Patents Assigned to D
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Patent number: 9133484Abstract: A transfection agent is provided that has lower toxicity and can be applied in the clinical setting. The transfection agent comprises a peptide surfactant.Type: GrantFiled: August 26, 2009Date of Patent: September 15, 2015Assignees: 3-D MATRIX, LTD., NIPPON MEDICAL SCHOOL FOUNDATIONInventors: Daizo Yoshida, Jiro Takei
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Patent number: 9132970Abstract: The invention relates to a method for grouping together products that arrive in line and are spaced apart from each other on an infeed conveyor (2), consisting of: collecting the products on the fly by means of a pair of collectors (4) that move transversely relative to the products on said conveyor (2); moving the products collected by collector (4A) to a removal station (11) and, at the same time, replacing said collector (4A) with the second collector (4B) that, in turn, collects the products; and dropping off the products from collector (4A) to the removal station (11) and bringing said collector (4A) back to a collecting position while intersecting collector (4B).Type: GrantFiled: December 30, 2009Date of Patent: September 15, 2015Assignee: C.E.R.M.E.X. CONSTRUCTIONS ETUDES ET RECHERCHES DE MATERIELS POUR L'EMBALLAGE D'EXPEDITIONInventors: Guillaume Duchemin, Didier Mougin, David Gatos, Thierry Garnier
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Patent number: 9132173Abstract: The present invention relates to a vector for use in the treatment of Huntington's disease, which vector comprises a cholesterol 24-hydroxylase encoding nucleic acid.Type: GrantFiled: October 14, 2011Date of Patent: September 15, 2015Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris Descartes, Universite Evry Val d'essone, Centre National de la Recherche Scientifique (CNRS)Inventors: Jocelyne Caboche, Patrick Aubourg, Nathalie Cartier, Sandrine Betuing
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Patent number: 9132581Abstract: An injection blow molding (IBM) system and method for forming a plurality of parisons and molded articles. The IBM system includes an injection station having upper and lower die sets and a plurality of upper and lower mold half blocks each attached to a respective die set. Each of the upper mold half blocks has a corresponding lower mold half block with which it cooperatively defines one or more cavities for forming the exterior shape of the body of one or more of the parisons. The individual, independent attachment of the mold half blocks to the die sets allows easy individual replacement of faulty or worn mold blocks. Further, such an independent attachment configuration also permits the mold half blocks of each die set to be spaced from one another, so as to reduce thermal expansion problems and ease dimensional tolerances required for the width of the mold half blocks.Type: GrantFiled: October 18, 2013Date of Patent: September 15, 2015Assignee: R&D Tools & Engineering Co.Inventors: Randal L. Fields, Bruce A. Wardlow, David A. Brunson, Brian R. Lefebure, James R. Baldwin
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Patent number: 9133966Abstract: A device having a first part shrink-fitted with a first shrink ring, the first shrink ring being shrink-fitted with a second shrink ring exhibiting a lower thermal expansion coefficient than a thermal expansion coefficient of the first shrink ring.Type: GrantFiled: February 24, 2010Date of Patent: September 15, 2015Assignee: SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEENInventors: Christian His, Franceline Villermaux, Guillaume Belly
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Patent number: 9133328Abstract: A composition includes: a) polystyrene, the polystyrene including polybutadiene; b) vegetal fibers having a length lower than 50 ?m; and c) at least one compatibility agent including a polybutadiene maleic anhydride copolymer, the copolymer including at least 17% by weight of the copolymer of maleic anhydride. The composition is used for manufacturing a plastic composition. The plastic composition obtained by heating the composition, a sheet obtained by extruding the plastic composition, and a container obtained by thermoforming the sheet are also described.Type: GrantFiled: December 12, 2011Date of Patent: September 15, 2015Assignee: SA DES EAUX MINERALES D'EVIAN SAEMEInventor: Anne-Flore Jacob
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Patent number: 9136762Abstract: A low side driver includes a first transistor coupled in series with a second transistor at a low side voltage node for a load. A capacitance is configured to store a voltage and a voltage buffer circuit has an input coupled to receive the voltage stored by the capacitance and an output coupled to drive a control node of the second transistor with the stored voltage. A current source supplies current through a switch to the capacitance and the input of the voltage buffer circuit. The switch is configured to be actuated by an oscillating enable signal so as to cyclically source current from the current source to the capacitance and cause a stepped increase in the stored voltage which is applied by the buffer circuit to the control node of the second transistor.Type: GrantFiled: May 2, 2013Date of Patent: September 15, 2015Assignee: STMicroelectronics (Shenzhen) R&D Co. LtdInventors: Meng Wang, Tao Tao Huang
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Patent number: 9132293Abstract: A powdery composition C1 contains for 100% of the mass: 5 to 70 mass % and more particularly 10 to 50 mass % of at least one compound of formula (I): R—O-(G)x—H, wherein R is a linear saturated aliphatic radical including 12 to 22 carbon atoms, G is the remainder of a reducing sugar selected from the group including glucose, xylose and arabinose, and x is a decimal number greater than or equal to 1 and lower than or equal to 10; 95 to 30 mass % and more particularly 90 to 50 mass % of one or more alcohols of formula (II): R?—OH, wherein R? is a linear saturated aliphatic radical including 12 to 22 carbon atoms identical to or different from R as defined in formula (I), wherein at least 90 vol % of the particles have a diameter lower than or equal to 250 micrometers, more particularly a diameter lower than or equal to 150 micrometers.Type: GrantFiled: May 15, 2014Date of Patent: September 15, 2015Assignee: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPICInventors: Chantal Amalric, Alicia Roso, Agnès Gorce
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Patent number: 9133084Abstract: A process for the preparation of methanol having the process a carbon oxides per-pass conversion equal to or higher than 65%, and a selectivity to methanol formation equal to or higher than 75% by submitting carbon dioxide, carbon monoxide or a mixture of carbon monoxide and carbon dioxide to a hydrogenation reaction using a specific metal compound and specific reaction conditions of temperature, pressure, space velocity and a specific range of molar ratio of hydrogen to carbon dioxide, of hydrogen to carbon monoxide, or of hydrogen to the mixture of carbon monoxide and carbon dioxide. It further relates to a process for converting the methanol obtained into dimethyl ether or into a mixture of (C2-C8)alkene and (C1-C8)alkane.Type: GrantFiled: May 15, 2013Date of Patent: September 15, 2015Assignee: FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ)Inventors: Atsushi Urakawa, Atul Baban Bansode
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Patent number: 9134191Abstract: A resistive device which includes at least one strain gauge (12, 14) comprising silicon nanowires, a power supply (16) that has at least one current source (22, 24) able to generate a current (Ibias) for biasing the strain gauge; and acquisition means (18) able to deliver a measurement signal which can be used to determine the variation in the electrical resistance of the gauge is provided. The power supply includes a chopper (26) allowing the biasing current generated by each current source to flow through each gauge only during a fraction of an operating cycle of the device.Type: GrantFiled: June 29, 2012Date of Patent: September 15, 2015Assignees: Centre National de la Recherche Scientifique, Universite Du Sud-toulon Var, Universite D'Aix-MarseilleInventors: Wenceslas Rahajandraibe, Stéphane Meillere, Edith Kussener, Hervé Barthelemy
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Publication number: 20150250386Abstract: Implantable device (8) comprising:—a base element (1; 7);—a cover (2) attached to said base element (1; 7) so as to define a cavity arranged to receive an electronic device (4);—a metallic interlayer (3) disposed between the base element (1) and the cover (2), and arranged so as to bond the base element (1; 7) to the cover (2), wherein said metallic interlayer (3) comprises at least one diffusion barrier layer (3a) and at least one bonding layer (3b). The diffusion barrier layer (3a) may optionally also serve as an adhesion layer, or a further adhesion layer may be provided.Type: ApplicationFiled: September 26, 2013Publication date: September 10, 2015Applicant: CSEM Centre Suisse d'Electronique et de Microtechnique SA -Recherche et DeveloppementInventors: Rony Jose James, Guido Spinola Durante, Christian Bosshard
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Publication number: 20150250515Abstract: Disclosed bone screws include multiple screw elements engaged together to provide the required strength along a longitudinal direction and the required flexibility in other degrees of freedom. The disclosed bone screws have a low profile. Further, the bone screws allow fine-tuning of the compression to be applied to bones or joints. Instrumentation for implanting and orienting the bone screws is also disclosed herein.Type: ApplicationFiled: March 10, 2014Publication date: September 10, 2015Applicant: COORSTEK MEDICAL LLC d/b/a IMDSInventors: Lance Nathan Terrill, Andrew Douglas Palmer
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Publication number: 20150257004Abstract: The method, system and device examples provide for a mobile device biometric authentication that authenticates an application user via a biometric input, and thereby reduce the need to enter complex user credentials into a mobile device to gain access to a mobile application. The examples leverage the biometric recognition operations managed by the operating system of the mobile device to allow a mobile application to authenticate the user as a valid user of the mobile application. In an example, a successfully unlocking of a mobile device via a biometric input from a user is used by the mobile application to perform an authentication operation with assistance from an authentication server to authenticate the user of the mobile device as a valid user of the mobile application. As a result, the mobile application grants access to the mobile application based on the user's biometric input.Type: ApplicationFiled: March 7, 2014Publication date: September 10, 2015Applicant: CELLCO PARTNERSHIP D/B/A VERIZON WIRELESSInventors: Sankar Shanmugam, Moorthy Sengottaiyan, Sivagnanalingam Sivaganesh
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Publication number: 20150252023Abstract: The invention provides compounds of formulas (I) or (II): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: May 21, 2015Publication date: September 10, 2015Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: Robert Murray McKinnell, Daniel D. Long
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Publication number: 20150257112Abstract: A device is configured to store target location information indicating an acceptable signal strength at a target location. The device may receive a signal emitted from a base station. The signal may be received at the target location. The device may measure the signal strength of the signal at the target location. The device may transmit a signal strength message including information based on the signal strength. The signal strength message may cause the base station to adjust a power with which signals are emitted from the base station such that the signals satisfy the acceptable signal strength at the target location.Type: ApplicationFiled: March 4, 2014Publication date: September 10, 2015Applicants: Cellco Partnership d/b/a Verizon Wireless, Verizon Patent and Licensing Inc.Inventors: Sagiv Draznin, Arda Aksu, Mingxing S. Li, Donna L. Polehn, Jyothi Keshavdas, Kent W. Hughes
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Publication number: 20150250514Abstract: Disclosed bone screws include a slotted tip. The slotted design of the tip partially obviates the need for precision while implanting the bone screw. Further, the slotted tip reduces the stiffness differential between the tip of the bone screw and the bone. Yet further, the slotted tip reduces stress concentrations imparted to the bone both during insertion and under bending loads. Moreover, the slotted tip conforms to natural formations within the bone when the bone screw is inserted into the bone. Instrumentation for implanting and orienting the bone screws is also disclosed herein.Type: ApplicationFiled: March 10, 2014Publication date: September 10, 2015Applicant: COORSTEK MEDICAL LLC d/b/a IMDSInventors: Lance Nathan Terrill, Sarah Lynne Lancianese, Tyler Salem, Dain Odegaard
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Publication number: 20150256511Abstract: Systems and methods for handling an OPEN CHANNEL command from a universal integrated circuit card (UICC) of a mobile device are disclosed. In some implementations, a mobile device hosting a UICC receives, from the UICC, an initiation of an OPEN CHANNEL command with a uniform resource locator (URL) of a subscriber identity module over the air (SIMOTA) server. The mobile device signals for attempting to resolve the URL to an Internet Protocol (IP) address. Upon successfully resolving the URL to the IP address, the mobile device obtains the IP address associated with the SIMOTA server, connects to the SIMOTA server using the IP address, and returns a successful TERMINAL RESPONSE to the UICC. Upon failing to resolve the URL to the IP address, the mobile device returns an unsuccessful TERMINAL RESPONSE to the UICC.Type: ApplicationFiled: March 10, 2014Publication date: September 10, 2015Applicant: CELLCO PARTNERSHIP D/B/A VERIZON WIRELESSInventor: Praveen K. GUPTA
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Publication number: 20150252364Abstract: Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of SMN1 or SMN2. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of SMN1 or SMN2 that comprises exon 7. Methods for modulating expression of SMN1 or SMN2 using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of SMN1 or SMN2.Type: ApplicationFiled: May 16, 2013Publication date: September 10, 2015Applicants: RaNA Therapeutics, Inc., The General Hospital Corporation d/b/a Massachusetts General HospitalInventors: Arthur M. Krieg, Romesh Subramanian, James McSwiggen, Jeannie T. Lee
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Patent number: 9126999Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.Type: GrantFiled: May 31, 2013Date of Patent: September 8, 2015Assignee: EISAI R&D MANAGEMENT CO., LTD.Inventors: Roch Boivin, Eric Carlson, Atsushi Endo, Hans Hansen, Lynn D. Hawkins, Sally Ishizaka, Matthew Mackey, Sridhar Narayan, Takashi Satoh, Shawn Schiller
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Patent number: 9127065Abstract: The present invention provides for isolated anti-human-HER3 antibodies or fragments thereof. More particularly the present invention provides an isolated monoclonal antibody that specifically binds to the extracellular domain of HER-3 and competes for binding to the extracellular domain of human HER-3 with the antibody produced obtainable from hybridoma deposited as CNCM-I-4486. The antibodies described in the present invention are useful for the treatment of cancer.Type: GrantFiled: May 21, 2012Date of Patent: September 8, 2015Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre Val d'Aurelle—Paul Lamarque, Universite de Montpellier 1Inventors: Thierry Chardes, Andre Pelegrin, Christel Larbouret, Nadege Gaborit, Yassamine Lazrek