Abstract: A main body includes an input component that receives a load. A pressure-sensitive sensor detects the load received by the input component. A drive unit performs a predetermined operation. A drive controller activates the drive unit when the load detected by the pressure-sensitive sensor reaches a predetermined load threshold. A detection controller changes the predetermined load threshold in accordance with the rate of change in the load detected by the pressure-sensitive sensor.

Abstract: A hair grasping device having a handle with hollow fingers, a trigger slidably attached to the handle, a number of grips slidably attached within the hollow fingers connected to the trigger. Each of the grips has a first and a second arm, a central post, and an extended position and retracted position. When in the retracted position, the arms are forced against the central post by the hollow fingers, and when in the extended position, the arms are forced away from the central post, creating a clearance between the arms and the central post.

Abstract: A tissue holding assembly for endothelial implantation comprising an open frame having legs for engaging a stem, such that said frame is insertable between a stroma and a Descemet's membrane, said frame being coated with a biological adhesive for adhering to a perimeter of a section of the Descemet's membrane to adhere the section of the Descemet's membrane to the frame for surgical separation of said section by cutting therearound, wherein said frame further comprises a heating element around its inner perimeter.

Abstract: A novel and useful system and method of time traveling source code debugging including several advanced capabilities that significantly improve the source code debugging process. Upon hitting a breakpoint or opening a dump file, the debugger travels to the future which can be altered by a user by modifying code on the fly (live coding) and receiving immediate feedback to validate bug fixes. Visual annotations including values of variables and expressions are provided as a heads up display effectively flattening time and space. A pivoting capability allows a user to switch the execution context of the code at any time. Point in time links that store the state of the debugging session can be created and activated. An asynchronous collaboration and messaging system enables multiple participants to share a debugging session. An optional redaction capability is also provided for obscuring or replacing sensitive private information.

Abstract: A novel and useful system and method of time traveling source code debugging including several advanced capabilities that significantly improve the source code debugging process. Upon hitting a breakpoint or opening a dump file, the debugger travels to the future which can be altered by a user by modifying code on the fly (live coding) and receiving immediate feedback to validate bug fixes. Visual annotations including values of variables and expressions are provided as a heads up display effectively flattening time and space. A pivoting capability allows a user to switch the execution context of the code at any time. Point in time links that store the state of the debugging session can be created and activated. An asynchronous collaboration and messaging system enables multiple participants to share a debugging session. An optional redaction capability is also provided for obscuring or replacing sensitive private information.

Abstract: A pharmaceutical composition having a pharmaceutically active ingredient (API) that is poorly soluble in water, the pharmaceutical composition obtained by a process, which generates a dosage form containing the pharmaceutical composition. Use of the generated dosage form for the treatment of hypercholesterolemia.

Abstract: Provided herein are antibodies that specifically bind Tau and methods of using the same.

Abstract: A speed reducer arrangement (200) for a line retraction device (100), including at least one lug (4) fixed on a surface of a rotatable hub (2) and configured to rotate along with the hub (2); at least one brake shoe (5) having at least one groove (8) extending therethrough and configured to at least partially receive the at least one lug (4), such that, as the hub (2) rotates, the at least one brake shoe (5) is configured to slidably move along the at least one groove (8) from an inactivated position, wherein the at least one brake shoe (5) is located nearest the center of the hub (2) to an activated position, wherein the at least one brake shoe (5) contacts at least one contact surface of the line retraction device (100) to thereby slow the rotation of the hub (2); and at least one biasing member (6) configured to urge the at at least one brake shoe (5) towards the inactivated position.

Abstract: The present invention relates to a health monitoring system comprising an implantable sensor configured to measure impedance within a body tissue of the subject resulting from an electrical current flowing through said body tissue, wherein the body tissue is sub-dermal or subcutaneous tissue of said subject, the sensor including a powering and communication circuit having a coil configured to be powered by an electromagnetic field and to communicate with external devices.

Abstract: A modular lavatory monument assembly configured to be positioned in the interior of an aircraft. The modular lavatory monument assembly includes first, second, third and fourth walls that cooperate to form an outer shell that defines a lavatory interior. The fourth wall includes an alcove extending outwardly therefrom. The assembly also includes a sink module positioned in the alcove, a mirror module positioned above the sink module in the alcove, and a door positioned on one of the second or third walls.

Abstract: The invention relates to a laser printing method that includes the following steps: (a) the provision of a receiver substrate (4); (b) the provision of a target substrate (5) comprising a transparent substrate (50) one surface of which has a coating has a coating (51) constituted of a solid metal film; (c) the localized irradiation of the said film (51) through the said transparent substrate (50) by means of a first laser (6) in order to reach the melting temperature of the metal in a target zone of the said film which is in liquid form; (d) the irradiation of the said liquid film through the said transparent substrate by means of a second laser on the said target zone defined in the step (c), in order to form a liquid jet in the said target zone and bring about the ejection thereof from the substrate in the form of molten metal; (e) the depositing on the receiver substrate of a molten metal drop over a defined receiving zone, with the said drop solidifying upon cooling.

Abstract: Embodiments herein are directed to topical formulations of a compound represented by the formula (I), salt, metabolite, prodrug, or hydrate thereof along with a solvent, and a base. The compound is a PDE4 inhibitor and the topical formulations may be used to treat dermatological conditions such as, but not limited to, atopic dermatitis, seborrheic dermatitis, alopecia, contact dermatitis, psoriasis, urticaria, eczema, burns, sunburn, pancreatitis, hepatitis, lichen planus, scleritis, scleroderma, dermatomyositis, itching associated with any of the preceding conditions or a combination thereof.

Abstract: The object of the invention is an inflatable watercraft (1) (SUP—stand up paddling) with an embedded drive and having a specially shaped recess in the center, preferably in the center of gravity of the watercraft (1), into which a housing (2, 2?) of a drive assembly is inserted before the watercraft is filled with air. While the watercraft (1) is filled with air, the air pressure firmly fixes the housing (2, 2?) of the drive assembly to a proper position. The housing (2, 2?) accommodates the drive assembly that comprises a storage battery (4), an electric motor (5), a compressor (3) and an electronic circuit (8), wherein the drive assembly is provided with a flow-through channel (6), in which a drive screw (7) is arranged, and both the input and the output sides of the flow-through channel (6) are protected by grates.

Abstract: Disclosed is a supply device for supplying cutouts to a machine from an inventory configured in several adjacent stacks of cutouts; the device includes a manipulator to transfer, by batch, the cutouts from the inventory to the machine. This device further includes a pressing unit to compress at least one stack that is adjacent to the one from which the manipulator removes cutouts. Also disclosed is a corresponding method.

Abstract: A method comprising: administering an effective amount of a topical dipyridamole to a subject in need thereof due to a disorder selected from the group consisting of keratitis, corneal abrasion and corneal ulcer.

Abstract: A percussive instrument mallet includes a molded head, a shaft having an optionally threaded nose, and a rigid insert fixed completely within the head. The insert has an inner profile including threads or other protrusions that mate with the nose of the shaft, and an outer profile that is embedded in the mold material. An outer portion of the insert includes a weighting ring that is also embedded in the mold material. The method includes selecting a tool with an optionally threaded nose and a central bore, threading or otherwise securing an insert onto the nose of the tool, supporting a weight ring on the insert; placing the threaded insert and weight ring in a mold, molding the head while over-molding the weight ring and insert, drawing air out of the head through the central bore, disengaging the tool from the insert, and attaching a mallet shaft into the insert.

Abstract: The present invention provides a cationic lipid which is able to be used for nucleic acid delivery to the cytoplasm. A cationic lipid according to the present invention is, for example, a compound represented by formula (1a) or a pharmaceutically acceptable salt thereof. (In formula (1a), each of L1 and L2 independently represent an alkylene group having 3-10 carbon atoms; each of R1 and R2 independently represent an alkyl group having 4-22 carbon atoms or an alkenyl group having 4-22 carbon atoms; X1 represents a single bond or —CO—O—; and ring P represents one of formulae (P-1) to (P-5).)(In formulae (P-1) to (P-5), R3 represents an alkyl group having 1-3 carbon atoms.

Abstract: This photovoltaic power generation device is provided with: a mounting bracket which is fixed to a roof and on which a frame, arranged on the ridge-side end of a solar cell module, and a frame, arranged on the eave-side end of a solar cell module, are mounted; and a securing bracket for securing the frames to the mounting bracket. The ridge-side edge of the mounting bracket is inclined in the eaves-ridge direction and the girder direction of the roof.

Abstract: A method of manufacturing a light emitting module is provided. A plurality of light-emitting diodes are aligned on an elongated base board. By a dispenser, an uncured paste of sealing material is continuously applied on a plurality of light-emitting diodes aligned on the elongated base board. The applied paste of sealing material is cured.

Abstract: The present disclosure relates to circuits, systems, and methods of operation for a memory device. In an example, a memory device includes a plurality of memory cells, each memory cell having a variable impedance that varies in accordance with a respective data value stored therein; and a read circuit configured to read the data value stored within a selected memory cell based upon a variable time delay determination of a signal node voltage change corresponding to the variable impedance of the selected memory cell.