of the wiper arm. The device enables a simpler definition of the liquid circulation channel.Type: ApplicationFiled: July 27, 2022Publication date: August 1, 2024Applicant: VALEO SYSTEMES D'ESSUYAGEInventors: Quentin FAURIOL, Benjamin BANNES, Nicolas KUCHLY, Pascal RENOUX, Ga¿tan BESSON
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Publication number: 20240252737Abstract: Medical device packaging comprising: a box comprising a first compartment and a second compartment, the first and second compartments being independently openable to reveal contents of the first and second compartments respectively; a cover moveable between a closed position and an open position and which, when placed in the closed position on the box, prevents the first and second compartments from being opened; instructions for use of the device provided on a foldable portion of the box, the instructions for use only being fully visible when the cover is placed in the open position and the foldable portion is moved from a folded to an unfolded position, wherein the first compartment is configured for storing a medicament vial or cartridge and the second compartment is configured for storing an injection device which may be an on body injector (“OBI”).Type: ApplicationFiled: June 13, 2022Publication date: August 1, 2024Applicant: Teva Branded Pharmaceutical Products R&D, Inc.Inventors: Mark Destefano, Daniel Davenport
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Publication number: 20240253600Abstract: A streamlined windscreen wiper comprises a longitudinal wiper blade, fairing comprising a central mounting and at least one end cap, at least one adapter element fixed to the central mounting which comprises a central web and two legs, one of said at least one end caps being articulated to said adapter element, and a retention means comprising a first portion formed in said adapter element and engaging a complementary second portion extending from a lower surface of the central mounting, the first portion of the retention means comprises a tongue extending from the central web of the adapter element at a longitudinal extremity thereof.Type: ApplicationFiled: July 13, 2022Publication date: August 1, 2024Applicant: VALEO SYSTEMES D'ESSUYAGEInventors: Nathalie LALOI, Guillaume BARRET, Pierre SEVELLEC
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Publication number: 20240255502Abstract: A method involves detecting in a sample an autoantibody binding specifically to one or more from Gluk1, Gluk2, Gluk3, Gluk4 and Gluk5, preferably Gluk2. An autoantibody binds specifically to one or more from Gluk1, Gluk2, Gluk3, Gluk4 and Gluk5, preferably Gluk2. A diagnostically useful carrier with a solid phase with an immobilized polypeptide contains one or more from Gluk1, Gluk2, Gluk3, Gluk4 and Gluk5, preferably Gluk2 or a variant thereof. The autoantibody can be used for diagnosing a neurological autoimmune disease or a cancer.Type: ApplicationFiled: August 10, 2022Publication date: August 1, 2024Applicants: FUNDACIÓ DE RECERCA CLÍNIC BARCELONA-INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER, Institució Catalana de Recerca i Estudis Avançats (ICREA)Inventors: Josep Dalmau, Lidia Sabater, Francesc Graus
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Patent number: 12048692Abstract: Methods for treating chronic obstructive pulmonary disease (COPD) in a patient are disclosed. In the methods, a patient having COPD is selected for treatment based on the patient's peak inspiratory flow rate (PIFR) and percent predicted force expiratory volume in one second (FEV1); and a bronchodilator is administered to the selected patient using a nebulizer. Administration of a bronchodilator to patients having low PIFR and a percent predicted FEV1 less than 50 percent using a nebulizer as the inhalation delivery device provides significantly greater improvements in trough FEV1 and trough forced vital capacity (FVC) compared to administration of a bronchodilator to such patients using a dry powder inhaler.Type: GrantFiled: April 21, 2023Date of Patent: July 30, 2024Assignee: THERA VANCE BIOPHARMA R&D IP, LLCInventors: Christopher Noel Barnes, Glenn D. Crater, Edmund J. Moran, Srikanth Pendyala
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Patent number: 12048765Abstract: The present invention provides a liposome encapsulating an autoantigen, wherein the liposome has a size comprised from 500 to 15000 nm and the liposome membrane comprises phosphatydilserine (PS) in an amount comprised from 10 to 40% by weight with respect to the total membrane liposomal composition. Pharmaceutical or veterinary compositions comprising a therapeutically effective amount of said liposome are also provided. Further, the invention provides liposomes and pharmaceutical or veterinary compositions as defined above for use as a medicament, particularly for the treatment of autoimmune diseases. Finally the present invention provides liposomes and pharmaceutical or veterinary compositions as defined above for use in the restoration of tolerance to self in a patient suffering from an autoimmune disease.Type: GrantFiled: January 16, 2015Date of Patent: July 30, 2024Assignees: FUNDACIO INSTITUT D'INVESTIGACIÓ EN CIÈNCIES DE LA SLUT GERMANS TRIAST PUJOL, FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA, INSTITUCIÒ CATALANA DE RECERCA I ESTUDIS AVANCATSInventors: Daniel Maspoch Comamala, Antonia Maria Cano Sarabia, Marta Vives Pi, Irma Pujol Autonell, Juan Verdaguer Autonell
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Patent number: 12049202Abstract: A system for cleaning a plurality of sensors of a motor vehicle includes a plurality of devices for spraying a cleaning fluid onto the sensors and a cleaning fluid storage reservoir. The cleaning system includes a distribution circuit connected to the storage reservoir and to which each of the spray devices is connected via a solenoid valve. The cleaning system further includes an electronic management unit for controlling the operation of at least the distribution circuit. In addition, the cleaning system includes an electronically controlled pump, the electronic control unit of which modifies a parameter pertaining to the flow of the cleaning fluid in the distribution circuit.Type: GrantFiled: September 25, 2019Date of Patent: July 30, 2024Assignee: VALEO SYSTÈMES D'ESSUYAGEInventor: Marcel Trebouet
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Patent number: 12049500Abstract: The present invention relates to antibodies having specificity to Nectin-4 and uses thereof.Type: GrantFiled: March 31, 2022Date of Patent: July 30, 2024Assignees: EMERGENCE THERAPEUTICS GmbH, UNIVERSITE D'AIX-MARSEILLE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT JEAN PAOLI & IRENE CALMETTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS-Inventors: Jack Elands, Florence L'Hospice, Xavier Préville, Daniel Olive, Marc Lopez
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Patent number: 12048693Abstract: The present invention relates to a compound of general formula (I), wherein R1 is OCH2CH2OCH3 or OCH3, R?1 is H or OH, R2 is Cl, F, Br or I, with the proviso that when: R1 is OCH2CH2OCH3 then R?1 is H, R1 is OCH3 then R?1 is OH, its pharmaceutically acceptable salts and/or optical isomers, tautomers, solvates or isotopic variations thereof. The invention also relates to said compounds for use in the treatment of cancer, namely solid tumor cancer, and preferably those selected from melanoma, colon, lung, pancreas, kidney, Merkel carcinoma, squamous cell carcinoma, prostate, breast and bladder. The invention also relates to a pharmaceutical composition comprising said compounds.Type: GrantFiled: January 4, 2019Date of Patent: July 30, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ CÔTE D'AZURInventors: Thierry Passeron, Rachid Benhida, Pascal Dao, Gian Marco De Donatis, Anthony Martin
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Patent number: 12050088Abstract: A screening element in the form of a sintered monolithic body has an outer face and an opposing inner face with an area of the faces greater than 100 cm2 and the mean thickness Em between the faces greater than 4 mm. At least a portion of the outer face is textured such that Ai decreases from the inner face from a value of i greater than at least 50, A75?0.2×A0 and A95<0.9×A0, 0.03×A0<A95<0.5×A0 and A100<0.1×A0. Ai being the area occupied by the material alone along a plane i of internal section at the intermediate thickness Ei and i corresponding in percentage to the fraction of the mean thickness Em at plane i.Type: GrantFiled: July 2, 2021Date of Patent: July 30, 2024Assignee: SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEENInventors: Jérôme Brulin, Matthieu Graveleau, Alexane Margossian
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Patent number: 12049607Abstract: Disclosed is a detergent composition (F) for domestic or industrial use including, as thickener, a self-invertible inverse latex including an aqueous phase including: a) a crosslinked anionic polyelectrolyte (P) consisting of: —at least one monomer unit derived from at least one monomer chosen from the elements of the group consisting of acrylic acid, methacrylic acid, 2-carboxyethylacrylic acid, itaconic acid, maleic acid, 3-methyl-3-[(1-oxo-2-propenyl)amino]butanoic acid, the carboxylic function of the monomers being in free acid, partially salified or totally salified form; and—at least one monomer unit derived from a polyethylenic crosslinking monomer (AR), b) ethylenediaminedisuccinic acid in trisodium salt form.Type: GrantFiled: December 8, 2020Date of Patent: July 30, 2024Assignee: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPICInventors: Miruna Bodoc, Aurelie Colas
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Publication number: 20240248096Abstract: Early detection of lysosomal storage diseases (LSDs) including Mucopolysaccharidosis Type I (MPS I) and Pompe Disease can greatly improve patient outcome as each disease can be fatal once symptoms emerge. Screening for MPS I and Pompe Disease using biological samples including dried blood spots (DBS), buccal swab, peripheral blood mononuclear cells (PBMCs), or white blood cells (WBCs) is described. The disclosed methods and assays provide a robust way to screen newborns for LSDs. The disclosed methods and assays can also allow rapid prediction of whether a patient with LSD will develop an immune response to enzyme replacement therapy (ERT), thus improving treatment for patients with LSDs. The disclosed methods and assays can also further reduce the number of false positives caused by pseudo deficiency cases of LSD, such as MPS I and Pompe Disease.Type: ApplicationFiled: February 7, 2024Publication date: July 25, 2024Applicant: Seattle Children's Hospital d/b/a Seattle Children's Research InstituteInventors: Sihoun Hahn, Christopher Collins, Remwilyn Dayuha, Fan Yi
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Publication number: 20240246937Abstract: The invention discloses a synthesizing method of benzimidazole derivant and intermediate, which is characterized by the following: proceeding arylation among aryl halide and primary amine; adopting L-pro as additive, cuprous iodide as catalyst; proceeding molecular arylation coupling reaction for aryl iodide or aryl bromide and primary amine; adopting iodo phenylamine compound and bromophenylamine compound as starting material; synthesizing the material through several-step transformation.Type: ApplicationFiled: April 28, 2022Publication date: July 25, 2024Applicants: MERCK SHARP & DOHME LLC, MSD R&D (CHINA) CO., LTD.Inventors: George Madalin GIAMBASU, Andrew M. HAIDLE, Brett A. HOPKINS, James P. JEWELL, Matthew A. LARSEN, Charles A. LESBURG, Ping LIU, Qinglin PU, Sulagna SANYAL, Phieng SILIPHAIVANH, Matthew TUDOR, Catherine M. WHITE, Xin YAN, Lianyun ZHAO, Xiao Mei ZHENG, William P. KAPLAN, Michaelyn Claire LUX, Derun LI, Rebecca JOHNSON
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Publication number: 20240251173Abstract: A driving assistance system including at least one optical sensor and at least one associated protection device with an optical element that is transparent and mounted so as to be able to rotate. The protection device includes at least one acquisition element for acquiring at least one item of information representative of at least one angular position of the optical element on capture of an image. The system further includes a processing unit configured to detect the presence of at least one defect in the optical element, to receive the item of information representative of the angular position of the optical element, to determine at least one angular position of the defect in the optical element based thereon, and to use image processing to remove the defect in the captured image, taking into account the determined angular position of the defect in the optical element.Type: ApplicationFiled: May 17, 2022Publication date: July 25, 2024Applicant: VALEO SYSTEMES D'ESSUYAGEInventor: Olivier MARROUX
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Publication number: 20240250541Abstract: Systems, methods, and articles for a portable power case are disclosed. The portable power case is comprised of at least one battery and at least one PCB. The portable power case has at least two access ports, at least two leads, or at least one access port and at least one lead and at least one USB port. The portable power case is operable to supply power to an amplifier, a radio, a wearable battery, a mobile phone, and a tablet. The portable power case is operable to be charged using solar panels, vehicle batteries, AC adapters, non-rechargeable batteries, and generators. The portable power case provides for modularity that allows the user to disassemble and selectively remove the batteries installed within the portable power case housing.Type: ApplicationFiled: April 3, 2024Publication date: July 25, 2024Applicant: LAT Enterprises, Inc., d/b/a MediPak Energy SystemsInventors: Laura Thiel, Giancarlo Urzi, Carlos Cid
