Abstract: A washing machine and washing method thereof comprises an inner tub, an outer tub and solid particles as washing medium. The inner tub, of which the inner wall is provided with lifting ribs protruding inward, rotates under the driving power of a driving device. Inside the washing machine, a storage tank for storing particles connects to the inner tub through a discharge channel for recycling particles and a feeding channel for putting in particles, and an air suction device is arranged on the feeding channel. Through alternate clockwise and counter-clockwise rotates of the inner tub, clothes and particles within are overturned in all directions, thus clothes and particles get better blended, and the cleaning rate gets improved. Meanwhile, putting-in and recycling particles through an air suction device is conducive to 100% recycling of particles.

Abstract: This invention relates to an ophthalmic lens with a low reflection both in the ultraviolet region and in the visible region, comprising a substrate provided on its rear main face with a multilayered antireflective coating (3-7 layers) comprising a stack of at least one layer with a high refractive index and at least one layer with a low refractive index, having a mean reflection factor on the rear face in the visible region Rm lower than or equal to 1.15%, a mean light reflection factor on the rear face in the visible region Rv lower than or equal to 1%, a mean reflection factor RUV on the rear face between 280 nm and 380 nm, weighted by the function W(?) defined in the ISO 13666:1998 standard, lower than 5%, for angles of incidence of 30° and 45°, the antireflective coating outer layer being a silica-based layer. The lens according to the invention does especially prevent the reflection of the UV radiation produced by light sources located behind the wearer.

Abstract: A hydraulic machine includes oscillating radial cylinders close to an external shell of a crown or star of cylinder-piston groups. The pistons of the groups are made sliding on a crank shaft with throw or on interposed concentric elements, which create an alternative movement in the oscillating radial cylinders. The oscillating cylinders are placed in contact with a spherical oscillation surface made on a body or shell of the hydraulic machine. A passage of the hydraulic liquid to and from the oscillating radial cylinder, to create feeding and discharge of the cylinder, is formed through at least a flat lateral external surface on the side of the oscillating cylinder, parallel to an oscillation plane of the cylinders, to and from a feeding channel on a lateral body or cover of the hydraulic machine.

Abstract: The present invention relates to a method for treating a Leber congenital amaurosis in a patient harboring the mutation c.2991+1655 A>G in the CEP290 gene, comprising the step of administering to said patient at least one antisense oligonucleotide complementary to nucleic acid sequence that is necessary for preventing splicing of the cryptic exon inserted into the mutant c.2291+1655 A>G CEP290 mRNA.

Abstract: A door module for a vehicle lavatory that includes a bi-fold door having a first panel and a second panel each having an inner surface and an outer surface. The first and second panels are pivotably connected together by a living hinge. The living hinge includes a hinge member that extends between first and second securing members, wherein the first securing member extends along and is attached to an inner edge of the first panel and the second securing member extends along and is attached to an inner edge of the second panel.

Abstract: A light transmitting device is extremely adaptable and provides a great amount of light for a given battery power. A flexible elongated polymeric light transmitting element has first and second ends with at least one LED immediately adjacent (e. g. touching but not embedded in) one or both of the ends so that light is efficiently transmitted from an LED along the light transmitting element. At least one battery powers the LED. A module including a printed circuit board, electrical switch, and the LED and battery, is positioned within a housing having open ends so that one or both ends of the light transmitting element receive light directly from an LED. A number of button batteries, or a rechargeable battery with USB port, may be mounted on the module, and the circuitry of the printed circuit board may include an integrated circuit.

Abstract: In one aspect, the invention relates to compounds having the formula: where R1, R2a, R2b, R3—R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Abstract: An apparatus for controlled delivery of a flow of breathing gas to the respiratory tracts of a user includes a blower unit adapted to provide a gas flow, a nasal cannula with first and second outlets, and first and second gas paths connecting the blower unit to the first and second outlets, respectively. The Characteristics of the gas flow through each outlet can be controlled, sensed and/or adjusted independently.

Abstract: A method of acoustically fitting a hearing aid comprises providing a plurality of audible tones, each having a predetermined frequency through stereo headphones. The tones are provided at specific sound pressure in each ear. The patient changes the relative sound pressure in each ear until a perceived direction of source of the tone is in front of the patient. The amplification or attenuation requirements of a hearing aid are modified based on the difference in the sound pressures required for the left and right ears of the patient for perceived directional sameness for each frequency band-pass channel.

Abstract: A centrifugal brake assembly comprises at least one pawl, at least one biasing member, and a rotor. The at least one pawl includes a base from which a circular portion extends. The rotor includes at least one receiving portion having a notched portion configured and arranged to receive the circular portion. One of the at least one pawl and the rotor has a curved slotted portion, the at least one biasing member being seated within the curved slotted portion, and another of the at least one pawl and the rotor having a curved elongated protrusion extending in line with the curved slotted portion and the at least one biasing member. The at least one pawl is pivotable about the circular portion relative to the rotor, and the at least one pawl is configured and arranged to engage a stop member when the at least one pawl is in an engaged position.

Abstract: Various techniques and apparatus permit fabrication of superconductive circuits and structures, for instance Josephson junctions, which may, for example be useful in quantum computers. For instance, a low magnetic flux noise trilayer structure may be fabricated having a dielectric structure or layer interposed between two elements or layers capable of superconducting. A superconducting via may directly overlie a Josephson junction. A structure, for instance a Josephson junction, may be carried on a planarized dielectric layer. A fin may be employed to remove heat from the structure. A via capable of superconducting may have a width that is less than about 1 micrometer. The structure may be coupled to a resistor, for example by vias and/or a strap connector.

Abstract: The invention relates to a wiper blade assembly for the windows of a motor vehicle, comprising a longitudinal support (10) intended to receive a pressure application vertebra (20) and a wiper blade (30) and a wiper accessory (40) carrying a device (42a, 42b) for distributing and projecting a washer liquid wherein the accessory is intended to be assembled with the longitudinal support (10). According to the invention, the longitudinal support (10) comprises means for fixing said accessory (40) on said support.

Abstract: Described herein is an electronic device. The electronic device includes a unity gain buffer having an input coupled to an input node to receive an input voltage and an output coupled to an output node. A current sink circuit operates in a sleep mode in an absence of a sink current flowing into the output node, and operates in a sinking mode to sink the sink current from the output node to a reference supply node when the sink current flows into the output node.

Abstract: A pre-fabricated assemblies and methods of use for coating substrates are described. The pre-fabricated assembly includes at least two layers in a stack, each layer includes at least one raw material. The raw material in each layer may be a dielectric material. One type of stack has one outer layer as an exposed layer. One type of stack has an exposed portion with each layer, and a portion of all layers is exposed. In use, a stack in a pre-fabricated assembly is positioned in a vacuum chamber system and energy is delivered sequentially to the exposed layer, removing at least a portion of each exposed layer. Each layer becomes an exposed layer and is deposited on the substrate in a sequential manner. The pre-assembled raw material stack is used to fabricate a multi-layered coating, such as a multi-layered coating for an optical or ophthalmic article.

Abstract: The present invention relates to a transparent optical article comprising at least one dye at least partially inhibiting light having a wavelength ranging from 400 to 460 nm and at least one selective optical brightener that emits light by fluorescence at a wavelength ranging from 400 to 460 nm. The optical brightener acts as a means for at least partially balancing the color imparted to the transparent optical article by the dye, thus allowing for perception of said optical article as less yellow, and even colorless to an user or an observer.

Abstract: Disclosed is a sheet of laminate comprising a paper component laminated to a plastic component, said sheet comprising, and severable into, plurality of discrete wrappers, each comprising opposed first (1) and second edges (2) and opposed third (3) and fourth edges (4), wherein the paper component of each wrapper comprises: (i) a first adhesive-coated portion (6) located along substantially the entire length of said first edge; (ii) a second adhesive-coated portion (7) located between said first and second edges and along a part of the length of said third edge; and, (iii) a third adhesive-coated portion (8) located opposite said second portion along a part of the length of said fourth edge.