Abstract: A centrifugal brake assembly comprises a pawl and a biasing member. The pawl includes a base from which a circular portion and a triangular protrusion extend. A rotor includes a receiving portion having a notched portion. The notched portion is configured and arranged to receive the circular portion. One of the pawl and the rotor has a slotted portion, and the other of the pawl and the rotor has a protrusion. The slotted portion is configured and arranged to receive the protrusion and the biasing member. The pawl is pivotable about the circular portion relative to the rotor and the triangular portion of the pawl is configured and arranged to engage a stop member when the pawl is in an engaged position. The base contacts the rotor in the engaged position to reinforce the pawl.

Abstract: In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Abstract: The invention is directed to methods for treating hypertension or heart failure using compounds having the formula: wherein: Ar, r, Y, Z, Q, W, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. In particular embodiments, the invention uses compounds having formula IIIa, IVa, Va: These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity.

Abstract: [Problem] In a system that transmits content data from a content replay device to a content output device, to prevent a deterioration in audio quality or video data picture quality while being able to increase the simplicity of a setting-altering operation without requiring complicated signal processing.

Abstract: A radiation sensor of the type having a packaged radiation source and detector, which includes an isolator that blocks propagation within the package of radiation from the source to the detector, in order to improve signal to noise ratio of the sensor. The isolator is formed by appropriately formed surfaces of the package.

Abstract: The invention relates mainly to a test bench (10) for a radial bearing (14) suitable for being interposed between two members (12, 16) that are movable relative to each other in rotation, the test bench being characterized in that it comprises a radial force measurement device (18) for measuring radial forces exerted on said bearing (14), a radial acceleration measurement device (20) for measuring radial accelerations to which said bearing (14) is subjected, and an electronic calculation unit (26) in communication with the radial force measurement device (18) and with the radial acceleration measurement device (20). The invention also relates to a method of establishing a behavior relationship for the radial bearing (14).

Abstract: Apparatus and methods enable active compensation for unwanted discrepancies in the superconducting elements of a quantum processor. A qubit may include a primary compound Josephson junction (CJJ) structure, which may include at least a first secondary CJJ structure to enable compensation for Josephson junction asymmetry in the primary CJJ structure. A qubit may include a series LC-circuit coupled in parallel with a first CJJ structure to provide a tunable capacitance. A qubit control system may include means for tuning inductance of a qubit loop, for instance a tunable coupler inductively coupled to the qubit loop and controlled by a programming interface, or a CJJ structure coupled in series with the qubit loop and controlled by a programming interface.

Abstract: A container includes a chamber to hold a medication, a lockable lid that covers an opening of the chamber, a biometric sensor, a scale, and one or more processors. The container may store prescription information indicating how often the medication should be provided. The container may measure a weight of the medication held by the chamber using the scale. The container may receive biometric information sensed by the biometric sensor. The biometric information may indicate a biometric feature of a person attempting to open the container. The container may selectively unlock the lockable lid based on at least one of the prescription information, the weight of the medication, or the biometric information.

Abstract: Disclosed is an optical article, preferably an ophthalmic lens, including a substrate having at least one main surface and a precursor coating of an anti-fog coating, the precursor coating in direct contact with either the main surface of the substrate, or with a first coating, when the main surface of the substrate is coated with a first coating, the precursor coating being formed by a deposition of at least one hydrophilic compound A on the substrate or on the first coating, including an inner portion in which the compound A is grafted on the substrate or on the first coating, and an outer portion that can be removed by washing and/or wiping, resulting from the deposition of the compound A, and being coated with a temporary layer, in direct contact with the compound, including at least one compound selected from the metal fluorides and the compounds including magnesium and oxygen.

Abstract: A method for manufacturing an ophthalmic lens by machining, includes the steps of providing and mounting a blank on a first supporting device having a first machining reference frame in a first position in which a lower surface of the blank is opposite the first device; machining, in the first position in the first reference frame, an upper surface of the blank, machining in a second predetermined machining reference frame which is known relative to the first at least one mechanical referencing element on the blank, and providing a second supporting device including at least one complementary mechanical referencing element configured such as to engage with the at least one mechanical referencing element so that the latter is positioned and supported on the second device in a second predetermined position.

Abstract: A method for evaluating the quality of a directed self-assembling method used for generating directed self-assembling patterns. The method for evaluating comprises obtaining at least one set of parameter values for a parameterized set of processing steps and material properties characterizing the directed self-assembling method, thus characterizing a specific directed self-assembling method used for generating a directed self-assembled pattern. The method furthermore comprises obtaining a scattered radiation pattern on the directed self-assembled pattern obtained using the directed self-assembling method characterized by the set of parameter values, thus obtaining scattered radiation pattern results for the directed self-assembled pattern. The method furthermore comprises determining based on the scattered radiation pattern results a qualification score and correlating the qualification score with the set of parameter values.

Abstract: A particle comprising: a core, comprising an optional benefit agent; an inner shell at least partially surrounding the core, said inner shell being the water insoluble product of a polymerisation reaction to form a first polymer with a glass transition temperature above and including 70 degrees Celsius, preferably above and including 80 degrees Celsius; an outer shell at least partially surrounding said inner shell, said outer shell being the water insoluble product of a polymerisation reaction to form a second polymer with a glass transition temperature below and including 35 degrees Celsius; and a deposition aid, covalently attached to the outer shell.

Abstract: The present invention provides a lubricating resin composition for personal care, wherein the composition comprises 100 parts by mass of a thermoplastic elastomer having durometer A hardness (HDA) of 10 to 40, 10 to 40 parts by mass of a water-soluble polyethylene oxide, and 20 to 60 parts by mass of a water-absorbent modified polyalkylene oxide, and wherein the composition not only maintains its superior lubricity and roughness-resistant property under a wet condition even in repeated use thereof, but also represents a low swelling ratio and no slimy feeling under a wet condition.

Abstract: The invention relates to methods for determining the clinical outcome of a patient suffering ischemic stroke, for designing an individual therapy and for diagnosing a silent cerebrovascular disease comprising determining the levels of a marker selected from DPYSL2, gelsolin, CysA, or a combination thereof, the altered expression of which in relation to a reference value allows determining the clinical outcome of a patient suffering ischemic stroke, designing for designing an individual therapy or diagnosing a silent cerebrovascular disease. Furthermore, the invention relates to a kit comprising a reagent for detecting the level of a marker selected from DPYSL2, gelsolin, CysA, or a combination thereof and to the use of the said kit in the methods of the invention.

Abstract: An example of a system that provides notary services on behalf of an application client running on a mobile device is described. The application client requests a notarization token from an application notary service client running on the same mobile device. The application notary service client utilizes a SIM card of the mobile device to generate a notarization token request which is sent to an application notary service server. The application notary service server utilizes a SIM signature validator server to validate the notarization token request and generates the notarization token for delivery to the application client via the application notary service client. The application client includes the notarization token in a request to an application server, which uses the notarization token to validate the application client for access to a function or data of the server.

Abstract: The present invention is to provide a safety monitoring system, which includes a plurality of terminal devices (e.g., smartphones) each configured to wirelessly and periodically send out a report message and a home server storing positioning data created according to the strengths of signals transmitted by each terminal device from different locations within an indoor environment (e.g., an apartment) respectively. According to the positioning data, the home server divides the indoor environment into a plurality of monitoring areas (e.g., living room, bathrooms, kitchen . . . ). When the home server receives the report message and determines the monitoring area where each terminal device is located according to the positioning data, the home server uploads entry of identification data and the monitoring area corresponding to each terminal device to a cloud server through the Internet. Thus, the current status of the carrier of each terminal device can be checked through the cloud server.

Abstract: An exemplary system and method provides a product notification and recommendation technology for monitoring a computing device to detect particular use-cases of device activity and providing a notification through a user interface that indicates at least one product corresponding to the detected particular use-cases. In this way, the product notification and recommendation technology adds a new dimension of usage-based personalization to targeted advertising that results in timely product and service recommendations.

Abstract: Disclosed is a method for printing an ink jet marking on a non-wetting surface for liquid ink, including the following steps: Depositing a first layer of ink at a first speed to provide adhesion, Depositing a second layer at a second speed in order to make the marking visible.

Abstract: A first user device and second user device may be coupled, such as by an audio interface included in the second user device. The second user device is unable to generate a registration request, and the first user device may acquire device data associated with the second user device and form the registration request. The registration request may include the device data and information associated with the first user device. The registration request may be authenticated, and activation data may be generated based on the information associated with the first user device and the device data. The activation data is forwarded to the second user device to enable the second user device to access a restricted service or data.