Abstract: The present invention relates to a zero-phosphate machine dish wash composition in unit dose format comprising non-phosphate builder, alkali percarbonate, a manganese bleach catalyst in relatively low amounts and one or more polycarboxylate polymers. The builder comprises one or more from methylglycine-N,N-diacetic acid and/or one or more salts thereof, citric acid and/or one or more salts thereof, and glutamic acid-N,N-diacetic acid and/or one or more salts thereof. The polycarboxylate polymers have a weight average molecular weight of between 1000 and 100,000, the polymers comprising at least 20 mol-% of acrylate monomers and from 0 to 40 mol-% of maleate monomers. The composition provides improved tea stain removal upon use.

Abstract: Disclosed is a cleansing composition having pH of at least 9, said composition comprising: (i) 20 to 85 wt % anionic surfactant; and, (ii) a silver(I) compound having silver ion solubility (in water at 25° C.) of at least 1×10?4 mol/L, at a level equivalent to silver content of 0.01 to 100 ppm, wherein the free alkali content of said composition is less than 0.01%. The composition is a robust and improved cleansing composition with a stable colour.

Abstract: The present invention concerns subject matter connected to or making use of lgLON5, lgLON5 fragments and variants of lgLON5 and lgLON5-fragments. In particular the present invention relates to a use of a polypeptide comprising one or more sequences of IgLON5, an lgLON5-fragment or a variant thereof for the diagnosis of a disease, in vitro methods for diagnosing such a disease, a polypeptide comprising one or more sequences of lgLON5, an lgLON5-fragment or a variant thereof or a nucleic acid encoding said polypeptide for use in the treatment of a disease, a pharmaceutical composition comprising such polypeptide, a method for treating such a disease, an autoantibody binding to IgLON5, an lgLON5-fragment or a variant thereof, a method for isolating such autoantibody, a medical or diagnostic device comprising such autoantibody or such polypeptide and a test kit for the diagnosis of a disease, which test kit comprises such autoantibody and/or such polypeptide.

Abstract: The present invention provides an anti-human Notch4 antibody or a Notch4 binding fragment thereof that may have neutralizing activity against human Notch4, as well as a pharmaceutical composition comprising the same as the active ingredient. The present inventors obtained a mouse anti-human Notch4 antibody that has high neutralizing activity and binding affinity towards human Notch4 and determined the complementarity determining region (CDR) sequence of said mouse anti-human Notch4 antibody. This enabled the production of a humanized antibody comprising the variable region of heavy and light chains as well as the CDR sequence of said mouse anti-human Notch4 antibody.

Abstract: Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-? protein.

Abstract: The invention relates to a method of analyzing particles, in particular particles of diameter less than 1 ?m, the method comprising the following steps: firing laser shots into a cold plasma (45) at low pressure; using an optical spectrometer device (60) to acquire emission spectra of the light emitted by the plasma as a result of the laser shots, in such a manner that for each acquired spectrum, an acquisition period begins no later than 100 ns after firing the laser shot; and analyzing the particles present in the plasma on the basis of the emission spectra. A system for detecting and/or analyzing particles by performing the method.

Abstract: A pharmaceutical composition comprising: an active ingredient consisting of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide, salt thereof, or solvate of the foregoing; and (i) a compound, a 5% (w/w) aqueous solution or suspension of which has a pH of 8 or more, and/or (ii) silicic acid, salt thereof, or solvate of the foregoing is a highly stable pharmaceutical composition, wherein under humidified and heated storage conditions, the decomposition of said compound is sufficiently reduced, or the gelation on the surface of the pharmaceutical composition is sufficiently inhibited.

Abstract: An injection device comprises a volume, an injection device to inject a jet of liquid reagent into the volume, at least one first impactor positioned in the volume, and a first heating device to heat the first impactor. The first heating device comprises a first heating member having a device having a thermally conductive zone in contact with the first impactor or defining the first impactor. A resistive heating element is housed in the device and arranged to heat the thermally conductive zone.

Abstract: The present invention relates to a method for tinting optical films comprising: (a) coating onto an optical film a liquid coating composition comprising, in a water miscible organic solvent, 1 part of cellulose acetate butyrate (CAB), from 0.1 to 2 parts by weight of dicyclohexyl phthalate, from 0.1 to 1 part by weight of isocyanato-alkyltrialcoxysilane, and at least 0.5 moles of H2O per mole of hydrolysable alcoxy groups of isocyanatoalkyltrialcoxysilane, (b) submitting said coated composition to a drying step so as to form an image-receiving CAB layer on the optical film, (c) printing the dried image-receiving CAB layer with a sublimation dye by means of a thermal transfer printer, (d) submitting the resulting printed film and image -receiving CAB layer to a thermal treatment so as to transfer the printed sublimation dye from the image-receiving layer to the underlying optical film, and (e) removing the image-receiving CAB layer by means of a suitable solvent.

Abstract: The invention relates to a vehicle seat comprising a seat portion and a backrest connected to the seat portion by a hinge mechanism. A seat element selected from among the backrest and the seat portion comprises a shell, which is made of a plastic material and the side edges of which are overmolded onto composite reinforcement inserts. Each of the inserts comprises a core perpendicular to the medium plane of the seat element, and two side flanges parallel to the medium plane of the seat element. The insert is formed by assembling two composite parts having an L-shaped cross-section and forming a portion of the core and one of the side flanges of the insert.

Abstract: A system and method for detecting and locating an insulation flaw in a solar generator on a spacecraft. The solar generator comprises a plurality of flaps. Each flap bears at least one solar cell that is connected to an electrical distribution network and electrically insulated from the flap. Each flap is connected, by a first load and by a second load, to a first electrical line and a second electrical line, respectively. The ratio of the impedances of the first load and of the second load of a flap being denoted as an impedance ratio of the flap. The solar generator comprises at least two flaps exhibiting different respective impedance ratios. The system comprises a component for evaluating the currents flowing in the first and second electrical lines, and a detector for detecting and locating an insulation flaw in the solar generator based on the evaluations of the currents.

Abstract: A method for manufacturing sintered refractory grains containing Cr2CO3 from an initial refractory product including one or more chromium that includes: A) optionally, \crushing the starting refractory material; B) grinding a filler, comprising said starting refractory material in a liquid medium to obtain a suspension of particles of said starting refractory material; C) preparing a starting mixture including at least 1 wt % of particles of the suspension obtained during the preceding step; D) shaping the starting mixture into the shape of a preform; E) optionally drying the preform obtained in step D); F) sintering the preform so as to obtain a sintered body; G) optionally grinding the sintered body; and H) the optional selection by particle size.

Abstract: A battery is provided. The battery includes a plurality of electrochemical cells connected in series with each other and adapted for each generating an electric current from an oxidation-reduction reaction between an oxidizing fluid and a reducing fluid. The battery also includes, for each electrochemical cell, a control device for controlling the voltage across the terminals of the cell. The battery also includes a voltage regulator device electrically connected to the cell so that the control device measures the voltage across the terminals of the cell, increased by an offset voltage across the terminals of the regulator device.

Abstract: A system and method to discover subscriber content affinity and make corresponding recommendations is disclosed. A particular embodiment includes collecting digital content from a plurality of content feeds; receiving a subscriber-provided affinity indicator from a subscriber; filtering the digital content based on the subscriber-provided affinity indicator to produce filtered content; tracking interactions with the filtered content by the subscriber; and automatically determining implicit subscriber affinity based on subscriber interactions with the filtered content.

Abstract: A device for securing a mobility device in a mobility vehicle or on a lifting device that is installed in or on a mobility vehicle or trailer.

Abstract: The present invention is in the field of ice cream shaping, in particular it is relating to a heated tool to imprint a pattern a frozen confectionery product, and especially a heated tool that melts away a channel of an outer coating layer of a frozen confectionery, thereby creating a peelable frozen confectionery product. It is an object of the present invention to provide a shaping tool that is suitable for making cleaner grooves in frozen confectionery products. We have found that a shaping tool that comprises of at least one heated element provides a molten channel in the outer surface of a frozen confection.

Abstract: Flat wiper blade for use in windscreen wiper modules of vehicles, essentially consisting of a wiping rubber in addition to two spring rails, extending in the longitudinal direction of the wiper blade, spaced apart from one another and receiving the wiping rubber in a subsection between them, which each respectively project over the wiping rubber on the wiper blade longitudinal sides and with at least one jet or injection strip provided on one longitudinal side of the wiper blade, having at least one injection or washing duct with a large number of jet or injection openings for application of a washing and cleaning fluid to a vehicle windscreen and which, with use of clip-like fixtures spanning the wiper blade on the upper side of the wiper blade, is retained on the external peripheries of the spring rails.

Abstract: A power adapter (10) comprises a power conversion unit (11), a charging interface (12), an exception detection unit (13), and an exception processing unit (14). The power conversion unit forms a charging loop with a terminal (20) through the charging interface, so as to charge a battery (21) of the terminal. The exception detection unit detects whether an exception occurs on the charging loop. When the exception occurs on the charging loop, the exception processing unit controls the charging loop to enter into a protection state. The power adapter can improve the security of a charging process. Also provided are a terminal, and a method for processing an exception of a charging loop.

Abstract: The disclosure concerns an infrared emitter is provided comprising a metalized membrane emitting infrared light in operation. The membrane comprises a two dimensional array of infrared wavelength sized through-holes and to each side a thin metal layer comprising also an array of through-holes. The through-holes are arranged as a two-dimensional periodic array and each of said through-holes have a cross section having a maximum and a minimum dimension of less than any wavelength of the emitted infrared light. The peak wavelength of the emitted infrared light is proportional to the periodicity of the through-holes. At least one of the metal layers is connected to an electrical current source that provides an electrical current that heats at least one of the metal layers so that a narrow bandwidth and highly directive light beam of infrared light is emitted. The membrane is arranged on a membrane support and both are made of a material that resists to temperatures higher than 400°.

Abstract: The invention relates to a device (II) for three-dimensional focusing in a microscope (I) with a given resolution, comprising:—a detector (119) making it possible to determine, in a given measuring plane, a phase and intensity image of an electromagnetic field resulting from the interaction of an incident light wave with a reference object (105) situated in a reference medium with a given index and having a complex refractive index, the real part and/or the imaginary part of which differs from the real part and/or the imaginary part, respectively, of the refractive index of the reference medium;—computation means (121) making it possible to determine a three-dimensional position variation of the reference object (105) from at least one phase and intensity image.