Abstract: Cleaning composition, which is a dry shampoo, comprising a base and propellant, wherein the base comprises sebum absorber which comprises magnetic particles, wherein the magnetic particles have a particle size in the range of from 4 nm to 50 nm, and wherein the magnetic particles are coated with a stabilizing dispersing agent, and wherein the magnetic particles are dispersed in a liquid carrier.

Abstract: The present invention is drawn to an optical article comprising: (a) a photochromic substrate comprising at least one photochromic dye, and (b) an interference coating having a specific gradient thickness providing for a gradient reflectance. It also pertains to a process for making such an optical article.

Abstract: The invention relates to a method of receiving digital data transmitted on a coded serial digital transmission modulated on a noisy channel with non-stationary equalisation attenuation. Digital data are stored (33) associating a value of quality of transmission with the information elements received, and a mutual information value Ik is computed (34) for each value of said quality of transmission. Said value of quality of transmission consists of an equivalent signal/noise plus interference ratio calculated as a function of said method of equalisation on the basis of various signal/channel noise ratio values measured for the various temporal symbols of information elements received of the signal received corresponding to one and the same information element and according to interference due to said waveform.

Abstract: In one aspect, the invention relates to a compound of the structure: or a pharmaceutically acceptable salt thereof, and a crystalline form of this compound, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this compound; methods of using this compound; and processes for preparing this compound.

Abstract: The invention relates to systems and methods of maintaining revealed and unrevealed balances that both belong to a user, but the user is aware only of the revealed balance. In this manner, the system can give the user an impression that a value (e.g., a cash amount or other value) has been gained or lost by transferring the value between the revealed and unrevealed balances of the user, even though no gain or loss actually occurred. The unrevealed balance may include a payout from a real-world wager. Thus, payout may be revealed to the user in a manner that the user believes that the payout was won by the user through a game or other interactive media, even though the payout belongs to the user based on the payout. Other changes in value to the unrevealed and revealed balances may occur as well.

Abstract: The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9 and SEQ ID NO: 10.

Abstract: A sensor for measuring conductivity of a fluid containing dissolved ions, particularly for measuring conductivity of salt water, features a cylindrical tube (57) of poorly conductive material such as glass, a first electrode (51A) and a second electrode (51B) inside the tube, connected together (56) to maintain a common electrical potential, a first transformer (52,53) concentrically arranged around the tube (57) to drive current through the fluid in the tube, and a second transformer (54, 55) arranged to sense a value of the current flowing in the fluid, and a digital processing circuit (62) coupled to receive an output signal of the second transformer, and to derive therefrom a value representing the conductivity of the fluid. The sensor is adapted to be towed behind a research ship, or to be deployed on an autonomous underwater vehicle (AUV) or the like. Current signals are preferably processed by digital switching measurement technology (dMST).

Abstract: An arm (1) comprises a main body (5), a tilting barrel group (2) fitted to the main body (5) and a locking device (10). The locking device (10) is acting between the main body (5) and the barrel group (2) and manually operable between a locked position, in which the tilting of the barrel group (2) is prevented, and a release position, in which the barrel group (2) is released from said body (5). Said locking device (10) comprises at least one sliding bolt (20) or plug, partially housed in the main body (5) so that, in the locked position, a portion thereof engages the barrel group (2). The device is further comprising a safety catch element (100), acting between the barrel group (2) and the main body (5), which acts in conjunction with the bolt (20) to maintain the locked position.

Abstract: The present invention relates to a powder of molten grains of yttria-stabilized zirconia, said grains having the following chemical analysis, in weight percent on the basis of the oxides: ZrO2+HfO2: remainder up to 100%; 11.8%?Y2O3?18.6%; 0.07%?Al2O3?1.8%; TiO2?0.6%, provided that 0.5<Al2O3 0.3%?TiO2 if 0.6%<Al2O3; and other oxides: ?2.0%.

Abstract: The present invention is within the field of biomolecule purification. More closely the invention relates to chromatographic purification of insulin using a specific kind of shell beads having an inner core and an outer functionalized layer. The method enables purification at high flow rates and high purity, over 90%.

Abstract: A washing machine and a washing method, comprises an inner cylinder, an outer cylinder, and solid particles as washing medium. The inner cylinder is driven into rotation by a driver device. The inner cylinder has arranged on the inner wall thereof scraper blades that protrude inwards and are bent along the wall of the inner cylinder. The scraper blades drives the particles into obliquely upward or obliquely downward movements and flipping, thus allowing for more fully mixing clothes with the particles, for simplified washing process, while also for improved cleaning rate, and for facilitated recycling of the particles.

Abstract: A touch detecting assembly, a touch sensitive device, and a portable electronic apparatus are provided. The touch detecting assembly (100) comprises: a substrate (1); and a plurality of induction units (2) disposed on the substrate (1) and not intersecting with each other, each induction unit (2) comprising an induction body (20), and a first electrode (21) and a second electrode (22) connected with the induction body (20) respectively. Each induction body (20) has a plurality of empty parts (24), and the plurality of empty parts (24) are arranged in a predetermined pattern to define a current passage (25) for increasing a resistance between the first electrode (21) and the second electrode (22).

Abstract: A device, method, and system for managing authorization for rendering of digital media recordings by a networked rendering device are disclosed. The device includes a processor and a memory. The device receives metadata identifying a recording of a specific audio performance, and searches for a source providing the recording. The device obtains a token authorizing the source to deliver the recording to the rendering device. The device provides the token to the source, receives the recording from the source, and renders the recording. An agent may serve as an intermediary between the rendering device and the source.

Abstract: Broadband antenna system comprising a plurality of antenna elements and a plurality of amplifiers; wherein every antenna element of said plurality of antenna elements is configured for operating in a predetermined frequency range and is associated with an amplifier of said plurality of amplifiers which is configured for said predetermined frequency range; said plurality of antenna elements covering a broadband range.

Abstract: The present invention is directed to compounds such as: formula wherein linker is independently selected from the group consisting of —S—, —S—S—, —S—(CH2)n-, —NH—, —NH—(CH2)n-, —O—, —SO2-, arylene, heteroarylene; R1 is selected from the group consisting of straight or branched C4-C20 alkyl, straight or branched C4-C20 alkenyl, straight or branched C4-C20 alkynyl, each optionally interrupted with at least one NH, C5-C7 saturated cycloalkyl or heteroalkyl ring, C5-C12 aromatic or heteroaromatic ring, each optionally substituted with at least one group selected from —COOH, —NH2, C1-C8 alkoxy, C1-C5 amidyle, C1-C5 carboxyl, halogen; and R2 is independently selected from the group consisting of H, OH, SH, NH2, NO2, halogen, CN, C1-C8 alkoxy, C1-C5 carboxylic acid, straight or branched C1-C8 alkyl, straight or branched C2-C10 alkenyl, straight or branched C2-C12 alkynyl each optionally substituted by at least one substituent selected from the group consisting of C1-C5 alkoxy, C1-C5 carboxylic acid, OH, SH, NH2, hal

Abstract: The present disclosure relates to the field of oncology, more particularly to the field of melanoma. Provided are methods of treating melanoma, particularly advanced cutaneous melanoma, with a combination of pharmaceutical agents comprising MDM4-specific antagonists (such as an inhibitor of the MDM4-p53 interaction or a molecule that decreases MDM4 protein stability) or MDM4-MDM2 dual inhibitors (i.e., molecules that disrupt the interactions between p53 and MDM2 and p53 and MDM4) and one or more chemotherapeutic agents such as for example alkylating agents (i.e., Dacarbazine (DITC) or melphalan), alkylating-like agents (i.e., cisplatin or carboplatin) or mitotic inhibitors (taxanes docetaxel or paclitaxel) and PI3K-AKT, B-RAF and MEK inhibitors. Further provided are pharmaceutical formulations of MDM4-specific antagonists (be it an inhibitor of the MDM4-p53 interaction or a molecule that decreases MDM4 protein stability) or MDM4-MDM2 dual inhibitors (i.e.

Abstract: A coupling device for timepieces that includes an entry wheel, a coupling wheel, and a first exit wheel. The coupling wheel is disposed substantially coplanar to the plane of rotation of the entry wheel and of the first exit wheel and is adapted to tilt relative to the plane of rotation to occupy a first coupling position in which the coupling wheel meshes with the first exit wheel and a second coupling position in which the coupling wheel is decoupled from the first exit wheel. The device also includes a movable element to control the change of position between the first and the second position of the coupling wheel. The coupling wheel defines an axis of rotation that can be inclined relative to the normal to the plane of rotation of the entry wheel and of the first exit wheel by being mounted pivotably at each of the ends thereof.

Abstract: The visual perception of a lens wearer is not only along the gaze direction, but also has a non-zero transverse extension, which is called perceptual span. Perceptual span is skewed to extend further in the reading direction, i.e., the line portion to be read next relative to the line portion that was just read. A technique is provided that determines a pair of progressive ophthalmic lenses that take such perceptual span into account.

Abstract: A system and method for scanning items for purchase in a retail environment is provided that has the ability to scan multiple items within its scan field of view simultaneously or nearly simultaneously in a multi-scanning type of configuration. In addition to the simultaneous scanning, the identity of each scanned item is discovered and then added to a running tally of items to be later purchased in a point of sale terminal.

Abstract: The safety and proper performance of jet aircraft engines requires that any contamination of jet fuel, for example by water or by improper contaminants, be filtered (removed) before delivery of the fuel, through hoses, to the fuel tanks of the aircraft. Coalescing devices and filters in the fuel delivery system are used to attain this result. A typical problem is that filter materials chemically react with surfactants, and this causes the filter subsequently to “disarm” or fail to perform its function of removing water, which can lead to delivery of fuel containing excessive water. A solution to this problem is to pre-test the fuel for such surfactants by feeding a small fuel sample that has been mixed with “challenge water” through a smaller ‘representative’ test filter and monitor the performance. Using a fluorescent dye in the “challenge water,” the amount of water that passes the test filter is detected, compared with a baseline data and fuel quality determination is made.