Abstract: An illumination module assembly includes: a first housing part that includes a connector and a positioning window, and can be fastened to a base surface; a second housing part that includes a counterpart connector, which is configured to create a connection with the connector of the first housing part, and has an inner wall section bordering a light exit opening, an outer wall section, and a connecting wall section that connects the inner wall section and the outer wall section; and an operating circuit that includes at least one component being arranged on a component side of a printed circuit board. The printed circuit board is fastened to the second housing part and arranged between the inner wall section and the outer wall section, such that a printed circuit board bottom opposite the component side faces the connecting wall section.

Abstract: The invention relates to a cleaning device (100) intended for spraying at least one fluid onto a surface to be cleaned of a motor vehicle, such as an optical sensor of an optical detection system, in which a movable piston (3), sliding inside a hollow body (1) about a stationary rod extending along a longitudinal axis (X) and carrying a cleaning fluid distribution element (8, 9) at one end, allows a fluid to be conveyed towards the distribution element (8, 9) via passage channels (12) arranged between the piston and the rod and having different axial dimensions.

Abstract: Antiballistic armour plate includes a ceramic body including a hard material, provided, on its inner face, with a back energy-dissipating coating. The ceramic body is monolithic. The constituent material of the ceramic body includes grains of ceramic material having a Vickers hardness that is higher than 15 GPa, and a matrix binding the grains, the matrix including a silicon nitride phase and/or a silicon oxynitride phase, the matrix representing between 5 and 40% by weight of the constituent material of the ceramic body. The maximum equivalent diameter of the grains of ceramic material is smaller than or equal to 800 micrometres. The constituent material of the ceramic body has an open porosity that is higher than 5% and lower than 14%. The metallic silicon content in the material, expressed per mm of thickness of the body, is lower than 0.5% by weight.

Abstract: A system for in-line controlling of the ultrasonic welding of plastic components of an electronic cigarette, in which plastic components are welded to one another at a welding zone to define a welded group; the plastic components are such that the welded group has an air passage duct having a first open end and a second open end. The system includes: a chamber for receiving the welded group; a closure for closing the first open end; air supply for supplying air into the chamber.

Abstract: This electric current transmission cable includes a non-anodized bare conductor based on aluminum or an aluminum alloy having a hydrophilic external specific surface intended to be in contact with the atmospheric environment, and an inside volume intended to conduct an electric current. The external specific surface of the bare conductor has a first roughness parameter, defined as the arithmetic mean deviation, measurable by profilometry, of peaks and valleys in comparison to a predetermined average profile over a reference length or surface, equal to or greater than 1.9 ?m. In addition, the inside volume of the bare conductor has oxygen doping of its aluminum-based or aluminum alloy-based components at a ratio equal to or greater than 20%, to a depth of at least 300 nm with respect to the external specific surface.

Abstract: The invention relates to means and methods for removing a proteolytic cleavage site from a protein comprising providing a cell that expresses pre-mRNA encoding the protein with an anti-sense oligonucleotide that induces skipping of the exonic sequence that encodes the proteolytic cleavage site, the method further comprising allowing translation of mRNA produced from the pre-mRNA.

Abstract: A data sonification system for representing a plurality of channels of numerical information is described wherein the rate of the periodic modulation is itself used as a vehicle for carrying information of at least one component of the multidimensional numerical data. The data sonification system includes a plurality of audio waveform generator elements. Each of the audio waveform generator elements generates an associated audio frequency waveform. Each audio frequency waveform has an audio frequency parameter and at least one timbre modulation parameter having a settable value. The timbre modulation parameter affects the timbre of the audio waveform. The data sonification system includes a mapping element for associating aspects of multidimensional numerical data with the timbre modulation parameter of each audio frequency waveform. The mapping element sets the value of the timbre modulation parameter in response to multidimensional numerical data and/or periodic modulation.

Abstract: Paving compositions comprising asphalt cement, wherein the asphalt cement may have a with a pen value greater than 50 dmm at 25° C., and the composition may further include a an aminated wax, a rejuvenator and/or a polymeric component. Paving structures include a substrate pavement layer with a tack coat applied thereto, and methods of making a paving structure include applying a tack coat to a substrate pavement layer, wherein the tack coat comprises asphalt cement, wherein the asphalt cement may have a with a pen value greater than 50 dmm at 25° C., and the tack coat may further include a an aminated wax, a rejuvenator and/or a polymeric component.

Abstract: The auto-centering of an optical element within a barrel is provided. The optical element is mounted in a cavity of the barrel. A first surface of the optical element engages a seat provided in the cavity. A retaining ring is threaded on the barrel, through complementary barrel and ring threads. The retaining ring engages a peripheral region of a second surface of the optical element, thereby securing the optical element between the seat and the retaining ring. The profile of the barrel threads and the spatial profile of the peripheral region of the second surface are selected in view of an auto-centering condition whereby any decentering of the retaining ring and a corresponding tilt of the retaining ring have counterbalancing effects on the centering of the optical element. Optical assemblies and a mounting method are provided.

Abstract: A gas-liquid-solid three-phase slurry bed industrial reactor capable of achieving continuous operation comprises an inlet gas distribution component composed of a false bottom and inlet gas distribution tubes, one or more layers of heat exchange tube components used for heating/cooling the bed, one or more layers of liquid-solid separator components capable of being cleaned automatically, an outlet gas-liquid-solid entrainment separation component located in the upper portion of the interior of the reactor and used for removing liquid foam and solid entrainments, a plurality of layers of solid concentration uniform distribution devices used for reducing the catalyst concentration gradient and the inlet-outlet temperature difference of the reactor, a flow guiding device located on a component support beam and used for preventing catalyst accumulation, and auxiliary systems including a filter-backflush system and a washing system.

Abstract: The invention relates to a hydraulic connector, particularly for a motor vehicle windscreen wiper system. The connector is designed to be mounted on a wiper blade fitted with a perforated pipe carrying cleaning and de-icing fluid, and comprises at least one inlet coupling suitable for connection to a fluid feed, and at least one distributor provided with at least one outlet coupling designed to be connected to the perforated pipe. The connector also includes at least one internal path for carrying the fluid from the inlet coupling to the distributor. Thus, by means of the presence of the internal path through the connector, the inlet coupling can be positioned at various locations on the connector, without feeding directly into the distributor.

Abstract: Techniques and systems for providing services to a mobile device allow settings on the mobile device to be provisioned over the air. In response to a request for mobile service subscription options received from the mobile device, data relating to mobile service subscription options, for selection by a user of the mobile device, may be sent to the mobile device over a wireless communication path. A selection of one or more subscription options may be received from the mobile device over the wireless communication path, and a service corresponding to the selected subscription options may be activated in response to the selection. Settings associated with the selected subscription options may be downloaded over the air to the mobile device, which may store the settings to enable the mobile device to access the subscription.

Abstract: A tubular reactor that produces maleic anhydride from a gas mixture containing n-butane and oxygen includes a first reaction zone including an inlet for the gas mixture and a second reaction zone including an outlet for a reaction gas mixture, a plurality of tubes extending in an axial direction through the first and second reaction zones, a temperature control system, configured for controlling a reaction temperature in each of the reaction zones independently, includes a heat transfer system for each of the reaction zones configured for controlling the temperature of a liquid coolant flowing through one of the reaction zones, and a circulation pumping system configured for controlling flow conditions of the liquid coolant flowing through the reactor and one of the heat transfer systems, and a preheating arrangement configured for preheating the gas mixture such that the gas mixture enters the first reaction zone at a predefined inlet temperature.

Abstract: The invention relates to an article (I) that in at least one region (2) consists of a transparent or translucent material, in particular of glass, wherein the article (I) comprises a dynamic moire pattern in the transparent or translucent region (2), and wherein the moire pattern comes about by superimposing at least two, preferably precisely two, laser-engraved grid structures (3), which at least in regions are visually separated from each other. The grid structures (3) are located: in different layers (4) inside the transparent or translucent region (2); or in at least one layer (4) inside and in a coating (5) of at least one surface of the transparent or translucent region (2); or in at least one first layer (4) inside the transparent or translucent region (2) and at least one second virtual layer (6) that is produced by reflecting the first layer (4) at a reflecting surface (7).

Abstract: A novel and useful system and method of time traveling source code debugging including several advanced capabilities that significantly improve the source code debugging process. Upon hitting a breakpoint or opening a dump file, the debugger travels to the future which can be altered by a user by modifying code on the fly (live coding) and receiving immediate feedback to validate bug fixes. Visual annotations including values of variables and expressions are provided as a heads up display effectively flattening time and space. A pivoting capability allows a user to switch the execution context of the code at any time. Point in time links that store the state of the debugging session can be created and activated. An asynchronous collaboration and messaging system enables multiple participants to share a debugging session. An optional redaction capability is also provided for obscuring or replacing sensitive private information.

Abstract: The invention concerns a detection system (1) intended to equip a motor vehicle. This detection system (1) comprises at least one optical sensor (2) delimited by at least one optical surface (20), the shape and orientation of which define a detection field (21) of the optical sensor (2), and at least one cleaning device (3) for cleaning this optical surface (20). The cleaning device (3) comprises a delivery ramp (4) for delivering at least one cleaning and/or drying fluid, said delivery ramp (4) being movable, relative to the optical surface (20), between a first so-called rest position in which it does not deliver any fluid and a second position. According to the invention, in each position of the movement of same between the first and second positions, the delivery ramp (4) is situated outside the detection field (21) of the optical sensor (2).

Abstract: The present invention relates to the field of disorders of the central nervous system, in particular neurological and psychiatric disorders, and the prevention and/or treatment thereof. In particular, the present invention relates to the finding that soluble amyloid precursor protein ? (sAPP?) presents a particular binding site, which allows for binding to the GABABR1a receptor, thereby causing an agonistic effect through specific binding to Sushi domain 1 of GABABR1a. As a result, the frequencies of excitatory and inhibitory postsynaptic currents are reduced. Accordingly, the invention provides compounds able to interfere with the association of sAPP? with Sushi domain 1 of GABABR1a and as such with selective impairment of GABABR1a beneficial in neurological and psychiatric disorders. The invention as well provides methods and (high content) screening assays for the production of said compounds.

Abstract: A nock insert may have an axis of elongation defining an axial direction and radial directions, a bowstring reception surface adapted to receive a bowstring, and an insert portion adapted for insertion into an arrow body. The nock insert may have one or more centering features having one or more spring tabs. Each spring tab may have a first end attached to the insert portion and a second free end extending axially from the first end and having a contact surface. The contact surfaces of each spring tab may be inherently biased outwardly in a radial direction and adapted to be radially deflected upon insertion of the insert portion into the arrow body.

Abstract: The present invention provides a method of obtaining miRNA biomarkers by data-search of up-regulated microRNAs (miRNAs) in cancer and screening the miRNA biomarkers to identify cancer kind- and stage-specific miRNA biomarker(s) using cancer cells, tissues and biological fluids. This invention includes obtaining lung cancer-specific miRNA biomarkers including early (Stage I) lung cancer miRNA biomarkers and identification of anti-cancer miRNA (complementary miRNA, DNA and their derivatives) in order to ameliorate diseases. This invention relates to novel utility of nanowell electrodes to detect target molecules in biological samples. The invention teaches methods to increase sensitivity of nanowell electrodes to detect target molecules including miRNA, RNA and DNA in biological samples to diagnose cancer and other diseases and monitoring prognosis and response to therapy.

Abstract: A cleansing composition for cleansing the skin, comprising by weight of the composition, — 20 to 65 wt. % of one or more polyols; and —5 to 25 wt. % of thickeners, comprising a combination of: a) inorganic thickener selected from silica, chalk, talc, clay and combinations thereof; b) cellulosic thickener selected from cellulose, cellulose ether, cellulose ester and combinations thereof; wherein the weight ratio of the inorganic thickener to the cellulosic thickener is in the range of 4:1 to 40:1; —4 to 12 wt. % of non-soap anionic surfactant; —0 to 8 wt. % of amphoteric surfactant; and wherein the weight ratio of the one or more polyols to the thickeners is in the range of 1:1 to 13:1 and wherein the viscosity of the composition is in the range of 200 to 400 Pa-s, measured at 25° C. after 1 minute at 5 rpm.